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Items: 1 to 50 of 337


Narrowing the gap for bioplastic use in food packaging-an update.

Zhao X, Cornish K, Vodovotz Y.

Environ Sci Technol. 2020 Mar 23. doi: 10.1021/acs.est.9b03755. [Epub ahead of print]


Unsupervised Clustering Analysis Based on MODS Severity Identifies Four Distinct Organ Dysfunction Patterns in Severely Injured Blunt Trauma Patients.

Liu D, Namas RA, Vodovotz Y, Peitzman AB, Simmons RL, Yuan H, Mi Q, Billiar TR.

Front Med (Lausanne). 2020 Feb 25;7:46. doi: 10.3389/fmed.2020.00046. eCollection 2020.


Dose-Dependent Increases in Ellagitannin Metabolites as Biomarkers of Intake in Humans Consuming Standardized Black Raspberry Food Products Designed for Clinical Trials.

Roberts KM, Grainger EM, Thomas-Ahner JM, Hinton A, Gu J, Riedl K, Vodovotz Y, Abaza R, Schwartz SJ, Clinton SK.

Mol Nutr Food Res. 2020 Feb 28:e1900800. doi: 10.1002/mnfr.201900800. [Epub ahead of print]


Diurnal Variation in Systemic Acute Inflammation and Clinical Outcomes Following Severe Blunt Trauma.

Zaaqoq AM, Namas RA, Abdul-Malak O, Almahmoud K, Barclay D, Yin J, Zamora R, Rosengart MR, Billiar TR, Vodovotz Y.

Front Immunol. 2019 Nov 20;10:2699. doi: 10.3389/fimmu.2019.02699. eCollection 2019.


Intestinal-level anti-inflammatory bioactivities of catechin-rich green tea: Rationale, design, and methods of a double-blind, randomized, placebo-controlled crossover trial in metabolic syndrome and healthy adults.

Hodges JK, Zhu J, Yu Z, Vodovotz Y, Brock G, Sasaki GY, Dey P, Bruno RS.

Contemp Clin Trials Commun. 2019 Nov 20;17:100495. doi: 10.1016/j.conctc.2019.100495. eCollection 2020 Mar.


MPPED2 Polymorphism Is Associated With Altered Systemic Inflammation and Adverse Trauma Outcomes.

Schimunek L, Namas RA, Yin J, Barclay D, Liu D, El-Dehaibi F, Abboud A, Cohen M, Zamora R, Billiar TR, Vodovotz Y.

Front Genet. 2019 Nov 8;10:1115. doi: 10.3389/fgene.2019.01115. eCollection 2019.


Decoding the secreted inflammatory response of primary human hepatocytes to hypoxic stress in vitro.

Vodovotz Y, Simmons RL, Barclay D, Yin J, Jefferson BS, Zamora R.

Ann Transl Med. 2019 Aug;7(16):371. doi: 10.21037/atm.2019.07.09.


Quality Control Measures and Validation in Gene Association Studies: Lessons for Acute Illness.

Cohen M, Lamparello AJ, Schimunek L, El-Dehaibi F, Namas RA, Xu Y, Kaynar AM, Billiar TR, Vodovotz Y.

Shock. 2020 Mar;53(3):256-268. doi: 10.1097/SHK.0000000000001409.


An Aging-Related Single-Nucleotide Polymorphism is Associated With Altered Clinical Outcomes and Distinct Inflammatory Profiles in Aged Blunt Trauma Patients.

Lamparello AJ, Namas RA, Schimunek L, Cohen M, El-Dehaibi F, Yin J, Barclay D, Zamora R, Billiar TR, Vodovotz Y.

Shock. 2020 Feb;53(2):146-155. doi: 10.1097/SHK.0000000000001411.


Elevations in Circulating sST2 Levels Are Associated With In-Hospital Mortality and Adverse Clinical Outcomes After Blunt Trauma.

Billiar IM, Guardado J, Abdul-Malak O, Vodovotz Y, Billiar TR, Namas RA.

J Surg Res. 2019 Dec;244:23-33. doi: 10.1016/j.jss.2019.05.057. Epub 2019 Jul 3.


Agent-based models of inflammation in translational systems biology: A decade later.

Vodovotz Y, An G.

Wiley Interdiscip Rev Syst Biol Med. 2019 Nov;11(6):e1460. doi: 10.1002/wsbm.1460. Epub 2019 Jul 1. Review.


Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries.

Almahmoud K, Abboud A, Namas RA, Zamora R, Sperry J, Peitzman AB, Truitt MS, Gaski GE, McKinley TO, Billiar TR, Vodovotz Y.

PLoS One. 2019 Jun 4;14(6):e0217577. doi: 10.1371/journal.pone.0217577. eCollection 2019.


Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.

Seymour CW, Kennedy JN, Wang S, Chang CH, Elliott CF, Xu Z, Berry S, Clermont G, Cooper G, Gomez H, Huang DT, Kellum JA, Mi Q, Opal SM, Talisa V, van der Poll T, Visweswaran S, Vodovotz Y, Weiss JC, Yealy DM, Yende S, Angus DC.

JAMA. 2019 May 28;321(20):2003-2017. doi: 10.1001/jama.2019.5791.


Hepatic Encephalopathy in Children With Acute Liver Failure: Utility of Serum Neuromarkers.

Toney NA, Bell MJ, Belle SH, Hardison RM, Rodriguez-Baez N, Loomes KM, Vodovotz Y, Zamora R, Squires RH; Pediatric Acute Liver Failure Study Group.

J Pediatr Gastroenterol Nutr. 2019 Jul;69(1):108-115. doi: 10.1097/MPG.0000000000002351.


Early Immunologic Response in Multiply Injured Patients With Orthopaedic Injuries Is Associated With Organ Dysfunction.

Gaski GE, Metzger C, McCarroll T, Wessel R, Adler J, Cutshall A, Brown K, Vodovotz Y, Billiar TR, McKinley TO.

J Orthop Trauma. 2019 May;33(5):220-228. doi: 10.1097/BOT.0000000000001437.


HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen.

Zamora R, Barclay D, Yin J, Alonso EM, Leonis MA, Mi Q, Billiar TR, Simmons RL, Squires RH, Vodovotz Y.

Sci Rep. 2019 Apr 12;9(1):5971. doi: 10.1038/s41598-019-42564-5.


Association of a Functional Polymorphism in the CHRFAM7A Gene with Inflammatory Response Mediators and Neuropathic Pain after Spinal Cord Injury.

Huang W, Kabbani N, Brannan TK, Lin MK, Theiss MM, Hamilton JF, Ecklund JM, Conley YP, Vodovotz Y, Brienza D, Wagner AK, Robbins E, Sowa GA, Lipsky RH.

J Neurotrauma. 2019 Nov 1;36(21):3026-3033. doi: 10.1089/neu.2018.6200. Epub 2019 May 23.


Inflammation and Disease: Modelling and Modulation of the Inflammatory Response to Alleviate Critical Illness.

Day JD, Cockrell C, Namas R, Zamora R, An G, Vodovotz Y.

Curr Opin Syst Biol. 2018 Dec;12:22-29. doi: 10.1016/j.coisb.2018.08.008. Epub 2018 Aug 23.


Dietary Black Raspberries Impact the Colonic Microbiome and Phytochemical Metabolites in Mice.

Gu J, Thomas-Ahner JM, Riedl KM, Bailey MT, Vodovotz Y, Schwartz SJ, Clinton SK.

Mol Nutr Food Res. 2019 Apr;63(8):e1800636. doi: 10.1002/mnfr.201800636. Epub 2019 Mar 7.


A conceptual time window-based model for the early stratification of trauma patients.

Lamparello AJ, Namas RA, Constantine G, McKinley TO, Elster E, Vodovotz Y, Billiar TR.

J Intern Med. 2019 Jul;286(1):2-15. doi: 10.1111/joim.12874. Epub 2019 Jan 9. Review.


Computational Analysis Supports IL-17A as a Central Driver of Neutrophil Extracellular Trap-Mediated Injury in Liver Ischemia Reperfusion.

Tohme S, Yazdani HO, Sud V, Loughran P, Huang H, Zamora R, Simmons RL, Vodovotz Y, Tsung A.

J Immunol. 2019 Jan 1;202(1):268-277. doi: 10.4049/jimmunol.1800454. Epub 2018 Nov 30.


Young and Aged Blunt Trauma Patients Display Major Differences in Circulating Inflammatory Mediator Profiles after Severe Injury.

Lamparello AJ, Namas RA, Abdul-Malak O, Vodovotz Y, Billiar TR.

J Am Coll Surg. 2019 Feb;228(2):148-160.e7. doi: 10.1016/j.jamcollsurg.2018.10.019. Epub 2018 Nov 16.


A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice.

Zamora R, Korff S, Mi Q, Barclay D, Schimunek L, Zucca R, Arsiwalla XD, Simmons RL, Verschure P, Billiar TR, Vodovotz Y.

PLoS Comput Biol. 2018 Nov 6;14(11):e1006582. doi: 10.1371/journal.pcbi.1006582. eCollection 2018 Nov.


Rationale and design of technology assisted stepped collaborative care intervention to improve patient-centered outcomes in hemodialysis patients (TÄ€Ccare trial).

Roumelioti ME, Steel JL, Yabes J, Vowles KE, Vodovotz Y, Beach S, Rollman B, Weisbord SD, Unruh ML, Jhamb M.

Contemp Clin Trials. 2018 Oct;73:81-91. doi: 10.1016/j.cct.2018.09.002. Epub 2018 Sep 9.


Effect of galacto-oligosaccharide purity on water sorption and plasticization behavior.

Lans AM, Vodovotz Y.

Food Chem. 2018 Dec 1;268:9-14. doi: 10.1016/j.foodchem.2018.06.008. Epub 2018 Jun 5.


Assessment of chicken breast meat quality after freeze/thaw abuse using magnetic resonance imaging techniques.

Frelka JC, Phinney DM, Yang X, Knopp MV, Heldman DR, Wick MP, Vodovotz Y.

J Sci Food Agric. 2019 Jan 30;99(2):844-853. doi: 10.1002/jsfa.9254. Epub 2018 Aug 29.


IL-17A - A regulator in acute inflammation: Insights from in vitro, in vivo and in silico studies.

Sud V, Abboud A, Tohme S, Vodovotz Y, Simmons RL, Tsung A.

Cytokine. 2018 Jun 25. pii: S1043-4666(18)30116-9. doi: 10.1016/j.cyto.2018.03.030. [Epub ahead of print] Review.


What's New in Shock, June 2018?

Namas R, Vodovotz Y.

Shock. 2018 Jun;49(6):613-615. doi: 10.1097/SHK.0000000000001130. No abstract available.


Prospective Analyses of Cytokine Mediation of Sleep and Survival in the Context of Advanced Cancer.

Steel JL, Terhorst L, Collins KP, Geller DA, Vodovotz Y, Kim J, Krane A, Antoni M, Marsh JW, Burke LE, Butterfield LH, Penedo FJ, Buysse DJ, Tsung A.

Psychosom Med. 2018 Jun;80(5):483-491. doi: 10.1097/PSY.0000000000000579.


Diagnosis and Management of Polytraumatized Patients With Severe Extremity Trauma.

McKinley TO, Gaski GE, Vodovotz Y, Corona BT, Billiar TR.

J Orthop Trauma. 2018 Mar;32 Suppl 1:S1-S6. doi: 10.1097/BOT.0000000000001114. Review.


Suppressed networks of inflammatory mediators characterize chronic venous insufficiency.

Sachdev U, Vodovotz L, Bitner J, Barclay D, Zamora R, Yin J, Simmons RL, Vodovotz Y.

J Vasc Surg Venous Lymphat Disord. 2018 May;6(3):358-366. doi: 10.1016/j.jvsv.2017.11.009. Epub 2018 Feb 10.


"Thinking" vs. "Talking": Differential Autocrine Inflammatory Networks in Isolated Primary Hepatic Stellate Cells and Hepatocytes under Hypoxic Stress.

Vodovotz Y, Simmons RL, Gandhi CR, Barclay D, Jefferson BS, Huang C, Namas R, El-Dehaibi F, Mi Q, Billiar TR, Zamora R.

Front Physiol. 2017 Dec 22;8:1104. doi: 10.3389/fphys.2017.01104. eCollection 2017.


Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice.

Zettel K, Korff S, Zamora R, Morelli AE, Darwiche S, Loughran PA, Elson G, Shang L, Salgado-Pires S, Scott MJ, Vodovotz Y, Billiar TR.

Front Immunol. 2017 Nov 28;8:1672. doi: 10.3389/fimmu.2017.01672. eCollection 2017.


An Enrichment Strategy Yields Seven Novel Single Nucleotide Polymorphisms Associated With Mortality and Altered Th17 Responses Following Blunt Trauma.

Schimunek L, Namas RA, Yin J, Liu D, Barclay D, El-Dehaibi F, Abboud A, Lindberg H, Zamora R, Billiar TR, Vodovotz Y.

Shock. 2018 Mar;49(3):259-268. doi: 10.1097/SHK.0000000000000987.


Modulating conversion of isoflavone glycosides to aglycones using crude beta-glycosidase extracts from almonds and processed soy.

Ahn-Jarvis JH, Teegarden MD, Schwartz SJ, Lee K, Vodovotz Y.

Food Chem. 2017 Dec 15;237:685-692. doi: 10.1016/j.foodchem.2017.05.122. Epub 2017 May 24.


IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.

Xu J, Guardado J, Hoffman R, Xu H, Namas R, Vodovotz Y, Xu L, Ramadan M, Brown J, Turnquist HR, Billiar TR.

PLoS Med. 2017 Jul 25;14(7):e1002365. doi: 10.1371/journal.pmed.1002365. eCollection 2017 Jul.


Time for trauma immunology.

Billiar TR, Vodovotz Y.

PLoS Med. 2017 Jul 11;14(7):e1002342. doi: 10.1371/journal.pmed.1002342. eCollection 2017 Jul.


The role of NIGMS P50 sponsored team science in our understanding of multiple organ failure.

Moore FA, Moore EE, Billiar TR, Vodovotz Y, Banerjee A, Moldawer LL.

J Trauma Acute Care Surg. 2017 Sep;83(3):520-531. doi: 10.1097/TA.0000000000001587.


Differential inflammatory networks distinguish responses to bone marrow-derived versus adipose-derived mesenchymal stem cell therapies in vascularized composite allotransplantation.

Zamora R, Ravuri SK, Plock JA, Vodovotz Y, Gorantla VS.

J Trauma Acute Care Surg. 2017 Jul;83(1 Suppl 1):S50-S58. doi: 10.1097/TA.0000000000001489.


Raspberry ketone fails to reduce adiposity beyond decreasing food intake in C57BL/6 mice fed a high-fat diet.

Cotten BM, Diamond SA, Banh T, Hsiao YH, Cole RM, Li J, Simons CT, Bruno RS, Belury MA, Vodovotz Y.

Food Funct. 2017 Apr 19;8(4):1512-1518. doi: 10.1039/c6fo01831a.


From static to dynamic: a sepsis-specific dynamic model from clinical criteria in polytrauma patients.

Namas RA, Vodovotz Y.

Ann Transl Med. 2016 Dec;4(24):492. doi: 10.21037/atm.2016.11.72. No abstract available.


Inflammatory Mediators Associated With Pressure Ulcer Development in Individuals With Pneumonia After Traumatic Spinal Cord Injury: A Pilot Study.

Krishnan S, Vodovotz Y, Karg PE, Constantine G, Sowa GA, Constantine FJ, Brienza DM.

Arch Phys Med Rehabil. 2017 Sep;98(9):1792-1799. doi: 10.1016/j.apmr.2016.12.018. Epub 2017 Jan 25.


Solving Immunology?

Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC.

Trends Immunol. 2017 Feb;38(2):116-127. doi: 10.1016/ Epub 2016 Dec 13. Review.


Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients.

Abdul-Malak O, Vodovotz Y, Zaaqoq A, Guardado J, Almahmoud K, Yin J, Zuckerbraun B, Peitzman AB, Sperry J, Billiar TR, Namas RA.

Mediators Inflamm. 2016;2016:7950374. Epub 2016 Nov 15.


Data-Driven Modeling for Precision Medicine in Pediatric Acute Liver Failure.

Zamora R, Vodovotz Y, Mi Q, Barclay D, Yin J, Horslen S, Rudnick D, Loomes KM, Squires RH.

Mol Med. 2017 Jan;22:821-829. doi: 10.2119/molmed.2016.00183. Epub 2016 Nov 23.


Machine Perfusion of Porcine Livers with Oxygen-Carrying Solution Results in Reprogramming of Dynamic Inflammation Networks.

Sadowsky D, Zamora R, Barclay D, Yin J, Fontes P, Vodovotz Y.

Front Pharmacol. 2016 Nov 4;7:413. eCollection 2016.


Dynamic Profiling: Modeling the Dynamics of Inflammation and Predicting Outcomes in Traumatic Brain Injury Patients.

Constantine G, Buliga M, Mi Q, Constantine F, Abboud A, Zamora R, Puccio A, Okonkwo D, Vodovotz Y.

Front Pharmacol. 2016 Nov 1;7:383. eCollection 2016.


Application of a low polyphenol or low ellagitannin dietary intervention and its impact on ellagitannin metabolism in men.

Roberts KM, Grainger EM, Thomas-Ahner JM, Hinton A, Gu J, Riedl KM, Vodovotz Y, Abaza R, Schwartz SJ, Clinton SK.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600224. Epub 2017 Jan 17.


Individual-specific principal component analysis of circulating inflammatory mediators predicts early organ dysfunction in trauma patients.

Namas RA, Almahmoud K, Mi Q, Ghuma A, Namas R, Zaaqoq A, Zhu X, Abdul-Malak O, Sperry J, Zamora R, Billiar TR, Vodovotz Y.

J Crit Care. 2016 Dec;36:146-153. doi: 10.1016/j.jcrc.2016.07.002. Epub 2016 Jul 11.

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