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Items: 1 to 50 of 155

1.

A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by ER aminopeptidase 1.

Mavridis G, Arya R, Domnick A, Zoidakis J, Makridakis M, Vlahou A, Mpakali A, Lelis A, Georgiadis D, Tampé R, Papakyriakou A, Stern LJ, Stratikos E.

J Biol Chem. 2020 Mar 17. pii: jbc.RA120.012976. doi: 10.1074/jbc.RA120.012976. [Epub ahead of print]

2.

Multiplexed MRM-based protein quantification of putative prognostic biomarkers for chronic kidney disease progression in plasma.

Makridakis M, Kontostathi G, Petra E, Stroggilos R, Lygirou V, Filip S, Duranton F, Mischak H, Argiles A, Zoidakis J, Vlahou A.

Sci Rep. 2020 Mar 16;10(1):4815. doi: 10.1038/s41598-020-61496-z.

3.

The urinary proteomics classifier chronic kidney disease 273 predicts cardiovascular outcome in patients with chronic kidney disease.

Verbeke F, Siwy J, Van Biesen W, Mischak H, Pletinck A, Schepers E, Neirynck N, Magalhães P, Pejchinovski M, Pontillo C, Lichtinghagen R, Brand K, Vlahou A, De Bacquer D, Glorieux G.

Nephrol Dial Transplant. 2019 Dec 14. pii: gfz242. doi: 10.1093/ndt/gfz242. [Epub ahead of print]

PMID:
31837226
4.

Integrating continuous monitoring and evaluation of risk-adjusted outcomes in a cardiac surgical program.

Ananiadou O, Fazekas L, Vlahou A, Ampatzidou F, Madesis A, Karaiskos T, Drossos G.

J Card Surg. 2020 Jan;35(1):151-157. doi: 10.1111/jocs.14345. Epub 2019 Nov 11.

PMID:
31710753
5.

Proteomics Analysis of Formalin Fixed Paraffin Embedded Tissues in the Investigation of Prostate Cancer.

Mantsiou A, Makridakis M, Fasoulakis K, Katafigiotis I, Constantinides CA, Zoidakis J, Roubelakis MG, Vlahou A, Lygirou V.

J Proteome Res. 2019 Nov 18. doi: 10.1021/acs.jproteome.9b00587. [Epub ahead of print]

PMID:
31682457
6.

Author Correction: Urinary CE-MS peptide marker pattern for detection of solid tumors.

Belczacka I, Latosinska A, Siwy J, Metzger J, Merseburger AS, Mischak H, Vlahou A, Frantzi M, Jankowski V.

Sci Rep. 2019 Sep 3;9(1):12864. doi: 10.1038/s41598-019-49304-9.

7.

Short Term Results of Fibrin Gel Obtained from Cord Blood Units: A Preliminary in Vitro Study.

Mallis P, Gontika I, Dimou Z, Panagouli E, Zoidakis J, Makridakis M, Vlahou A, Georgiou E, Gkioka V, Stavropoulos-Giokas C, Michalopoulos E.

Bioengineering (Basel). 2019 Aug 2;6(3). pii: E66. doi: 10.3390/bioengineering6030066.

8.

Functional secretome analysis reveals Annexin-A1 as important paracrine factor derived from fetal mesenchymal stem cells in hepatic regeneration.

Zagoura D, Trohatou O, Makridakis M, Kollia A, Kokla N, Mokou M, Psaraki A, Eliopoulos AG, Vlahou A, Roubelakis MG.

EBioMedicine. 2019 Jul;45:542-552. doi: 10.1016/j.ebiom.2019.07.009. Epub 2019 Jul 12.

9.

Proteome-based classification of Nonmuscle Invasive Bladder Cancer.

Stroggilos R, Mokou M, Latosinska A, Makridakis M, Lygirou V, Mavrogeorgis E, Drekolias D, Frantzi M, Mullen W, Fragkoulis C, Stasinopoulos K, Papadopoulos G, Stathouros G, Lazaris AC, Makrythanasis P, Ntoumas K, Mischak H, Zoidakis J, Vlahou A.

Int J Cancer. 2020 Jan 1;146(1):281-294. doi: 10.1002/ijc.32556. Epub 2019 Jul 26.

PMID:
31286493
10.

Urinary peptide panel for prognostic assessment of bladder cancer relapse.

Krochmal M, van Kessel KEM, Zwarthoff EC, Belczacka I, Pejchinovski M, Vlahou A, Mischak H, Frantzi M.

Sci Rep. 2019 May 21;9(1):7635. doi: 10.1038/s41598-019-44129-y.

11.

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment.

Schanstra JP, Luong TT, Makridakis M, Van Linthout S, Lygirou V, Latosinska A, Alesutan I, Boehme B, Schelski N, Von Lewinski D, Mullen W, Nicklin S, Delles C, Feuillet G, Denis C, Lang F, Pieske B, Bascands JL, Mischak H, Saulnier-Blache JS, Voelkl J, Vlahou A, Klein J.

JCI Insight. 2019 May 16;4(10). pii: 125638. doi: 10.1172/jci.insight.125638. eCollection 2019 May 16.

12.

Applications of multiple reaction monitoring targeted proteomics assays in human plasma.

Kontostathi G, Makridakis M, Zoidakis J, Vlahou A.

Expert Rev Mol Diagn. 2019 Jun;19(6):499-515. doi: 10.1080/14737159.2019.1615448. Epub 2019 May 17.

PMID:
31057016
13.

Implications of the mitochondrial interactome of mammalian thioredoxin 2 for normal cellular function and disease.

Chasapis CT, Makridakis M, Damdimopoulos AE, Zoidakis J, Lygirou V, Mavroidis M, Vlahou A, Miranda-Vizuete A, Spyrou G, Vlamis-Gardikas A.

Free Radic Biol Med. 2019 Jun;137:59-73. doi: 10.1016/j.freeradbiomed.2019.04.018. Epub 2019 Apr 21.

PMID:
31018154
14.

Protein biomarkers for cardiorenal syndrome.

Petra E, Zoidakis J, Vlahou A.

Expert Rev Proteomics. 2019 Apr;16(4):325-336. doi: 10.1080/14789450.2019.1592682. Epub 2019 Mar 22.

PMID:
30855192
15.

Development and Validation of Multiple Reaction Monitoring (MRM) Assays for Clinical Applications.

Kontostathi G, Makridakis M, Bitsika V, Tsolakos N, Vlahou A, Zoidakis J.

Methods Mol Biol. 2019;1959:205-223. doi: 10.1007/978-1-4939-9164-8_14.

PMID:
30852825
16.

Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease.

Mokou M, Klein J, Makridakis M, Bitsika V, Bascands JL, Saulnier-Blache JS, Mullen W, Sacherer M, Zoidakis J, Pieske B, Mischak H, Roubelakis MG, Schanstra JP, Vlahou A.

EBioMedicine. 2019 Mar;41:91-104. doi: 10.1016/j.ebiom.2019.02.040. Epub 2019 Feb 28.

17.

Diagnostic and Prognostic Performance of Secreted Protein Acidic and Rich in Cysteine (SPARC) Assay for Detecting Primary and Recurrent Urinary Bladder Cancer.

Critselis E, Rava M, Marquez M, Lygirou V, Chatzicharalambous D, Liapi P, Lichtinghagen R, Brand K, Cecchini L, Vlahou A, Malats N, Zoidakis J.

Proteomics Clin Appl. 2019 Mar;13(2):e1800148. doi: 10.1002/prca.201800148. Epub 2019 Jan 30.

PMID:
30632279
18.

Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins.

Brekk OR, Makridakis M, Mavroeidi P, Vlahou A, Xilouri M, Stefanis L.

Mol Cell Neurosci. 2019 Mar;95:1-12. doi: 10.1016/j.mcn.2018.12.006. Epub 2018 Dec 15.

PMID:
30562574
19.

Implementation of Clinical Proteomics: A Step Closer to Personalized Medicine?

Vlahou A.

Proteomics Clin Appl. 2019 Mar;13(2):e1800088. doi: 10.1002/prca.201800088. Epub 2018 Dec 19. Review.

PMID:
30520267
20.

Urinary Glycopeptide Analysis for the Investigation of Novel Biomarkers.

Belczacka I, Pejchinovski M, Krochmal M, Magalhães P, Frantzi M, Mullen W, Vlahou A, Mischak H, Jankowski V.

Proteomics Clin Appl. 2019 May;13(3):e1800111. doi: 10.1002/prca.201800111. Epub 2018 Oct 18.

PMID:
30334612
21.

Proteome of olive non-glandular trichomes reveals protective protein network against (a)biotic challenge.

Roka L, Koudounas K, Daras G, Zoidakis J, Vlahou A, Kalaitzis P, Hatzopoulos P.

J Plant Physiol. 2018 Dec;231:210-218. doi: 10.1016/j.jplph.2018.09.016. Epub 2018 Sep 27.

PMID:
30286324
22.

Role of Cytosolic Serine Hydroxymethyl Transferase 1 (SHMT1) in Phosphate-Induced Vascular Smooth Muscle Cell Calcification.

Boehme B, Schelski N, Makridakis M, Henze L, Vlahou A, Lang F, Pieske B, Alesutan I, Voelkl J.

Kidney Blood Press Res. 2018;43(4):1212-1221. doi: 10.1159/000492248. Epub 2018 Aug 2.

23.

The family of 14-3-3 proteins and specifically 14-3-3σ are up-regulated during the development of renal pathologies.

Rizou M, Frangou EA, Marineli F, Prakoura N, Zoidakis J, Gakiopoulou H, Liapis G, Kavvadas P, Chatziantoniou C, Makridakis M, Vlahou A, Boletis J, Vlahakos D, Goumenos D, Daphnis E, Iatrou C, Charonis AS.

J Cell Mol Med. 2018 Sep;22(9):4139-4149. doi: 10.1111/jcmm.13691. Epub 2018 Jun 28.

24.

Tissue proteomics studies in the investigation of prostate cancer.

Mantsiou A, Vlahou A, Zoidakis J.

Expert Rev Proteomics. 2018 Jul;15(7):593-611. doi: 10.1080/14789450.2018.1491796. Epub 2018 Jul 16. Review.

PMID:
29939814
25.

Proteomics biomarkers for solid tumors: Current status and future prospects.

Belczacka I, Latosinska A, Metzger J, Marx D, Vlahou A, Mischak H, Frantzi M.

Mass Spectrom Rev. 2019 Jan;38(1):49-78. doi: 10.1002/mas.21572. Epub 2018 Jun 11.

PMID:
29889308
26.

Fibulin-3 Attenuates Phosphate-Induced Vascular Smooth Muscle Cell Calcification by Inhibition of Oxidative Stress.

Luong TTD, Schelski N, Boehme B, Makridakis M, Vlahou A, Lang F, Pieske B, Alesutan I, Voelkl J.

Cell Physiol Biochem. 2018;46(4):1305-1316. doi: 10.1159/000489144. Epub 2018 Apr 18.

27.

Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease.

Lygirou V, Latosinska A, Makridakis M, Mullen W, Delles C, Schanstra JP, Zoidakis J, Pieske B, Mischak H, Vlahou A.

J Transl Med. 2018 Apr 17;16(1):104. doi: 10.1186/s12967-018-1476-9.

28.

Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling.

Magalhães P, Pontillo C, Pejchinovski M, Siwy J, Krochmal M, Makridakis M, Carrick E, Klein J, Mullen W, Jankowski J, Vlahou A, Mischak H, Schanstra JP, Zürbig P, Pape L.

Proteomics Clin Appl. 2018 Sep;12(5):e1700163. doi: 10.1002/prca.201700163. Epub 2018 Apr 23.

PMID:
29611317
29.

Urinary CE-MS peptide marker pattern for detection of solid tumors.

Belczacka I, Latosinska A, Siwy J, Metzger J, Merseburger AS, Mischak H, Vlahou A, Frantzi M, Jankowski V.

Sci Rep. 2018 Mar 27;8(1):5227. doi: 10.1038/s41598-018-23585-y. Erratum in: Sci Rep. 2019 Sep 3;9(1):12864.

30.

Evaluation of Peripheral Blood and Cord Blood Platelet Lysates in Isolation and Expansion of Multipotent Mesenchymal Stromal Cells.

Christou I, Mallis P, Michalopoulos E, Chatzistamatiou T, Mermelekas G, Zoidakis J, Vlahou A, Stavropoulos-Giokas C.

Bioengineering (Basel). 2018 Feb 26;5(1). pii: E19. doi: 10.3390/bioengineering5010019.

31.

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

Magalhães P, Pejchinovski M, Markoska K, Banasik M, Klinger M, Švec-Billá D, Rychlík I, Rroji M, Restivo A, Capasso G, Bob F, Schiller A, Ortiz A, Perez-Gomez MV, Cannata P, Sanchez-Niño MD, Naumovic R, Brkovic V, Polenakovic M, Mullen W, Vlahou A, Zürbig P, Pape L, Ferrario F, Denis C, Spasovski G, Mischak H, Schanstra JP.

Sci Rep. 2017 Dec 5;7(1):16915. doi: 10.1038/s41598-017-17083-w.

32.

Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker.

Pontillo C, Zhang ZY, Schanstra JP, Jacobs L, Zürbig P, Thijs L, Ramírez-Torres A, Heerspink HJL, Lindhardt M, Klein R, Orchard T, Porta M, Bilous RW, Charturvedi N, Rossing P, Vlahou A, Schepers E, Glorieux G, Mullen W, Delles C, Verhamme P, Vanholder R, Staessen JA, Mischak H, Jankowski J.

Kidney Int Rep. 2017 Nov;2(6):1066-1075. doi: 10.1016/j.ekir.2017.06.004.

33.

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy.

Krochmal M, Kontostathi G, Magalhães P, Makridakis M, Klein J, Husi H, Leierer J, Mayer G, Bascands JL, Denis C, Zoidakis J, Zürbig P, Delles C, Schanstra JP, Mischak H, Vlahou A.

Sci Rep. 2017 Nov 9;7(1):15160. doi: 10.1038/s41598-017-15359-9.

34.

Cost-effectiveness of screening type 2 diabetes patients for chronic kidney disease progression with the CKD273 urinary peptide classifier as compared to urinary albumin excretion.

Critselis E, Vlahou A, Stel VS, Morton RL.

Nephrol Dial Transplant. 2018 Mar 1;33(3):441-449. doi: 10.1093/ndt/gfx068.

PMID:
29106632
35.

Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention.

Latosinska A, Mokou M, Makridakis M, Mullen W, Zoidakis J, Lygirou V, Frantzi M, Katafigiotis I, Stravodimos K, Hupe MC, Dobrzynski M, Kolch W, Merseburger AS, Mischak H, Roubelakis MG, Vlahou A.

Oncotarget. 2017 Apr 20;8(41):69435-69455. doi: 10.18632/oncotarget.17279. eCollection 2017 Sep 19.

36.

GeLC-MS: A Sample Preparation Method for Proteomics Analysis of Minimal Amount of Tissue.

Makridakis M, Vlahou A.

Methods Mol Biol. 2018;1788:165-175. doi: 10.1007/7651_2017_76.

PMID:
28994030
37.

Clinical Proteomics for Precision Medicine: The Bladder Cancer Case.

Latosinska A, Frantzi M, Vlahou A, Merseburger AS, Mischak H.

Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201700074. Epub 2017 Oct 25. Review.

PMID:
28980455
38.

Urinary Proteomics in Predicting Heart Transplantation Outcomes (uPROPHET)-Rationale and database description.

Huang QF, Trenson S, Zhang ZY, Yang WY, Van Aelst L, Nkuipou-Kenfack E, Wei FF, Mujaj B, Thijs L, Ciarka A, Zoidakis J, Droogné W, Vlahou A, Janssens S, Vanhaecke J, Van Cleemput J, Staessen JA.

PLoS One. 2017 Sep 7;12(9):e0184443. doi: 10.1371/journal.pone.0184443. eCollection 2017.

39.

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis.

Krochmal M, Cisek K, Filip S, Markoska K, Orange C, Zoidakis J, Gakiopoulou C, Spasovski G, Mischak H, Delles C, Vlahou A, Jankowski J.

Sci Rep. 2017 Aug 22;7(1):9091. doi: 10.1038/s41598-017-09393-w.

40.

Voriconazole Antifungal Prophylaxis in Children With Malignancies: A Nationwide Study.

Pana ZD, Kourti M, Vikelouda K, Vlahou A, Katzilakis N, Papageorgiou M, Doganis D, Petrikkos L, Paisiou A, Koliouskas D, Kattamis A, Stiakaki E, Chatzistilianou M, Vasilatou-Kosmidis H, Polychronopoulou S, Grafakos S, Roilides E.

J Pediatr Hematol Oncol. 2018 Jan;40(1):22-26. doi: 10.1097/MPH.0000000000000926.

PMID:
28816795
41.

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

Sorce S, Stocker R, Seredenina T, Holmdahl R, Aguzzi A, Chio A, Depaulis A, Heitz F, Olofsson P, Olsson T, Duveau V, Sanoudou D, Skosgater S, Vlahou A, Wasquel D, Krause KH, Jaquet V.

Free Radic Biol Med. 2017 Nov;112:387-396. doi: 10.1016/j.freeradbiomed.2017.08.006. Epub 2017 Aug 12. Review.

42.

Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis.

Kontostathi G, Zoidakis J, Makridakis M, Lygirou V, Mermelekas G, Papadopoulos T, Vougas K, Vlamis-Gardikas A, Drakakis P, Loutradis D, Vlahou A, Anagnou NP, Pappa KI.

Biomed Res Int. 2017;2017:4180703. doi: 10.1155/2017/4180703. Epub 2017 Feb 2.

43.

The use of urinary proteomics in the assessment of suitability of mouse models for ageing.

Nkuipou-Kenfack E, Schanstra JP, Bajwa S, Pejchinovski M, Vinel C, Dray C, Valet P, Bascands JL, Vlahou A, Koeck T, Borries M, Busch H, Bechtel-Walz W, Huber TB, Rudolph KL, Pich A, Mischak H, Zürbig P.

PLoS One. 2017 Feb 15;12(2):e0166875. doi: 10.1371/journal.pone.0166875. eCollection 2017.

44.

Ten Years of Proteomics in Bladder Cancer: Progress and Future Directions.

Frantzi M, Vlahou A.

Bladder Cancer. 2017 Jan 27;3(1):1-18. doi: 10.3233/BLC-160073. Review.

45.

Proteomics in cardiovascular disease: recent progress and clinical implication and implementation.

Mokou M, Lygirou V, Vlahou A, Mischak H.

Expert Rev Proteomics. 2017 Feb;14(2):117-136. doi: 10.1080/14789450.2017.1274653. Epub 2017 Jan 5. Review.

PMID:
27997814
46.

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis.

Siwy J, Zürbig P, Argiles A, Beige J, Haubitz M, Jankowski J, Julian BA, Linde PG, Marx D, Mischak H, Mullen W, Novak J, Ortiz A, Persson F, Pontillo C, Rossing P, Rupprecht H, Schanstra JP, Vlahou A, Vanholder R.

Nephrol Dial Transplant. 2017 Dec 1;32(12):2079-2089. doi: 10.1093/ndt/gfw337.

47.

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models.

Frantzi M, Klimou Z, Makridakis M, Zoidakis J, Latosinska A, Borràs DM, Janssen B, Giannopoulou I, Lygirou V, Lazaris AC, Anagnou NP, Mischak H, Roubelakis MG, Vlahou A.

Oncotarget. 2016 Oct 25;7(43):70750-70768. doi: 10.18632/oncotarget.12218.

48.

Taking the next step-Advancing bladder cancer management.

Vlahou A, Black PC, Goebell PJ, Kamat AM, Nawroth R, Schmitz-Dräger BJ.

Urol Oncol. 2016 Oct;34(10):435-6. doi: 10.1016/j.urolonc.2016.03.004. No abstract available.

PMID:
27658683
49.

Microhematuria assessment an IBCN consensus-Based upon a critical review of current guidelines.

Schmitz-Dräger BJ, Kuckuck EC, Zuiverloon TC, Zwarthoff EC, Saltzman A, Srivastava A, Hudson MA, Seiler R, Todenhöfer T, Vlahou A, Grossman HB, Schoenberg MP, Sanchez-Carbayo M, Brünn LA, van Rhijn BW, Goebell PJ, Kamat AM, Roupret M, Shariat SF, Kiemeney LA.

Urol Oncol. 2016 Oct;34(10):437-51. doi: 10.1016/j.urolonc.2016.05.030. Epub 2016 Sep 15. Review.

PMID:
27641313
50.

PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease.

Krochmal M, Fernandes M, Filip S, Pontillo C, Husi H, Zoidakis J, Mischak H, Vlahou A, Jankowski J.

Database (Oxford). 2016 Sep 1;2016. pii: baw128. doi: 10.1093/database/baw128. Print 2016.

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