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Items: 23

1.

Targeting Cancer Cells and Tumor Microenvironment in Preclinical and Clinical Models of Hodgkin Lymphoma Using the Dual PI3Kδ/γ Inhibitor RP6530.

Locatelli SL, Careddu G, Serio S, Consonni FM, Maeda A, Viswanadha S, Vakkalanka S, Castagna L, Santoro A, Allavena P, Sica A, Carlo-Stella C.

Clin Cancer Res. 2019 Feb 1;25(3):1098-1112. doi: 10.1158/1078-0432.CCR-18-1133. Epub 2018 Oct 23.

PMID:
30352904
2.

Targeting Orai1-mediated store-operated calcium entry by RP4010 for anti-tumor activity in esophagus squamous cell carcinoma.

Cui C, Chang Y, Zhang X, Choi S, Tran H, Penmetsa KV, Viswanadha S, Fu L, Pan Z.

Cancer Lett. 2018 Sep 28;432:169-179. doi: 10.1016/j.canlet.2018.06.006. Epub 2018 Jun 15.

3.

Phase I/II evaluation of RV1001, a novel PI3Kδ inhibitor, in spontaneous canine lymphoma.

Gardner HL, Rippy SB, Bear MD, Cronin KL, Heeb H, Burr H, Cannon CM, Penmetsa KV, Viswanadha S, Vakkalanka S, London CA.

PLoS One. 2018 Apr 24;13(4):e0195357. doi: 10.1371/journal.pone.0195357. eCollection 2018.

4.

Repurposing of a drug scaffold: Identification of novel sila analogues of rimonabant as potent antitubercular agents.

Ramesh R, Shingare RD, Kumar V, Anand A, B S, Veeraraghavan S, Viswanadha S, Ummanni R, Gokhale R, Srinivasa Reddy D.

Eur J Med Chem. 2016 Oct 21;122:723-730. doi: 10.1016/j.ejmech.2016.07.009. Epub 2016 Jul 9.

PMID:
27476117
5.

Simultaneous Quantification of Baricitinib and Methotrexate in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study.

Veeraraghavan S, Thappali SR, Viswanadha S, Vakkalanka S, Rangaswamy M.

Sci Pharm. 2016 Apr-Jun;84(2):347-59. doi: 10.3797/scipharm.1510-08. Epub 2015 Dec 20.

6.

Pharmacodynamic evaluation of RP3128, a novel and potent CRAC channel inhibitor in guinea pig models of allergic asthma.

Sutovska M, Kocmalova M, Franova S, Vakkalanka S, Viswanadha S.

Eur J Pharmacol. 2016 Feb 5;772:62-70. doi: 10.1016/j.ejphar.2015.12.047. Epub 2015 Dec 25.

PMID:
26724844
7.
8.

Design, Synthesis, and Identification of Silicon Incorporated Oxazolidinone Antibiotics with Improved Brain Exposure.

Seetharamsingh B, Ramesh R, Dange SS, Khairnar PV, Singhal S, Upadhyay D, Veeraraghavan S, Viswanadha S, Vakkalanka S, Reddy DS.

ACS Med Chem Lett. 2015 Oct 26;6(11):1105-10. doi: 10.1021/acsmedchemlett.5b00213. eCollection 2015 Nov 12.

9.

Cathepsin D inhibitors as potential therapeutics for breast cancer treatment: Molecular docking and bioevaluation against triple-negative and triple-positive breast cancers.

Anantaraju HS, Battu MB, Viswanadha S, Sriram D, Yogeeswari P.

Mol Divers. 2016 May;20(2):521-35. doi: 10.1007/s11030-015-9645-8. Epub 2015 Nov 13.

PMID:
26563150
10.

Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening.

Pulla VK, Sriram DS, Soni V, Viswanadha S, Sriram D, Yogeeswari P.

Chem Biol Drug Des. 2015 Oct;86(4):881-94. doi: 10.1111/cbdd.12562. Epub 2015 Apr 24.

PMID:
25850461
11.

A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro.

Dinavahi SS, Prasanna R, Dharmarajan S, Perumal Y, Viswanadha S.

Cancer Res Treat. 2015 Oct;47(4):913-20. doi: 10.4143/crt.2014.057. Epub 2015 Jan 2.

12.

Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI-45227 in rat plasma by LC-MS/MS: application to a pharmacokinetic study.

Veeraraghavan S, Viswanadha S, Thappali S, Govindarajulu B, Vakkalanka S, Rangasamy M.

J Pharm Biomed Anal. 2015 Mar 25;107:151-8. doi: 10.1016/j.jpba.2014.11.041. Epub 2014 Dec 25.

PMID:
25594893
13.

Structure-based drug design of small molecule SIRT1 modulators to treat cancer and metabolic disorders.

Pulla VK, Alvala M, Sriram DS, Viswanadha S, Sriram D, Yogeeswari P.

J Mol Graph Model. 2014 Jul;52:46-56. doi: 10.1016/j.jmgm.2014.06.005. Epub 2014 Jun 24.

PMID:
25000096
14.

DDD-028: a potent potential non-opioid, non-cannabinoid analgesic for neuropathic and inflammatory pain.

Rajagopalan P, Tracey H, Chen Z, Bandyopadhyaya A, Veeraraghavan S, Rajagopalan DR, Salvemini D, McPhee I, Viswanadha S, Rajagopalan R.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3088-91. doi: 10.1016/j.bmcl.2014.05.016. Epub 2014 May 14.

PMID:
24863744
15.

Simultaneous quantification of ruxolitinib and nilotinib in rat plasma by LC-MS/MS: application to a pharmacokinetic study.

Veeraraghavan S, Thappali S, Viswanadha S, Chennupati S, Nalla S, Golla M, Vakkalanka S, Rangasamy M.

J Pharm Biomed Anal. 2014 Jun;94:125-31. doi: 10.1016/j.jpba.2014.01.040. Epub 2014 Feb 3.

PMID:
24561338
16.

Simultaneous quantification of idelalisib, fludarabine and lenalidomide in rat plasma by using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass spectrometry.

Veeraraghavan S, Thappali S, Viswanadha S, Nalla S, Chennupati S, Golla M, Vakkalanka S, Rangasamy M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Feb 15;949-950:63-9. doi: 10.1016/j.jchromb.2014.01.001. Epub 2014 Jan 8.

PMID:
24463402
17.

Combined inhibition of PDE4 and PI3Kδ modulates the inflammatory component involved in the progression of chronic obstructive pulmonary disease.

Dinavahi SS, Nyayapathy S, Perumal Y, Dharmarajan S, Viswanadha S.

Drug Res (Stuttg). 2014 Apr;64(4):214-9. doi: 10.1055/s-0033-1355411. Epub 2013 Oct 8.

PMID:
24105104
18.
19.

The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation.

Wojtanik KM, Edgemon K, Viswanadha S, Lindsey B, Haluzik M, Chen W, Poy G, Reitman M, Londos C.

J Lipid Res. 2009 Jun;50(6):1068-79. doi: 10.1194/jlr.M800491-JLR200. Epub 2009 Feb 5.

20.

Determination of lipolysis in isolated primary adipocytes.

Viswanadha S, Londos C.

Methods Mol Biol. 2008;456:299-306. doi: 10.1007/978-1-59745-245-8_22.

PMID:
18516570
21.
22.

Optimized conditions for measuring lipolysis in murine primary adipocytes.

Viswanadha S, Londos C.

J Lipid Res. 2006 Aug;47(8):1859-64. Epub 2006 May 4.

23.

Dose response of milk fat to intravenous administration of the trans-10, cis-12 isomer of conjugated linoleic acid.

Viswanadha S, Giesy JG, Hanson TW, McGuire MA.

J Dairy Sci. 2003 Oct;86(10):3229-36.

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