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Items: 24


Plasmodium berghei P47 is essential for ookinete protection from the Anopheles gambiae complement-like response.

Ukegbu CV, Giorgalli M, Yassine H, Ramirez JL, Taxiarchi C, Barillas-Mury C, Christophides GK, Vlachou D.

Sci Rep. 2017 Jul 20;7(1):6026. doi: 10.1038/s41598-017-05917-6.


Plasmodium berghei PIMMS2 Promotes Ookinete Invasion of the Anopheles gambiae Mosquito Midgut.

Ukegbu CV, Akinosoglou KA, Christophides GK, Vlachou D.

Infect Immun. 2017 Jul 19;85(8). pii: e00139-17. doi: 10.1128/IAI.00139-17. Print 2017 Aug.


Glycan heterogeneity on gold nanoparticles increases lectin discrimination capacity in label-free multiplexed bioassays.

Otten L, Vlachou D, Richards SJ, Gibson MI.

Analyst. 2016 Jul 21;141(14):4305-12. doi: 10.1039/c6an00549g. Epub 2016 May 16.


Transcriptional silencing and activation of paternal DNA during Plasmodium berghei zygotic development and transformation to oocyst.

Ukegbu CV, Cho JS, Christophides GK, Vlachou D.

Cell Microbiol. 2015 Aug;17(8):1230-40. doi: 10.1111/cmi.12433. Epub 2015 Mar 30.


Characterization of Plasmodium developmental transcriptomes in Anopheles gambiae midgut reveals novel regulators of malaria transmission.

Akinosoglou KA, Bushell ES, Ukegbu CV, Schlegelmilch T, Cho JS, Redmond S, Sala K, Christophides GK, Vlachou D.

Cell Microbiol. 2015 Feb;17(2):254-68. doi: 10.1111/cmi.12363. Epub 2014 Oct 31.


Cell biological analysis of mosquito midgut invasion: the defensive role of the actin-based ookinete hood.

Schlegelmilch T, Vlachou D.

Pathog Glob Health. 2013 Dec;107(8):480-92. doi: 10.1179/2047772413Z.000000000180.


Infection intensity-dependent responses of Anopheles gambiae to the African malaria parasite Plasmodium falciparum.

Mendes AM, Awono-Ambene PH, Nsango SE, Cohuet A, Fontenille D, Kafatos FC, Christophides GK, Morlais I, Vlachou D.

Infect Immun. 2011 Nov;79(11):4708-15. doi: 10.1128/IAI.05647-11. Epub 2011 Aug 15.


Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.

Bushell ES, Ecker A, Schlegelmilch T, Goulding D, Dougan G, Sinden RE, Christophides GK, Kafatos FC, Vlachou D.

PLoS Pathog. 2009 Aug;5(8):e1000539. doi: 10.1371/journal.ppat.1000539. Epub 2009 Aug 7.


Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites.

Baum J, Papenfuss AT, Mair GR, Janse CJ, Vlachou D, Waters AP, Cowman AF, Crabb BS, de Koning-Ward TF.

Nucleic Acids Res. 2009 Jun;37(11):3788-98. doi: 10.1093/nar/gkp239. Epub 2009 Apr 20.


Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa.

Mendes AM, Schlegelmilch T, Cohuet A, Awono-Ambene P, De Iorio M, Fontenille D, Morlais I, Christophides GK, Kafatos FC, Vlachou D.

PLoS Pathog. 2008 May 16;4(5):e1000069. doi: 10.1371/journal.ppat.1000069.


Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.

Waterhouse RM, Kriventseva EV, Meister S, Xi Z, Alvarez KS, Bartholomay LC, Barillas-Mury C, Bian G, Blandin S, Christensen BM, Dong Y, Jiang H, Kanost MR, Koutsos AC, Levashina EA, Li J, Ligoxygakis P, Maccallum RM, Mayhew GF, Mendes A, Michel K, Osta MA, Paskewitz S, Shin SW, Vlachou D, Wang L, Wei W, Zheng L, Zou Z, Severson DW, Raikhel AS, Kafatos FC, Dimopoulos G, Zdobnov EM, Christophides GK.

Science. 2007 Jun 22;316(5832):1738-43.


The developmental migration of Plasmodium in mosquitoes.

Vlachou D, Schlegelmilch T, Runn E, Mendes A, Kafatos FC.

Curr Opin Genet Dev. 2006 Aug;16(4):384-91. Epub 2006 Jun 21. Review.


Functional genomic analysis of midgut epithelial responses in Anopheles during Plasmodium invasion.

Vlachou D, Schlegelmilch T, Christophides GK, Kafatos FC.

Curr Biol. 2005 Jul 12;15(13):1185-95.


The complex interplay between mosquito positive and negative regulators of Plasmodium development.

Vlachou D, Kafatos FC.

Curr Opin Microbiol. 2005 Aug;8(4):415-21. Review.


Innate immunity in the malaria vector Anopheles gambiae: comparative and functional genomics.

Osta MA, Christophides GK, Vlachou D, Kafatos FC.

J Exp Biol. 2004 Jul;207(Pt 15):2551-63. Review.


Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae.

Christophides GK, Vlachou D, Kafatos FC.

Immunol Rev. 2004 Apr;198:127-48. Review.


Real-time, in vivo analysis of malaria ookinete locomotion and mosquito midgut invasion.

Vlachou D, Zimmermann T, Cantera R, Janse CJ, Waters AP, Kafatos FC.

Cell Microbiol. 2004 Jul;6(7):671-85.


SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development.

Dessens JT, Sidén-Kiamos I, Mendoza J, Mahairaki V, Khater E, Vlachou D, Xu XJ, Kafatos FC, Louis C, Dimopoulos G, Sinden RE.

Mol Microbiol. 2003 Jul;49(2):319-29.


Immunity-related genes and gene families in Anopheles gambiae.

Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT, Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM, Letunic I, Levashina EA, Loukeris TG, Lycett G, Meister S, Michel K, Moita LF, Müller HM, Osta MA, Paskewitz SM, Reichhart JM, Rzhetsky A, Troxler L, Vernick KD, Vlachou D, Volz J, von Mering C, Xu J, Zheng L, Bork P, Kafatos FC.

Science. 2002 Oct 4;298(5591):159-65.


Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes.

Vlachou D, Lycett G, Sidén-Kiamos I, Blass C, Sinden RE, Louis C.

Mol Biochem Parasitol. 2001 Feb;112(2):229-37.


Myosin A expressions in sporogonic stages of Plasmodium.

Margos G, Sidén-Kiamos I, Fowler RE, Gillman TR, Spaccapelo R, Lycett G, Vlachou D, Papagiannakis G, Eling WM, Mitchell GH, Louis C.

Mol Biochem Parasitol. 2000 Dec;111(2):465-9. No abstract available.


Distinct roles for pbs21 and pbs25 in the in vitro ookinete to oocyst transformation of Plasmodium berghei.

Sidén-Kiamos I, Vlachou D, Margos G, Beetsma A, Waters AP, Sinden RE, Louis C.

J Cell Sci. 2000 Oct;113 Pt 19:3419-26.

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