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Items: 1 to 50 of 229

1.

Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum.

Cá B, Fonseca KL, Sousa J, Maceiras AR, Machado D, Sanca L, Rabna P, Rodrigues PNS, Viveiros M, Saraiva M.

Front Microbiol. 2019 Sep 10;10:2102. doi: 10.3389/fmicb.2019.02102. eCollection 2019.

2.

The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin.

Vianna JS, Machado D, Ramis IB, Silva FP, Bierhals DV, Abril MA, von Groll A, Ramos DF, Lourenço MCS, Viveiros M, da Silva PEA.

Antibiotics (Basel). 2019 Sep 18;8(3). pii: E153. doi: 10.3390/antibiotics8030153.

3.

A case report of disseminated Mycobacterium colombiense infection in an HIV patient.

Pena E, Machado D, Viveiros M, Jordão S.

Int J Mycobacteriol. 2019 Jul-Sep;8(3):295-297. doi: 10.4103/ijmy.ijmy_100_19.

4.

In silico and in vitro evaluation of tetrahydropyridine compounds as efflux inhibitors in Mycobacterium abscessus.

Ramis IB, Vianna JS, Silva Junior L, von Groll A, Ramos DF, Lobo MM, Zanatta N, Viveiros M, Silva PEAD.

Tuberculosis (Edinb). 2019 Jul 23;118:101853. doi: 10.1016/j.tube.2019.07.004. [Epub ahead of print]

PMID:
31430699
5.

Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.

Tatara MB, Perdigão J, Viveiros M, Kritski A, Silva KED, Sacchi FPC, de Lima CC, Dos Santos PCP, Diniz JLDCG, Almeida Silva PE, Gomes P, Gomes MMQ, Cunha EAT, Lapa E Silva JR, Portugal I, Croda J, Andrade MKN.

Am J Trop Med Hyg. 2019 Oct;101(4):774-779. doi: 10.4269/ajtmh.19-0324.

PMID:
31392954
6.

Topical cyclosporine A 0.05% before and after surgery to prevent pterygium recurrence.

Meneghim RLFS, Satto LH, Natsuaki KL, Oliveira AC, Padovani CR, Viveiros MMH, Schellini SA.

Arq Bras Oftalmol. 2019 Jun 27;82(5):372-376. doi: 10.5935/0004-2749.20190075.

7.

Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs.

Phelan JE, O'Sullivan DM, Machado D, Ramos J, Oppong YEA, Campino S, O'Grady J, McNerney R, Hibberd ML, Viveiros M, Huggett JF, Clark TG.

Genome Med. 2019 Jun 24;11(1):41. doi: 10.1186/s13073-019-0650-x.

8.

Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections.

Rossi I, Buttini F, Sonvico F, Affaticati F, Martinelli F, Annunziato G, Machado D, Viveiros M, Pieroni M, Bettini R.

Pharmaceutics. 2019 May 1;11(5). pii: E203. doi: 10.3390/pharmaceutics11050203.

9.

Tuberculosis care for migrant patients in Portugal: a mixed methods study with primary healthcare providers.

Tavares AM, Garcia AC, Gama A, Abecasis AB, Viveiros M, Dias S.

BMC Health Serv Res. 2019 Apr 18;19(1):233. doi: 10.1186/s12913-019-4050-0.

10.

Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in Greater Lisbon, Portugal: Implications at the public health level.

Pereira C, Gomes P, Taveira R, Silva C, Maltez F, Macedo R, Costa C, Couvin D, Rastogi N, Viveiros M, Perdigão J, Portugal I.

Infect Genet Evol. 2019 Jul;71:159-165. doi: 10.1016/j.meegid.2019.03.025. Epub 2019 Mar 27.

PMID:
30928606
11.

Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance.

Oppong YEA, Phelan J, Perdigão J, Machado D, Miranda A, Portugal I, Viveiros M, Clark TG, Hibberd ML.

BMC Genomics. 2019 Mar 29;20(1):252. doi: 10.1186/s12864-019-5615-3.

12.

Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants.

Felicetti T, Machado D, Cannalire R, Astolfi A, Massari S, Tabarrini O, Manfroni G, Barreca ML, Cecchetti V, Viveiros M, Sabatini S.

ACS Infect Dis. 2019 Jun 14;5(6):982-1000. doi: 10.1021/acsinfecdis.9b00041. Epub 2019 Apr 4.

PMID:
30907573
13.

Mycobacterium marinum lymphocutaneous infection.

Bouceiro-Mendes R, Ortins-Pina A, Fraga A, Marques T, Viveiros M, Machado D, Soares-de-Almeida L, Freitas JP, Filipe P.

Dermatol Online J. 2019 Feb 15;25(2). pii: 13030/qt5bb78905.

14.

Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus.

Costa SS, Sobkowiak B, Parreira R, Edgeworth JD, Viveiros M, Clark TG, Couto I.

Front Genet. 2019 Jan 9;9:710. doi: 10.3389/fgene.2018.00710. eCollection 2018.

15.

Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus.

Vianna JS, Ramis IB, Bierhals D, von Groll A, Ramos DF, Zanatta N, Lourenço MC, Viveiros M, Almeida da Silva PE.

J Glob Antimicrob Resist. 2019 Jun;17:296-299. doi: 10.1016/j.jgar.2018.12.020. Epub 2019 Jan 7.

PMID:
30630106
16.

Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence.

Machado D, Lecorche E, Mougari F, Cambau E, Viveiros M.

Front Microbiol. 2018 Dec 13;9:3072. doi: 10.3389/fmicb.2018.03072. eCollection 2018.

17.

Advances in the molecular diagnosis of tuberculosis: From probes to genomes.

Machado D, Couto I, Viveiros M.

Infect Genet Evol. 2019 Aug;72:93-112. doi: 10.1016/j.meegid.2018.11.021. Epub 2018 Nov 30.

PMID:
30508687
18.

Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation.

Brynildsrud OB, Pepperell CS, Suffys P, Grandjean L, Monteserin J, Debech N, Bohlin J, Alfsnes K, Pettersson JO, Kirkeleite I, Fandinho F, da Silva MA, Perdigao J, Portugal I, Viveiros M, Clark T, Caws M, Dunstan S, Thai PVK, Lopez B, Ritacco V, Kitchen A, Brown TS, van Soolingen D, O'Neill MB, Holt KE, Feil EJ, Mathema B, Balloux F, Eldholm V.

Sci Adv. 2018 Oct 17;4(10):eaat5869. doi: 10.1126/sciadv.aat5869. eCollection 2018 Oct.

19.

Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics.

Machado D, Azzali E, Couto I, Costantino G, Pieroni M, Viveiros M.

Future Microbiol. 2018 Sep;13:1383-1402. doi: 10.2217/fmb-2018-0110. Epub 2018 Sep 27.

PMID:
30259757
20.

Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data.

Sobkowiak B, Glynn JR, Houben RMGJ, Mallard K, Phelan JE, Guerra-Assunção JA, Banda L, Mzembe T, Viveiros M, McNerney R, Parkhill J, Crampin AC, Clark TG.

BMC Genomics. 2018 Aug 14;19(1):613. doi: 10.1186/s12864-018-4988-z.

21.

Participatory implementation of an antibiotic stewardship programme supported by an innovative surveillance and clinical decision-support system.

Simões AS, Maia MR, Gregório J, Couto I, Asfeldt AM, Simonsen GS, Póvoa P, Viveiros M, Lapão LV.

J Hosp Infect. 2018 Nov;100(3):257-264. doi: 10.1016/j.jhin.2018.07.034. Epub 2018 Jul 30.

PMID:
30071264
22.

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis.

Machado D, Girardini M, Viveiros M, Pieroni M.

Front Microbiol. 2018 Jul 3;9:1367. doi: 10.3389/fmicb.2018.01367. eCollection 2018. Review.

23.

Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus.

Ramis IB, Vianna JS, Reis AJ, von Groll A, Ramos DF, Viveiros M, da Silva PEA.

Planta Med. 2018 Nov;84(17):1265-1270. doi: 10.1055/a-0639-5412. Epub 2018 Jun 18.

PMID:
29913527
24.

Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate.

Machado D, Antunes J, Simões A, Perdigão J, Couto I, McCusker M, Martins M, Portugal I, Pacheco T, Batista J, Toscano C, Viveiros M.

J Med Microbiol. 2018 Jun;67(6):740-749. doi: 10.1099/jmm.0.000741. Epub 2018 May 2.

PMID:
29717972
25.

Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS.

Deveson Lucas D, Crane B, Wright A, Han ML, Moffatt J, Bulach D, Gladman SL, Powell D, Aranda J, Seemann T, Machado D, Pacheco T, Marques T, Viveiros M, Nation R, Li J, Harper M, Boyce JD.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e02442-17. doi: 10.1128/AAC.02442-17. Print 2018 Jul.

26.

Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Ha DM, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Sousa EO, Streicher EM, Van Helden P, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.

Nat Genet. 2018 May;50(5):764. doi: 10.1038/s41588-018-0074-3.

PMID:
29674744
27.

Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.

Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, Silva H, Abilleira F, Brum C, Reis AJ, Macedo M, Scaini JL, Silva AB, Esteves L, Macedo R, Maltez F, Clemente S, Coelho E, Viegas S, Rabna P, Rodrigues A, Taveira N, Jordao L, Kritski A, Lapa E Silva JR, Mokrousov I, Couvin D, Rastogi N, Couto I, Pain A, McNerney R, Clark TG, von Groll A, Dalla-Costa ER, Rossetti ML, Silva PEA, Viveiros M, Portugal I.

Infect Genet Evol. 2019 Aug;72:44-58. doi: 10.1016/j.meegid.2018.03.011. Epub 2018 Mar 17.

28.

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains.

Machado D, Perdigão J, Portugal I, Pieroni M, Silva PA, Couto I, Viveiros M.

Antibiotics (Basel). 2018 Mar 3;7(1). pii: E18. doi: 10.3390/antibiotics7010018.

29.

First report on antimicrobial resistance and molecular characterisation of Salmonella enterica serotype Typhi isolated from human specimens in Luanda, Angola.

Francisco M, Costa SS, Belas A, Ramos J, Couto I, Pomba C, Viveiros M.

J Glob Antimicrob Resist. 2018 Jun;13:246-249. doi: 10.1016/j.jgar.2018.02.001. Epub 2018 Feb 9.

PMID:
29432938
30.

Fighting antibiotic resistance in Portuguese hospitals: Understanding antibiotic prescription behaviours to better design antibiotic stewardship programmes.

Simões AS, Alves DA, Gregório J, Couto I, Dias S, Póvoa P, Viveiros M, Gonçalves L, Lapão LV.

J Glob Antimicrob Resist. 2018 Jun;13:226-230. doi: 10.1016/j.jgar.2018.01.013. Epub 2018 Jan 31.

PMID:
29409949
31.

Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Minh Ha D, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Oliveira Sousa E, Streicher EM, Helden PV, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.

Nat Genet. 2018 Feb;50(2):307-316. doi: 10.1038/s41588-017-0029-0. Epub 2018 Jan 22. Erratum in: Nat Genet. 2018 Apr 19;:.

32.

Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.

Phelan J, de Sessions PF, Tientcheu L, Perdigao J, Machado D, Hasan R, Hasan Z, Bergval IL, Anthony R, McNerney R, Antonio M, Portugal I, Viveiros M, Campino S, Hibberd ML, Clark TG.

Sci Rep. 2018 Jan 9;8(1):160. doi: 10.1038/s41598-017-18188-y.

33.

Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus.

Ramis IB, Figueiredo R, Ramos DF, Halicki PCB, von Groll A, Viveiros M, do Ceu Costa M, da Silva PEA.

Med Chem. 2018;14(4):394-399. doi: 10.2174/1573406414666171204102633.

PMID:
29205119
34.

Eyelid fissure dimensions in Japanese and in Brazilians of European descent over 50 years of age.

Viveiros MMH, Matai O, Takahagi RU, Padovani CR, Schellini SA.

Arq Bras Oftalmol. 2017 Sep-Oct;80(5):304-308. doi: 10.5935/0004-2749.20170074.

35.

Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen.

Costa SS, Viveiros M, Pomba C, Couto I.

J Antimicrob Chemother. 2018 Feb 1;73(2):320-324. doi: 10.1093/jac/dkx400.

PMID:
29126275
36.

Insights on the Mechanism of Action of INH-C10 as an Antitubercular Prodrug.

Vila-Viçosa D, Victor BL, Ramos J, Machado D, Viveiros M, Switala J, Loewen PC, Leitão R, Martins F, Machuqueiro M.

Mol Pharm. 2017 Dec 4;14(12):4597-4605. doi: 10.1021/acs.molpharmaceut.7b00719. Epub 2017 Nov 13.

PMID:
29091448
37.

Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance.

Nakatani Y, Opel-Reading HK, Merker M, Machado D, Andres S, Kumar SS, Moradigaravand D, Coll F, Perdigão J, Portugal I, Schön T, Nair D, Devi KRU, Kohl TA, Beckert P, Clark TG, Maphalala G, Khumalo D, Diel R, Klaos K, Aung HL, Cook GM, Parkhill J, Peacock SJ, Swaminathan S, Viveiros M, Niemann S, Krause KL, Köser CU.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01575-17. doi: 10.1128/AAC.01575-17. Print 2017 Dec.

38.

Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium.

Cannalire R, Machado D, Felicetti T, Santos Costa S, Massari S, Manfroni G, Barreca ML, Tabarrini O, Couto I, Viveiros M, Sabatini S, Cecchetti V.

Eur J Med Chem. 2017 Nov 10;140:321-330. doi: 10.1016/j.ejmech.2017.09.014. Epub 2017 Sep 12.

PMID:
28964936
39.

HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality.

Tavares AM, Fronteira I, Couto I, Machado D, Viveiros M, Abecasis AB, Dias S.

PLoS One. 2017 Sep 28;12(9):e0185526. doi: 10.1371/journal.pone.0185526. eCollection 2017. Review.

40.

Dacryocystectomy as a treatment of chronic dacryocystitis in the elderly.

Meireles MN, Viveiros MM, Meneghin RL, Galindo-Ferreiro A, Marques ME, Schellini SA.

Orbit. 2017 Dec;36(6):419-421. doi: 10.1080/01676830.2017.1353111. Epub 2017 Aug 17.

PMID:
28816565
41.

Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery.

Azzali E, Machado D, Kaushik A, Vacondio F, Flisi S, Cabassi CS, Lamichhane G, Viveiros M, Costantino G, Pieroni M.

J Med Chem. 2017 Aug 24;60(16):7108-7122. doi: 10.1021/acs.jmedchem.7b00793. Epub 2017 Aug 10.

PMID:
28749666
42.

Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.

Santos PFGD, Costa ERD, Ramalho DM, Rossetti ML, Barcellos RB, Nunes LS, Esteves LS, Rodenbusch R, Anthony RM, Bergval I, Sengstake S, Viveiros M, Kritski A, Oliveira MM.

Mem Inst Oswaldo Cruz. 2017 Jun;112(6):396-403. doi: 10.1590/0074-02760160376.

43.

[Scientific Research Policy for Health in Portugal: II - Facts and Suggestions].

Guerreiro CS, Hartz Z, Sambo L, Conceição C, Dussault G, Russo G, Viveiros M, Silveira H, Pita Barros P, Ferrinho P.

Acta Med Port. 2017 Mar 31;30(3):233-242. doi: 10.20344/amp.8012. Epub 2017 Mar 31. Review. Portuguese.

44.

[Scientific Research Policy for Health in Portugal: I - European and National Environment].

Guerreiro CS, Hartz Z, Sambo L, Conceição C, Dussault G, Russo G, Viveiros M, Silveira H, Pita Barros P, Ferrinho P.

Acta Med Port. 2017 Feb 27;30(2):141-147. doi: 10.20344/amp.8011. Epub 2017 Feb 27. Review. Portuguese.

45.

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli.

Machado D, Fernandes L, Costa SS, Cannalire R, Manfroni G, Tabarrini O, Couto I, Sabatini S, Viveiros M.

PeerJ. 2017 Apr 26;5:e3168. doi: 10.7717/peerj.3168. eCollection 2017.

46.

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis.

Machado D, Coelho TS, Perdigão J, Pereira C, Couto I, Portugal I, Maschmann RA, Ramos DF, von Groll A, Rossetti MLR, Silva PA, Viveiros M.

Front Microbiol. 2017 Apr 27;8:711. doi: 10.3389/fmicb.2017.00711. eCollection 2017.

47.

Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola.

Perdigão J, Clemente S, Ramos J, Masakidi P, Machado D, Silva C, Couto I, Viveiros M, Taveira N, Portugal I.

Sci Rep. 2017 Feb 23;7:42814. doi: 10.1038/srep42814.

48.

Error-prone meiotic division and subfertility in mice with oocyte-conditional knockdown of pericentrin.

Baumann C, Wang X, Yang L, Viveiros MM.

J Cell Sci. 2017 Apr 1;130(7):1251-1262. doi: 10.1242/jcs.196188. Epub 2017 Feb 13.

49.

Synthesis and Biological Evaluation of Hybrid 1,5- and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents.

Soares A, Estevao MS, Marques MMB, Kovalishyn V, Latino DARS, Aires-de-Sousa J, Ramos J, Viveiros M, Martins F.

Med Chem. 2017;13(5):439-447. doi: 10.2174/1573406413666170209144003.

PMID:
28185538
50.

In vitro and in silico analysis of the efficiency of tetrahydropyridines as drug efflux inhibitors in Escherichia coli.

Silva L Jr, Carrion LL, von Groll A, Costa SS, Junqueira E, Ramos DF, Cantos J, Seus VR, Couto I, Fernandes LD, Bonacorso HG, Martins MA, Zanatta N, Viveiros M, Machado KS, Almeida da Silva PE.

Int J Antimicrob Agents. 2017 Mar;49(3):308-314. doi: 10.1016/j.ijantimicag.2016.11.024. Epub 2017 Jan 30.

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