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Items: 1 to 50 of 66

1.

Trait-like vulnerability of higher-order cognition and ability to maintain wakefulness during combined sleep restriction and circadian misalignment.

Sprecher KE, Ritchie HK, Burke TM, Depner CM, Smits AN, Dorrestein PC, Fleshner M, Knight R, Lowry CA, Turek FW, Vitaterna MH, Wright KP Jr.

Sleep. 2019 May 9. pii: zsz113. doi: 10.1093/sleep/zsz113. [Epub ahead of print]

PMID:
31070769
2.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
3.

Parkinson's Disease is Associated with Dysregulations of a Dopamine-Modulated Gene Network Relevant to Sleep and Affective Neurobehaviors in the Striatum.

Jiang P, Scarpa JR, Gao VD, Vitaterna MH, Kasarskis A, Turek FW.

Sci Rep. 2019 Mar 18;9(1):4808. doi: 10.1038/s41598-019-41248-4.

4.

Cross-species systems analysis identifies gene networks differentially altered by sleep loss and depression.

Scarpa JR, Jiang P, Gao VD, Fitzpatrick K, Millstein J, Olker C, Gotter A, Winrow CJ, Renger JJ, Kasarskis A, Turek FW, Vitaterna MH.

Sci Adv. 2018 Jul 25;4(7):eaat1294. doi: 10.1126/sciadv.aat1294. eCollection 2018 Jul.

5.

Light/Dark Shifting Promotes Alcohol-Induced Colon Carcinogenesis: Possible Role of Intestinal Inflammatory Milieu and Microbiota.

Bishehsari F, Saadalla A, Khazaie K, Engen PA, Voigt RM, Shetuni BB, Forsyth C, Shaikh M, Vitaterna MH, Turek F, Keshavarzian A.

Int J Mol Sci. 2016 Dec 2;17(12). pii: E2017.

6.

Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease.

Scarpa JR, Jiang P, Losic B, Readhead B, Gao VD, Dudley JT, Vitaterna MH, Turek FW, Kasarskis A.

PLoS Genet. 2016 Jul 8;12(7):e1006137. doi: 10.1371/journal.pgen.1006137. eCollection 2016 Jul.

7.

Dopamine pathway imbalance in mice lacking Magel2, a Prader-Willi syndrome candidate gene.

Luck C, Vitaterna MH, Wevrick R.

Behav Neurosci. 2016 Aug;130(4):448-59. doi: 10.1037/bne0000150. Epub 2016 Jun 2.

PMID:
27254754
8.

Night workers with circadian misalignment are susceptible to alcohol-induced intestinal hyperpermeability with social drinking.

Swanson GR, Gorenz A, Shaikh M, Desai V, Kaminsky T, Van Den Berg J, Murphy T, Raeisi S, Fogg L, Vitaterna MH, Forsyth C, Turek F, Burgess HJ, Keshavarzian A.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G192-201. doi: 10.1152/ajpgi.00087.2016. Epub 2016 May 19.

9.

Altered Body Weight Regulation in CK1ε Null and tau Mutant Mice on Regular Chow and High Fat Diets.

Zhou L, Summa KC, Olker C, Vitaterna MH, Turek FW.

Genet Res Int. 2016;2016:4973242. doi: 10.1155/2016/4973242. Epub 2016 Apr 6.

10.

Multiple classifier systems for automatic sleep scoring in mice.

Gao V, Turek F, Vitaterna M.

J Neurosci Methods. 2016 May 1;264:33-39. doi: 10.1016/j.jneumeth.2016.02.016. Epub 2016 Feb 27.

11.

The Circadian Clock Mutation Promotes Intestinal Dysbiosis.

Voigt RM, Summa KC, Forsyth CB, Green SJ, Engen P, Naqib A, Vitaterna MH, Turek FW, Keshavarzian A.

Alcohol Clin Exp Res. 2016 Feb;40(2):335-47. doi: 10.1111/acer.12943.

12.

Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet.

Kc R, Li X, Forsyth CB, Voigt RM, Summa KC, Vitaterna MH, Tryniszewska B, Keshavarzian A, Turek FW, Meng QJ, Im HJ.

Sci Rep. 2015 Nov 20;5:16896. doi: 10.1038/srep16896.

13.

Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.

Summa KC, Jiang P, Fitzpatrick K, Voigt RM, Bowers SJ, Forsyth CB, Vitaterna MH, Keshavarzian A, Turek FW.

Alcohol Clin Exp Res. 2015 Oct;39(10):1917-29. doi: 10.1111/acer.12834. Epub 2015 Sep 2.

14.

A systems approach identifies networks and genes linking sleep and stress: implications for neuropsychiatric disorders.

Jiang P, Scarpa JR, Fitzpatrick K, Losic B, Gao VD, Hao K, Summa KC, Yang HS, Zhang B, Allada R, Vitaterna MH, Turek FW, Kasarskis A.

Cell Rep. 2015 May 5;11(5):835-48. doi: 10.1016/j.celrep.2015.04.003. Epub 2015 Apr 23.

15.

Environmental disruption of circadian rhythm predisposes mice to osteoarthritis-like changes in knee joint.

Kc R, Li X, Voigt RM, Ellman MB, Summa KC, Vitaterna MH, Keshavarizian A, Turek FW, Meng QJ, Stein GS, van Wijnen AJ, Chen D, Forsyth CB, Im HJ.

J Cell Physiol. 2015 Sep;230(9):2174-2183. doi: 10.1002/jcp.24946.

16.

Validation of video motion-detection scoring of forced swim test in mice.

Gao V, Vitaterna MH, Turek FW.

J Neurosci Methods. 2014 Sep 30;235:59-64. doi: 10.1016/j.jneumeth.2014.06.002. Epub 2014 Jul 1.

17.

Circadian disorganization alters intestinal microbiota.

Voigt RM, Forsyth CB, Green SJ, Mutlu E, Engen P, Vitaterna MH, Turek FW, Keshavarzian A.

PLoS One. 2014 May 21;9(5):e97500. doi: 10.1371/journal.pone.0097500. eCollection 2014.

18.

The circadian clock gene Csnk1e regulates rapid eye movement sleep amount, and nonrapid eye movement sleep architecture in mice.

Zhou L, Bryant CD, Loudon A, Palmer AA, Vitaterna MH, Turek FW.

Sleep. 2014 Apr 1;37(4):785-93, 793A-793C. doi: 10.5665/sleep.3590.

19.

C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.

Kumar V, Kim K, Joseph C, Kourrich S, Yoo SH, Huang HC, Vitaterna MH, de Villena FP, Churchill G, Bonci A, Takahashi JS.

Science. 2013 Dec 20;342(6165):1508-12. doi: 10.1126/science.1245503.

20.

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation.

Summa KC, Voigt RM, Forsyth CB, Shaikh M, Cavanaugh K, Tang Y, Vitaterna MH, Song S, Turek FW, Keshavarzian A.

PLoS One. 2013 Jun 18;8(6):e67102. doi: 10.1371/journal.pone.0067102. Print 2013.

21.

Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.

Shimomura K, Kumar V, Koike N, Kim TK, Chong J, Buhr ED, Whiteley AR, Low SS, Omura C, Fenner D, Owens JR, Richards M, Yoo SH, Hong HK, Vitaterna MH, Bass J, Pletcher MT, Wiltshire T, Hogenesch J, Lowrey PL, Takahashi JS.

Elife. 2013 Apr 9;2:e00426. doi: 10.7554/eLife.00426.

22.

Altered sleep and affect in the neurotensin receptor 1 knockout mouse.

Fitzpatrick K, Winrow CJ, Gotter AL, Millstein J, Arbuzova J, Brunner J, Kasarskis A, Vitaterna MH, Renger JJ, Turek FW.

Sleep. 2012 Jul 1;35(7):949-56. doi: 10.5665/sleep.1958.

23.

Environmental perturbation of the circadian clock disrupts pregnancy in the mouse.

Summa KC, Vitaterna MH, Turek FW.

PLoS One. 2012;7(5):e37668. doi: 10.1371/journal.pone.0037668. Epub 2012 May 23.

24.

Pharmacological validation of candidate causal sleep genes identified in an N2 cross.

Brunner JI, Gotter AL, Millstein J, Garson S, Binns J, Fox SV, Savitz AT, Yang HS, Fitzpatrick K, Zhou L, Owens JR, Webber AL, Vitaterna MH, Kasarskis A, Uebele VN, Turek F, Renger JJ, Winrow CJ.

J Neurogenet. 2011 Dec;25(4):167-81. doi: 10.3109/01677063.2011.628426.

25.

Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids.

Bryant CD, Parker CC, Zhou L, Olker C, Chandrasekaran RY, Wager TT, Bolivar VJ, Loudon AS, Vitaterna MH, Turek FW, Palmer AA.

Neuropsychopharmacology. 2012 Mar;37(4):1026-35. doi: 10.1038/npp.2011.287. Epub 2011 Nov 16.

26.

Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake.

Millstein J, Winrow CJ, Kasarskis A, Owens JR, Zhou L, Summa KC, Fitzpatrick K, Zhang B, Vitaterna MH, Schadt EE, Renger JJ, Turek FW.

Sleep. 2011 Nov 1;34(11):1469-77. doi: 10.5665/sleep.1378.

27.

High-resolution mapping of a novel genetic locus regulating voluntary physical activity in mice.

Yang HS, Shimomura K, Vitaterna MH, Turek FW.

Genes Brain Behav. 2012 Feb;11(1):113-24. doi: 10.1111/j.1601-183X.2011.00737.x. Epub 2011 Nov 17.

28.

Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse.

Arble DM, Vitaterna MH, Turek FW.

PLoS One. 2011;6(9):e25079. doi: 10.1371/journal.pone.0025079. Epub 2011 Sep 19.

29.

Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.

Fenner D, Odili S, Hong HK, Kobayashi Y, Kohsaka A, Siepka SM, Vitaterna MH, Chen P, Zelent B, Grimsby J, Takahashi JS, Matschinsky FM, Bass J.

J Biol Chem. 2011 Nov 11;286(45):39560-72. doi: 10.1074/jbc.M111.269100. Epub 2011 Sep 15.

30.

Molecular neurobiology of circadian rhythms.

Turek FW, Vitaterna MH.

Handb Clin Neurol. 2011;99:951-61. doi: 10.1016/B978-0-444-52007-4.00016-3. No abstract available.

PMID:
21056237
31.

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.

Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J.

Nature. 2010 Jul 29;466(7306):627-31. doi: 10.1038/nature09253.

32.

Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway.

Shimomura K, Lowrey PL, Vitaterna MH, Buhr ED, Kumar V, Hanna P, Omura C, Izumo M, Low SS, Barrett RK, LaRue SI, Green CB, Takahashi JS.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8399-403. doi: 10.1073/pnas.1004368107. Epub 2010 Apr 19.

33.

Ehd4 is required to attain normal prepubertal testis size but dispensable for fertility in male mice.

George M, Rainey MA, Naramura M, Ying G, Harms DW, Vitaterna MH, Doglio L, Crawford SE, Hess RA, Band V, Band H.

Genesis. 2010 May;48(5):328-42. doi: 10.1002/dvg.20620.

34.

Circadian timing of food intake contributes to weight gain.

Arble DM, Bass J, Laposky AD, Vitaterna MH, Turek FW.

Obesity (Silver Spring). 2009 Nov;17(11):2100-2. doi: 10.1038/oby.2009.264. Epub 2009 Sep 3.

35.

Genetic analysis of daily physical activity using a mouse chromosome substitution strain.

Yang HS, Vitaterna MH, Laposky AD, Shimomura K, Turek FW.

Physiol Genomics. 2009 Sep 9;39(1):47-55. doi: 10.1152/physiolgenomics.00066.2009. Epub 2009 Jun 30.

PMID:
19567786
36.

Uncovering the genetic landscape for multiple sleep-wake traits.

Winrow CJ, Williams DL, Kasarskis A, Millstein J, Laposky AD, Yang HS, Mrazek K, Zhou L, Owens JR, Radzicki D, Preuss F, Schadt EE, Shimomura K, Vitaterna MH, Zhang C, Koblan KS, Renger JJ, Turek FW.

PLoS One. 2009;4(4):e5161. doi: 10.1371/journal.pone.0005161. Epub 2009 Apr 10.

37.

Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.

Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, Balannik V, McDearmon EL, Omura C, Lumayag S, Invergo BM, Glawe B, Cantrell DR, Inayat S, Olvera MA, Vessey KA, McCall MA, Maddox D, Morgans CW, Young B, Pletcher MT, Mullins RF, Troy JB, Takahashi JS.

Vis Neurosci. 2007 Jan-Feb;24(1):111-23.

38.

Mania-like behavior induced by disruption of CLOCK.

Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA Jr, McClung CA.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6406-11. Epub 2007 Mar 22.

39.

The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.

Vitaterna MH, Ko CH, Chang AM, Buhr ED, Fruechte EM, Schook A, Antoch MP, Turek FW, Takahashi JS.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9327-32. Epub 2006 Jun 5.

40.

Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice.

Vitaterna MH, Pinto LH, Takahashi JS.

Trends Neurosci. 2006 Apr;29(4):233-40. Epub 2006 Mar 7. Review.

41.

Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.

Moran JL, Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Bjork BC, Li C, Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ, Kucherlapati R, Beier DR.

Genome Res. 2006 Mar;16(3):436-40. Epub 2006 Feb 3.

42.

Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.

Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, McDearmon EL, Fenner D, Lumayag SL, Omura C, Andrews AW, Baker M, Invergo BM, Olvera MA, Heffron E, Mullins RF, Sheffield VC, Stone EM, Takahashi JS.

Vis Neurosci. 2005 Sep-Oct;22(5):619-29.

PMID:
16332273
43.

Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice.

Brzezinski JA 4th, Brown NL, Tanikawa A, Bush RA, Sieving PA, Vitaterna MH, Takahashi JS, Glaser T.

Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2540-51.

44.

Regulation of dopaminergic transmission and cocaine reward by the Clock gene.

McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9377-81. Epub 2005 Jun 20.

45.

Implementing large-scale ENU mutagenesis screens in North America.

Clark AT, Goldowitz D, Takahashi JS, Vitaterna MH, Siepka SM, Peters LL, Frankel WN, Carlson GA, Rossant J, Nadeau JH, Justice MJ.

Genetica. 2004 Sep;122(1):51-64. Review.

46.

Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus.

Pinto LH, Vitaterna MH, Siepka SM, Shimomura K, Lumayag S, Baker M, Fenner D, Mullins RF, Sheffield VC, Stone EM, Heffron E, Takahashi JS.

Vision Res. 2004 Dec;44(28):3335-45.

47.

A genome end-game: understanding gene function in the nervous system.

Bult C, Kibbe WA, Snoddy J, Vitaterna M, Swanson D, Pretel S, Li Y, Hohman MM, Rinchik E, Takahashi JS, Frankel WN, Goldowitz D.

Nat Neurosci. 2004 May;7(5):484-5. No abstract available.

48.

Effects of age on circadian rhythms are similar in wild-type and heterozygous Clock mutant mice.

Kolker DE, Vitaterna MH, Fruechte EM, Takahashi JS, Turek FW.

Neurobiol Aging. 2004 Apr;25(4):517-23.

49.

Depressive-like behavior and stress reactivity are independent traits in a Wistar Kyoto x Fisher 344 cross.

Solberg LC, Ahmadiyeh N, Baum AE, Vitaterna MH, Takahashi JS, Turek FW, Redei EE.

Mol Psychiatry. 2003 Apr;8(4):423-33.

PMID:
12740600
50.

Measurement of hypocretin/orexin content in the mouse brain using an enzyme immunoassay: the effect of circadian time, age and genetic background.

Lin L, Wisor J, Shiba T, Taheri S, Yanai K, Wurts S, Lin X, Vitaterna M, Takahashi J, Lovenberg TW, Koehl M, Uhl G, Nishino S, Mignot E.

Peptides. 2002 Dec;23(12):2203-11.

PMID:
12535700

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