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Items: 1 to 50 of 89

1.

Gain-of-function IKBKB mutation causes human combined immune deficiency.

Cardinez C, Miraghazadeh B, Tanita K, da Silva E, Hoshino A, Okada S, Chand R, Asano T, Tsumura M, Yoshida K, Ohnishi H, Kato Z, Yamazaki M, Okuno Y, Miyano S, Kojima S, Ogawa S, Andrews TD, Field MA, Burgio G, Morio T, Vinuesa CG, Kanegane H, Cook MC.

J Exp Med. 2018 Nov 5;215(11):2715-2724. doi: 10.1084/jem.20180639. Epub 2018 Oct 18.

PMID:
30337470
2.

Systemic lupus erythematosus: A new autoimmune disorder in Kabuki syndrome.

Arsov T, Sestan M, Cekada N, Frkovic M, Andrews D, He Y, Shen N, Vinuesa CG, Jelusic M.

Eur J Med Genet. 2018 Sep 11. pii: S1769-7212(18)30319-7. doi: 10.1016/j.ejmg.2018.09.005. [Epub ahead of print]

PMID:
30213761
3.

Synaptic Interactions in Germinal Centers.

Papa I, Vinuesa CG.

Front Immunol. 2018 Aug 13;9:1858. doi: 10.3389/fimmu.2018.01858. eCollection 2018. Review.

4.

STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles.

Alshekaili J, Chand R, Lee CE, Corley S, Kwong K, Papa I, Fulcher DA, Randall KL, Leiding JW, Ma CS, Wilkins MR, Uzel G, Goodnow CC, Vinuesa CG, Tangye SG, Cook MC.

Sci Rep. 2018 Feb 23;8(1):3529. doi: 10.1038/s41598-018-21389-8.

5.

Atypical chemokine receptor 4 shapes activated B cell fate.

Kara EE, Bastow CR, McKenzie DR, Gregor CE, Fenix KA, Babb R, Norton TS, Zotos D, Rodda LB, Hermes JR, Bourne K, Gilchrist DS, Nibbs RJ, Alsharifi M, Vinuesa CG, Tarlinton DM, Brink R, Hill GR, Cyster JG, Comerford I, McColl SR.

J Exp Med. 2018 Mar 5;215(3):801-813. doi: 10.1084/jem.20171067. Epub 2018 Jan 31.

6.

HIV Immunogens: Affinity Is Key.

Prabhu S, Cockburn IA, Vinuesa CG.

Immunity. 2018 Jan 16;48(1):11-13. doi: 10.1016/j.immuni.2018.01.002.

PMID:
29343432
7.

Unconventional Pro-inflammatory CD4+ T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi.

Gorosito Serrán M, Tosello Boari J, Fiocca Vernengo F, Beccaría CG, Ramello MC, Bermejo DA, Cook AG, Vinuesa CG, Montes CL, Acosta Rodriguez EV, Gruppi A.

Front Immunol. 2017 Nov 21;8:1548. doi: 10.3389/fimmu.2017.01548. eCollection 2017.

8.

Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation.

Nagalingam G, Vinuesa CG, Britton WJ, Saunders BM.

J Immunol. 2017 Sep 1;199(5):1796-1804. doi: 10.4049/jimmunol.1602069. Epub 2017 Jul 26.

9.

TFH-derived dopamine accelerates productive synapses in germinal centres.

Papa I, Saliba D, Ponzoni M, Bustamante S, Canete PF, Gonzalez-Figueroa P, McNamara HA, Valvo S, Grimbaldeston M, Sweet RA, Vohra H, Cockburn IA, Meyer-Hermann M, Dustin ML, Doglioni C, Vinuesa CG.

Nature. 2017 Jul 20;547(7663):318-323. doi: 10.1038/nature23013. Epub 2017 Jul 12.

10.

Plexin B2 and Semaphorin 4C Guide T Cell Recruitment and Function in the Germinal Center.

Yan H, Wu L, Shih C, Hou S, Shi J, Mao T, Chen W, Melvin B, Rigby RJ, Chen Y, Jiang H, Friedel RH, Vinuesa CG, Qi H.

Cell Rep. 2017 May 2;19(5):995-1007. doi: 10.1016/j.celrep.2017.04.022.

11.

Germinal Center Lymphocyte Ratios and Successful HIV Vaccines.

Gonzalez-Figueroa P, Roco JA, Vinuesa CG.

Trends Mol Med. 2017 Feb;23(2):95-97. doi: 10.1016/j.molmed.2016.12.009. Epub 2017 Jan 12.

PMID:
28089302
12.

IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.

Vijayan D, Mohd Redzwan N, Avery DT, Wirasinha RC, Brink R, Walters G, Adelstein S, Kobayashi M, Gray P, Elliott M, Wong M, King C, Vinuesa CG, Ghilardi N, Ma CS, Tangye SG, Batten M.

J Immunol. 2016 Oct 15;197(8):3008-3017. Epub 2016 Sep 12.

13.

T Follicular Helper Cells in Transplantation.

Walters GD, Vinuesa CG.

Transplantation. 2016 Aug;100(8):1650-5. doi: 10.1097/TP.0000000000001217. Review.

PMID:
27362303
14.

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

Tan J, McKenzie C, Vuillermin PJ, Goverse G, Vinuesa CG, Mebius RE, Macia L, Mackay CR.

Cell Rep. 2016 Jun 21;15(12):2809-24. doi: 10.1016/j.celrep.2016.05.047.

15.

ROQUIN signalling pathways in innate and adaptive immunity.

Athanasopoulos V, Ramiscal RR, Vinuesa CG.

Eur J Immunol. 2016 May;46(5):1082-90. doi: 10.1002/eji.201545956. Epub 2016 Apr 23. Review.

16.

Follicular Helper T Cells.

Vinuesa CG, Linterman MA, Yu D, MacLennan IC.

Annu Rev Immunol. 2016 May 20;34:335-68. doi: 10.1146/annurev-immunol-041015-055605. Epub 2016 Feb 22. Review.

PMID:
26907215
17.

Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.

Ramiscal RR, Parish IA, Lee-Young RS, Babon JJ, Blagih J, Pratama A, Martin J, Hawley N, Cappello JY, Nieto PF, Ellyard JI, Kershaw NJ, Sweet RA, Goodnow CC, Jones RG, Febbraio MA, Vinuesa CG, Athanasopoulos V.

Elife. 2015 Oct 23;4. pii: e08698. doi: 10.7554/eLife.08698.

18.

Posttranscriptional T cell gene regulation to limit Tfh cells and autoimmunity.

Jiang SH, Shen N, Vinuesa CG.

Curr Opin Immunol. 2015 Dec;37:21-7. doi: 10.1016/j.coi.2015.09.003. Epub 2015 Sep 30. Review.

PMID:
26432764
19.

Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms.

Mino T, Murakawa Y, Fukao A, Vandenbon A, Wessels HH, Ori D, Uehata T, Tartey S, Akira S, Suzuki Y, Vinuesa CG, Ohler U, Standley DM, Landthaler M, Fujiwara T, Takeuchi O.

Cell. 2015 May 21;161(5):1058-1073. doi: 10.1016/j.cell.2015.04.029.

20.

Detection of mouse natural killer T follicular helper (NKT(FH)) cells by flow cytometry.

Chang PP, Vinuesa CG.

Methods Mol Biol. 2015;1291:135-41. doi: 10.1007/978-1-4939-2498-1_11.

PMID:
25836307
21.

Reducing the search space for causal genetic variants with VASP.

Field MA, Cho V, Cook MC, Enders A, Vinuesa CG, Whittle B, Andrews TD, Goodnow CC.

Bioinformatics. 2015 Jul 15;31(14):2377-9. doi: 10.1093/bioinformatics/btv135. Epub 2015 Mar 8.

22.

MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.

Pratama A, Srivastava M, Williams NJ, Papa I, Lee SK, Dinh XT, Hutloff A, Jordan MA, Zhao JL, Casellas R, Athanasopoulos V, Vinuesa CG.

Nat Commun. 2015 Mar 6;6:6436. doi: 10.1038/ncomms7436.

23.

Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.

Srivastava M, Duan G, Kershaw NJ, Athanasopoulos V, Yeo JH, Ose T, Hu D, Brown SH, Jergic S, Patel HR, Pratama A, Richards S, Verma A, Jones EY, Heissmeyer V, Preiss T, Dixon NE, Chong MM, Babon JJ, Vinuesa CG.

Nat Commun. 2015 Feb 20;6:6253. doi: 10.1038/ncomms7253.

24.

Pathophysiology of T follicular helper cells in humans and mice.

Ueno H, Banchereau J, Vinuesa CG.

Nat Immunol. 2015 Feb;16(2):142-52. doi: 10.1038/ni.3054. Review.

25.

Identification of a pathogenic variant in TREX1 in early-onset cerebral systemic lupus erythematosus by Whole-exome sequencing.

Ellyard JI, Jerjen R, Martin JL, Lee AY, Field MA, Jiang SH, Cappello J, Naumann SK, Andrews TD, Scott HS, Casarotto MG, Goodnow CC, Chaitow J, Pascual V, Hertzog P, Alexander SI, Cook MC, Vinuesa CG.

Arthritis Rheumatol. 2014 Dec;66(12):3382-6.

26.

Inflammation: gone with translation.

Vinuesa CG, Preiss T.

PLoS Genet. 2014 Jun 19;10(6):e1004442. doi: 10.1371/journal.pgen.1004442. eCollection 2014 Jun. No abstract available.

27.

Control of TFH cell numbers: why and how?

Pratama A, Vinuesa CG.

Immunol Cell Biol. 2014 Jan;92(1):40-8. doi: 10.1038/icb.2013.69. Epub 2013 Nov 5. Review.

PMID:
24189162
28.

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, Ghali JR, Cook MC, Riminton DS, Veillette A, Schwartzberg PL, Mackay F, Brink R, Tangye SG, Vinuesa CG, Mackay CR, Li Z, Yu D.

Immunity. 2013 Oct 17;39(4):770-81. doi: 10.1016/j.immuni.2013.09.007.

29.

New territory for T follicular helper cells.

Vinuesa CG, Fagarasan S, Dong C.

Immunity. 2013 Sep 19;39(3):417-20. doi: 10.1016/j.immuni.2013.09.001.

30.

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.

Lee JC, Espéli M, Anderson CA, Linterman MA, Pocock JM, Williams NJ, Roberts R, Viatte S, Fu B, Peshu N, Hien TT, Phu NH, Wesley E, Edwards C, Ahmad T, Mansfield JC, Gearry R, Dunstan S, Williams TN, Barton A, Vinuesa CG; UK IBD Genetics Consortium, Parkes M, Lyons PA, Smith KG.

Cell. 2013 Sep 26;155(1):57-69. doi: 10.1016/j.cell.2013.08.034. Epub 2013 Sep 12.

31.

Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.

Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, Fitch J, Botelho NK, Chang PP, Hu X, Hogan JJ, Maña P, Bernal D, Korner H, Yu D, Goodnow CC, Cook MC, Vinuesa CG.

Immunity. 2013 Apr 18;38(4):669-80. doi: 10.1016/j.immuni.2013.01.011. Epub 2013 Apr 11.

32.

Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation.

Teh CE, Horikawa K, Arnold CN, Beutler B, Kucharska EM, Vinuesa CG, Bertram EM, Goodnow CC, Enders A.

Genes Immun. 2013 Jun;14(4):223-33. doi: 10.1038/gene.2013.11. Epub 2013 Apr 4.

33.

T-cell subsets in the germinal center.

Ramiscal RR, Vinuesa CG.

Immunol Rev. 2013 Mar;252(1):146-55. doi: 10.1111/imr.12031. Review.

PMID:
23405902
34.

Innate B cell helpers reveal novel types of antibody responses.

Vinuesa CG, Chang PP.

Nat Immunol. 2013 Feb;14(2):119-26. doi: 10.1038/ni.2511. Epub 2013 Jan 18. Review.

PMID:
23334833
35.

Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers.

Lee SK, Silva DG, Martin JL, Pratama A, Hu X, Chang PP, Walters G, Vinuesa CG.

Immunity. 2012 Nov 16;37(5):880-92. doi: 10.1016/j.immuni.2012.10.010.

36.

Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity.

Sweet RA, Lee SK, Vinuesa CG.

Curr Opin Immunol. 2012 Dec;24(6):658-64. doi: 10.1016/j.coi.2012.10.003. Epub 2012 Nov 1. Review.

PMID:
23123277
37.

HIV and T follicular helper cells: a dangerous relationship.

Vinuesa CG.

J Clin Invest. 2012 Sep;122(9):3059-62. doi: 10.1172/JCI65175. Epub 2012 Aug 27.

38.

Heterozygosity for Roquinsan leads to angioimmunoblastic T-cell lymphoma-like tumors in mice.

Ellyard JI, Chia T, Rodriguez-Pinilla SM, Martin JL, Hu X, Navarro-Gonzalez M, Garcia JF, Delfau-Larue MH, Montes-Moreno S, Gaulard P, Cook MC, Walters G, Piris MA, Vinuesa CG.

Blood. 2012 Jul 26;120(4):812-21. doi: 10.1182/blood-2011-07-365130. Epub 2012 Jun 13.

39.

Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.

Chang PP, Lee SK, Hu X, Davey G, Duan G, Cho JH, Karupiah G, Sprent J, Heath WR, Bertram EM, Vinuesa CG.

J Immunol. 2012 Jul 15;189(2):701-10. doi: 10.4049/jimmunol.1102432. Epub 2012 Jun 8.

40.

T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells.

Linterman MA, Liston A, Vinuesa CG.

Immunol Rev. 2012 May;247(1):143-59. doi: 10.1111/j.1600-065X.2012.01121.x. Review.

PMID:
22500838
41.

Dysregulation of immune homeostasis in autoimmune diseases.

Kuchroo VK, Ohashi PS, Sartor RB, Vinuesa CG.

Nat Med. 2012 Jan 6;18(1):42-7. doi: 10.1038/nm.2621. No abstract available.

PMID:
22227671
42.

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses.

Chang PP, Barral P, Fitch J, Pratama A, Ma CS, Kallies A, Hogan JJ, Cerundolo V, Tangye SG, Bittman R, Nutt SL, Brink R, Godfrey DI, Batista FD, Vinuesa CG.

Nat Immunol. 2011 Nov 27;13(1):35-43. doi: 10.1038/ni.2166.

PMID:
22120117
43.

How T cells earn the follicular rite of passage.

Vinuesa CG, Cyster JG.

Immunity. 2011 Nov 23;35(5):671-80. doi: 10.1016/j.immuni.2011.11.001. Review.

44.

Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells.

Silva DG, Daley SR, Hogan J, Lee SK, Teh CE, Hu DY, Lam KP, Goodnow CC, Vinuesa CG.

Diabetes. 2011 Aug;60(8):2102-11. doi: 10.2337/db10-1344.

45.

Foxp3+ follicular regulatory T cells control the germinal center response.

Linterman MA, Pierson W, Lee SK, Kallies A, Kawamoto S, Rayner TF, Srivastava M, Divekar DP, Beaton L, Hogan JJ, Fagarasan S, Liston A, Smith KG, Vinuesa CG.

Nat Med. 2011 Jul 24;17(8):975-82. doi: 10.1038/nm.2425.

46.

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells.

Lee SK, Rigby RJ, Zotos D, Tsai LM, Kawamoto S, Marshall JL, Ramiscal RR, Chan TD, Gatto D, Brink R, Yu D, Fagarasan S, Tarlinton DM, Cunningham AF, Vinuesa CG.

J Exp Med. 2011 Jul 4;208(7):1377-88. doi: 10.1084/jem.20102065. Epub 2011 Jun 27.

47.

A BATF-ling connection between B cells and follicular helper T cells.

Ellyard JI, Vinuesa CG.

Nat Immunol. 2011 Jun;12(6):519-20. doi: 10.1038/ni.2042.

PMID:
21587310
48.

Blood relatives of follicular helper T cells.

Vinuesa CG, Cook MC.

Immunity. 2011 Jan 28;34(1):10-2. doi: 10.1016/j.immuni.2011.01.006.

49.

The elusive identity of T follicular helper cells.

Yu D, Vinuesa CG.

Trends Immunol. 2010 Oct;31(10):377-83. doi: 10.1016/j.it.2010.07.001. Epub 2010 Aug 31. Review.

PMID:
20810318
50.

T follicular helper cells during immunity and tolerance.

Linterman MA, Vinuesa CG.

Prog Mol Biol Transl Sci. 2010;92:207-48. doi: 10.1016/S1877-1173(10)92009-7. Review.

PMID:
20800823

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