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Items: 1 to 50 of 393

1.

Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation.

Tian W, Jiang X, Sung YK, Shuffle E, Wu TH, Kao PN, Tu AB, Dorfmüller P, Cao A, Wang L, Peng G, Kim Y, Zhang P, Chappell J, Pasupneti S, Dahms P, Maguire P, Chaib H, Zamanian R, Peters-Golden M, Snyder MP, Voelkel NF, Humbert M, Rabinovitch M, Nicolls MR.

Circulation. 2019 Oct 22;140(17):1409-1425. doi: 10.1161/CIRCULATIONAHA.119.040629. Epub 2019 Aug 29.

PMID:
31462075
2.

Role of the Aryl Hydrocarbon Receptor/ARNT/Cytochrome P450 System in Pulmonary Vascular Diseases.

Kwapiszewska G, Johansen AKZ, Gomez-Arroyo J, Voelkel NF.

Circ Res. 2019 Jul 19;125(3):356-366. doi: 10.1161/CIRCRESAHA.119.315054. Epub 2019 Jun 26.

PMID:
31242807
3.

Restrictive atrial communication in right and left heart failure.

Bauer A, Esmaeili A, deRosa R, Voelkel NF, Schranz D.

Transl Pediatr. 2019 Apr;8(2):133-139. doi: 10.21037/tp.2019.04.03. Review.

4.

Is Myocardial Fibrosis Impairing Right Heart Function?

Bogaard HJ, Voelkel NF.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1458-1459. doi: 10.1164/rccm.201812-2307ED. No abstract available.

5.

Endothelial cells from pulmonary endarterectomy specimens possess a high angiogenic potential and express high levels of hepatocyte growth factor.

Naito A, Sakao S, Lang IM, Voelkel NF, Jujo T, Ishida K, Sugiura T, Matsumiya G, Yoshino I, Tanabe N, Tatsumi K.

BMC Pulm Med. 2018 Dec 29;18(1):197. doi: 10.1186/s12890-018-0769-3.

6.

Drug abuse and HIV-related pulmonary hypertension: double hit injury.

Harter ZJ, Agarwal S, Dalvi P, Voelkel NF, Dhillon NK.

AIDS. 2018 Nov 28;32(18):2651-2667. doi: 10.1097/QAD.0000000000002030.

PMID:
30234598
7.

Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.

Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, Ventetuolo CE, Vieillard-Baron A, Voelkel NF, Vonk-Noordegraaf A, Hassoun PM; American Thoracic Society Assembly on Pulmonary Circulation.

Am J Respir Crit Care Med. 2018 Aug 15;198(4):e15-e43. doi: 10.1164/rccm.201806-1160ST.

PMID:
30109950
8.

The Light at the End of the Long Pulmonary Hypertension Tunnel Brightens.

Voelkel NF, Newman JH.

Am J Respir Crit Care Med. 2018 Sep 15;198(6):818-820. doi: 10.1164/rccm.201802-0325LE. No abstract available.

PMID:
29944843
9.

Creation of a restrictive atrial communication in pulmonary arterial hypertension (PAH): effective palliation of syncope and end-stage heart failure.

Bauer A, Khalil M, Schmidt D, Bauer J, Esmaeili A, Apitz C, Voelkel NF, Schranz D.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018776518. doi: 10.1177/2045894018776518. Epub 2018 Apr 25.

10.

Creation of a restrictive atrial communication in heart failure with preserved and mid-range ejection fraction: effective palliation of left atrial hypertension and pulmonary congestion.

Bauer A, Khalil M, Lüdemann M, Bauer J, Esmaeili A, De-Rosa R, Voelkel NF, Akintuerk H, Schranz D.

Clin Res Cardiol. 2018 Sep;107(9):845-857. doi: 10.1007/s00392-018-1255-x. Epub 2018 Apr 16.

PMID:
29663123
11.

Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.

Tamosiuniene R, Manouvakhova O, Mesange P, Saito T, Qian J, Sanyal M, Lin YC, Nguyen LP, Luria A, Tu AB, Sante JM, Rabinovitch M, Fitzgerald DJ, Graham BB, Habtezion A, Voelkel NF, Aurelian L, Nicolls MR.

Circ Res. 2018 Jun 8;122(12):1689-1702. doi: 10.1161/CIRCRESAHA.117.312058. Epub 2018 Mar 15.

12.

Drug-induced pulmonary arterial hypertension: a primer for clinicians and scientists.

Orcholski ME, Yuan K, Rajasingh C, Tsai H, Shamskhou EA, Dhillon NK, Voelkel NF, Zamanian RT, de Jesus Perez VA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jun 1;314(6):L967-L983. doi: 10.1152/ajplung.00553.2017. Epub 2018 Feb 8.

13.

Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques.

Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC.

Viral Immunol. 2018 Apr;31(3):206-222. doi: 10.1089/vim.2017.0051. Epub 2017 Dec 19.

14.

Cigarette Smoke Is an Endothelial Cell Toxin.

Voelkel NF.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):274. doi: 10.1164/rccm.201706-1123LE. No abstract available.

PMID:
28726501
15.

Sulfated dehydropolymer of caffeic acid: In vitro anti-lung cell death activity and in vivo intervention in emphysema induced by VEGF receptor blockade.

Truong TM, Li H, Dhapare S, Desai UR, Voelkel NF, Sakagami M.

Pulm Pharmacol Ther. 2017 Aug;45:181-190. doi: 10.1016/j.pupt.2017.06.007. Epub 2017 Jun 23.

PMID:
28648907
16.

Leukotriene B4 antagonism ameliorates experimental lymphedema.

Tian W, Rockson SG, Jiang X, Kim J, Begaye A, Shuffle EM, Tu AB, Cribb M, Nepiyushchikh Z, Feroze AH, Zamanian RT, Dhillon GS, Voelkel NF, Peters-Golden M, Kitajewski J, Dixon JB, Nicolls MR.

Sci Transl Med. 2017 May 10;9(389). pii: eaal3920. doi: 10.1126/scitranslmed.aal3920.

PMID:
28490670
17.

p53 Signaling Pathway Polymorphisms Associated With Emphysematous Changes in Patients With COPD.

Mizuno S, Ishizaki T, Kadowaki M, Akai M, Shiozaki K, Iguchi M, Oikawa T, Nakagawa K, Osanai K, Toga H, Gomez-Arroyo J, Kraskauskas D, Cool CD, Bogaard HJ, Voelkel NF.

Chest. 2017 Jul;152(1):58-69. doi: 10.1016/j.chest.2017.03.012. Epub 2017 Mar 15.

PMID:
28315337
18.

Targeting Neurohormonal Activation in Pulmonary Arterial Hypertension: Putting the Puzzle Together.

Gomez-Arroyo J, Voelkel NF, Huizar JF, Abbate A.

JACC Basic Transl Sci. 2017 Feb 27;2(1):36-38. doi: 10.1016/j.jacbts.2016.11.003. eCollection 2017 Feb. No abstract available.

19.

'End-stage' heart failure therapy: potential lessons from congenital heart disease: from pulmonary artery banding and interatrial communication to parallel circulation.

Schranz D, Akintuerk H, Voelkel NF.

Heart. 2017 Feb 15;103(4):262-267. doi: 10.1136/heartjnl-2015-309110. Epub 2016 Dec 23. Review.

20.

Adding complexity to plexogenic arteriopathy.

Voelkel NF, Bogaard HJ.

Eur Respir J. 2016 Dec;48(6):1553-1555. doi: 10.1183/13993003.01867-2016. No abstract available.

21.

The Roles of Immunity in the Prevention and Evolution of Pulmonary Arterial Hypertension.

Nicolls MR, Voelkel NF.

Am J Respir Crit Care Med. 2017 May 15;195(10):1292-1299. doi: 10.1164/rccm.201608-1630PP. No abstract available.

22.

Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease.

Kato R, Mizuno S, Kadowaki M, Shiozaki K, Akai M, Nakagawa K, Oikawa T, Iguchi M, Osanai K, Ishizaki T, Voelkel NF, Toga H.

Respir Res. 2016 Oct 27;17(1):139.

23.

Pulmonary arterial hypertension and the Enigma code of smouldering inflammation.

Gomez-Arroyo J, Abbate A, Voelkel NF.

Eur Respir J. 2016 Aug;48(2):305-7. doi: 10.1183/13993003.00996-2016. No abstract available.

24.

Endothelial hyperpermeability in severe pulmonary arterial hypertension: role of store-operated calcium entry.

Zhou C, Townsley MI, Alexeyev M, Voelkel NF, Stevens T.

Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L560-9. doi: 10.1152/ajplung.00057.2016. Epub 2016 Jul 15.

25.

Right ventricular sugars and fats in chronic thromboembolic pulmonary hypertension.

Sakao S, Daimon M, Voelkel NF, Miyauchi H, Jujo T, Sugiura T, Ishida K, Tanabe N, Kobayashi Y, Tatsumi K.

Int J Cardiol. 2016 Sep 15;219:143-9. doi: 10.1016/j.ijcard.2016.06.010. Epub 2016 Jun 15.

PMID:
27323340
26.

Challenges and opportunities in treating inflammation associated with pulmonary hypertension.

Voelkel NF, Tamosiuniene R, Nicolls MR.

Expert Rev Cardiovasc Ther. 2016 Aug;14(8):939-51. doi: 10.1080/14779072.2016.1180976. Epub 2016 May 4. Review.

27.

Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats.

Happé CM, de Raaf MA, Rol N, Schalij I, Vonk-Noordegraaf A, Westerhof N, Voelkel NF, de Man FS, Bogaard HJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1088-97. doi: 10.1152/ajplung.00023.2016. Epub 2016 Apr 1.

28.

"Nihilism" of chronic heart failure therapy in children and why effective therapy is withheld.

Schranz D, Voelkel NF.

Eur J Pediatr. 2016 Apr;175(4):445-55. doi: 10.1007/s00431-016-2700-3. Epub 2016 Feb 19. Review.

29.

The right ventricle and pulmonary hypertension.

van de Veerdonk MC, Bogaard HJ, Voelkel NF.

Heart Fail Rev. 2016 May;21(3):259-71. doi: 10.1007/s10741-016-9526-y. Review.

PMID:
26833318
30.

Reconciling paradigms of abnormal pulmonary blood flow and quasi-malignant cellular alterations in pulmonary arterial hypertension.

Happé CM, Szulcek R, Voelkel NF, Bogaard HJ.

Vascul Pharmacol. 2016 Aug;83:17-25. doi: 10.1016/j.vph.2016.01.004. Epub 2016 Jan 22. Review.

PMID:
26804008
31.

Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension.

Qian J, Tian W, Jiang X, Tamosiuniene R, Sung YK, Shuffle EM, Tu AB, Valenzuela A, Jiang S, Zamanian RT, Fiorentino DF, Voelkel NF, Peters-Golden M, Stenmark KR, Chung L, Rabinovitch M, Nicolls MR.

Hypertension. 2015 Dec;66(6):1227-1239. doi: 10.1161/HYPERTENSIONAHA.115.06370. Epub 2015 Oct 5.

32.

Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model.

de Raaf MA, Kroeze Y, Middelman A, de Man FS, de Jong H, Vonk-Noordegraaf A, de Korte C, Voelkel NF, Homberg J, Bogaard HJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1164-73. doi: 10.1152/ajplung.00127.2015. Epub 2015 Sep 18.

33.

Increased Right Ventricular Fatty Acid Accumulation in Chronic Thromboembolic Pulmonary Hypertension.

Sakao S, Miyauchi H, Voelkel NF, Sugiura T, Tanabe N, Kobayashi Y, Tatsumi K.

Ann Am Thorac Soc. 2015 Oct;12(10):1465-72. doi: 10.1513/AnnalsATS.201504-236LE.

PMID:
26356218
34.

Determinants of an elevated pulmonary arterial pressure in patients with pulmonary arterial hypertension.

Sakao S, Voelkel NF, Tanabe N, Tatsumi K.

Respir Res. 2015 Jul 8;16:84. doi: 10.1186/s12931-015-0246-y. Review.

35.

Vascular endothelial growth factor receptor 3 signaling contributes to angioobliterative pulmonary hypertension.

Al-Husseini A, Kraskauskas D, Mezzaroma E, Nordio A, Farkas D, Drake JI, Abbate A, Felty Q, Voelkel NF.

Pulm Circ. 2015 Mar;5(1):101-16. doi: 10.1086/679704.

36.
37.

Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.

Al-Husseini A, Wijesinghe DS, Farkas L, Kraskauskas D, Drake JI, Van Tassel B, Abbate A, Chalfant CE, Voelkel NF.

PLoS One. 2015 Mar 18;10(3):e0120157. doi: 10.1371/journal.pone.0120157. eCollection 2015.

38.

Platelet Vascular Endothelial Growth Factor is a Potential Mediator of Transfusion-Related Acute Lung Injury.

Maloney JP, Ambruso DR, Voelkel NF, Silliman CC.

J Pulm Respir Med. 2014;4. pii: 1000212.

39.

[Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology].

Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, Naeije R, Newman J, Oudiz RJ, Provencher S, Torbicki A, Voelkel NF, Hassoun PM.

Turk Kardiyol Dern Ars. 2014 Oct;42 Suppl 1:29-44. Turkish.

40.
41.

Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart.

Toldo S, Mezzaroma E, McGeough MD, Peña CA, Marchetti C, Sonnino C, Van Tassell BW, Salloum FN, Voelkel NF, Hoffman HM, Abbate A.

Cardiovasc Res. 2015 Feb 1;105(2):203-12. doi: 10.1093/cvr/cvu259. Epub 2014 Dec 18.

42.

Heart failure with preserved ejection fraction: refocusing on diastole.

Abbate A, Arena R, Abouzaki N, Van Tassell BW, Canada J, Shah K, Biondi-Zoccai G, Voelkel NF.

Int J Cardiol. 2015 Jan 20;179:430-40. doi: 10.1016/j.ijcard.2014.11.106. Epub 2014 Nov 14. Review.

PMID:
25465302
43.

Iloprost reverses established fibrosis in experimental right ventricular failure.

Gomez-Arroyo J, Sakagami M, Syed AA, Farkas L, Van Tassell B, Kraskauskas D, Mizuno S, Abbate A, Bogaard HJ, Byron PR, Voelkel NF.

Eur Respir J. 2015 Feb;45(2):449-62. doi: 10.1183/09031936.00188013. Epub 2014 Sep 26.

44.

The vascular bed in COPD: pulmonary hypertension and pulmonary vascular alterations.

Sakao S, Voelkel NF, Tatsumi K.

Eur Respir Rev. 2014 Sep;23(133):350-5. doi: 10.1183/09059180.00007913. Review.

45.

Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction.

Gomez-Arroyo J, Sandoval J, Simon MA, Dominguez-Cano E, Voelkel NF, Bogaard HJ.

Ann Am Thorac Soc. 2014 Sep;11(7):1101-15. doi: 10.1513/AnnalsATS.201312-425FR. Review.

PMID:
25079379
46.

Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series).

De Raaf MA, Hussaini AA, Gomez-Arroyo J, Kraskaukas D, Farkas D, Happé C, Voelkel NF, Bogaard HJ.

Pulm Circ. 2014 Jun;4(2):237-43. doi: 10.1086/675986.

47.

Pulmonary vascular diseases: in search of a hub among the spokes-an exercise in hypothesis generation.

Voelkel NF.

Pulm Circ. 2013 Dec;3(4):723-7. doi: 10.1086/674771. No abstract available.

48.

The role of vascular endothelial growth factor in pulmonary arterial hypertension. The angiogenesis paradox.

Voelkel NF, Gomez-Arroyo J.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):474-84. doi: 10.1165/rcmb.2014-0045TR. Review.

PMID:
24932885
49.

Treatment of group I pulmonary arterial hypertension with carvedilol is safe.

Grinnan D, Bogaard HJ, Grizzard J, Van Tassell B, Abbate A, DeWilde C, Priday A, Voelkel NF.

Am J Respir Crit Care Med. 2014 Jun 15;189(12):1562-4. doi: 10.1164/rccm.201311-2025LE. No abstract available.

PMID:
24930531
50.

Sulfated caffeic acid dehydropolymer attenuates elastase and cigarette smoke extract-induced emphysema in rats: sustained activity and a need of pulmonary delivery.

Saluja B, Li H, Desai UR, Voelkel NF, Sakagami M.

Lung. 2014 Aug;192(4):481-92. doi: 10.1007/s00408-014-9597-2. Epub 2014 May 16.

PMID:
24831783

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