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Items: 19

1.

Bone Marrow-Derived Mesenchymal Stromal Cells (MSCs) Modulate the Inflammatory Character of Alveolar Macrophages from Sarcoidosis Patients.

McClain Caldwell I, Hogden C, Nemeth K, Boyajian M, Krepuska M, Szombath G, MacDonald S, Abshari M, Moss J, Vitale-Cross L, Fontana JR, Mezey E.

J Clin Med. 2020 Jan 19;9(1). pii: E278. doi: 10.3390/jcm9010278.

2.

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.

Wang Z, Wu VH, Allevato MM, Gilardi M, He Y, Luis Callejas-Valera J, Vitale-Cross L, Martin D, Amornphimoltham P, Mcdermott J, Yung BS, Goto Y, Molinolo AA, Sharabi AB, Cohen EEW, Chen Q, Lyons JG, Alexandrov LB, Gutkind JS.

Nat Commun. 2019 Dec 5;10(1):5546. doi: 10.1038/s41467-019-13471-0.

3.

4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer.

Wang Z, Feng X, Molinolo AA, Martin D, Vitale-Cross L, Nohata N, Ando M, Wahba A, Amornphimoltham P, Wu X, Gilardi M, Allevato M, Wu V, Steffen DJ, Tofilon P, Sonenberg N, Califano J, Chen Q, Lippman SM, Gutkind JS.

Cancer Res. 2019 Apr 1;79(7):1438-1450. doi: 10.1158/0008-5472.CAN-18-1220. Epub 2019 Mar 20.

4.

Mesenchymal stromal cells from infants with simple polydactyly modulate immune responses more efficiently than adult mesenchymal stromal cells.

Myneni VD, McClain-Caldwell I, Martin D, Vitale-Cross L, Marko K, Firriolo JM, Labow BI, Mezey E.

Cytotherapy. 2019 Feb;21(2):148-161. doi: 10.1016/j.jcyt.2018.11.008. Epub 2018 Dec 27.

5.

Inhibition of mTOR Signaling and Clinical Activity of Rapamycin in Head and Neck Cancer in a Window of Opportunity Trial.

Day TA, Shirai K, O'Brien PE, Matheus MG, Godwin K, Sood AJ, Kompelli A, Vick JA, Martin D, Vitale-Cross L, Callejas-Varela JL, Wang Z, Wu X, Harismendy O, Molinolo AA, Lippman SM, Van Waes C, Szabo E, Gutkind JS.

Clin Cancer Res. 2019 Feb 15;25(4):1156-1164. doi: 10.1158/1078-0432.CCR-18-2024. Epub 2018 Nov 12.

6.

Immunogenic potential of human bone marrow mesenchymal stromal cells is enhanced by hyperthermia.

McClain-Caldwell I, Vitale-Cross L, Mayer B, Krepuska M, Boyajian M, Myneni V, Martin D; GENOMICS AND COMPUTATIONAL BIOLOGY CORE, Marko K, Nemeth K, Mezey E.

Cytotherapy. 2018 Dec;20(12):1437-1444. doi: 10.1016/j.jcyt.2018.10.002. Epub 2018 Oct 31.

PMID:
30389270
7.

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.

8.

Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia.

Mayer B, Németh K, Krepuska M, Myneni VD, Maric D, Tisdale JF, Hsieh MM, Uchida N, Lee HJ, Nemeth MJ, Holmbeck K, Noguchi CT, Rogers H, Dey S, Hansen A, Hong J, Chow I, Key S, Szalayova I, Pagani J, Markó K, McClain-Caldwell I, Vitale-Cross L, Young WS, Brownstein MJ, Mezey É.

Sci Transl Med. 2017 Nov 29;9(418). pii: eaao1632. doi: 10.1126/scitranslmed.aao1632.

9.

Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo.

Porat-Shliom N, Tietgens AJ, Van Itallie CM, Vitale-Cross L, Jarnik M, Harding OJ, Anderson JM, Gutkind JS, Weigert R, Arias IM.

Hepatology. 2016 Oct;64(4):1317-29. doi: 10.1002/hep.28724. Epub 2016 Jul 28.

10.

Prevention of tumor growth driven by PIK3CA and HPV oncogenes by targeting mTOR signaling with metformin in oral squamous carcinomas expressing OCT3.

Madera D, Vitale-Cross L, Martin D, Schneider A, Molinolo AA, Gangane N, Carey TE, McHugh JB, Komarck CM, Walline HM, William WN Jr, Seethala RR, Ferris RL, Gutkind JS.

Cancer Prev Res (Phila). 2015 Mar;8(3):197-207. doi: 10.1158/1940-6207.CAPR-14-0348. Epub 2015 Feb 13.

11.

The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies.

Martin D, Abba MC, Molinolo AA, Vitale-Cross L, Wang Z, Zaida M, Delic NC, Samuels Y, Lyons JG, Gutkind JS.

Oncotarget. 2014 Oct 15;5(19):8906-23.

12.

mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations.

Wang Z, Martin D, Molinolo AA, Patel V, Iglesias-Bartolome R, Degese MS, Vitale-Cross L, Chen Q, Gutkind JS.

J Natl Cancer Inst. 2014 Aug 5;106(9). pii: dju215. doi: 10.1093/jnci/dju215. Print 2014 Sep.

13.

LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes.

Homolya L, Fu D, Sengupta P, Jarnik M, Gillet JP, Vitale-Cross L, Gutkind JS, Lippincott-Schwartz J, Arias IM.

PLoS One. 2014 Mar 18;9(3):e91921. doi: 10.1371/journal.pone.0091921. eCollection 2014.

14.

Metformin prevents the development of oral squamous cell carcinomas from carcinogen-induced premalignant lesions.

Vitale-Cross L, Molinolo AA, Martin D, Younis RH, Maruyama T, Patel V, Chen W, Schneider A, Gutkind JS.

Cancer Prev Res (Phila). 2012 Apr;5(4):562-73. doi: 10.1158/1940-6207.CAPR-11-0502. Epub 2012 Mar 31.

15.

Parasympathetic innervation maintains epithelial progenitor cells during salivary organogenesis.

Knox SM, Lombaert IM, Reed X, Vitale-Cross L, Gutkind JS, Hoffman MP.

Science. 2010 Sep 24;329(5999):1645-7. doi: 10.1126/science.1192046.

16.

Chemical carcinogenesis models for evaluating molecular-targeted prevention and treatment of oral cancer.

Vitale-Cross L, Czerninski R, Amornphimoltham P, Patel V, Molinolo AA, Gutkind JS.

Cancer Prev Res (Phila). 2009 May;2(5):419-22. doi: 10.1158/1940-6207.CAPR-09-0058. Epub 2009 Apr 28. Review. No abstract available.

17.

Rapid development of salivary gland carcinomas upon conditional expression of K-ras driven by the cytokeratin 5 promoter.

Raimondi AR, Vitale-Cross L, Amornphimoltham P, Gutkind JS, Molinolo A.

Am J Pathol. 2006 May;168(5):1654-65.

18.

Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis.

Vitale-Cross L, Amornphimoltham P, Fisher G, Molinolo AA, Gutkind JS.

Cancer Res. 2004 Dec 15;64(24):8804-7.

19.

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system.

Orsulic S, Li Y, Soslow RA, Vitale-Cross LA, Gutkind JS, Varmus HE.

Cancer Cell. 2002 Feb;1(1):53-62.

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