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Items: 42


Targeted inhibition of the Shroom3-Rho kinase protein-protein interaction circumvents Nogo66 to promote axon outgrowth.

Dickson HM, Wilbur A, Reinke AA, Young MA, Vojtek AB.

BMC Neurosci. 2015 Jun 16;16:34. doi: 10.1186/s12868-015-0171-5.


Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration.

Wan J, Zhao XF, Vojtek A, Goldman D.

Cell Rep. 2014 Oct 9;9(1):285-297. doi: 10.1016/j.celrep.2014.08.048. Epub 2014 Sep 25. Erratum in: Cell Rep. 2014 Oct 23;9(2):794.


Loss-of-function mutations in RSPH1 cause primary ciliary dyskinesia with central-complex and radial-spoke defects.

Kott E, Legendre M, Copin B, Papon JF, Dastot-Le Moal F, Montantin G, Duquesnoy P, Piterboth W, Amram D, Bassinet L, Beucher J, Beydon N, Deneuville E, Houdouin V, Journel H, Just J, Nathan N, Tamalet A, Collot N, Jeanson L, Le Gouez M, Vallette B, Vojtek AM, Epaud R, Coste A, Clement A, Housset B, Louis B, Escudier E, Amselem S.

Am J Hum Genet. 2013 Sep 5;93(3):561-70. doi: 10.1016/j.ajhg.2013.07.013. Epub 2013 Aug 29.


Primary ciliary dyskinesia presentation in 60 children according to ciliary ultrastructure.

Vallet C, Escudier E, Roudot-Thoraval F, Blanchon S, Fauroux B, Beydon N, Boulé M, Vojtek AM, Amselem S, Clément A, Tamalet A.

Eur J Pediatr. 2013 Aug;172(8):1053-60. doi: 10.1007/s00431-013-1996-5. Epub 2013 Apr 10.


Quantitative analysis of ciliary beating in primary ciliary dyskinesia: a pilot study.

Papon JF, Bassinet L, Cariou-Patron G, Zerah-Lancner F, Vojtek AM, Blanchon S, Crestani B, Amselem S, Coste A, Housset B, Escudier E, Louis B.

Orphanet J Rare Dis. 2012 Oct 11;7:78. doi: 10.1186/1750-1172-7-78.


Delineation of CCDC39/CCDC40 mutation spectrum and associated phenotypes in primary ciliary dyskinesia.

Blanchon S, Legendre M, Copin B, Duquesnoy P, Montantin G, Kott E, Dastot F, Jeanson L, Cachanado M, Rousseau A, Papon JF, Beydon N, Brouard J, Crestani B, Deschildre A, Désir J, Dollfus H, Leheup B, Tamalet A, Thumerelle C, Vojtek AM, Escalier D, Coste A, de Blic J, Clément A, Escudier E, Amselem S.

J Med Genet. 2012 Jun;49(6):410-6. doi: 10.1136/jmedgenet-2012-100867.


POSH is an intracellular signal transducer for the axon outgrowth inhibitor Nogo66.

Dickson HM, Zurawski J, Zhang H, Turner DL, Vojtek AB.

J Neurosci. 2010 Oct 6;30(40):13319-25. doi: 10.1523/JNEUROSCI.1324-10.2010.


Abnormal respiratory cilia in non-syndromic Leber congenital amaurosis with CEP290 mutations.

Papon JF, Perrault I, Coste A, Louis B, Gérard X, Hanein S, Fares-Taie L, Gerber S, Defoort-Dhellemmes S, Vojtek AM, Kaplan J, Rozet JM, Escudier E.

J Med Genet. 2010 Dec;47(12):829-34. doi: 10.1136/jmg.2010.077883. Epub 2010 Aug 30.


Excess of neuromuscular spindles in a fetus with Costello syndrome: a clinicopathological report.

Sinico M, Bassez G, Touboul C, Cavé H, Vergnaud A, Zirah C, Fleury-Feith J, Gettler S, Vojtek AM, Chevalier N, Amram D, Alsamad IA, Haddad B, Encha-Razavi F.

Pediatr Dev Pathol. 2011 May-Jun;14(3):218-23. doi: 10.2350/09-06-0664-CR.1. Epub 2010 Jul 26.


Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia.

Duquesnoy P, Escudier E, Vincensini L, Freshour J, Bridoux AM, Coste A, Deschildre A, de Blic J, Legendre M, Montantin G, Tenreiro H, Vojtek AM, Loussert C, Clément A, Escalier D, Bastin P, Mitchell DR, Amselem S.

Am J Hum Genet. 2009 Dec;85(6):890-6. doi: 10.1016/j.ajhg.2009.11.008.


A 20-year experience of electron microscopy in the diagnosis of primary ciliary dyskinesia.

Papon JF, Coste A, Roudot-Thoraval F, Boucherat M, Roger G, Tamalet A, Vojtek AM, Amselem S, Escudier E.

Eur Respir J. 2010 May;35(5):1057-63. doi: 10.1183/09031936.00046209. Epub 2009 Oct 19.


The scaffold protein POSH regulates axon outgrowth.

Taylor J, Chung KH, Figueroa C, Zurawski J, Dickson HM, Brace EJ, Avery AW, Turner DL, Vojtek AB.

Mol Biol Cell. 2008 Dec;19(12):5181-92. doi: 10.1091/mbc.E08-02-0231. Epub 2008 Oct 1.


A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia.

Duriez B, Duquesnoy P, Escudier E, Bridoux AM, Escalier D, Rayet I, Marcos E, Vojtek AM, Bercher JF, Amselem S.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3336-41. Epub 2007 Feb 20. Erratum in: Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6490.


UNC-51-like kinase regulation of fibroblast growth factor receptor substrate 2/3.

Avery AW, Figueroa C, Vojtek AB.

Cell Signal. 2007 Jan;19(1):177-84. Epub 2006 Aug 2.


Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155.

Chung KH, Hart CC, Al-Bassam S, Avery A, Taylor J, Patel PD, Vojtek AB, Turner DL.

Nucleic Acids Res. 2006 Apr 13;34(7):e53.


Use of short hairpin RNA expression vectors to study mammalian neural development.

Yu JY, Wang TW, Vojtek AB, Parent JM, Turner DL.

Methods Enzymol. 2005;392:186-99.


Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.

Figueroa C, Tarras S, Taylor J, Vojtek AB.

J Biol Chem. 2003 Nov 28;278(48):47922-7. Epub 2003 Sep 21.


Akt negatively regulates translation of the ternary complex factor Elk-1.

Figueroa C, Vojtek AB.

Oncogene. 2003 Aug 28;22(36):5554-61.


Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.

Hou P, Estrada L, Kinley AW, Parsons JT, Vojtek AB, Gorski JL.

Hum Mol Genet. 2003 Aug 15;12(16):1981-93.


Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.

Vojtek AB, Taylor J, DeRuiter SL, Yu JY, Figueroa C, Kwok RP, Turner DL.

Mol Cell Biol. 2003 Jul;23(13):4417-27.


Simultaneous inhibition of GSK3alpha and GSK3beta using hairpin siRNA expression vectors.

Yu JY, Taylor J, DeRuiter SL, Vojtek AB, Turner DL.

Mol Ther. 2003 Feb;7(2):228-36.


Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation.

Murphy GA, Graham SM, Morita S, Reks SE, Rogers-Graham K, Vojtek A, Kelley GG, Der CJ.

J Biol Chem. 2002 Mar 22;277(12):9966-75. Epub 2002 Jan 11.


Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.

Zhang BH, Tang ED, Zhu T, Greenberg ME, Vojtek AB, Guan KL.

J Biol Chem. 2001 Aug 24;276(34):31620-6. Epub 2001 Jun 15.


Analyses of TC21/R-Ras2 signaling and biological activity.

Graham SM, Rogers-Graham K, Figueroa C, Der CJ, Vojtek AB.

Methods Enzymol. 2001;333:203-16. No abstract available.


Prenylated Rab acceptor protein is a receptor for prenylated small GTPases.

Figueroa C, Taylor J, Vojtek AB.

J Biol Chem. 2001 Jul 27;276(30):28219-25. Epub 2001 May 2.


Negative regulation of the serine/threonine kinase B-Raf by Akt.

Guan KL, Figueroa C, Brtva TR, Zhu T, Taylor J, Barber TD, Vojtek AB.

J Biol Chem. 2000 Sep 1;275(35):27354-9.


Increasing complexity of the Ras signaling pathway.

Vojtek AB, Der CJ.

J Biol Chem. 1998 Aug 7;273(32):19925-8. Review. No abstract available.


Identification and characterization of mutations in Ha-Ras that selectively decrease binding to cRaf-1.

Winkler DG, Johnson JC, Cooper JA, Vojtek AB.

J Biol Chem. 1997 Sep 26;272(39):24402-9.


p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.

Chantry D, Vojtek A, Kashishian A, Holtzman DA, Wood C, Gray PW, Cooper JA, Hoekstra MF.

J Biol Chem. 1997 Aug 1;272(31):19236-41.


TC21 causes transformation by Raf-independent signaling pathways.

Graham SM, Vojtek AB, Huff SY, Cox AD, Clark GJ, Cooper JA, Der CJ.

Mol Cell Biol. 1996 Nov;16(11):6132-40.


Rho family members: activators of MAP kinase cascades.

Vojtek AB, Cooper JA.

Cell. 1995 Aug 25;82(4):527-9. Review. No abstract available.


Ras-Raf interaction: two-hybrid analysis.

Vojtek AB, Hollenberg SM.

Methods Enzymol. 1995;255:331-42.


A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function.

Fabian JR, Vojtek AB, Cooper JA, Morrison DK.

Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5982-6.


In vivo phosphorylation site of hexokinase 2 in Saccharomyces cerevisiae.

Kriegel TM, Rush J, Vojtek AB, Clifton D, Fraenkel DG.

Biochemistry. 1994 Jan 11;33(1):148-52.


Mammalian Ras interacts directly with the serine/threonine kinase Raf.

Vojtek AB, Hollenberg SM, Cooper JA.

Cell. 1993 Jul 16;74(1):205-14.


Evidence for a functional link between profilin and CAP in the yeast S. cerevisiae.

Vojtek A, Haarer B, Field J, Gerst J, Pollard TD, Brown S, Wigler M.

Cell. 1991 Aug 9;66(3):497-505.


CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complex.

Gerst JE, Ferguson K, Vojtek A, Wigler M, Field J.

Mol Cell Biol. 1991 Mar;11(3):1248-57.


Phosphorylation of yeast hexokinases.

Vojtek AB, Fraenkel DG.

Eur J Biochem. 1990 Jun 20;190(2):371-5.


Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein.

Field J, Vojtek A, Ballester R, Bolger G, Colicelli J, Ferguson K, Gerst J, Kataoka T, Michaeli T, Powers S, et al.

Cell. 1990 Apr 20;61(2):319-27.


The adenylyl cyclase gene from Schizosaccharomyces pombe.

Young D, Riggs M, Field J, Vojtek A, Broek D, Wigler M.

Proc Natl Acad Sci U S A. 1989 Oct;86(20):7989-93.

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