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Items: 1 to 50 of 198

1.

Fish oil supplementation with various lipid emulsions suppresses in vitro cytokine release in home parenteral nutrition patients: a crossover study.

Novak F, Vecka M, Meisnerova E, Sevela S, Vavrova L, Rychlikova J, Dolezalova L, Myslivcova D, Zak A, Vitek L, Novakova O.

Nutr Res. 2019 Oct 23. pii: S0271-5317(19)30600-1. doi: 10.1016/j.nutres.2019.10.004. [Epub ahead of print]

PMID:
31759770
2.

Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements.

Viktorova J, Stranska-Zachariasova M, Fenclova M, Vitek L, Hajslova J, Kren V, Ruml T.

Antioxidants (Basel). 2019 Aug 18;8(8). pii: E317. doi: 10.3390/antiox8080317.

3.

Bilirubin as a predictor of diseases of civilization. Is it time to establish decision limits for serum bilirubin concentrations?

Vítek L.

Arch Biochem Biophys. 2019 Sep 15;672:108062. doi: 10.1016/j.abb.2019.108062. Epub 2019 Jul 31. Review.

PMID:
31376369
4.

Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes.

Fenclova M, Novakova A, Viktorova J, Jonatova P, Dzuman Z, Ruml T, Kren V, Hajslova J, Vitek L, Stranska-Zachariasova M.

Sci Rep. 2019 Jul 31;9(1):11118. doi: 10.1038/s41598-019-47250-0.

5.

Evaluating an Outpatient With an Elevated Bilirubin.

Méndez-Sánchez N, Qi X, Vitek L, Arrese M.

Am J Gastroenterol. 2019 Aug;114(8):1185-1188. doi: 10.14309/ajg.0000000000000336. No abstract available.

PMID:
31318706
6.

Iron overload reduces synthesis and elimination of bile acids in rat liver.

Prasnicka A, Lastuvkova H, Alaei Faradonbeh F, Cermanova J, Hroch M, Mokry J, Dolezelova E, Pavek P, Zizalova K, Vitek L, Nachtigal P, Micuda S.

Sci Rep. 2019 Jul 5;9(1):9780. doi: 10.1038/s41598-019-46150-7.

7.

Hyperbilirubinemia in Gunn Rats is Associated with Decreased Inflammatory Response in LPS-Mediated Systemic Inflammation.

Valaskova P, Dvorak A, Lenicek M, Zizalova K, Kutinova-Canova N, Zelenka J, Cahova M, Vitek L, Muchova L.

Int J Mol Sci. 2019 May 9;20(9). pii: E2306. doi: 10.3390/ijms20092306.

8.

Association between plasma bilirubin and mortality.

Vitek L, Hubacek JA, Pajak A, Doryńska A, Kozela M, Eremiasova L, Danzig V, Stefler D, Bobak M.

Ann Hepatol. 2019 Mar - Apr;18(2):379-385. doi: 10.1016/j.aohep.2019.02.001. Epub 2019 Apr 18.

9.

Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice.

Šuk J, Jašprová J, Biedermann D, Petrásková L, Valentová K, Křen V, Muchová L, Vítek L.

Oxid Med Cell Longev. 2019 Feb 12;2019:6026902. doi: 10.1155/2019/6026902. eCollection 2019.

10.

Correction: The effect of light wavelength on in vitro bilirubin photodegradation and photoisomer production.

Vreman HJ, Kourula S, Jašprová J, Ludvíková L, Klán P, Muchová L, Vítek L, Cline BK, Wong RJ, Stevenson DK.

Pediatr Res. 2019 May;85(6):905. doi: 10.1038/s41390-019-0356-1.

PMID:
30814644
11.

The effect of light wavelength on in vitro bilirubin photodegradation and photoisomer production.

Vreman HJ, Kourula S, Jašprová J, Ludvíková L, Klán P, Muchová L, Vítek L, Cline BK, Wong RJ, Stevenson DK.

Pediatr Res. 2019 May;85(6):865-873. doi: 10.1038/s41390-019-0310-2. Epub 2019 Jan 26. Erratum in: Pediatr Res. 2019 Feb 27;:.

PMID:
30710116
12.

Bilirubin: from an unimportant waste product to important myocardial infarction predictor.

Hubáček JA, Vítek L.

Vnitr Lek. Winter 2019;64(12):1148-1152.

PMID:
30704249
13.

Induction of Mild Hyperbilirubinemia: Hype or Real Therapeutic Opportunity?

Vitek L, Bellarosa C, Tiribelli C.

Clin Pharmacol Ther. 2019 Sep;106(3):568-575. doi: 10.1002/cpt.1341. Epub 2019 Mar 1. Review.

PMID:
30588615
14.

May circulating steroids reveal a predisposition to intrahepatic cholestasis of pregnancy in non-pregnant women?

Šimják P, Hill M, Pařízek A, Vítek L, Velíková M, Dušková M, Kancheva R, Bulant J, Koucký M, Kokrdová Z, Adamcová K, Černý A, Hájek Z, Stárka L.

Physiol Res. 2018 Nov 28;67(Suppl 3):S499-S510.

15.

Heme Oxygenase-1 May Affect Cell Signalling via Modulation of Ganglioside Composition.

Šmíd V, Šuk J, Kachamakova-Trojanowska N, Jašprová J, Valášková P, Józkowicz A, Dulak J, Šmíd F, Vítek L, Muchová L.

Oxid Med Cell Longev. 2018 Sep 19;2018:3845027. doi: 10.1155/2018/3845027. eCollection 2018.

16.

Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting.

Štacko P, Muchová L, Vítek L, Klán P.

Org Lett. 2018 Aug 17;20(16):4907-4911. doi: 10.1021/acs.orglett.8b02043. Epub 2018 Jul 31.

PMID:
30062897
17.

Chlorophyll-Mediated Changes in the Redox Status of Pancreatic Cancer Cells Are Associated with Its Anticancer Effects.

Vaňková K, Marková I, Jašprová J, Dvořák A, Subhanová I, Zelenka J, Novosádová I, Rasl J, Vomastek T, Sobotka R, Muchová L, Vítek L.

Oxid Med Cell Longev. 2018 Jul 2;2018:4069167. doi: 10.1155/2018/4069167. eCollection 2018.

18.

Metabolomic-based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts.

Mayo R, Crespo J, Martínez-Arranz I, Banales JM, Arias M, Mincholé I, Aller de la Fuente R, Jimenez-Agüero R, Alonso C, de Luis DA, Vitek L, Stritesky J, Caballería J, Romero-Gómez M, Martín-Duce A, Mugüerza Huguet JM, Busteros-Moraza JI, Idowu MO, Castro A, Martínez-Chantar ML, Ortiz P, Bruha R, Lu SC, Bedossa P, Noureddin M, Sanyal AJ, Mato JM.

Hepatol Commun. 2018 May 4;2(7):807-820. doi: 10.1002/hep4.1188. eCollection 2018 Jul.

19.

Neuro-inflammatory effects of photodegradative products of bilirubin.

Jašprová J, Dal Ben M, Hurný D, Hwang S, Žížalová K, Kotek J, Wong RJ, Stevenson DK, Gazzin S, Tiribelli C, Vítek L.

Sci Rep. 2018 May 10;8(1):7444. doi: 10.1038/s41598-018-25684-2.

20.

Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.

Gbelcová H, Rimpelová S, Knejzlík Z, Šáchová J, Kolář M, Strnad H, Repiská V, D'Acunto WC, Ruml T, Vítek L.

Lipids Health Dis. 2017 Dec 20;16(1):250. doi: 10.1186/s12944-017-0641-0.

21.

Bile Acids in the Treatment of Cardiometabolic Diseases.

Vítek L.

Ann Hepatol. 2017 Nov;16 Suppl 1:S43-S52. doi: 10.5604/01.3001.0010.5496.

22.

Bile Acids in the Treatment of Cardiometabolic Diseases.

Vítek L.

Ann Hepatol. 2017 Nov;16(Suppl. 1: s3-105.):s43-s52. doi: 10.5604/01.3001.0010.5496. Review.

23.

Serum Bilirubin Levels and Promoter Variations in HMOX1 and UGT1A1 Genes in Patients with Fabry Disease.

Jirásková A, Bortolussi G, Dostálová G, Eremiášová L, Golaň L, Danzig V, Linhart A, Vítek L.

Oxid Med Cell Longev. 2017;2017:9478946. doi: 10.1155/2017/9478946. Epub 2017 Aug 16.

24.

Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats.

Prasnicka A, Cermanova J, Hroch M, Dolezelova E, Rozkydalova L, Smutny T, Carazo A, Chladek J, Lenicek M, Nachtigal P, Vitek L, Pavek P, Micuda S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec;1862(12):1469-1480. doi: 10.1016/j.bbalip.2017.09.003. Epub 2017 Sep 6.

PMID:
28888833
25.

Bilirubin and atherosclerotic diseases.

Vítek L.

Physiol Res. 2017 Apr 5;66(Supplementum 1):S11-S20. Review.

26.

Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model.

Vodret S, Bortolussi G, Jašprová J, Vitek L, Muro AF.

J Neuroinflammation. 2017 Mar 24;14(1):64. doi: 10.1186/s12974-017-0838-1.

27.

Variability in statin-induced changes in gene expression profiles of pancreatic cancer.

Gbelcová H, Rimpelová S, Ruml T, Fenclová M, Kosek V, Hajšlová J, Strnad H, Kolář M, Vítek L.

Sci Rep. 2017 Mar 9;7:44219. doi: 10.1038/srep44219.

28.

High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway.

Kosek V, Stránská M, Fenclová M, Ruml T, Vítek L, Hajšlová J.

J Chromatogr A. 2017 Mar 17;1489:86-94. doi: 10.1016/j.chroma.2017.01.084. Epub 2017 Jan 31.

PMID:
28209347
29.

Valproic acid downregulates heme oxygenase-1 independently of Nrf2 by increasing ubiquitination and proteasomal degradation.

Jez M, Ciesla M, Stepniewski J, Langrzyk A, Muchova L, Vitek L, Jozkowicz A, Dulak J.

Biochem Biophys Res Commun. 2017 Mar 25;485(1):160-166. doi: 10.1016/j.bbrc.2017.02.041. Epub 2017 Feb 8.

PMID:
28189672
30.

Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.

Bockor L, Bortolussi G, Vodret S, Iaconcig A, Jašprová J, Zelenka J, Vitek L, Tiribelli C, Muro AF.

Hum Mol Genet. 2017 Jan 1;26(1):145-157. doi: 10.1093/hmg/ddw375.

PMID:
28025333
31.

The molecular basis of jaundice: An old symptom revisited.

Gazzin S, Masutti F, Vitek L, Tiribelli C.

Liver Int. 2017 Aug;37(8):1094-1102. doi: 10.1111/liv.13351. Epub 2017 Jan 11. Review.

PMID:
28004508
32.

Background levels of neomorphic 2-hydroxyglutarate facilitate proliferation of primary fibroblasts.

Dvořák A, Zelenka J, Smolková K, Vítek L, JeŽek P.

Physiol Res. 2017 May 4;66(2):293-304. Epub 2016 Dec 16.

33.

Predictive role BLVRA mRNA expression in hepatocellular cancer.

Kubícková KN, Subhanová I, Konícková R, Matousová L, Urbánek P, Parobková H, Kupec M, Pudil J, Vítek L.

Ann Hepatol. 2016 Nov-Dec 2016;15(6):881-887.

34.

Changes in Liver Ganglioside Metabolism in Obstructive Cholestasis - the Role of Oxidative Stress.

Šmíd V, Petr T, Váňová K, Jašprová J, Šuk J, Vítek L, Šmíd F, Muchová L.

Folia Biol (Praha). 2016;62(4):148-59.

35.

Comparison of simple extraction procedures in liquid chromatography-mass spectrometry based determination of serum 7α-hydroxy-4-cholesten-3-one, a surrogate marker of bile acid synthesis.

LeníĿek M, Vecka M, Žížalová K, Vítek L.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:317-320. doi: 10.1016/j.jchromb.2016.08.046. Epub 2016 Aug 31.

PMID:
27598558
36.

Bilirubin-induced ER stress contributes to the inflammatory response and apoptosis in neuronal cells.

Qaisiya M, Brischetto C, Jašprová J, Vitek L, Tiribelli C, Bellarosa C.

Arch Toxicol. 2017 Apr;91(4):1847-1858. doi: 10.1007/s00204-016-1835-3. Epub 2016 Aug 30.

PMID:
27578021
37.

Hyperbilirubinemia Protects against Aging-Associated Inflammation and Metabolic Deterioration.

Zelenka J, Dvořák A, Alán L, Zadinová M, Haluzík M, Vítek L.

Oxid Med Cell Longev. 2016;2016:6190609. doi: 10.1155/2016/6190609. Epub 2016 Jul 31.

38.

The effect of colesevelam treatment on bile acid and lipid metabolism and glycemic control in healthy men.

Blahová T, Peterková L, Leníček M, Vlachová M, Zemánková K, Adámková V, Vítek L, Kovář J.

Physiol Res. 2016 Dec 13;65(6):995-1003. Epub 2016 Aug 19.

39.

A Novel Perspective on the Biology of Bilirubin in Health and Disease.

Gazzin S, Vitek L, Watchko J, Shapiro SM, Tiribelli C.

Trends Mol Med. 2016 Sep;22(9):758-768. doi: 10.1016/j.molmed.2016.07.004. Epub 2016 Aug 8. Review.

PMID:
27515064
40.

A Comprehensive Evaluation of Steroid Metabolism in Women with Intrahepatic Cholestasis of Pregnancy.

Pařízek A, Hill M, Dušková M, Vítek L, Velíková M, Kancheva R, Šimják P, Koucký M, Kokrdová Z, Adamcová K, Černý A, Hájek Z, Stárka L.

PLoS One. 2016 Aug 5;11(8):e0159203. doi: 10.1371/journal.pone.0159203. eCollection 2016.

41.

 Efficacy and safety of ursodeoxycholic acid in patients with intrahepatic cholestasis of pregnancy.

Parízek A, Simják P, Cerný A, Sestinová A, Zdenková A, Hill M, Dusková M, Vlk R, Kokrdová Z, Koucký M, Vítek L.

Ann Hepatol. 2016 Sep-Oct;15(5):757-61. doi: 10.5604/16652681.1212562.

42.

Endocrine effects of duodenal-jejunal exclusion in obese patients with type 2 diabetes mellitus.

Kaválková P, Mráz M, Trachta P, Kloučková J, Cinkajzlová A, Lacinová Z, Haluzíková D, Beneš M, Vlasáková Z, Burda V, Novák D, Petr T, Vítek L, Pelikánová T, Haluzík M.

J Endocrinol. 2016 Oct;231(1):11-22. doi: 10.1530/JOE-16-0206. Epub 2016 Jul 29.

PMID:
27474690
43.

Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells.

Vanova K, Boukalova S, Gbelcova H, Muchova L, Neuzil J, Gurlich R, Ruml T, Vitek L.

BMC Cancer. 2016 May 12;16:309. doi: 10.1186/s12885-016-2343-9.

44.

Diurnal variation in cholesterol 7α-hydroxylase activity is determined by the -203A>C polymorphism of the CYP7A1 gene.

Vlachova M, Blahova T, Lanska V, Leníček M, Pitha J, Vítek L, Kovar J.

Croat Med J. 2016 Apr 23;57(2):111-7.

45.

[Role of bilirubin in the prevention of cardiovascular diseases and cancer].

Vítek L.

Cas Lek Cesk. 2016;155(2):10-4. Review. Czech.

PMID:
27088786
46.

Osteopontin: A non-invasive parameter of portal hypertension and prognostic marker of cirrhosis.

Bruha R, Jachymova M, Petrtyl J, Dvorak K, Lenicek M, Urbanek P, Svestka T, Vitek L.

World J Gastroenterol. 2016 Mar 28;22(12):3441-50. doi: 10.3748/wjg.v22.i12.3441.

47.

The Biological Effects of Bilirubin Photoisomers.

Jasprova J, Dal Ben M, Vianello E, Goncharova I, Urbanova M, Vyroubalova K, Gazzin S, Tiribelli C, Sticha M, Cerna M, Vitek L.

PLoS One. 2016 Feb 1;11(2):e0148126. doi: 10.1371/journal.pone.0148126. eCollection 2016.

48.

Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury.

Říha M, Hašková P, Martin J, Filipský T, Váňová K, Vávrová J, Holečková M, Homola P, Vítek L, Palicka V, Šimůnek T, Mladěnka P.

Oxid Med Cell Longev. 2016;2016:5213532. doi: 10.1155/2016/5213532. Epub 2015 Dec 14.

49.

Gene variants at FTO, 9p21, and 2q36.3 are age-independently associated with myocardial infarction in Czech men.

Hubacek JA, Vrablik M, Dlouha D, Stanek V, Gebauerova M, Adamkova V, Ceska R, Dostálová G, Linhart A, Vitek L, Pitha J.

Clin Chim Acta. 2016 Feb 15;454:119-23. doi: 10.1016/j.cca.2016.01.005. Epub 2016 Jan 7.

PMID:
26772723
50.

The role of bile acids in metabolic regulation.

Vítek L, Haluzík M.

J Endocrinol. 2016 Mar;228(3):R85-96. doi: 10.1530/JOE-15-0469. Epub 2016 Jan 5. Review.

PMID:
26733603

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