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Items: 49

1.

Interleukin-37 Protects Stem Cell-Based Cartilage Formation in an Inflammatory Osteoarthritis-Like Microenvironment.

van Geffen EW, van Caam APM, Vitters EL, van Beuningen HM, van de Loo FA, van Lent PLEM, Koenders MI, van der Kraan PM.

Tissue Eng Part A. 2019 Aug;25(15-16):1155-1166. doi: 10.1089/ten.TEA.2018.0267. Epub 2019 Mar 28.

PMID:
30526407
2.

Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells.

van den Akker GG, van Beuningen HM, Vitters EL, Koenders MI, van de Loo FA, van Lent PL, Blaney Davidson EN, van der Kraan PM.

Cell Signal. 2017 Dec;40:190-199. doi: 10.1016/j.cellsig.2017.09.010. Epub 2017 Sep 21.

PMID:
28943409
3.

SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells.

de Kroon LM, Narcisi R, van den Akker GG, Vitters EL, Blaney Davidson EN, van Osch GJ, van der Kraan PM.

Sci Rep. 2017 Feb 27;7:43164. doi: 10.1038/srep43164.

4.

IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes.

van Geffen EW, van Caam AP, van Beuningen HM, Vitters EL, Schreurs W, van de Loo FA, van Lent PL, Koenders MI, Blaney Davidson EN, van der Kraan PM.

Rheumatology (Oxford). 2017 Mar 1;56(3):351-361. doi: 10.1093/rheumatology/kew411.

PMID:
27940589
5.

Expression of TGF-β Signaling Regulator RBPMS (RNA-Binding Protein With Multiple Splicing) Is Regulated by IL-1β and TGF-β Superfamily Members, and Decreased in Aged and Osteoarthritic Cartilage.

Shanmugaapriya S, van Caam A, de Kroon L, Vitters EL, Walgreen B, van Beuningen H, Davidson EB, van der Kraan PM.

Cartilage. 2016 Oct;7(4):333-45. doi: 10.1177/1947603515623991. Epub 2016 Feb 24.

6.

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

Blaney Davidson EN, van Caam AP, Vitters EL, Bennink MB, Thijssen E, van den Berg WB, Koenders MI, van Lent PL, van de Loo FA, van der Kraan PM.

Osteoarthritis Cartilage. 2015 Mar;23(3):478-86. doi: 10.1016/j.joca.2014.12.005. Epub 2014 Dec 18.

7.

Gene expression analysis of murine and human osteoarthritis synovium reveals elevation of transforming growth factor β-responsive genes in osteoarthritis-related fibrosis.

Remst DF, Blom AB, Vitters EL, Bank RA, van den Berg WB, Blaney Davidson EN, van der Kraan PM.

Arthritis Rheumatol. 2014 Mar;66(3):647-56. doi: 10.1002/art.38266.

8.

Inhibition of TAK1 and/or JAK can rescue impaired chondrogenic differentiation of human mesenchymal stem cells in osteoarthritis-like conditions.

van Beuningen HM, de Vries-van Melle ML, Vitters EL, Schreurs W, van den Berg WB, van Osch GJ, van der Kraan PM.

Tissue Eng Part A. 2014 Aug;20(15-16):2243-52. doi: 10.1089/ten.TEA.2013.0553. Epub 2014 Mar 25.

9.

Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage.

Blaney Davidson EN, Vitters EL, Bennink MB, van Lent PL, van Caam AP, Blom AB, van den Berg WB, van de Loo FA, van der Kraan PM.

Ann Rheum Dis. 2015 Jun;74(6):1257-64. doi: 10.1136/annrheumdis-2013-204528. Epub 2014 Jan 21.

PMID:
24448347
10.

Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice.

Balemans MC, Ansar M, Oudakker AR, van Caam AP, Bakker B, Vitters EL, van der Kraan PM, de Bruijn DR, Janssen SM, Kuipers AJ, Huibers MM, Maliepaard EM, Walboomers XF, Benevento M, Nadif Kasri N, Kleefstra T, Zhou H, Van der Zee CE, van Bokhoven H.

Dev Biol. 2014 Feb 15;386(2):395-407. doi: 10.1016/j.ydbio.2013.12.016. Epub 2013 Dec 19.

11.

TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling.

Remst DF, Blaney Davidson EN, Vitters EL, Bank RA, van den Berg WB, van der Kraan PM.

Cell Tissue Res. 2014 Jan;355(1):163-71. doi: 10.1007/s00441-013-1740-5. Epub 2013 Nov 6.

PMID:
24192939
12.

Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression.

Remst DF, Blaney Davidson EN, Vitters EL, Blom AB, Stoop R, Snabel JM, Bank RA, van den Berg WB, van der Kraan PM.

Osteoarthritis Cartilage. 2013 Jan;21(1):157-64. doi: 10.1016/j.joca.2012.10.002. Epub 2012 Oct 13.

13.

Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells.

Heldens GT, Blaney Davidson EN, Vitters EL, Schreurs BW, Piek E, van den Berg WB, van der Kraan PM.

Tissue Eng Part A. 2012 Jan;18(1-2):45-54. doi: 10.1089/ten.TEA.2011.0083. Epub 2011 Oct 17.

PMID:
21770865
14.

Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification.

Hellingman CA, Davidson EN, Koevoet W, Vitters EL, van den Berg WB, van Osch GJ, van der Kraan PM.

Tissue Eng Part A. 2011 Apr;17(7-8):1157-67. doi: 10.1089/ten.TEA.2010.0043. Epub 2011 Jan 17.

PMID:
21142619
15.

Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.

Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, van der Kraan PM.

J Immunol. 2009 Jun 15;182(12):7937-45. doi: 10.4049/jimmunol.0803991. Erratum in: J Immunol. 2010 Aug 15;185(4):2629.

16.

Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation.

Blaney Davidson EN, Vitters EL, van Beuningen HM, van de Loo FA, van den Berg WB, van der Kraan PM.

Arthritis Rheum. 2007 Dec;56(12):4065-73.

17.

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.

Blaney Davidson EN, Vitters EL, van Lent PL, van de Loo FA, van den Berg WB, van der Kraan PM.

Arthritis Res Ther. 2007;9(5):R102.

18.

Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage.

Blaney Davidson EN, Vitters EL, Mooren FM, Oliver N, Berg WB, van der Kraan PM.

Arthritis Rheum. 2006 May;54(5):1653-61.

19.

TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7.

Blaney Davidson EN, Vitters EL, van den Berg WB, van der Kraan PM.

Arthritis Res Ther. 2006;8(3):R65. Epub 2006 Mar 29.

21.

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity.

Blaney Davidson EN, Scharstuhl A, Vitters EL, van der Kraan PM, van den Berg WB.

Arthritis Res Ther. 2005;7(6):R1338-47. Epub 2005 Sep 30.

22.

Elucidation of IL-1/TGF-beta interactions in mouse chondrocyte cell line by genome-wide gene expression.

Takahashi N, Rieneck K, van der Kraan PM, van Beuningen HM, Vitters EL, Bendtzen K, van den Berg WB.

Osteoarthritis Cartilage. 2005 May;13(5):426-38.

24.

Large scale protein production of the extracellular domain of the transforming growth factor-beta type II receptor using the Pichia pastoris expression system.

Scharstuhl A, Glansbeek H, Vitters EL, van der Kraan PM, van den Berg WB.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Mar 25;786(1-2):271-7.

PMID:
12651023
25.

Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice.

Scharstuhl A, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB.

Ann Rheum Dis. 2002 Dec;61(12):1095-8.

26.

Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair.

Scharstuhl A, Glansbeek HL, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB.

J Immunol. 2002 Jul 1;169(1):507-14.

27.

Role of nitric oxide in the inhibition of BMP-2-mediated stimulation of proteoglycan synthesis in articular cartilage.

van der Kraan PM, Vitters EL, van Beuningen HM, van de Loo FA, van den Berg WB.

Osteoarthritis Cartilage. 2000 Mar;8(2):82-6.

28.

Collagen type I antisense and collagen type IIA messenger RNA is expressed in adult murine articular cartilage.

van der Kraan PM, Vitters EL, Meijers TH, Poole AR, van den Berg WB.

Osteoarthritis Cartilage. 1998 Nov;6(6):417-26.

29.
30.

Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-beta into murine knee joints.

Glansbeek HL, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB.

Lab Invest. 1998 Feb;78(2):133-42.

PMID:
9484711
31.

Bone morphogenetic protein 2 stimulates articular cartilage proteoglycan synthesis in vivo but does not counteract interleukin-1alpha effects on proteoglycan synthesis and content.

Glansbeek HL, van Beuningen HM, Vitters EL, Morris EA, van der Kraan PM, van den Berg WB.

Arthritis Rheum. 1997 Jun;40(6):1020-8.

PMID:
9182911
32.

Species-specific expression of type II TGF-beta receptor isoforms by articular chondrocytes: effect of proteoglycan depletion and aging.

Glansbeek HL, van der Kraan PM, Lafeber FP, Vitters EL, van den Berg WB.

Cytokine. 1997 May;9(5):347-51.

PMID:
9195134
33.
34.

Analysis of changes in proteoglycan content in murine articular cartilage using image analysis.

van der Kraan PM, de Lange J, Vitters EL, van Beuningen HM, van Osch GJ, van Lent PL, van den Berg WB.

Osteoarthritis Cartilage. 1994 Sep;2(3):207-14.

PMID:
11550680
35.
36.
37.

Maintenance of the synthesis of large proteoglycans in anatomically intact murine articular cartilage by steroids and insulin-like growth factor I.

van der Kraan PM, Vitters EL, Postma NS, Verbunt J, van den Berg WB.

Ann Rheum Dis. 1993 Oct;52(10):734-41.

38.

Induction of osteoarthritis by intra-articular injection of collagenase in mice. Strain and sex related differences.

van Osch GJ, van der Kraan PM, Vitters EL, Blankevoort L, van den Berg WB.

Osteoarthritis Cartilage. 1993 Jul;1(3):171-7.

PMID:
15449423
39.

Variable TGF-beta receptor expression regulates TGF-beta responses of articular chondrocytes.

Glansbeek HL, van der Kraan PM, Vitters EL, van den Berg WB.

Agents Actions Suppl. 1993;39:139-45.

PMID:
8384401
40.

Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.

Lafeber FP, van der Kraan PM, van Roy HL, Vitters EL, Huber-Bruning O, van den Berg WB, Bijlsma JW.

Am J Pathol. 1992 Jun;140(6):1421-9.

41.
42.
43.

High susceptibility of human articular cartilage glycosaminoglycan synthesis to changes in inorganic sulfate availability.

van der Kraan PM, Vitters EL, de Vries BJ, van den Berg WB.

J Orthop Res. 1990 Jul;8(4):565-71.

PMID:
2355296
44.

The effect of chronic paracetamol administration to rats on the glycosaminoglycan content of patellar cartilage.

van der Kraan PM, Vitters EL, de Vries BJ, van den Berg WB, van de Putte LB.

Agents Actions. 1990 Mar;29(3-4):218-23.

PMID:
2339668
45.

Degenerative knee joint lesions in mice after a single intra-articular collagenase injection. A new model of osteoarthritis.

van der Kraan PM, Vitters EL, van Beuningen HM, van de Putte LB, van den Berg WB.

J Exp Pathol (Oxford). 1990 Feb;71(1):19-31.

46.

Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints.

van der Kraan PM, Vitters EL, van de Putte LB, van den Berg WB.

Am J Pathol. 1989 Dec;135(6):1001-14.

47.

The effect of low sulfate concentrations on the glycosaminoglycan synthesis in anatomically intact articular cartilage of the mouse.

van der Kraan PM, de Vries BJ, Vitters EL, van den Berg WB, van de Putte LB.

J Orthop Res. 1989;7(5):645-53.

PMID:
2503596
48.

Inhibition of glycosaminoglycan synthesis in anatomically intact rat patellar cartilage by paracetamol-induced serum sulfate depletion.

van der Kraan PM, de Vries BJ, Vitters EL, van den Berg WB, van de Putte LB.

Biochem Pharmacol. 1988 Oct 1;37(19):3683-90.

PMID:
3178880
49.

Synthesis of aberrant glycosaminoglycans during cartilage culture in 'sulfate free' medium.

van der Kraan PM, Vitters EL, de Vries BJ, van den Berg WB, van de Putte LB.

J Biochem Biophys Methods. 1988 Mar;15(5):273-7.

PMID:
3379241

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