Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 207


Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37.

Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED.

Am J Respir Cell Mol Biol. 2019 Sep 23. doi: 10.1165/rcmb.2018-0278OC. [Epub ahead of print]


High-throughput screening for phosphatidylserine decarboxylase inhibitors using a distyrylbenzene-bis-aldehyde (DSB-3)-based fluorescence assay.

Hendricson A, Umlauf S, Choi JY, Thekkiniath J, Surovtseva YV, Fuller KK, Reynolds TB, Voelker DR, Ben Mamoun C.

J Biol Chem. 2019 Aug 9;294(32):12146-12156. doi: 10.1074/jbc.RA119.007766. Epub 2019 Jun 21.


Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations.

Everman JL, Sajuthi S, Saef B, Rios C, Stoner AM, Numata M, Hu D, Eng C, Oh S, Rodriguez-Santana J, Vladar EK, Voelker DR, Burchard EG, Seibold MA.

J Allergy Clin Immunol. 2019 Oct;144(4):962-971. doi: 10.1016/j.jaci.2019.01.052. Epub 2019 Mar 29.


Phospholipid regulation of innate immunity and respiratory viral infection.

Voelker DR, Numata M.

J Biol Chem. 2019 Mar 22;294(12):4282-4289. doi: 10.1074/jbc.AW118.003229. Epub 2019 Feb 7. Review.


Interaction of two antitumor peptides with membrane lipids - Influence of phosphatidylserine and cholesterol on specificity for melanoma cells.

Wodlej C, Riedl S, Rinner B, Leber R, Drechsler C, Voelker DR, Choi JY, Lohner K, Zweytick D.

PLoS One. 2019 Jan 25;14(1):e0211187. doi: 10.1371/journal.pone.0211187. eCollection 2019.


Role of phospholipid synthesis in the development and differentiation of malaria parasites in the blood.

Kilian N, Choi JY, Voelker DR, Ben Mamoun C.

J Biol Chem. 2018 Nov 9;293(45):17308-17316. doi: 10.1074/jbc.R118.003213. Epub 2018 Oct 4. Review.


Preparation of Asymmetric Liposomes Using a Phosphatidylserine Decarboxylase.

Drechsler C, Markones M, Choi JY, Frieling N, Fiedler S, Voelker DR, Schubert R, Heerklotz H.

Biophys J. 2018 Oct 16;115(8):1509-1517. doi: 10.1016/j.bpj.2018.08.036. Epub 2018 Sep 1.


Identification of a Novel Inhibitor of Human Rhinovirus Replication and Inflammation in Airway Epithelial Cells.

Yang Z, Bochkov YA, Voelker DR, Foster MW, Que LG.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):58-67. doi: 10.1165/rcmb.2018-0058OC.


The Emerging Roles of Surfactant Protein-A in Asthma.

Dy ABC, Tanyaratsrisakul S, Voelker DR, Ledford JG.

J Clin Cell Immunol. 2018;9(4). pii: 553. doi: 10.4172/2155-9899.1000553. Epub 2018 Jul 16.


A novel fluorescence assay for measuring phosphatidylserine decarboxylase catalysis.

Choi JY, Surovtseva YV, Van Sickle SM, Kumpf J, Bunz UHF, Ben Mamoun C, Voelker DR.

J Biol Chem. 2018 Feb 2;293(5):1493-1503. doi: 10.1074/jbc.RA117.000525. Epub 2017 Dec 15.


The antimalarial activity of the pantothenamide α-PanAm is via inhibition of pantothenate phosphorylation.

Chiu JE, Thekkiniath J, Choi JY, Perrin BA, Lawres L, Plummer M, Virji AZ, Abraham A, Toh JY, Zandt MV, Aly ASI, Voelker DR, Mamoun CB.

Sci Rep. 2017 Oct 27;7(1):14234. doi: 10.1038/s41598-017-14074-9.


Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei.

Farine L, Jelk J, Choi JY, Voelker DR, Nunes J, Smith TK, Bütikofer P.

Mol Microbiol. 2017 May;104(3):412-427. doi: 10.1111/mmi.13637. Epub 2017 Mar 2.


Tandem mass spectrometry of novel ether-linked phospholipid analogs of anionic pulmonary surfactant phospholipids.

Fickes R, Voelker DR, Berry KZ, Murphy RC.

Rapid Commun Mass Spectrom. 2016 Dec 30;30(24):2601-2606. doi: 10.1002/rcm.7750.


Structural analogs of pulmonary surfactant phosphatidylglycerol inhibit toll-like receptor 2 and 4 signaling.

Kandasamy P, Numata M, Berry KZ, Fickes R, Leslie CC, Murphy RC, Voelker DR.

J Lipid Res. 2016 Jun;57(6):993-1005. doi: 10.1194/jlr.M065201. Epub 2016 Apr 19.


Genetic Variation in Surfactant Protein-A2 Results in Altered Regulation of Eosinophil Activities and Enhanced Eosinophilia in Patients with Asthma.

Ledford JG, Addison KJ, Francisco D, Foster MW, Voelker DR, Que LG, Kraft M.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S101. doi: 10.1513/AnnalsATS.201508-520MG. No abstract available.


Characterization of Plasmodium phosphatidylserine decarboxylase expressed in yeast and application for inhibitor screening.

Choi JY, Kumar V, Pachikara N, Garg A, Lawres L, Toh JY, Voelker DR, Ben Mamoun C.

Mol Microbiol. 2016 Mar;99(6):999-1014. doi: 10.1111/mmi.13280. Epub 2015 Dec 22.


Correction: SP-A Preserves Airway Homeostasis during Mycoplasma pneumoniae Infection in Mice.

Ledford JG, Goto H, Potts EN, Degan S, Wei Chu H, Voelker DR, Sunday ME, Cianciolo GJ, Foster WM, Kraft M, Wright JR.

J Immunol. 2015 Sep 15;195(6):2917-8. doi: 10.4049/jimmunol.1501597. No abstract available.


Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses.

Ledford JG, Voelker DR, Addison KJ, Wang Y, Nikam VS, Degan S, Kandasamy P, Tanyaratsrisakul S, Fischer BM, Kraft M, Hollingsworth JW.

J Immunol. 2015 Jun 15;194(12):6123-32. doi: 10.4049/jimmunol.1500104. Epub 2015 May 8.


Structure, function and inhibition of the phosphoethanolamine methyltransferases of the human malaria parasites Plasmodium vivax and Plasmodium knowlesi.

Garg A, Lukk T, Kumar V, Choi JY, Augagneur Y, Voelker DR, Nair S, Ben Mamoun C.

Sci Rep. 2015 Mar 12;5:9064. doi: 10.1038/srep09064.



Choi JY, Duraisingh MT, Marti M, Ben Mamoun C, Voelker DR.

J Biol Chem. 2015 Apr 24;290(17):10972-80. doi: 10.1074/jbc.M115.642413. Epub 2015 Feb 26.


Phosphatidylinositol inhibits respiratory syncytial virus infection.

Numata M, Kandasamy P, Nagashima Y, Fickes R, Murphy RC, Voelker DR.

J Lipid Res. 2015 Mar;56(3):578-87. doi: 10.1194/jlr.M055723. Epub 2015 Jan 5.


Transport of phosphatidylserine from the endoplasmic reticulum to the site of phosphatidylserine decarboxylase2 in yeast.

Kannan M, Riekhof WR, Voelker DR.

Traffic. 2015 Feb;16(2):123-34. doi: 10.1111/tra.12236. Epub 2014 Dec 11. Review.


Structural characterization of the pulmonary innate immune protein SPLUNC1 and identification of lipid ligands.

Ning F, Wang C, Berry KZ, Kandasamy P, Liu H, Murphy RC, Voelker DR, Nho CW, Pan CH, Dai S, Niu L, Chu HW, Zhang G.

FASEB J. 2014 Dec;28(12):5349-60. doi: 10.1096/fj.14-259291. Epub 2014 Sep 15.


Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.

Foster MW, Thompson JW, Ledford JG, Dubois LG, Hollingsworth JW, Francisco D, Tanyaratsrisakul S, Voelker DR, Kraft M, Moseley MA, Foster WM.

J Proteome Res. 2014 Aug 1;13(8):3722-32. doi: 10.1021/pr500307f. Epub 2014 Jul 15.


Phosphate starvation in fungi induces the replacement of phosphatidylcholine with the phosphorus-free betaine lipid diacylglyceryl-N,N,N-trimethylhomoserine.

Riekhof WR, Naik S, Bertrand H, Benning C, Voelker DR.

Eukaryot Cell. 2014 Jun;13(6):749-57. doi: 10.1128/EC.00004-14. Epub 2014 Apr 11.


Measurement of lysophospholipid acyltransferase activities using substrate competition.

Martin SA, Gijón MA, Voelker DR, Murphy RC.

J Lipid Res. 2014 Apr;55(4):782-91. doi: 10.1194/jlr.D044636. Epub 2014 Feb 21.


Phosphatidylethanolamine synthesis in the parasite mitochondrion is required for efficient growth but dispensable for survival of Toxoplasma gondii.

Hartmann A, Hellmund M, Lucius R, Voelker DR, Gupta N.

J Biol Chem. 2014 Mar 7;289(10):6809-24. doi: 10.1074/jbc.M113.509406. Epub 2014 Jan 15.


An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.

Riekhof WR, Wu WI, Jones JL, Nikrad M, Chan MM, Loewen CJ, Voelker DR.

J Biol Chem. 2014 Feb 28;289(9):5809-19. doi: 10.1074/jbc.M113.518217. Epub 2013 Dec 23.


Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission.

Bobenchik AM, Witola WH, Augagneur Y, Nic Lochlainn L, Garg A, Pachikara N, Choi JY, Zhao YO, Usmani-Brown S, Lee A, Adjalley SH, Samanta S, Fidock DA, Voelker DR, Fikrig E, Ben Mamoun C.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18262-7. doi: 10.1073/pnas.1313965110. Epub 2013 Oct 21.


Phosphatidylglycerol provides short-term prophylaxis against respiratory syncytial virus infection.

Numata M, Nagashima Y, Moore ML, Berry KZ, Chan M, Kandasamy P, Peebles RS Jr, Murphy RC, Voelker DR.

J Lipid Res. 2013 Aug;54(8):2133-43. doi: 10.1194/jlr.M037077. Epub 2013 Jun 6.


Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung.

Numata M, Grinkova YV, Mitchell JR, Chu HW, Sligar SG, Voelker DR.

Int J Nanomedicine. 2013;8:1417-27. doi: 10.2147/IJN.S39888. Epub 2013 Apr 15.


Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages.

Bai X, Feldman NE, Chmura K, Ovrutsky AR, Su WL, Griffin L, Pyeon D, McGibney MT, Strand MJ, Numata M, Murakami S, Gaido L, Honda JR, Kinney WH, Oberley-Deegan RE, Voelker DR, Ordway DJ, Chan ED.

PLoS One. 2013 Apr 25;8(4):e61925. doi: 10.1371/journal.pone.0061925. Print 2013.


Anionic pulmonary surfactant lipid regulation of innate immunity.

Numata M, Kandasamy P, Voelker DR.

Expert Rev Respir Med. 2012 Jun;6(3):243-6. doi: 10.1586/ers.12.21. No abstract available.


The obligate intracellular parasite Toxoplasma gondii secretes a soluble phosphatidylserine decarboxylase.

Gupta N, Hartmann A, Lucius R, Voelker DR.

J Biol Chem. 2012 Jun 29;287(27):22938-47. doi: 10.1074/jbc.M112.373639. Epub 2012 May 4.


Surfactant protein D (Sp-D) binds to membrane-proximal domain (D3) of signal regulatory protein α (SIRPα), a site distant from binding domain of CD47, while also binding to analogous region on signal regulatory protein β (SIRPβ).

Fournier B, Andargachew R, Robin AZ, Laur O, Voelker DR, Lee WY, Weber D, Parkos CA.

J Biol Chem. 2012 Jun 1;287(23):19386-98. doi: 10.1074/jbc.M111.324533. Epub 2012 Apr 16.


Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance.

Nguyen TT, Lewandowska A, Choi JY, Markgraf DF, Junker M, Bilgin M, Ejsing CS, Voelker DR, Rapoport TA, Shaw JM.

Traffic. 2012 Jun;13(6):880-90. doi: 10.1111/j.1600-0854.2012.01352.x. Epub 2012 Apr 8.


Infection of human alveolar macrophages by human coronavirus strain 229E.

Funk CJ, Wang J, Ito Y, Travanty EA, Voelker DR, Holmes KV, Mason RJ.

J Gen Virol. 2012 Mar;93(Pt 3):494-503. doi: 10.1099/vir.0.038414-0. Epub 2011 Nov 16.


Identification of gene encoding Plasmodium knowlesi phosphatidylserine decarboxylase by genetic complementation in yeast and characterization of in vitro maturation of encoded enzyme.

Choi JY, Augagneur Y, Ben Mamoun C, Voelker DR.

J Biol Chem. 2012 Jan 2;287(1):222-32. doi: 10.1074/jbc.M111.313676. Epub 2011 Nov 4.


Phosphatidylglycerol suppresses influenza A virus infection.

Numata M, Kandasamy P, Nagashima Y, Posey J, Hartshorn K, Woodland D, Voelker DR.

Am J Respir Cell Mol Biol. 2012 Apr;46(4):479-87. doi: 10.1165/rcmb.2011-0194OC. Epub 2011 Nov 3.


Surfactant protein A is defective in abrogating inflammation in asthma.

Wang Y, Voelker DR, Lugogo NL, Wang G, Floros J, Ingram JL, Chu HW, Church TD, Kandasamy P, Fertel D, Wright JR, Kraft M.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L598-606. doi: 10.1152/ajplung.00381.2010. Epub 2011 Jul 22. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2012 Feb; 302 (3):L360.


Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models.

Shang S, Ordway D, Henao-Tamayo M, Bai X, Oberley-Deegan R, Shanley C, Orme IM, Case S, Minor M, Ackart D, Hascall-Dove L, Ovrutsky AR, Kandasamy P, Voelker DR, Lambert C, Freed BM, Iseman MD, Basaraba RJ, Chan ED.

J Infect Dis. 2011 May 1;203(9):1240-8. doi: 10.1093/infdis/jir009. Epub 2011 Feb 28.


Enhanced proliferation of primary rat type II pneumocytes by Jaagsiekte sheep retrovirus envelope protein.

Johnson C, Jahid S, Voelker DR, Fan H.

Virology. 2011 Apr 10;412(2):349-56. doi: 10.1016/j.virol.2011.01.022. Epub 2011 Feb 12.


FXYD proteins stabilize Na,K-ATPase: amplification of specific phosphatidylserine-protein interactions.

Mishra NK, Peleg Y, Cirri E, Belogus T, Lifshitz Y, Voelker DR, Apell HJ, Garty H, Karlish SJ.

J Biol Chem. 2011 Mar 18;286(11):9699-712. doi: 10.1074/jbc.M110.184234. Epub 2011 Jan 12.


Making heads or tails of phospholipids in mitochondria.

Osman C, Voelker DR, Langer T.

J Cell Biol. 2011 Jan 10;192(1):7-16. doi: 10.1083/jcb.201006159. Review.


Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages.

Kandasamy P, Zarini S, Chan ED, Leslie CC, Murphy RC, Voelker DR.

J Biol Chem. 2011 Mar 11;286(10):7841-53. doi: 10.1074/jbc.M110.170241. Epub 2011 Jan 4.


Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease.

Moré JM, Voelker DR, Silveira LJ, Edwards MG, Chan ED, Bowler RP.

BMC Pulm Med. 2010 Oct 25;10:53. doi: 10.1186/1471-2466-10-53.


Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2.

Brechbuhl HM, Gould N, Kachadourian R, Riekhof WR, Voelker DR, Day BJ.

J Biol Chem. 2010 May 28;285(22):16582-7. doi: 10.1074/jbc.M109.090506. Epub 2010 Mar 23.


Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay.

Bobenchik AM, Choi JY, Mishra A, Rujan IN, Hao B, Voelker DR, Hoch JC, Mamoun CB.

BMC Biochem. 2010 Jan 19;11:4. doi: 10.1186/1471-2091-11-4.


Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection.

Numata M, Chu HW, Dakhama A, Voelker DR.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):320-5. doi: 10.1073/pnas.0909361107. Epub 2009 Dec 22.


Altered lung surfactant system in a Rab38-deficient rat model of Hermansky-Pudlak syndrome.

Osanai K, Higuchi J, Oikawa R, Kobayashi M, Tsuchihara K, Iguchi M, Huang J, Voelker DR, Toga H.

Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L243-51. doi: 10.1152/ajplung.00242.2009. Epub 2009 Nov 6.

Supplemental Content

Loading ...
Support Center