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Items: 1 to 50 of 55

1.

T-blocker: a simple and robust probe-free quantitative PCR assay to detect somatic mutations down to 0.1% frequency.

Kim H, Ruby AE, Shandilya HG, Virmani AK, Rahman N, Strange CM, Huuskonen J.

Biotechniques. 2018 Oct;65(4):205-210. doi: 10.2144/btn-2018-0111.

2.

Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers.

Zöchbauer-Müller S, Lam S, Toyooka S, Virmani AK, Toyooka KO, Seidl S, Minna JD, Gazdar AF.

Int J Cancer. 2003 Nov 20;107(4):612-6.

3.

Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms.

Rathi A, Virmani AK, Harada K, Timmons CF, Miyajima K, Hay RJ, Mastrangelo D, Maitra A, Tomlinson GE, Gazdar AF.

Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3674-8.

4.

Tumor suppressor genes in lung cancer.

Virmani AK, Gazdar AF.

Methods Mol Biol. 2003;222:97-115. Review. No abstract available.

PMID:
12710682
5.

Frequent hypermethylation of the 5' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer.

Corn PG, Summers MK, Fogt F, Virmani AK, Gazdar AF, Halazonetis TD, El-Deiry WS.

Carcinogenesis. 2003 Jan;24(1):47-51.

PMID:
12538348
6.

DNA methylation profiles of lung tumors.

Toyooka S, Toyooka KO, Maruyama R, Virmani AK, Girard L, Miyajima K, Harada K, Ariyoshi Y, Takahashi T, Sugio K, Brambilla E, Gilcrease M, Minna JD, Gazdar AF.

Mol Cancer Ther. 2001 Nov;1(1):61-7.

7.

Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer.

Toyooka S, Maruyama R, Toyooka KO, McLerran D, Feng Z, Fukuyama Y, Virmani AK, Zochbauer-Muller S, Tsukuda K, Sugio K, Shimizu N, Shimizu K, Lee H, Chen CY, Fong KM, Gilcrease M, Roth JA, Minna JD, Gazdar AF.

Int J Cancer. 2003 Jan 10;103(2):153-60.

8.

Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women.

Rathi A, Virmani AK, Schorge JO, Elias KJ, Maruyama R, Minna JD, Mok SC, Girard L, Fishman DA, Gazdar AF.

Clin Cancer Res. 2002 Nov;8(11):3324-31.

9.

Hierarchical clustering of lung cancer cell lines using DNA methylation markers.

Virmani AK, Tsou JA, Siegmund KD, Shen LY, Long TI, Laird PW, Gazdar AF, Laird-Offringa IA.

Cancer Epidemiol Biomarkers Prev. 2002 Mar;11(3):291-7.

10.

Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features.

Maruyama R, Toyooka S, Toyooka KO, Virmani AK, Zöchbauer-Müller S, Farinas AJ, Minna JD, McConnell J, Frenkel EP, Gazdar AF.

Clin Cancer Res. 2002 Feb;8(2):514-9.

11.

Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features.

Maruyama R, Toyooka S, Toyooka KO, Harada K, Virmani AK, Zöchbauer-Müller S, Farinas AJ, Vakar-Lopez F, Minna JD, Sagalowsky A, Czerniak B, Gazdar AF.

Cancer Res. 2001 Dec 15;61(24):8659-63.

12.

Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas.

Virmani AK, Rathi A, Sathyanarayana UG, Padar A, Huang CX, Cunnigham HT, Farinas AJ, Milchgrub S, Euhus DM, Gilcrease M, Herman J, Minna JD, Gazdar AF.

Clin Cancer Res. 2001 Jul;7(7):1998-2004.

13.

High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss.

Maitra A, Wistuba II, Washington C, Virmani AK, Ashfaq R, Milchgrub S, Gazdar AF, Minna JD.

Am J Pathol. 2001 Jul;159(1):119-30.

14.

Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.

Fisher MJ, Virmani AK, Wu L, Aplenc R, Harper JC, Powell SM, Rebbeck TR, Sidransky D, Gazdar AF, El-Deiry WS.

Clin Cancer Res. 2001 Jun;7(6):1688-97.

15.

Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas.

Toyooka KO, Toyooka S, Virmani AK, Sathyanarayana UG, Euhus DM, Gilcrease M, Minna JD, Gazdar AF.

Cancer Res. 2001 Jun 1;61(11):4556-60.

16.

5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.

Zöchbauer-Müller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF, Minna JD.

Cancer Res. 2001 May 1;61(9):3581-5.

17.

Aberrant methylation during cervical carcinogenesis.

Virmani AK, Muller C, Rathi A, Zoechbauer-Mueller S, Mathis M, Gazdar AF.

Clin Cancer Res. 2001 Mar;7(3):584-9.

18.

Dendritic cells transduced with full-length wild-type p53 generate antitumor cytotoxic T lymphocytes from peripheral blood of cancer patients.

Nikitina EY, Clark JI, Van Beynen J, Chada S, Virmani AK, Carbone DP, Gabrilovich DI.

Clin Cancer Res. 2001 Jan;7(1):127-35.

19.

Aberrant promoter methylation of multiple genes in non-small cell lung cancers.

Zöchbauer-Müller S, Fong KM, Virmani AK, Geradts J, Gazdar AF, Minna JD.

Cancer Res. 2001 Jan 1;61(1):249-55.

20.
21.

Chromosome 19 translocation, overexpression of Notch3, and human lung cancer.

Dang TP, Gazdar AF, Virmani AK, Sepetavec T, Hande KR, Minna JD, Roberts JR, Carbone DP.

J Natl Cancer Inst. 2000 Aug 16;92(16):1355-7. No abstract available.

PMID:
10944559
22.

Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.

Virmani AK, Rathi A, Zöchbauer-Müller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF.

J Natl Cancer Inst. 2000 Aug 16;92(16):1303-7.

PMID:
10944551
23.

Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines.

Larramendy ML, Lushnikova T, Björkqvist AM, Wistuba II, Virmani AK, Shivapurkar N, Gazdar AF, Knuutila S.

Cancer Genet Cytogenet. 2000 Jun;119(2):132-8.

PMID:
10867149
24.

High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.

Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, Girard L, Fondon JW 3rd, Garner HR, McKay B, Latif F, Lerman MI, Lam S, Gazdar AF, Minna JD.

Cancer Res. 2000 Apr 1;60(7):1949-60.

25.

Evidence of mucin secretion in human lung adenocarcinoma cell lines NCIH650 and NCIH2077 and effect of select secretagogues on mucin secretion.

Sharma PM, Sarkar MG, Virmani AK, Gazdar AF, Sachdev GP.

Biosci Rep. 1999 Oct;19(5):473-83.

PMID:
10763814
26.

Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer.

Park IW, Wistuba II, Maitra A, Milchgrub S, Virmani AK, Minna JD, Gazdar AF.

J Natl Cancer Inst. 1999 Nov 3;91(21):1863-8.

PMID:
10547393
27.

Multiple regions of chromosome 4 demonstrating allelic losses in breast carcinomas.

Shivapurkar N, Sood S, Wistuba II, Virmani AK, Maitra A, Milchgrub S, Minna JD, Gazdar AF.

Cancer Res. 1999 Aug 1;59(15):3576-80.

28.

Comparison of features of human lung cancer cell lines and their corresponding tumors.

Wistuba II, Bryant D, Behrens C, Milchgrub S, Virmani AK, Ashfaq R, Minna JD, Gazdar AF.

Clin Cancer Res. 1999 May;5(5):991-1000.

29.

Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer.

Wistuba II, Behrens C, Virmani AK, Milchgrub S, Syed S, Lam S, Mackay B, Minna JD, Gazdar AF.

Cancer Res. 1999 Apr 15;59(8):1973-9.

30.

Enrichment of epithelial cells for molecular studies.

Maitra A, Wistuba II, Virmani AK, Sakaguchi M, Park I, Stucky A, Milchgrub S, Gibbons D, Minna JD, Gazdar AF.

Nat Med. 1999 Apr;5(4):459-63. No abstract available.

PMID:
10202940
31.

Genetic changes in the spectrum of neuroendocrine lung tumors.

Onuki N, Wistuba II, Travis WD, Virmani AK, Yashima K, Brambilla E, Hasleton P, Gazdar AF.

Cancer. 1999 Feb 1;85(3):600-7.

PMID:
10091733
32.

Development of a sensitive, specific reverse transcriptase polymerase chain reaction-based assay for epithelial tumour cells in effusions.

Sakaguchi M, Virmani AK, Ashfaq R, Rogers TE, Rathi A, Liu Y, Kodagoda D, Cunningham HT, Gazdar AF.

Br J Cancer. 1999 Feb;79(3-4):416-22.

33.

Deletions of chromosome 4 at multiple sites are frequent in malignant mesothelioma and small cell lung carcinoma.

Shivapurkar N, Virmani AK, Wistuba II, Milchgrub S, Mackay B, Minna JD, Gazdar AF.

Clin Cancer Res. 1999 Jan;5(1):17-23.

34.

Comparison of features of human breast cancer cell lines and their corresponding tumors.

Wistuba II, Behrens C, Milchgrub S, Syed S, Ahmadian M, Virmani AK, Kurvari V, Cunningham TH, Ashfaq R, Minna JD, Gazdar AF.

Clin Cancer Res. 1998 Dec;4(12):2931-8.

35.

Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.

Tomlinson GE, Chen TT, Stastny VA, Virmani AK, Spillman MA, Tonk V, Blum JL, Schneider NR, Wistuba II, Shay JW, Minna JD, Gazdar AF.

Cancer Res. 1998 Aug 1;58(15):3237-42.

36.

Comparison between fluorescence in situ hybridization and classical cytogenetics in human tumors.

Virmani AK, Tonk VS, Gazdar AF.

Anticancer Res. 1998 May-Jun;18(3A):1351-6.

PMID:
9673339
37.

DNA analysis at p53 locus in adenoid cystic carcinoma: comparison of molecular study and p53 immunostaining.

Yamamoto Y, Wistuba II, Kishimoto Y, Virmani AK, Vuitch F, Albores-Saavedra J, Gazdar AF.

Pathol Int. 1998 Apr;48(4):273-80.

PMID:
9648155
38.

DNA analysis at p53 locus in carcinomas arising from pleomorphic adenomas of salivary glands: comparison of molecular study and p53 immunostaining.

Yamamoto Y, Kishimoto Y, Wistuba II, Virmani AK, Vuitch F, Gazdar AF, Albores-Saavedra J.

Pathol Int. 1998 Apr;48(4):265-72.

PMID:
9648154
39.

Comparison of molecular changes in lung cancers in HIV-positive and HIV-indeterminate subjects.

Wistuba II, Behrens C, Milchgrub S, Virmani AK, Jagirdar J, Thomas B, Ioachim HL, Litzky LA, Brambilla EM, Minna JD, Gazdar AF.

JAMA. 1998 May 20;279(19):1554-9.

PMID:
9605900
40.

Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types.

Virmani AK, Fong KM, Kodagoda D, McIntire D, Hung J, Tonk V, Minna JD, Gazdar AF.

Genes Chromosomes Cancer. 1998 Apr;21(4):308-19.

PMID:
9559342
41.

Molecular damage in the bronchial epithelium of current and former smokers.

Wistuba II, Lam S, Behrens C, Virmani AK, Fong KM, LeRiche J, Samet JM, Srivastava S, Minna JD, Gazdar AF.

J Natl Cancer Inst. 1997 Sep 17;89(18):1366-73.

42.

Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma.

Wistuba II, Montellano FD, Milchgrub S, Virmani AK, Behrens C, Chen H, Ahmadian M, Nowak JA, Muller C, Minna JD, Gazdar AF.

Cancer Res. 1997 Aug 1;57(15):3154-8.

43.

K-ras mutations and allelic loss at 5q and 18q in the development of human pancreatic cancers.

Sugio K, Molberg K, Albores-Saavedra J, Virmani AK, Kishimoto Y, Gazdar AF.

Int J Pancreatol. 1997 Jun;21(3):205-17.

PMID:
9322119
44.

Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes.

Yashima K, Piatyszek MA, Saboorian HM, Virmani AK, Brown D, Shay JW, Gazdar AF.

J Clin Pathol. 1997 Feb;50(2):110-7.

45.

Loss of heterozygosity and microsatellite alterations in p53 and RB genes in adenoid cystic carcinoma of the salivary glands.

Yamamoto Y, Virmani AK, Wistuba II, McIntire D, Vuitch F, Albores-Saavedra J, Gazdar AF.

Hum Pathol. 1996 Nov;27(11):1204-10.

PMID:
8912832
46.

Mutations associated with carcinomas arising from pleomorphic adenomas of the salivary glands.

Yamamoto Y, Kishimoto Y, Virmani AK, Smith A, Vuitch F, Albores-Saavedra J, Gazdar AF.

Hum Pathol. 1996 Aug;27(8):782-6.

PMID:
8760010
47.

Steroid-hormone receptors in cell lines and tumor biopsies of human lung cancer.

Kaiser U, Hofmann J, Schilli M, Wegmann B, Klotz U, Wedel S, Virmani AK, Wollmer E, Branscheid D, Gazdar AF, Havemann K.

Int J Cancer. 1996 Jul 29;67(3):357-64.

48.

Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers.

Kishimoto Y, Sugio K, Hung JY, Virmani AK, McIntire DD, Minna JD, Gazdar AF.

J Natl Cancer Inst. 1995 Aug 16;87(16):1224-9.

PMID:
7563168
49.

Allele-specific mutations involved in the pathogenesis of endemic gallbladder carcinoma in Chile.

Wistuba II, Sugio K, Hung J, Kishimoto Y, Virmani AK, Roa I, Albores-Saavedra J, Gazdar AF.

Cancer Res. 1995 Jun 15;55(12):2511-5.

50.

Frequent loss of the short arm of chromosome 9 in resected non-small-cell lung cancers from Japanese patients and its association with squamous cell carcinoma.

Kishimoto Y, Sugio K, Mitsudomi T, Oyama T, Virmani AK, McIntire DD, Gazdar AF.

J Cancer Res Clin Oncol. 1995;121(5):291-6.

PMID:
7768967

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