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Items: 1 to 50 of 152

1.

miRNA expression profiles and molecular networks in resting and LPS-activated BV-2 microglia-Effect of cannabinoids.

Juknat A, Gao F, Coppola G, Vogel Z, Kozela E.

PLoS One. 2019 Feb 11;14(2):e0212039. doi: 10.1371/journal.pone.0212039. eCollection 2019.

2.

Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid.

Kozela E, Juknat A, Vogel Z.

Int J Mol Sci. 2017 Jul 31;18(8). pii: E1669. doi: 10.3390/ijms18081669. Review.

3.

Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells.

Kozela E, Juknat A, Gao F, Kaushansky N, Coppola G, Vogel Z.

J Neuroinflammation. 2016 Jun 3;13(1):136. doi: 10.1186/s12974-016-0603-x.

4.

Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells.

Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z.

J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):289-96. doi: 10.1515/jbcpp-2015-0071.

5.

HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells.

Kozela E, Haj C, Hanuš L, Chourasia M, Shurki A, Juknat A, Kaushansky N, Mechoulam R, Vogel Z.

Chem Biol Drug Des. 2016 Jan;87(1):143-53. doi: 10.1111/cbdd.12637. Epub 2015 Sep 16.

PMID:
26259697
6.

Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells.

Kozela E, Juknat A, Kaushansky N, Ben-Nun A, Coppola G, Vogel Z.

J Neuroinflammation. 2015 Mar 15;12:52. doi: 10.1186/s12974-015-0273-0.

7.

Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death.

Rimmerman N, Ben-Hail D, Porat Z, Juknat A, Kozela E, Daniels MP, Connelly PS, Leishman E, Bradshaw HB, Shoshan-Barmatz V, Vogel Z.

Cell Death Dis. 2013 Dec 5;4:e949. doi: 10.1038/cddis.2013.471.

8.

Cannabinoids decrease the th17 inflammatory autoimmune phenotype.

Kozela E, Juknat A, Kaushansky N, Rimmerman N, Ben-Nun A, Vogel Z.

J Neuroimmune Pharmacol. 2013 Dec;8(5):1265-76. doi: 10.1007/s11481-013-9493-1. Epub 2013 Jul 28.

PMID:
23892791
9.

Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells.

Juknat A, Pietr M, Kozela E, Rimmerman N, Levy R, Gao F, Coppola G, Geschwind D, Vogel Z.

PLoS One. 2013 Apr 24;8(4):e61462. doi: 10.1371/journal.pone.0061462. Print 2013.

10.

Cannabidiol affects the expression of genes involved in zinc homeostasis in BV-2 microglial cells.

Juknat A, Rimmerman N, Levy R, Vogel Z, Kozela E.

Neurochem Int. 2012 Nov;61(6):923-30. doi: 10.1016/j.neuint.2011.12.002. Epub 2011 Dec 9.

PMID:
22178458
11.

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.

Juknat A, Pietr M, Kozela E, Rimmerman N, Levy R, Coppola G, Geschwind D, Vogel Z.

Br J Pharmacol. 2012 Apr;165(8):2512-28. doi: 10.1111/j.1476-5381.2011.01461.x.

12.

The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells.

Rimmerman N, Juknat A, Kozela E, Levy R, Bradshaw HB, Vogel Z.

Cell Mol Neurobiol. 2011 Aug;31(6):921-30. doi: 10.1007/s10571-011-9692-3. Epub 2011 Apr 30.

PMID:
21533611
13.

Compartmentalization of endocannabinoids into lipid rafts in a microglial cell line devoid of caveolin-1.

Rimmerman N, Bradshaw HB, Kozela E, Levy R, Juknat A, Vogel Z.

Br J Pharmacol. 2012 Apr;165(8):2436-49. doi: 10.1111/j.1476-5381.2011.01380.x.

14.

Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice.

Kozela E, Lev N, Kaushansky N, Eilam R, Rimmerman N, Levy R, Ben-Nun A, Juknat A, Vogel Z.

Br J Pharmacol. 2011 Aug;163(7):1507-19. doi: 10.1111/j.1476-5381.2011.01379.x.

15.

Cannabinoids reveal separate controls for whisking amplitude and timing in rats.

Pietr MD, Knutsen PM, Shore DI, Ahissar E, Vogel Z.

J Neurophysiol. 2010 Nov;104(5):2532-42. doi: 10.1152/jn.01039.2009. Epub 2010 Sep 15.

16.

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.

McHugh D, Hu SS, Rimmerman N, Juknat A, Vogel Z, Walker JM, Bradshaw HB.

BMC Neurosci. 2010 Mar 26;11:44. doi: 10.1186/1471-2202-11-44.

17.

Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells.

Kozela E, Pietr M, Juknat A, Rimmerman N, Levy R, Vogel Z.

J Biol Chem. 2010 Jan 15;285(3):1616-26. doi: 10.1074/jbc.M109.069294. Epub 2009 Nov 12.

18.

Differential changes in GPR55 during microglial cell activation.

Pietr M, Kozela E, Levy R, Rimmerman N, Lin YH, Stella N, Vogel Z, Juknat A.

FEBS Lett. 2009 Jun 18;583(12):2071-6. doi: 10.1016/j.febslet.2009.05.028. Epub 2009 May 22.

19.

Hippocampal interneurons co-express transcripts encoding the alpha7 nicotinic receptor subunit and the cannabinoid receptor 1.

Morales M, Hein K, Vogel Z.

Neuroscience. 2008 Mar 3;152(1):70-81. doi: 10.1016/j.neuroscience.2007.12.019.

20.

Anandamide protects from low serum-induced apoptosis via its degradation to ethanolamine.

Matas D, Juknat A, Pietr M, Klin Y, Vogel Z.

J Biol Chem. 2007 Mar 16;282(11):7885-92. Epub 2007 Jan 16.

21.

Inhibition of AC-II activity following chronic agonist exposure is modulated by phosphorylation.

Schallmach E, Steiner D, Vogel Z.

J Mol Neurosci. 2006;29(2):115-22.

PMID:
16954601
22.

Adenylyl cyclase type II activity is regulated by two different mechanisms: implications for acute and chronic opioid exposure.

Schallmach E, Steiner D, Vogel Z.

Neuropharmacology. 2006 Jun;50(8):998-1005. Epub 2006 Mar 20.

PMID:
16545401
23.

Chronic exposure to Delta9-tetrahydrocannabinol downregulates oxytocin and oxytocin-associated neurophysin in specific brain areas.

Butovsky E, Juknat A, Elbaz J, Shabat-Simon M, Eilam R, Zangen A, Altstein M, Vogel Z.

Mol Cell Neurosci. 2006 Apr;31(4):795-804. Epub 2006 Mar 2.

PMID:
16513365
24.

Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production.

Shmist YA, Goncharov I, Eichler M, Shneyvays V, Isaac A, Vogel Z, Shainberg A.

Mol Cell Biochem. 2006 Feb;283(1-2):75-83.

PMID:
16444588
25.

Inhibition and superactivation of the calcium-stimulated isoforms of adenylyl cyclase: role of Gbetagamma dimers.

Steiner D, Avidor-Reiss T, Schallmach E, Saya D, Vogel Z.

J Mol Neurosci. 2005;27(2):195-203.

PMID:
16186630
26.

Delta9-tetrahydrocannabinol increases C6 glioma cell death produced by oxidative stress.

Goncharov I, Weiner L, Vogel Z.

Neuroscience. 2005;134(2):567-74.

PMID:
15975726
27.

Adenylyl cyclase type-VIII activity is regulated by G(betagamma) subunits.

Steiner D, Saya D, Schallmach E, Simonds WF, Vogel Z.

Cell Signal. 2006 Jan;18(1):62-8. Epub 2005 May 31.

PMID:
15925485
28.

In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol.

Butovsky E, Juknat A, Goncharov I, Elbaz J, Eilam R, Zangen A, Vogel Z.

J Neurochem. 2005 May;93(4):802-11.

29.

Regulation of adenylate cyclase type VIII splice variants by acute and chronic Gi/o-coupled receptor activation.

Steiner D, Avidor-Reiss T, Schallmach E, Butovsky E, Lev N, Vogel Z.

Biochem J. 2005 Mar 1;386(Pt 2):341-8.

30.

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.

Di Marzo V, Melck D, Orlando P, Bisogno T, Zagoory O, Bifulco M, Vogel Z, De Petrocellis L.

Biochem J. 2001 Aug 15;358(Pt 1):249-55.

31.

D2/D3 dopamine receptor heterodimers exhibit unique functional properties.

Scarselli M, Novi F, Schallmach E, Lin R, Baragli A, Colzi A, Griffon N, Corsini GU, Sokoloff P, Levenson R, Vogel Z, Maggio R.

J Biol Chem. 2001 Aug 10;276(32):30308-14. Epub 2001 May 23.

32.

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor.

Hanus L, Abu-Lafi S, Fride E, Breuer A, Vogel Z, Shalev DE, Kustanovich I, Mechoulam R.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3662-5. Epub 2001 Mar 20.

33.

Functional role of tryptophan residues in the fourth transmembrane domain of the CB(2) cannabinoid receptor.

Rhee MH, Nevo I, Bayewitch ML, Zagoory O, Vogel Z.

J Neurochem. 2000 Dec;75(6):2485-91.

35.

Morphine-related metabolites differentially activate adenylyl cyclase isozymes after acute and chronic administration.

Eckhardt K, Nevo I, Levy R, Mikus G, Eichelbaum M, Vogel Z.

FEBS Lett. 2000 Mar 31;470(3):309-14.

37.

Differential superactivation of adenylyl cyclase isozymes after chronic activation of the CB(1) cannabinoid receptor.

Rhee MH, Nevo I, Avidor-Reiss T, Levy R, Vogel Z.

Mol Pharmacol. 2000 Apr;57(4):746-52.

PMID:
10727521
38.

Acute and chronic activation of the mu-opioid receptor with the endogenous ligand endomorphin differentially regulates adenylyl cyclase isozymes.

Nevo I, Avidor-Reiss T, Levy R, Bayewitch M, Vogel Z.

Neuropharmacology. 2000 Jan 28;39(3):364-71.

PMID:
10698002
39.

Role of the highly conserved Asp-Arg-Tyr motif in signal transduction of the CB2 cannabinoid receptor.

Rhee MH, Nevo I, Levy R, Vogel Z.

FEBS Lett. 2000 Jan 28;466(2-3):300-4.

40.

Adenylyl cyclase interaction with the D2 dopamine receptor family; differential coupling to Gi, Gz, and Gs.

Obadiah J, Avidor-Reiss T, Fishburn CS, Carmon S, Bayewitch M, Vogel Z, Fuchs S, Levavi-Sivan B.

Cell Mol Neurobiol. 1999 Oct;19(5):653-64.

PMID:
10384262
41.

Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes.

Rhee MH, Bayewitch M, Avidor-Reiss T, Levy R, Vogel Z.

J Neurochem. 1998 Oct;71(4):1525-34.

42.

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity.

Ben-Shabat S, Fride E, Sheskin T, Tamiri T, Rhee MH, Vogel Z, Bisogno T, De Petrocellis L, Di Marzo V, Mechoulam R.

Eur J Pharmacol. 1998 Jul 17;353(1):23-31.

PMID:
9721036
43.

Inhibition of adenylyl cyclase isoforms V and VI by various Gbetagamma subunits.

Bayewitch ML, Avidor-Reiss T, Levy R, Pfeuffer T, Nevo I, Simonds WF, Vogel Z.

FASEB J. 1998 Aug;12(11):1019-25.

PMID:
9707174
44.

Interaction of agonist peptide [3H]Tyr-D-Ala-Phe-Phe-NH2 with mu-opioid receptor in rat brain and CHO-mu/1 cell line.

Spetea M, Otvös F, Tóth G, Nguyen TM, Schiller PW, Vogel Z, Borsodi A.

Peptides. 1998;19(6):1091-8.

PMID:
9700760
45.

Regulation of adenylyl cyclase isozymes on acute and chronic activation of inhibitory receptors.

Nevo I, Avidor-Reiss T, Levy R, Bayewitch M, Heldman E, Vogel Z.

Mol Pharmacol. 1998 Aug;54(2):419-26.

PMID:
9687584
46.

Nociceptive stimulus induces release of endogenous beta-endorphin in the rat brain.

Zangen A, Herzberg U, Vogel Z, Yadid G.

Neuroscience. 1998 Aug;85(3):659-62.

PMID:
9639262
47.

Opioid modulation of extracellular signal-regulated protein kinase activity is ras-dependent and involves Gbetagamma subunits.

Belcheva MM, Vogel Z, Ignatova E, Avidor-Reiss T, Zippel R, Levy R, Young EC, Barg J, Coscia CJ.

J Neurochem. 1998 Feb;70(2):635-45.

48.

Differential modulation of adenylyl cyclases I and II by various G beta subunits.

Bayewitch ML, Avidor-Reiss T, Levy R, Pfeuffer T, Nevo I, Simonds WF, Vogel Z.

J Biol Chem. 1998 Jan 23;273(4):2273-6.

49.

Acupuncture and the opioid system: implications in management of migraine.

Pintov S, Lahat E, Alstein M, Vogel Z, Barg J.

Pediatr Neurol. 1997 Sep;17(2):129-33.

PMID:
9367292
50.

Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase.

Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanus L, Breuer A, Mechoulam R.

J Med Chem. 1997 Sep 26;40(20):3228-33.

PMID:
9379442

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