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Items: 25

1.

Hemopexin deficiency promotes acute kidney injury in sickle cell disease.

Ofori-Acquah S, Hazra R, Orikogbo OO, Crosby D, Flage B, Ackah EB, Lenhart D, Tan RJ, Vitturi DA, Paintsil V, Owusu-Dabo E, Ghosh S.

Blood. 2020 Feb 10. pii: blood.2019002653. doi: 10.1182/blood.2019002653. [Epub ahead of print]

PMID:
32043112
2.

Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.

Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ.

JCI Insight. 2020 Jan 16;5(1). pii: 128578. doi: 10.1172/jci.insight.128578.

3.

Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice.

Wood KC, Durgin BG, Schmidt HM, Hahn SA, Baust JJ, Bachman T, Vitturi DA, Ghosh S, Ofori-Acquah SF, Mora AL, Gladwin MT, Straub AC.

Blood Adv. 2019 Dec 10;3(23):4104-4116. doi: 10.1182/bloodadvances.2019000621.

4.

Hemoglobin alters vitamin carrier uptake and vitamin D metabolism in proximal tubule cells: implications for sickle cell disease.

Gliozzi ML, Rbaibi Y, Long KR, Vitturi DA, Weisz OA.

Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C993-C1000. doi: 10.1152/ajpcell.00287.2019. Epub 2019 Sep 11.

PMID:
31509446
5.

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis.

Jobbagy S, Vitturi DA, Salvatore SR, Turell L, Pires MF, Kansanen E, Batthyany C, Lancaster JR Jr, Freeman BA, Schopfer FJ.

Redox Biol. 2019 Feb;21:101050. doi: 10.1016/j.redox.2018.11.008. Epub 2018 Nov 22.

6.

Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids.

Fazzari M, Vitturi DA, Woodcock SR, Salvatore SR, Freeman BA, Schopfer FJ.

J Lipid Res. 2019 Feb;60(2):388-399. doi: 10.1194/jlr.M088815. Epub 2018 Dec 13.

7.

Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases.

Schopfer FJ, Vitturi DA, Jorkasky DK, Freeman BA.

Nitric Oxide. 2018 Sep 1;79:31-37. doi: 10.1016/j.niox.2018.06.006. Epub 2018 Jun 23. Review.

8.

In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation.

Villacorta L, Minarrieta L, Salvatore SR, Khoo NK, Rom O, Gao Z, Berman RC, Jobbagy S, Li L, Woodcock SR, Chen YE, Freeman BA, Ferreira AM, Schopfer FJ, Vitturi DA.

Redox Biol. 2018 May;15:522-531. doi: 10.1016/j.redox.2018.01.005. Epub 2018 Jan 12.

9.

Evaluation of 10-Nitro Oleic Acid Bio-Elimination in Rats and Humans.

Salvatore SR, Vitturi DA, Fazzari M, Jorkasky DK, Schopfer FJ.

Sci Rep. 2017 Jan 5;7:39900. doi: 10.1038/srep39900.

10.

The Chemical Basis of Thiol Addition to Nitro-conjugated Linoleic Acid, a Protective Cell-signaling Lipid.

Turell L, Vitturi DA, Coitiño EL, Lebrato L, Möller MN, Sagasti C, Salvatore SR, Woodcock SR, Alvarez B, Schopfer FJ.

J Biol Chem. 2017 Jan 27;292(4):1145-1159. doi: 10.1074/jbc.M116.756288. Epub 2016 Dec 6.

11.

Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling.

Zhou C, Ramaswamy SS, Johnson DE, Vitturi DA, Schopfer FJ, Freeman BA, Hudmon A, Levitan ES.

Sci Rep. 2016 Apr 15;6:23416. doi: 10.1038/srep23416.

12.

Nitrite and nitrate-dependent generation of anti-inflammatory fatty acid nitroalkenes.

Delmastro-Greenwood M, Hughan KS, Vitturi DA, Salvatore SR, Grimes G, Potti G, Shiva S, Schopfer FJ, Gladwin MT, Freeman BA, Gelhaus Wendell S.

Free Radic Biol Med. 2015 Dec;89:333-41. doi: 10.1016/j.freeradbiomed.2015.07.149. Epub 2015 Sep 16.

13.

Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride.

Vitturi DA, Minarrieta L, Salvatore SR, Postlethwait EM, Fazzari M, Ferrer-Sueta G, Lancaster JR Jr, Freeman BA, Schopfer FJ.

Nat Chem Biol. 2015 Jul;11(7):504-10. doi: 10.1038/nchembio.1814. Epub 2015 May 25.

14.

Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase.

Vitturi DA, Chen CS, Woodcock SR, Salvatore SR, Bonacci G, Koenitzer JR, Stewart NA, Wakabayashi N, Kensler TW, Freeman BA, Schopfer FJ.

J Biol Chem. 2013 Aug 30;288(35):25626-37. doi: 10.1074/jbc.M113.486282. Epub 2013 Jul 22.

15.

Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine.

Salvatore SR, Vitturi DA, Baker PR, Bonacci G, Koenitzer JR, Woodcock SR, Freeman BA, Schopfer FJ.

J Lipid Res. 2013 Jul;54(7):1998-2009. doi: 10.1194/jlr.M037804. Epub 2013 Apr 25.

16.

Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo.

Vitturi DA, Sun CW, Harper VM, Thrash-Williams B, Cantu-Medellin N, Chacko BK, Peng N, Dai Y, Wyss JM, Townes T, Patel RP.

Free Radic Biol Med. 2013 Feb;55:119-29. doi: 10.1016/j.freeradbiomed.2012.11.003. Epub 2012 Nov 16.

17.

Conjugated linoleic acid is a preferential substrate for fatty acid nitration.

Bonacci G, Baker PR, Salvatore SR, Shores D, Khoo NK, Koenitzer JR, Vitturi DA, Woodcock SR, Golin-Bisello F, Cole MP, Watkins S, St Croix C, Batthyany CI, Freeman BA, Schopfer FJ.

J Biol Chem. 2012 Dec 28;287(53):44071-82. doi: 10.1074/jbc.M112.401356. Epub 2012 Nov 9.

18.

Current perspectives and challenges in understanding the role of nitrite as an integral player in nitric oxide biology and therapy.

Vitturi DA, Patel RP.

Free Radic Biol Med. 2011 Aug 15;51(4):805-12. doi: 10.1016/j.freeradbiomed.2011.05.037. Epub 2011 Jun 16. Review.

19.

Effects of T- and R-state stabilization on deoxyhemoglobin-nitrite reactions and stimulation of nitric oxide signaling.

Cantu-Medellin N, Vitturi DA, Rodriguez C, Murphy S, Dorman S, Shiva S, Zhou Y, Jia Y, Palmer AF, Patel RP.

Nitric Oxide. 2011 Aug 1;25(2):59-69. doi: 10.1016/j.niox.2011.01.006. Epub 2011 Jan 26.

20.

Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties.

Shoman ME, DuMond JF, Isbell TS, Crawford JH, Brandon A, Honovar J, Vitturi DA, White CR, Patel RP, King SB.

J Med Chem. 2011 Feb 24;54(4):1059-70. doi: 10.1021/jm101432z. Epub 2011 Jan 19.

21.

Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction.

Rodriguez C, Vitturi DA, He J, Vandromme M, Brandon A, Hutchings A, Rue LW 3rd, Kerby JD, Patel RP.

Biochem J. 2009 Aug 27;422(3):423-32. doi: 10.1042/BJ20090735.

22.

A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.

Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RA, Murphy MP.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10764-9. doi: 10.1073/pnas.0903250106. Epub 2009 Jun 15.

23.

Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation.

Vitturi DA, Teng X, Toledo JC, Matalon S, Lancaster JR Jr, Patel RP.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1398-407. doi: 10.1152/ajpheart.01303.2008. Epub 2009 Mar 13.

24.

SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation.

Isbell TS, Sun CW, Wu LC, Teng X, Vitturi DA, Branch BG, Kevil CG, Peng N, Wyss JM, Ambalavanan N, Schwiebert L, Ren J, Pawlik KM, Renfrow MB, Patel RP, Townes TM.

Nat Med. 2008 Jul;14(7):773-7. doi: 10.1038/nm1771. Epub 2008 May 30.

25.

Membrane "lens" effect: focusing the formation of reactive nitrogen oxides from the *NO/O2 reaction.

Möller MN, Li Q, Vitturi DA, Robinson JM, Lancaster JR Jr, Denicola A.

Chem Res Toxicol. 2007 Apr;20(4):709-14. Epub 2007 Mar 28.

PMID:
17388608

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