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Items: 1 to 50 of 156

1.

Fluorescence and morphology of self-assembled nucleobases and their diphenylalanine-hybrid aggregates.

Romanelli A, Avitabile C, Diaferia C, Roviello V, Altamura D, Giannini C, Vitagliano L, Accardo A.

Chemistry. 2019 Sep 30. doi: 10.1002/chem.201902709. [Epub ahead of print]

PMID:
31566814
2.

Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests.

Meccariello A, Salvemini M, Primo P, Hall B, Koskinioti P, Dalíková M, Gravina A, Gucciardino MA, Forlenza F, Gregoriou ME, Ippolito D, Monti SM, Petrella V, Perrotta MM, Schmeing S, Ruggiero A, Scolari F, Giordano E, Tsoumani KT, Marec F, Windbichler N, Arunkumar KP, Bourtzis K, Mathiopoulos KD, Ragoussis J, Vitagliano L, Tu Z, Papathanos PA, Robinson MD, Saccone G.

Science. 2019 Sep 27;365(6460):1457-1460. doi: 10.1126/science.aax1318. Epub 2019 Aug 29.

PMID:
31467189
3.

KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2α.

Pirone L, Smaldone G, Spinelli R, Barberisi M, Beguinot F, Vitagliano L, Miele C, Di Gaetano S, Raciti GA, Pedone E.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug 26;1864(12):158514. doi: 10.1016/j.bbalip.2019.08.010. [Epub ahead of print]

PMID:
31465887
4.

The Structural Versatility of the BTB Domains of KCTD Proteins and Their Recognition of the GABAB Receptor.

Balasco N, Smaldone G, Vitagliano L.

Biomolecules. 2019 Jul 31;9(8). pii: E323. doi: 10.3390/biom9080323.

5.

Molecular basis of the scalp-ear-nipple syndrome unraveled by the characterization of disease-causing KCTD1 mutants.

Smaldone G, Balasco N, Pirone L, Caruso D, Di Gaetano S, Pedone EM, Vitagliano L.

Sci Rep. 2019 Jul 19;9(1):10519. doi: 10.1038/s41598-019-46911-4.

6.

The characterization of Thermotoga maritima Arginine Binding Protein variants demonstrates that minimal local strains have an important impact on protein stability.

Balasco N, Smaldone G, Vigorita M, Del Vecchio P, Graziano G, Ruggiero A, Vitagliano L.

Sci Rep. 2019 Apr 29;9(1):6617. doi: 10.1038/s41598-019-43157-y.

7.

Structure, stability and aggregation propensity of a Ribonuclease A-Onconase chimera.

Esposito L, Donnarumma F, Ruggiero A, Leone S, Vitagliano L, Picone D.

Int J Biol Macromol. 2019 Jul 15;133:1125-1133. doi: 10.1016/j.ijbiomac.2019.04.164. Epub 2019 Apr 24.

PMID:
31026530
8.

Loop size optimization induces a strong thermal stabilization of the thioredoxin fold.

Ruggiero A, Smaldone G, Esposito L, Balasco N, Vitagliano L.

FEBS J. 2019 May;286(9):1752-1764. doi: 10.1111/febs.14767. Epub 2019 Feb 16.

PMID:
30675750
9.

Assembly modes of hexaphenylalanine variants as function of the charge states of their terminal ends.

Diaferia C, Balasco N, Altamura D, Sibillano T, Gallo E, Roviello V, Giannini C, Morelli G, Vitagliano L, Accardo A.

Soft Matter. 2018 Oct 17;14(40):8219-8230. doi: 10.1039/c8sm01441h.

PMID:
30265271
10.

Domain communication in Thermotoga maritima Arginine Binding Protein unraveled through protein dissection.

Smaldone G, Balasco N, Vigorita M, Ruggiero A, Cozzolino S, Berisio R, Del Vecchio P, Graziano G, Vitagliano L.

Int J Biol Macromol. 2018 Nov;119:758-769. doi: 10.1016/j.ijbiomac.2018.07.172. Epub 2018 Jul 29.

PMID:
30059738
11.

Local structural motifs in proteins: Detection and characterization of fragments inserted in helices.

Balasco N, Smaldone G, Ruggiero A, De Simone A, Vitagliano L.

Int J Biol Macromol. 2018 Oct 15;118(Pt B):1924-1930. doi: 10.1016/j.ijbiomac.2018.07.047. Epub 2018 Jul 12.

PMID:
30017977
12.

Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization.

Smaldone G, Berisio R, Balasco N, D'Auria S, Vitagliano L, Ruggiero A.

Biochim Biophys Acta Proteins Proteom. 2018 Sep;1866(9):952-962. doi: 10.1016/j.bbapap.2018.05.016. Epub 2018 May 31.

PMID:
29860047
13.

Intrinsic structural versatility of the highly conserved 412-423 epitope of the Hepatitis C Virus E2 protein.

Balasco N, Barone D, Iaccarino E, Sandomenico A, De Simone A, Ruvo M, Vitagliano L.

Int J Biol Macromol. 2018 Sep;116:620-632. doi: 10.1016/j.ijbiomac.2018.05.055. Epub 2018 May 11.

PMID:
29758309
14.

The essential player in adipogenesis GRP78 is a novel KCTD15 interactor.

Smaldone G, Pirone L, Capolupo A, Vitagliano L, Monti MC, Di Gaetano S, Pedone E.

Int J Biol Macromol. 2018 Aug;115:469-475. doi: 10.1016/j.ijbiomac.2018.04.078. Epub 2018 Apr 14.

PMID:
29665387
15.

Structural Characterization of Self-Assembled Tetra-Tryptophan Based Nanostructures: Variations on a Common Theme.

Diaferia C, Balasco N, Sibillano T, Giannini C, Vitagliano L, Morelli G, Accardo A.

Chemphyschem. 2018 Jul 5;19(13):1635-1642. doi: 10.1002/cphc.201800026. Epub 2018 Apr 23.

PMID:
29542851
16.

Amyloid-Like Fibrillary Morphology Originated by Tyrosine-Containing Aromatic Hexapeptides.

Diaferia C, Balasco N, Sibillano T, Ghosh M, Adler-Abramovich L, Giannini C, Vitagliano L, Morelli G, Accardo A.

Chemistry. 2018 May 7;24(26):6804-6817. doi: 10.1002/chem.201800351. Epub 2018 Apr 26.

PMID:
29504716
17.

The intrinsic flexibility of the aptamer targeting the ribosomal protein S8 is a key factor for the molecular recognition.

Autiero I, Ruvo M, Improta R, Vitagliano L.

Biochim Biophys Acta Gen Subj. 2018 Apr;1862(4):1006-1016. doi: 10.1016/j.bbagen.2018.01.014.

PMID:
29413905
18.

Dissection of Factors Affecting the Variability of the Peptide Bond Geometry and Planarity.

Balasco N, Esposito L, Thind AS, Guarracino MR, Vitagliano L.

Biomed Res Int. 2017;2017:2617629. doi: 10.1155/2017/2617629. Epub 2017 Oct 15.

19.

A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells.

Cimmino I, Lorenzo V, Fiory F, Doti N, Ricci S, Cabaro S, Liotti A, Vitagliano L, Longo M, Miele C, Formisano P, Beguinot F, Ruvo M, Oriente F.

Oncotarget. 2017 May 30;8(42):71845-71858. doi: 10.18632/oncotarget.18286. eCollection 2017 Sep 22.

20.

Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ.

Di Matteo A, Franceschini M, Paiardini A, Grottesi A, Chiarella S, Rocchio S, Di Natale C, Marasco D, Vitagliano L, Travaglini-Allocatelli C, Federici L.

Oncogenesis. 2017 Sep 18;6(9):e379. doi: 10.1038/oncsis.2017.78.

21.

Structural Characterization of PEGylated Hexaphenylalanine Nanostructures Exhibiting Green Photoluminescence Emission.

Diaferia C, Sibillano T, Altamura D, Roviello V, Vitagliano L, Giannini C, Morelli G, Accardo A.

Chemistry. 2017 Oct 9;23(56):14039-14048. doi: 10.1002/chem.201703055. Epub 2017 Sep 12.

PMID:
28782843
22.

Factors affecting the amplitude of the τ angle in proteins: a revisitation.

Balasco N, Esposito L, Vitagliano L.

Acta Crystallogr D Struct Biol. 2017 Jul 1;73(Pt 7):618-625. doi: 10.1107/S2059798317007793. Epub 2017 Jun 28.

PMID:
28695862
23.

Photoluminescent Peptide-Based Nanostructures as FRET Donor for Fluorophore Dye.

Diaferia C, Sibillano T, Giannini C, Roviello V, Vitagliano L, Morelli G, Accardo A.

Chemistry. 2017 Jun 27;23(36):8741-8748. doi: 10.1002/chem.201701381. Epub 2017 Jun 5.

PMID:
28508550
24.

Cardiovascular Risk Stratification in Patients with Metabolic Syndrome Without Diabetes or Cardiovascular Disease: Usefulness of Metabolic Syndrome Severity Score.

Masson W, Epstein T, Huerín M, Lobo LM, Molinero G, Angel A, Masson G, Millán D, De Francesca S, Vitagliano L, Cafferata A, Losada P.

High Blood Press Cardiovasc Prev. 2017 Sep;24(3):297-303. doi: 10.1007/s40292-017-0209-0. Epub 2017 May 13.

PMID:
28502055
25.

Structural Versatility of Hepatitis C Virus Proteins: Implications for the Design of Novel Anti-HCV Intervention Strategies.

Balasco N, Barone D, Sandomenico A, Ruggiero A, Doti N, Berisio R, Ruvo M, Vitagliano L.

Curr Med Chem. 2017 Nov 24;24(36):4081-4101. doi: 10.2174/0929867324666170508105544. Review.

PMID:
28482787
26.

Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin.

Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A.

Sci Rep. 2017 Mar 22;7(1):307. doi: 10.1038/s41598-017-00332-3.

27.

Fine Sampling of the R→T Quaternary-Structure Transition of a Tetrameric Hemoglobin.

Vitagliano L, Mazzarella L, Merlino A, Vergara A.

Chemistry. 2017 Jan 12;23(3):605-613. doi: 10.1002/chem.201603421. Epub 2016 Dec 7.

PMID:
27808442
28.

Hierarchical Analysis of Self-Assembled PEGylated Hexaphenylalanine Photoluminescent Nanostructures.

Diaferia C, Sibillano T, Balasco N, Giannini C, Roviello V, Vitagliano L, Morelli G, Accardo A.

Chemistry. 2016 Nov 7;22(46):16586-16597. doi: 10.1002/chem.201604107. Epub 2016 Oct 5.

PMID:
27706842
29.

Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners.

Pirone L, Smaldone G, Esposito C, Balasco N, Petoukhov MV, Spilotros A, Svergun DI, Di Gaetano S, Vitagliano L, Pedone EM.

Biochimie. 2016 Dec;131:106-114. doi: 10.1016/j.biochi.2016.09.013. Epub 2016 Sep 24.

PMID:
27678190
30.

Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis.

Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R.

J Biomol Struct Dyn. 2017 May;35(6):1322-1330. doi: 10.1080/07391102.2016.1182947. Epub 2016 Jul 15.

31.

The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states.

Smaldone G, Pirone L, Pedone E, Marlovits T, Vitagliano L, Ciccarelli L.

FEBS Lett. 2016 Jun;590(11):1663-71. doi: 10.1002/1873-3468.12203. Epub 2016 May 24.

32.

Proline 235 plays a key role in the regulation of the oligomeric states of Thermotoga maritima Arginine Binding Protein.

Smaldone G, Vigorita M, Ruggiero A, Balasco N, Dattelbaum JD, D'Auria S, Del Vecchio P, Graziano G, Vitagliano L.

Biochim Biophys Acta. 2016 Jul;1864(7):814-24. doi: 10.1016/j.bbapap.2016.04.006. Epub 2016 Apr 14.

PMID:
27087545
33.

The Interacting Domains of PREP1 and p160 are Endowed with a Remarkable Structural Stability.

Lorenzo V, Mascanzoni F, Vitagliano L, Ruvo M, Doti N.

Mol Biotechnol. 2016 May;58(5):328-39. doi: 10.1007/s12033-016-9932-3.

PMID:
26979610
34.

The dynamic properties of the Hepatitis C Virus E2 envelope protein unraveled by molecular dynamics.

Barone D, Balasco N, Autiero I, Vitagliano L.

J Biomol Struct Dyn. 2017 Mar;35(4):805-816. doi: 10.1080/07391102.2016.1162198. Epub 2016 Jul 8.

PMID:
26973093
35.

Generation and Characterization of Monoclonal Antibodies against a Cyclic Variant of Hepatitis C Virus E2 Epitope 412-422.

Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Focà G, Focà A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M.

J Virol. 2016 Jan 27;90(7):3745-59. doi: 10.1128/JVI.02397-15.

36.

The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains.

Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R.

Biochim Biophys Acta. 2016 Feb;1860(2):445-51. doi: 10.1016/j.bbagen.2015.11.001. Epub 2015 Nov 5.

PMID:
26549874
37.

KCTD5 is endowed with large, functionally relevant, interdomain motions.

Barone D, Balasco N, Vitagliano L.

J Biomol Struct Dyn. 2016 Aug;34(8):1725-35. doi: 10.1080/07391102.2015.1090343. Epub 2015 Oct 19.

PMID:
26336981
38.

The determinants of bond angle variability in protein/peptide backbones: A comprehensive statistical/quantum mechanics analysis.

Improta R, Vitagliano L, Esposito L.

Proteins. 2015 Nov;83(11):1973-86. doi: 10.1002/prot.24876. Epub 2015 Sep 22.

PMID:
26264789
39.

Bond distances in polypeptide backbones depend on the local conformation.

Improta R, Vitagliano L, Esposito L.

Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1272-83. doi: 10.1107/S1399004715005507. Epub 2015 May 14.

PMID:
26057667
40.

Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions.

Di Natale C, Scognamiglio PL, Cascella R, Cecchi C, Russo A, Leone M, Penco A, Relini A, Federici L, Di Matteo A, Chiti F, Vitagliano L, Marasco D.

FASEB J. 2015 Sep;29(9):3689-701. doi: 10.1096/fj.14-269522. Epub 2015 May 14.

PMID:
25977257
41.

Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins.

Smaldone G, Pirone L, Balasco N, Di Gaetano S, Pedone EM, Vitagliano L.

PLoS One. 2015 May 14;10(5):e0126808. doi: 10.1371/journal.pone.0126808. eCollection 2015.

42.

Cullin3-BTB interface: a novel target for stapled peptides.

de Paola I, Pirone L, Palmieri M, Balasco N, Esposito L, Russo L, Mazzà D, Di Marcotullio L, Di Gaetano S, Malgieri G, Vitagliano L, Pedone E, Zaccaro L.

PLoS One. 2015 Apr 7;10(4):e0121149. doi: 10.1371/journal.pone.0121149. eCollection 2015.

43.

Cardiovascular risk stratification in overweight or obese patients in primary prevention. Implications for use of statins.

Masson W, Lobo M, Huerín M, Molinero G, Manente D, Pángaro M, Vitagliano L, Zylbersztejn H.

Endocrinol Nutr. 2015 Feb;62(2):83-90. doi: 10.1016/j.endonu.2014.10.006. Epub 2015 Jan 5. English, Spanish.

PMID:
25573227
44.

Structural conversion of the transformer protein RfaH: new insights derived from protein structure prediction and molecular dynamics simulations.

Balasco N, Barone D, Vitagliano L.

J Biomol Struct Dyn. 2015;33(10):2173-9. doi: 10.1080/07391102.2014.994188. Epub 2015 Jan 12.

PMID:
25483894
45.

Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: evidence for the L-to-D inversion of configuration of the catalytic cysteine.

Squeglia F, Ruggiero A, Romano M, Vitagliano L, Berisio R.

Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2295-300. doi: 10.1107/S1399004714013674. Epub 2014 Aug 29.

PMID:
25195744
46.

Comments on structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1.9 Å resolution by P. Ramesh et al. (2013). J. Synchrotron Rad.20, 843-847.

Merlino A, Vergara A, Vitagliano L.

J Synchrotron Radiat. 2014 Jul;21(Pt 4):832-3. doi: 10.1107/S1600577514010170. Epub 2014 Jun 12. No abstract available.

PMID:
24971983
47.

A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima.

Ruggiero A, Dattelbaum JD, Staiano M, Berisio R, D'Auria S, Vitagliano L.

PLoS One. 2014 May 15;9(5):e96560. doi: 10.1371/journal.pone.0096560. eCollection 2014.

48.

Molecular recognition of Cullin3 by KCTDs: insights from experimental and computational investigations.

Balasco N, Pirone L, Smaldone G, Di Gaetano S, Esposito L, Pedone EM, Vitagliano L.

Biochim Biophys Acta. 2014 Jul;1844(7):1289-98. doi: 10.1016/j.bbapap.2014.04.006. Epub 2014 Apr 18.

PMID:
24747150
49.

G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection.

Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D.

Biochim Biophys Acta. 2014 Jun;1840(6):2050-9. doi: 10.1016/j.bbagen.2014.02.017. Epub 2014 Feb 24.

PMID:
24576674
50.

Interplay between peptide bond geometrical parameters in nonglobular structural contexts.

Esposito L, Balasco N, De Simone A, Berisio R, Vitagliano L.

Biomed Res Int. 2013;2013:326914. doi: 10.1155/2013/326914. Epub 2013 Dec 26.

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