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Items: 1 to 50 of 52

1.

Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion.

Gunalan K, Sá JM, Moraes Barros RR, Anzick SL, Caleon RL, Mershon JP, Kanakabandi K, Paneru M, Virtaneva K, Martens C, Barnwell JW, Ribeiro JM, Miller LH.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7053-7061. doi: 10.1073/pnas.1818485116. Epub 2019 Mar 14.

2.

Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis.

Cornish JP, Moore IN, Perry DL, Lara A, Minai M, Promeneur D, Hagen KR, Virtaneva K, Paneru M, Buechler CR, O'Connor DH, Bailey AL, Cooper K, Mazur S, Bernbaum JG, Pettitt J, Jahrling PB, Kuhn JH, Johnson RF.

Viruses. 2019 Jan 15;11(1). pii: E67. doi: 10.3390/v11010067.

3.

Comparative Transcriptomic Response of Primary and Immortalized Macrophages to Murine Norovirus Infection.

Levenson EA, Martens C, Kanakabandi K, Turner CV, Virtaneva K, Paneru M, Ricklefs S, Sosnovtsev SV, Johnson JA, Porcella SF, Green KY.

J Immunol. 2018 Jun 15;200(12):4157-4169. doi: 10.4049/jimmunol.1700384. Epub 2018 May 7.

4.

Peromyscus leucopus mouse brain transcriptome response to Powassan virus infection.

Mlera L, Meade-White K, Dahlstrom E, Baur R, Kanakabandi K, Virtaneva K, Porcella SF, Bloom ME.

J Neurovirol. 2018 Feb;24(1):75-87. doi: 10.1007/s13365-017-0596-y. Epub 2017 Nov 16.

5.

Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial.

Meissner EG, McLaughlin M, Matthews L, Gharib AM, Wood BJ, Levy E, Sinkus R, Virtaneva K, Sturdevant D, Martens C, Porcella SF, Goodman ZD, Kanwar B, Myers RP, Subramanian M, Hadigan C, Masur H, Kleiner DE, Heller T, Kottilil S, Kovacs JA, Morse CG.

Liver Int. 2016 Dec;36(12):1783-1792. doi: 10.1111/liv.13177. Epub 2016 Jul 6.

6.

Achieving sustained virologic response after interferon-free hepatitis C virus treatment correlates with hepatic interferon gene expression changes independent of cirrhosis.

Meissner EG, Kohli A, Virtaneva K, Sturdevant D, Martens C, Porcella SF, McHutchison JG, Masur H, Kottilil S.

J Viral Hepat. 2016 Jul;23(7):496-505. doi: 10.1111/jvh.12510. Epub 2016 Feb 3.

7.

Simultaneous Host-Pathogen Transcriptome Analysis during Granulibacter bethesdensis Infection of Neutrophils from Healthy Subjects and Patients with Chronic Granulomatous Disease.

Greenberg DE, Sturdevant DE, Marshall-Batty KR, Chu J, Pettinato AM, Virtaneva K, Lane J, Geller BL, Porcella SF, Gallin JI, Holland SM, Zarember KA.

Infect Immun. 2015 Nov;83(11):4277-92. doi: 10.1128/IAI.00778-15. Epub 2015 Aug 17.

8.

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function.

Portugal S, Tipton CM, Sohn H, Kone Y, Wang J, Li S, Skinner J, Virtaneva K, Sturdevant DE, Porcella SF, Doumbo OK, Doumbo S, Kayentao K, Ongoiba A, Traore B, Sanz I, Pierce SK, Crompton PD.

Elife. 2015 May 8;4. doi: 10.7554/eLife.07218.

9.

Transcriptional profiling of human epithelial cells infected with plasmid-bearing and plasmid-deficient Chlamydia trachomatis.

Porcella SF, Carlson JH, Sturdevant DE, Sturdevant GL, Kanakabandi K, Virtaneva K, Wilder H, Whitmire WM, Song L, Caldwell HD.

Infect Immun. 2015 Feb;83(2):534-43. doi: 10.1128/IAI.02764-14. Epub 2014 Nov 17.

10.

Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome.

Tchitchek N, Safronetz D, Rasmussen AL, Martens C, Virtaneva K, Porcella SF, Feldmann H, Ebihara H, Katze MG.

PLoS One. 2014 Nov 14;9(11):e112617. doi: 10.1371/journal.pone.0112617. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0117958.

11.

Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.

Meissner EG, Wu D, Osinusi A, Bon D, Virtaneva K, Sturdevant D, Porcella S, Wang H, Herrmann E, McHutchison J, Suffredini AF, Polis M, Hewitt S, Prokunina-Olsson L, Masur H, Fauci AS, Kottilil S.

J Clin Invest. 2014 Aug;124(8):3352-63. doi: 10.1172/JCI75938. Epub 2014 Jul 1.

12.

Exposure-dependent control of malaria-induced inflammation in children.

Portugal S, Moebius J, Skinner J, Doumbo S, Doumtabe D, Kone Y, Dia S, Kanakabandi K, Sturdevant DE, Virtaneva K, Porcella SF, Li S, Doumbo OK, Kayentao K, Ongoiba A, Traore B, Crompton PD.

PLoS Pathog. 2014 Apr 17;10(4):e1004079. doi: 10.1371/journal.ppat.1004079. eCollection 2014 Apr.

13.

Transcriptome analysis identifies Bacillus anthracis genes that respond to CO2 through an AtxA-dependent mechanism.

McKenzie AT, Pomerantsev AP, Sastalla I, Martens C, Ricklefs SM, Virtaneva K, Anzick S, Porcella SF, Leppla SH.

BMC Genomics. 2014 Mar 25;15:229. doi: 10.1186/1471-2164-15-229.

14.

Plasmid-mediated transformation tropism of chlamydial biovars.

Song L, Carlson JH, Zhou B, Virtaneva K, Whitmire WM, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD.

Pathog Dis. 2014 Mar;70(2):189-93. doi: 10.1111/2049-632X.12104. Epub 2013 Nov 11.

15.

miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation.

Kelada S, Sethupathy P, Okoye IS, Kistasis E, Czieso S, White SD, Chou D, Martens C, Ricklefs SM, Virtaneva K, Sturdevant DE, Porcella SF, Belkaid Y, Wynn TA, Wilson MS.

PLoS Pathog. 2013;9(6):e1003451. doi: 10.1371/journal.ppat.1003451. Epub 2013 Jun 27.

16.

Effect of the leptin receptor Q223R polymorphism on the host transcriptome following infection with Entamoeba histolytica.

Mackey-Lawrence NM, Guo X, Sturdevant DE, Virtaneva K, Hernandez MM, Houpt E, Sher A, Porcella SF, Petri WA Jr.

Infect Immun. 2013 May;81(5):1460-70. doi: 10.1128/IAI.01383-12. Epub 2013 Feb 19. Erratum in: Infect Immun. 2013 Nov;81(11):4322.

17.

Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes.

Song L, Carlson JH, Whitmire WM, Kari L, Virtaneva K, Sturdevant DE, Watkins H, Zhou B, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD.

Infect Immun. 2013 Mar;81(3):636-44. doi: 10.1128/IAI.01305-12. Epub 2013 Jan 14.

18.

Profound amplification of pathogenic murine polytropic retrovirus release from coinfected cells.

Rosenke K, Lavignon M, Malik F, Kolokithas A, Hendrick D, Virtaneva K, Peterson K, Evans LH.

J Virol. 2012 Jul;86(13):7241-8. doi: 10.1128/JVI.00225-12. Epub 2012 Apr 18.

19.

Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques.

Rockx B, Feldmann F, Brining D, Gardner D, LaCasse R, Kercher L, Long D, Rosenke R, Virtaneva K, Sturdevant DE, Porcella SF, Mattoon J, Parnell M, Baric RS, Feldmann H.

PLoS One. 2011 Apr 20;6(4):e18558. doi: 10.1371/journal.pone.0018558.

20.

Transcriptomic and innate immune responses to Yersinia pestis in the lymph node during bubonic plague.

Comer JE, Sturdevant DE, Carmody AB, Virtaneva K, Gardner D, Long D, Rosenke R, Porcella SF, Hinnebusch BJ.

Infect Immun. 2010 Dec;78(12):5086-98. doi: 10.1128/IAI.00256-10. Epub 2010 Sep 27.

21.

Recurrent Granulibacter bethesdensis infections and chronic granulomatous disease.

Greenberg DE, Shoffner AR, Zelazny AM, Fenster ME, Zarember KA, Stock F, Ding L, Marshall-Batty KR, Wasserman RL, Welch DF, Kanakabandi K, Sturdevant DE, Virtaneva K, Porcella SF, Murray PR, Malech HL, Holland SM.

Emerg Infect Dis. 2010 Sep;16(9):1341-8. doi: 10.3201/eid1609.091800.

22.

Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus.

Shea PR, Virtaneva K, Kupko JJ 3rd, Porcella SF, Barry WT, Wright FA, Kobayashi SD, Carmody A, Ireland RM, Sturdevant DE, Ricklefs SM, Babar I, Johnson CA, Graham MR, Gardner DJ, Bailey JR, Parnell MJ, Deleo FR, Musser JM.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4693-8. doi: 10.1073/pnas.0906384107. Epub 2010 Feb 23.

23.

Host-microbe interaction systems biology: lifecycle transcriptomics and comparative genomics.

Sturdevant DE, Virtaneva K, Martens C, Bozinov D, Ogundare O, Castro N, Kanakabandi K, Beare PA, Omsland A, Carlson JH, Kennedy AD, Heinzen RA, Celli J, Greenberg DE, DeLeo FR, Porcella SF.

Future Microbiol. 2010 Feb;5(2):205-19. doi: 10.2217/fmb.09.125. Review. Erratum in: Future Microbiol. 2010 Mar;5(3):526. Ohmsland, Anders [corrected to Omsland, Anders].

24.

Induction of Salmonella pathogenicity island 1 under different growth conditions can affect Salmonella-host cell interactions in vitro.

Ibarra JA, Knodler LA, Sturdevant DE, Virtaneva K, Carmody AB, Fischer ER, Porcella SF, Steele-Mortimer O.

Microbiology. 2010 Apr;156(Pt 4):1120-33. doi: 10.1099/mic.0.032896-0. Epub 2009 Dec 24.

25.

Limited transcriptional responses of Rickettsia rickettsii exposed to environmental stimuli.

Ellison DW, Clark TR, Sturdevant DE, Virtaneva K, Hackstadt T.

PLoS One. 2009;4(5):e5612. doi: 10.1371/journal.pone.0005612. Epub 2009 May 19.

26.

Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages.

Wehrly TD, Chong A, Virtaneva K, Sturdevant DE, Child R, Edwards JA, Brouwer D, Nair V, Fischer ER, Wicke L, Curda AJ, Kupko JJ 3rd, Martens C, Crane DD, Bosio CM, Porcella SF, Celli J.

Cell Microbiol. 2009 Jul;11(7):1128-50. doi: 10.1111/j.1462-5822.2009.01316.x. Epub 2009 Mar 18.

27.

Host cell-free growth of the Q fever bacterium Coxiella burnetii.

Omsland A, Cockrell DC, Howe D, Fischer ER, Virtaneva K, Sturdevant DE, Porcella SF, Heinzen RA.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4430-4. doi: 10.1073/pnas.0812074106. Epub 2009 Feb 25.

28.

Mobilization of endogenous retroviruses in mice after infection with an exogenous retrovirus.

Evans LH, Alamgir AS, Owens N, Weber N, Virtaneva K, Barbian K, Babar A, Malik F, Rosenke K.

J Virol. 2009 Mar;83(6):2429-35. doi: 10.1128/JVI.01926-08. Epub 2008 Dec 30.

29.

The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor.

Carlson JH, Whitmire WM, Crane DD, Wicke L, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Porcella SF, Martinez-Orengo N, Heinzen RA, Kari L, Caldwell HD.

Infect Immun. 2008 Jun;76(6):2273-83. doi: 10.1128/IAI.00102-08. Epub 2008 Mar 17.

30.

Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa.

Ellison DW, Clark TR, Sturdevant DE, Virtaneva K, Porcella SF, Hackstadt T.

Infect Immun. 2008 Feb;76(2):542-50. Epub 2007 Nov 19.

31.

Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis.

Greenberg DE, Porcella SF, Zelazny AM, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Barbian KD, Babar A, Dorward DW, Holland SM.

J Bacteriol. 2007 Dec;189(23):8727-36. Epub 2007 Sep 7.

32.

Analysis of the transcriptome of group A Streptococcus in mouse soft tissue infection.

Graham MR, Virtaneva K, Porcella SF, Gardner DJ, Long RD, Welty DM, Barry WT, Johnson CA, Parkins LD, Wright FA, Musser JM.

Am J Pathol. 2006 Sep;169(3):927-42.

33.

Adaptive response of Yersinia pestis to extracellular effectors of innate immunity during bubonic plague.

Sebbane F, Lemaître N, Sturdevant DE, Rebeil R, Virtaneva K, Porcella SF, Hinnebusch BJ.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11766-71. Epub 2006 Jul 24.

34.

In vivo interactions of ecotropic and polytropic murine leukemia viruses in mixed retrovirus infections.

Evans LH, Lavignon M, Peterson K, Hasenkrug K, Robertson S, Malik F, Virtaneva K.

J Virol. 2006 May;80(10):4748-57.

35.

Genetic diversity of the Q fever agent, Coxiella burnetii, assessed by microarray-based whole-genome comparisons.

Beare PA, Samuel JE, Howe D, Virtaneva K, Porcella SF, Heinzen RA.

J Bacteriol. 2006 Apr;188(7):2309-24.

36.

Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events.

Sumby P, Porcella SF, Madrigal AG, Barbian KD, Virtaneva K, Ricklefs SM, Sturdevant DE, Graham MR, Vuopio-Varkila J, Hoe NP, Musser JM.

J Infect Dis. 2005 Sep 1;192(5):771-82. Epub 2005 Jul 29.

PMID:
16088826
37.

Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques.

Virtaneva K, Porcella SF, Graham MR, Ireland RM, Johnson CA, Ricklefs SM, Babar I, Parkins LD, Romero RA, Corn GJ, Gardner DJ, Bailey JR, Parnell MJ, Musser JM.

Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):9014-9. Epub 2005 Jun 14.

38.

Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategies.

Graham MR, Virtaneva K, Porcella SF, Barry WT, Gowen BB, Johnson CR, Wright FA, Musser JM.

Am J Pathol. 2005 Feb;166(2):455-65.

39.

Group A Streptococcus gene expression in humans and cynomolgus macaques with acute pharyngitis.

Virtaneva K, Graham MR, Porcella SF, Hoe NP, Su H, Graviss EA, Gardner TJ, Allison JE, Lemon WJ, Bailey JR, Parnell MJ, Musser JM.

Infect Immun. 2003 Apr;71(4):2199-207.

40.

Genome-wide protective response used by group A Streptococcus to evade destruction by human polymorphonuclear leukocytes.

Voyich JM, Sturdevant DE, Braughton KR, Kobayashi SD, Lei B, Virtaneva K, Dorward DW, Musser JM, DeLeo FR.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1996-2001. Epub 2003 Feb 6.

41.

Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling.

Graham MR, Smoot LM, Migliaccio CA, Virtaneva K, Sturdevant DE, Porcella SF, Federle MJ, Adams GJ, Scott JR, Musser JM.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13855-60. Epub 2002 Oct 7.

42.

Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics.

Virtaneva K, Wright FA, Tanner SM, Yuan B, Lemon WJ, Caligiuri MA, Bloomfield CD, de La Chapelle A, Krahe R.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1124-9.

43.

Characterization of the cystatin B gene promoter harboring the dodecamer repeat expanded in progressive myoclonus epilepsy, EPM1.

Alakurtti K, Virtaneva K, Joensuu T, Palvimo JJ, Lehesjoki AE.

Gene. 2000 Jan 25;242(1-2):65-73.

PMID:
10721698
44.

The minisatellite expansion mutation in EPM1: resolution of an initial discrepancy. Mutatations in brief no. 186. Online.

Virtaneva K, Paulin L, Krahe R, de la Chapelle A, Lehesjoki AE.

Hum Mutat. 1998;12(3):218.

PMID:
10660338
45.

Unstable minisatellite expansion causing recessively inherited myoclonus epilepsy, EPM1.

Virtaneva K, D'Amato E, Miao J, Koskiniemi M, Norio R, Avanzini G, Franceschetti S, Michelucci R, Tassinari CA, Omer S, Pennacchio LA, Myers RM, Dieguez-Lucena JL, Krahe R, de la Chapelle A, Lehesjoki AE.

Nat Genet. 1997 Apr;15(4):393-6.

PMID:
9090386
46.

Progressive myoclonus epilepsy EPM1 locus maps to a 175-kb interval in distal 21q.

Virtaneva K, Miao J, Träskelin AL, Stone N, Warrington JA, Weissenbach J, Myers RM, Cox DR, Sistonen P, de la Chapelle A, et al.

Am J Hum Genet. 1996 Jun;58(6):1247-53.

47.

Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1)

Pennacchio LA, Lehesjoki AE, Stone NE, Willour VL, Virtaneva K, Miao J, D'Amato E, Ramirez L, Faham M, Koskiniemi M, Warrington JA, Norio R, de la Chapelle A, Cox DR, Myers RM.

Science. 1996 Mar 22;271(5256):1731-4.

PMID:
8596935
48.

Expression and characterization of a B cell growth promoting polypeptide derived from the 12 kDa B cell growth factor gene (BCGF 1).

Kovanen PE, Virtaneva K, Harju L, Kantor C, Gahmberg CG, Timonen T.

FEBS Lett. 1995 Mar 20;361(2-3):233-7.

49.

BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.

Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K.

Oncogene. 1994 Dec;9(12):3683-8.

PMID:
7970727
50.

Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins.

Virtaneva KI, Emi N, Marken JS, Aruffo A, Jones C, Spurr NK, Schröder JP.

Immunogenetics. 1994;39(5):329-34.

PMID:
8168850

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