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Items: 47


Viral load assay performs comparably to early infant diagnosis assay to diagnose infants with HIV in Mozambique: a prospective observational study.

Vubil A, Nhachigule C, Loquiha O, Meggi B, Mabunda N, Bollinger T, Sacks JA, Jani I, Vojnov L.

J Int AIDS Soc. 2020 Jan;23(1):e25422. doi: 10.1002/jia2.25422.


Proportions of CD4 test results indicating advanced HIV disease remain consistently high at primary health care facilities across four high HIV burden countries.

Lamp K, McGovern S, Fong Y, Atem CD, Nfetam JBE, Nzuobontane D, Bollinger T, Jani I, Sitoe N, Kiyaga C, Senyama G, Mangwendeza PM, Mtapuri-Zinyowera S, Doi N, Peter T, Sacks JA, Vojnov L.

PLoS One. 2020 Jan 7;15(1):e0226987. doi: 10.1371/journal.pone.0226987. eCollection 2020.


Systematic review of the accuracy of plasma preparation tubes for HIV viral load testing.

Luo R, Markby J, Sacks J, Vojnov L.

PLoS One. 2019 Nov 21;14(11):e0225393. doi: 10.1371/journal.pone.0225393. eCollection 2019.


HIV viral resuppression following an elevated viral load: a systematic review and meta-analysis.

Ford N, Orrell C, Shubber Z, Apollo T, Vojnov L.

J Int AIDS Soc. 2019 Nov;22(11):e25415. doi: 10.1002/jia2.25415. Review.


Clinical Consequences of Using an Indeterminate Range for Early Infant Diagnosis of HIV: A Decision Model.

Salvatore P, Johnson K, Vojnov L, Doherty M, Dowdy D.

J Acquir Immune Defic Syndr. 2019 Nov 1;82(3):287-296. doi: 10.1097/QAI.0000000000002155.


Use of an Indeterminate Range in HIV Early Infant Diagnosis: A Systematic Review and Meta-Analysis.

Luo R, Boeras D, Broyles LN, Fong Y, Hsiao NY, Kiyaga C, Mazanderani AH, Myer L, Shapiro R, Sherman G, Penazzato M, Doherty M, Vojnov L.

J Acquir Immune Defic Syndr. 2019 Nov 1;82(3):281-286. doi: 10.1097/QAI.0000000000002104.


Point-of-care CD4 technology invalid result rates in public health care settings across five countries.

Lamp K, McGovern S, Fong Y, Abere B, Kebede A, Ayana G, Mulugeta A, Atem CD, Elat Nfetam JB, Nzuobontane D, Bollinger T, Jani I, Sitoe N, Kiyaga C, Senyama G, Mangwendeza PM, Mtapuri-Zinyowera S, Sacks JA, Doi N, Peter TF, Vojnov L.

PLoS One. 2019 Jul 5;14(7):e0219021. doi: 10.1371/journal.pone.0219021. eCollection 2019.


Performance of Cepheid Xpert HIV-1 viral load plasma assay to accurately detect treatment failure.

Sacks JA, Fong Y, Gonzalez MP, Andreotti M, Baliga S, Garrett N, Jordan J, Karita E, Kulkarni S, Mor O, Mosha F, Ndlovu Z, Plantier JC, Saravanan S, Scott L, Peter T, Doherty M, Vojnov L.

AIDS. 2019 Oct 1;33(12):1881-1889. doi: 10.1097/QAD.0000000000002303.


Reliability of plasma HIV viral load testing beyond 24 hours: Insights gained from a study in a routine diagnostic laboratory.

Hardie D, Korsman S, Ameer S, Vojnov L, Hsiao NY.

PLoS One. 2019 Jul 3;14(7):e0219381. doi: 10.1371/journal.pone.0219381. eCollection 2019.


Implementing an Indeterminate Range for More Accurate Early Infant Diagnosis.

Vojnov L, Penazzato M, Sherman G, Ghadrshenas A, Abrams EJ, Doherty M.

J Acquir Immune Defic Syndr. 2019 Nov 1;82(3):e44-e46. doi: 10.1097/QAI.0000000000002081. No abstract available.


The missed potential of CD4 and viral load testing to improve clinical outcomes for people living with HIV in lower-resource settings.

Ehrenkranz PD, Baptiste SL, Bygrave H, Ellman T, Doi N, Grimsrud A, Jahn A, Kalua T, Nyirenda RK, Odo MO, Ondoa P, Vojnov L, Holmes CB.

PLoS Med. 2019 May 29;16(5):e1002820. doi: 10.1371/journal.pmed.1002820. eCollection 2019 May.


Performance of non-laboratory staff for diagnostic testing and specimen collection in HIV programs: A systematic review and meta-analysis.

Vojnov L, Taegtmeyer M, Boeke C, Markby J, Harris L, Doherty M, Peter T, Ford N.

PLoS One. 2019 May 2;14(5):e0216277. doi: 10.1371/journal.pone.0216277. eCollection 2019.


Forecasting the global demand for HIV monitoring and diagnostic tests: A 2016-2021 analysis.

Habiyambere V, Dongmo Nguimfack B, Vojnov L, Ford N, Stover J, Hasek L, Maggiore P, Low-Beer D, Pérez Gonzàlez M, Edgil D, Williams J, Kuritsky J, Hargreaves S, NeSmith T.

PLoS One. 2018 Sep 19;13(9):e0201341. doi: 10.1371/journal.pone.0201341. eCollection 2018.


Performance of point-of-care birth HIV testing in primary health care clinics: An observational cohort study.

Meggi B, Vojnov L, Mabunda N, Vubil A, Zitha A, Tobaiwa O, Mudenyanga C, Mutsaka D, Bollinger T, Loquiha O, Peter TF, Jani IV.

PLoS One. 2018 Jun 18;13(6):e0198344. doi: 10.1371/journal.pone.0198344. eCollection 2018.


Effect of point-of-care early infant diagnosis on antiretroviral therapy initiation and retention of patients.

Jani IV, Meggi B, Loquiha O, Tobaiwa O, Mudenyanga C, Zitha A, Mutsaka D, Mabunda N, Vubil A, Bollinger T, Vojnov L, Peter TF.

AIDS. 2018 Jul 17;32(11):1453-1463. doi: 10.1097/QAD.0000000000001846.


Managing Advanced HIV Disease in a Public Health Approach.

Ford N, Meintjes G, Calmy A, Bygrave H, Migone C, Vitoria M, Penazzato M, Vojnov L, Doherty M; Guideline Development Group for Managing Advanced HIV Disease and Rapid Initiation of Antiretroviral Therapy.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S106-SS110. doi: 10.1093/cid/cix1139.


Significant Patient Impact Observed Upon Implementation of Point-of-Care Early Infant Diagnosis Technologies in an Observational Study in Malawi.

Mwenda R, Fong Y, Magombo T, Saka E, Midiani D, Mwase C, Kandulu J, Wang M, Thomas R, Sherman J, Vojnov L.

Clin Infect Dis. 2018 Aug 16;67(5):701-707. doi: 10.1093/cid/ciy169.


Where have all the children gone? High HIV prevalence in infants attending nutrition and inpatient entry points.

Kiyaga C, Urick B, Fong Y, Okiira C, Nabukeera-Barungi N, Nansera D, Ochola E, Nteziyaremye J, Bigira V, Ssewanyana I, Olupot-Olupot P, Peter T, Ghadrshenas A, Vojnov L.

J Int AIDS Soc. 2018 Feb;21(2). doi: 10.1002/jia2.25089.


Rapid Serological Tests Ineffectively Screen for HIV Exposure in HIV-Positive Infants.

Urick B, Fong Y, Okiira C, Nabukeera-Barungi N, Nansera D, Ochola E, Nteziyaremye J, Bigira V, Ssewanyana I, Olupot-Olupot P, Peter T, Ghadrshenas A, Vojnov L, Kiyaga C.

J Acquir Immune Defic Syndr. 2018 Mar 1;77(3):331-336. doi: 10.1097/QAI.0000000000001609.


Scaling up HIV viral load - lessons from the large-scale implementation of HIV early infant diagnosis and CD4 testing.

Peter T, Zeh C, Katz Z, Elbireer A, Alemayehu B, Vojnov L, Costa A, Doi N, Jani I.

J Int AIDS Soc. 2017 Nov;20 Suppl 7. doi: 10.1002/jia2.25008.


The WHO public health approach to HIV treatment and care: looking back and looking ahead.

Ford N, Ball A, Baggaley R, Vitoria M, Low-Beer D, Penazzato M, Vojnov L, Bertagnolio S, Habiyambere V, Doherty M, Hirnschall G.

Lancet Infect Dis. 2018 Mar;18(3):e76-e86. doi: 10.1016/S1473-3099(17)30482-6. Epub 2017 Oct 20. Review.


Impact of SMS/GPRS Printers in Reducing Time to Early Infant Diagnosis Compared With Routine Result Reporting: A Systematic Review and Meta-Analysis.

Vojnov L, Markby J, Boeke C, Penazzato M, Urick B, Ghadrshenas A, Harris L, Ford N, Peter T.

J Acquir Immune Defic Syndr. 2017 Dec 15;76(5):522-526. doi: 10.1097/QAI.0000000000001526. Review.


The performance of BD FACSPresto™ for CD4 T-cell count, CD4% and hemoglobin concentration test in Ethiopia.

Gebremicael G, Belay Y, Girma F, Abreha Y, Gebreegziabxier A, Tesfaye S, Messele Z, Assefa Y, Bellete B, Kassa D, Vojnov L.

PLoS One. 2017 Apr 27;12(4):e0176323. doi: 10.1371/journal.pone.0176323. eCollection 2017.


Point-Of-Care p24 Infant Testing for HIV May Increase Patient Identification despite Low Sensitivity.

Meggi B, Bollinger T, Mabunda N, Vubil A, Tobaiwa O, Quevedo JI, Loquiha O, Vojnov L, Peter TF, Jani IV.

PLoS One. 2017 Jan 6;12(1):e0169497. doi: 10.1371/journal.pone.0169497. eCollection 2017.


Correction: The BD FACSPresto Point of Care CD4 Test accurately enumerates CD4+ T cell counts.

Bwana P, Vojnov L, Adhiambo M, Akinyi C, Mwende J, Prescott M, Mwau M.

PLoS One. 2016 Dec 9;11(12):e0167667. doi: 10.1371/journal.pone.0167667. eCollection 2016.


Performance Evaluation of the MyT4 Technology for Determining ART Eligibility.

Sitoe N, Macamo R, Meggi B, Tobaiwa O, Loquiha O, Bollinger T, Vojnov L, Jani I.

PLoS One. 2016 Oct 25;11(10):e0165163. doi: 10.1371/journal.pone.0165163. eCollection 2016.


Point-of-Care Viral Load Testing for Sub-Saharan Africa: Informing a Target Product Profile.

Phillips AN, Cambiano V, Nakagawa F, Ford D, Apollo T, Murungu J, Rousseau C, Garnett G, Ehrenkranz P, Bansi-Matharu L, Vojnov L, Katz Z, Peeling R, Revill P.

Open Forum Infect Dis. 2016 Jul 29;3(3):ofw161. eCollection 2016 Sep. Erratum in: Open Forum Infect Dis. 2018 Jan 30;5(1):ofx181.


Evaluation of the Whole-Blood Alere Q NAT Point-of-Care RNA Assay for HIV-1 Viral Load Monitoring in a Primary Health Care Setting in Mozambique.

Jani IV, Meggi B, Vubil A, Sitoe NE, Bhatt N, Tobaiwa O, Quevedo JI, Loquiha O, Lehe JD, Vojnov L, Peter TF.

J Clin Microbiol. 2016 Aug;54(8):2104-8. doi: 10.1128/JCM.00362-16. Epub 2016 Jun 1.


POC CD4 Testing Improves Linkage to HIV Care and Timeliness of ART Initiation in a Public Health Approach: A Systematic Review and Meta-Analysis.

Vojnov L, Markby J, Boeke C, Harris L, Ford N, Peter T.

PLoS One. 2016 May 13;11(5):e0155256. doi: 10.1371/journal.pone.0155256. eCollection 2016. Review.


Use of mobile phone technology to improve the quality of point-of-care testing in a low-resource setting.

Jani IV, Quevedo JI, Tobaiwa O, Bollinger T, Sitoe NE, Chongo P, Vojnov L, Lehe JD, Peter T.

AIDS. 2016 Jan 2;30(1):159-61. doi: 10.1097/QAD.0000000000000907. No abstract available.


The BD FACSPresto Point of Care CD4 Test Accurately Enumerates CD4+ T Cell Counts.

Bwana P, Vojnov L, Adhiambo M, Akinyi C, Mwende J, Prescott M, Mwau M.

PLoS One. 2015 Dec 31;10(12):e0145586. doi: 10.1371/journal.pone.0145586. eCollection 2015. Erratum in: PLoS One. 2016 Dec 9;11(12 ):e0167667.


Reducing mortality in HIV-infected infants and achieving the 90-90-90 target through innovative diagnosis approaches.

Essajee S, Vojnov L, Penazzato M, Jani I, Siberry GK, Fiscus SA, Markby J.

J Int AIDS Soc. 2015 Dec 2;18(Suppl 6):20299. doi: 10.7448/IAS.18.7.20299. eCollection 2015. Review.


Sustainable HIV treatment in Africa through viral-load-informed differentiated care.

Working Group on Modelling of Antiretroviral Therapy Monitoring Strategies in Sub-Saharan Africa, Phillips A, Shroufi A, Vojnov L, Cohn J, Roberts T, Ellman T, Bonner K, Rousseau C, Garnett G, Cambiano V, Nakagawa F, Ford D, Bansi-Matharu L, Miners A, Lundgren JD, Eaton JW, Parkes-Ratanshi R, Katz Z, Maman D, Ford N, Vitoria M, Doherty M, Dowdy D, Nichols B, Murtagh M, Wareham M, Palamountain KM, Chakanyuka Musanhu C, Stevens W, Katzenstein D, Ciaranello A, Barnabas R, Braithwaite RS, Bendavid E, Nathoo KJ, van de Vijver D, Wilson DP, Holmes C, Bershteyn A, Walker S, Raizes E, Jani I, Nelson LJ, Peeling R, Terris-Prestholt F, Murungu J, Mutasa-Apollo T, Hallett TB, Revill P.

Nature. 2015 Dec 3;528(7580):S68-76. doi: 10.1038/nature16046.


A meta-analysis of the performance of the Pima™ CD4 for point of care testing.

Scott LE, Campbell J, Westerman L, Kestens L, Vojnov L, Kohastsu L, Nkengasong J, Peter T, Stevens W.

BMC Med. 2015 Jul 25;13:168. doi: 10.1186/s12916-015-0396-2.


Implementation and Operational Research: Expedited Results Delivery Systems Using GPRS Technology Significantly Reduce Early Infant Diagnosis Test Turnaround Times.

Deo S, Crea L, Quevedo J, Lehe J, Vojnov L, Peter T, Jani I.

J Acquir Immune Defic Syndr. 2015 Sep 1;70(1):e1-4. doi: 10.1097/QAI.0000000000000719.


Technical performance evaluation of the MyT4 point of care technology for CD4+ T cell enumeration.

Mwau M, Kadima S, Mwende J, Adhiambo M, Akinyi C, Prescott M, Lusike J, Hungu J, Vojnov L.

PLoS One. 2014 Sep 17;9(9):e107410. doi: 10.1371/journal.pone.0107410. eCollection 2014.


Accurate early infant HIV diagnosis in primary health clinics using a point-of-care nucleic acid test.

Jani IV, Meggi B, Mabunda N, Vubil A, Sitoe NE, Tobaiwa O, Quevedo JI, Lehe JD, Loquiha O, Vojnov L, Peter TF.

J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):e1-4. doi: 10.1097/QAI.0000000000000250.


Improved access to early infant diagnosis is a critical part of a child-centric prevention of mother-to-child transmission agenda.

Ghadrshenas A, Ben Amor Y, Chang J, Dale H, Sherman G, Vojnov L, Young P, Yogev R; Child Survival Working Group of the Interagency Task Team on the Prevention and Treatment of HIV infection in Pregnant Women, Mothers and Children.

AIDS. 2013 Nov;27 Suppl 2:S197-205. doi: 10.1097/QAD.0000000000000104. Review.


The majority of freshly sorted simian immunodeficiency virus (SIV)-specific CD8(+) T cells cannot suppress viral replication in SIV-infected macrophages.

Vojnov L, Martins MA, Bean AT, Veloso de Santana MG, Sacha JB, Wilson NA, Bonaldo MC, Galler R, Stevenson M, Watkins DI.

J Virol. 2012 Apr;86(8):4682-7. doi: 10.1128/JVI.06324-11. Epub 2012 Feb 8.


GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo.

Vojnov L, Martins MA, Almeida JR, Ende Z, Rakasz EG, Reynolds MR, Leon EJ, Weisgrau KL, Burwitz BJ, Folkvord JM, de Santana MG, Neves PC, Connick E, Skinner PJ, Gostick E, O'Connor DH, Wilson NA, Bonaldo MC, Galler R, Price DA, Douek DC, Watkins DI.

PLoS One. 2011;6(8):e23515. doi: 10.1371/journal.pone.0023515. Epub 2011 Aug 26.


DNA/Ad5 vaccination with SIV epitopes induced epitope-specific CD4⁺ T cells, but few subdominant epitope-specific CD8⁺ T cells.

Vojnov L, Bean AT, Peterson EJ, Chiuchiolo MJ, Sacha JB, Denes FS, Sandor M, Fuller DH, Fuller JT, Parks CL, McDermott AB, Wilson NA, Watkins DI.

Vaccine. 2011 Oct 6;29(43):7483-90. doi: 10.1016/j.vaccine.2011.07.048. Epub 2011 Aug 10.


Recombinant yellow fever vaccine virus 17D expressing simian immunodeficiency virus SIVmac239 gag induces SIV-specific CD8+ T-cell responses in rhesus macaques.

Bonaldo MC, Martins MA, Rudersdorf R, Mudd PA, Sacha JB, Piaskowski SM, Costa Neves PC, Veloso de Santana MG, Vojnov L, Capuano S 3rd, Rakasz EG, Wilson NA, Fulkerson J, Sadoff JC, Watkins DI, Galler R.

J Virol. 2010 Apr;84(7):3699-706. doi: 10.1128/JVI.02255-09. Epub 2010 Jan 20.


Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.

Vojnov L, Reed JS, Weisgrau KL, Rakasz EG, Loffredo JT, Piaskowski SM, Sacha JB, Kolar HL, Wilson NA, Johnson RP, Watkins DI.

J Virol. 2010 Jan;84(2):753-64. doi: 10.1128/JVI.01596-09. Epub 2009 Nov 4.


Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation.

Sacha JB, Chung C, Reed J, Jonas AK, Bean AT, Spencer SP, Lee W, Vojnov L, Rudersdorf R, Friedrich TC, Wilson NA, Lifson JD, Watkins DI.

J Virol. 2007 Nov;81(21):11703-12. Epub 2007 Aug 15.


Consequences of cytotoxic T-lymphocyte escape: common escape mutations in simian immunodeficiency virus are poorly recognized in naive hosts.

Friedrich TC, McDermott AB, Reynolds MR, Piaskowski S, Fuenger S, De Souza IP, Rudersdorf R, Cullen C, Yant LJ, Vojnov L, Stephany J, Martin S, O'Connor DH, Wilson N, Watkins DI.

J Virol. 2004 Sep;78(18):10064-73.


Reversion of CTL escape-variant immunodeficiency viruses in vivo.

Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI.

Nat Med. 2004 Mar;10(3):275-81. Epub 2004 Feb 15.


Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response.

Friedrich TC, Frye CA, Yant LJ, O'Connor DH, Kriewaldt NA, Benson M, Vojnov L, Dodds EJ, Cullen C, Rudersdorf R, Hughes AL, Wilson N, Watkins DI.

J Virol. 2004 Mar;78(5):2581-5.

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