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Items: 35


The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion.

Noonan MM, Dragan M, Mehta MM, Hess DA, Brackstone M, Tuck AB, Viswakarma N, Rana A, Babwah AV, Wondisford FE, Bhattacharya M.

Oncotarget. 2018 Jul 10;9(53):30034-30052. doi: 10.18632/oncotarget.25682. eCollection 2018 Jul 10.


PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism.

Jia Y, Liu N, Viswakarma N, Sun R, Schipma MJ, Shang M, Thorp EB, Kanwar YS, Thimmapaya B, Reddy JK.

Int J Mol Sci. 2018 May 16;19(5). pii: E1485. doi: 10.3390/ijms19051485.


Involvement of AMP-activated protein kinase and Death Receptor 5 in TRAIL-Berberine-induced apoptosis of cancer cells.

Ke R, Vishnoi K, Viswakarma N, Santha S, Das S, Rana A, Rana B.

Sci Rep. 2018 Apr 3;8(1):5521. doi: 10.1038/s41598-018-23780-x.


Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesis.

Viswakarma N, Nair RS, Sondarva G, Das S, Ibrahimi L, Chen Z, Sinha S, Rana B, Rana A.

Oncotarget. 2017 May 16;8(20):33172-33184. doi: 10.18632/oncotarget.16566.


Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.

Jia Y, Chang HC, Schipma MJ, Liu J, Shete V, Liu N, Sato T, Thorp EB, Barger PM, Zhu YJ, Viswakarma N, Kanwar YS, Ardehali H, Thimmapaya B, Reddy JK.

PLoS One. 2016 Sep 30;11(9):e0164316. doi: 10.1371/journal.pone.0164316. eCollection 2016.


FAK deletion accelerates liver regeneration after two-thirds partial hepatectomy.

Shang N, Arteaga M, Chitsike L, Wang F, Viswakarma N, Breslin P, Qiu W.

Sci Rep. 2016 Sep 28;6:34316. doi: 10.1038/srep34316.


Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.

Jia Y, Chang HC, Schipma MJ, Liu J, Shete V, Liu N, Sato T, Thorp EB, Barger PM, Zhu YJ, Viswakarma N, Kanwar YS, Ardehali H, Thimmapaya B, Reddy JK.

PLoS One. 2016 Aug 22;11(8):e0160755. doi: 10.1371/journal.pone.0160755. eCollection 2016. Erratum in: PLoS One. 2016 Sep 30;11(9):e0164316.


Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4.

Kain V, Kapadia B, Viswakarma N, Seshadri S, Prajapati B, Jena PK, Teja Meda CL, Subramanian M, Kaimal Suraj S, Kumar ST, Prakash Babu P, Thimmapaya B, Reddy JK, Parsa KV, Misra P.

Sci Rep. 2015 Oct 15;5:15197. doi: 10.1038/srep15197.


Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-Troglitazone-induced Apoptosis in Prostate Cancer Cells Involve AMP-activated Protein Kinase.

Santha S, Viswakarma N, Das S, Rana A, Rana B.

J Biol Chem. 2015 Sep 4;290(36):21865-75. doi: 10.1074/jbc.M115.663526. Epub 2015 Jul 21.


Human Epidermal Growth Factor Receptor 2 (HER2) Impedes MLK3 Kinase Activity to Support Breast Cancer Cell Survival.

Das S, Sondarva G, Viswakarma N, Nair RS, Osipo C, Tzivion G, Rana B, Rana A.

J Biol Chem. 2015 Aug 28;290(35):21705-12. doi: 10.1074/jbc.M115.655563. Epub 2015 Jul 7.


Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis.

Jia Y, Viswakarma N, Reddy JK.

Gene Expr. 2014;16(2):63-75. doi: 10.3727/105221614X13919976902219. Review.


ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.

Kapadia B, Viswakarma N, Parsa KV, Kain V, Behera S, Suraj SK, Babu PP, Kar A, Panda S, Zhu YJ, Jia Y, Thimmapaya B, Reddy JK, Misra P.

PLoS One. 2013 Dec 17;8(12):e83787. doi: 10.1371/journal.pone.0083787. eCollection 2013.


Mixed Lineage Kinase-c-Jun N-Terminal Kinase Axis: A Potential Therapeutic Target in Cancer.

Rana A, Rana B, Mishra R, Sondarva G, Rangasamy V, Das S, Viswakarma N, Kanthasamy A.

Genes Cancer. 2013 Sep;4(9-10):334-41. doi: 10.1177/1947601913485415. Review.


The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase.

Viswakarma N, Jia Y, Bai L, Gao Q, Lin B, Zhang X, Misra P, Rana A, Jain S, Gonzalez FJ, Zhu YJ, Thimmapaya B, Reddy JK.

J Biol Chem. 2013 Sep 27;288(39):27898-911. doi: 10.1074/jbc.M113.486696. Epub 2013 Aug 13.


Peroxisome proliferator-activated receptor-α signaling in hepatocarcinogenesis.

Misra P, Viswakarma N, Reddy JK.

Subcell Biochem. 2013;69:77-99. doi: 10.1007/978-94-007-6889-5_5. Review.


Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.

Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK.

Mech Dev. 2012 Sep-Dec;129(9-12):193-207. doi: 10.1016/j.mod.2012.08.002. Epub 2012 Sep 7.


Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.

Huang J, Jia Y, Fu T, Viswakarma N, Bai L, Rao MS, Zhu Y, Borensztajn J, Reddy JK.

FASEB J. 2012 Feb;26(2):628-38. doi: 10.1096/fj.11-194019. Epub 2011 Oct 18.


Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice.

Huang J, Viswakarma N, Yu S, Jia Y, Bai L, Vluggens A, Cherkaoui-Malki M, Khan M, Singh I, Yang G, Rao MS, Borensztajn J, Reddy JK.

Am J Pathol. 2011 Aug;179(2):703-13. doi: 10.1016/j.ajpath.2011.04.030. Epub 2011 Jun 12.


Transcriptional and post-translational modulation of myo-inositol oxygenase by high glucose and related pathobiological stresses.

Nayak B, Kondeti VK, Xie P, Lin S, Viswakarma N, Raparia K, Kanwar YS.

J Biol Chem. 2011 Aug 5;286(31):27594-611. doi: 10.1074/jbc.M110.217141. Epub 2011 Jun 7.


Transcription coactivator mediator subunit MED1 is required for the development of fatty liver in the mouse.

Bai L, Jia Y, Viswakarma N, Huang J, Vluggens A, Wolins NE, Jafari N, Rao MS, Borensztajn J, Yang G, Reddy JK.

Hepatology. 2011 Apr;53(4):1164-74. doi: 10.1002/hep.24155. Erratum in: Hepatology. 2011 Sep 2;54(3):1114.


PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex.

Pyper SR, Viswakarma N, Jia Y, Zhu YJ, Fondell JD, Reddy JK.

PPAR Res. 2010;2010. pii: 173907. doi: 10.1155/2010/173907. Epub 2010 Sep 5.


Coactivators in PPAR-Regulated Gene Expression.

Viswakarma N, Jia Y, Bai L, Vluggens A, Borensztajn J, Xu J, Reddy JK.

PPAR Res. 2010;2010. pii: 250126. doi: 10.1155/2010/250126. Epub 2010 Aug 5.


PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.

Pyper SR, Viswakarma N, Yu S, Reddy JK.

Nucl Recept Signal. 2010 Apr 16;8:e002. doi: 10.1621/nrs.08002. Review.


Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected].

Vluggens A, Andreoletti P, Viswakarma N, Jia Y, Matsumoto K, Kulik W, Khan M, Huang J, Guo D, Yu S, Sarkar J, Singh I, Rao MS, Wanders RJ, Reddy JK, Cherkaoui-Malki M.

Lab Invest. 2010 May;90(5):696-708. doi: 10.1038/labinvest.2010.46. Epub 2010 Mar 1. Erratum in: Lab Invest. 2010 May;90(5):808.


Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse.

Matsumoto K, Huang J, Viswakarma N, Bai L, Jia Y, Zhu YT, Yang G, Borensztajn J, Rao MS, Zhu YJ, Reddy JK.

Carcinogenesis. 2010 Feb;31(2):318-25. doi: 10.1093/carcin/bgp306. Epub 2009 Dec 9.


Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Hall AM, Brunt EM, Chen Z, Viswakarma N, Reddy JK, Wolins NE, Finck BN.

J Lipid Res. 2010 Mar;51(3):554-63. doi: 10.1194/jlr.M000976. Epub 2009 Sep 11.


Transcriptional regulation of Cidea, mitochondrial cell death-inducing DNA fragmentation factor alpha-like effector A, in mouse liver by peroxisome proliferator-activated receptor alpha and gamma.

Viswakarma N, Yu S, Naik S, Kashireddy P, Matsumoto K, Sarkar J, Surapureddi S, Jia Y, Rao MS, Reddy JK.

J Biol Chem. 2007 Jun 22;282(25):18613-24. Epub 2007 Apr 26.


Critical role for transcription coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARalpha ligand-induced liver tumor development.

Matsumoto K, Yu S, Jia Y, Ahmed MR, Viswakarma N, Sarkar J, Kashireddy PV, Rao MS, Karpus W, Gonzalez FJ, Reddy JK.

J Biol Chem. 2007 Jun 8;282(23):17053-60. Epub 2007 Apr 16.


Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver.

Guo D, Sarkar J, Ahmed MR, Viswakarma N, Jia Y, Yu S, Sambasiva Rao M, Reddy JK.

Biochem Biophys Res Commun. 2006 Aug 25;347(2):485-95. Epub 2006 Jun 30.


PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.

Surapureddi S, Viswakarma N, Yu S, Guo D, Rao MS, Reddy JK.

Biochem Biophys Res Commun. 2006 May 5;343(2):535-43. Epub 2006 Mar 9.


Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver.

Yu S, Viswakarma N, Batra SK, Sambasiva Rao M, Reddy JK.

Biochimie. 2004 Nov;86(11):743-61.


Chitinase-mediated inhibitory activity of Brassica transgenic on growth of Alternaria brassicae.

Mondal KK, Chatterjee SC, Viswakarma N, Bhattacharya RC, Grover A.

Curr Microbiol. 2003 Sep;47(3):171-3.


Agrobacterium-mediated transformation of cauliflower: optimization of protocol and development of Bt-transgenic cauliflower.

Chakrabarty R, Viswakarma N, Bhat SR, Kirti PB, Singh BD, Chopra VL.

J Biosci. 2002 Sep;27(5):495-502.

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