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Items: 30


A phenome-wide Mendelian randomization study of pancreatic cancer using summary genetic data.

Langdon RJ, Richmond RC, Hemani G, Zheng J, Wade KH, Carreras-Torres R, Johannson M, Brennan P, Wootton RE, Munafo MR, Davey Smith G, Relton CL, Vincent EE, Martin RM, Haycock P.

Cancer Epidemiol Biomarkers Prev. 2019 Jul 17. pii: cebp.0036.2019. doi: 10.1158/1055-9965.EPI-19-0036. [Epub ahead of print]


Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation.

Jones N, Vincent EE, Cronin JG, Panetti S, Chambers M, Holm SR, Owens SE, Francis NJ, Finlay DK, Thornton CA.

Nat Commun. 2019 May 3;10(1):2042. doi: 10.1038/s41467-019-10023-4.


Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial.

Beynon RA, Richmond RC, Santos Ferreira DL, Ness AR, May M, Smith GD, Vincent EE, Adams C, Ala-Korpela M, Würtz P, Soidinsalo S, Metcalfe C, Donovan JL, Lane AJ, Martin RM; ProtecT Study Group; PRACTICAL consortium.

Int J Cancer. 2019 Apr 15;144(8):1918-1928. doi: 10.1002/ijc.31929. Epub 2018 Dec 7.


Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study.

Bell JA, Carslake D, Wade KH, Richmond RC, Langdon RJ, Vincent EE, Holmes MV, Timpson NJ, Davey Smith G.

PLoS Med. 2018 Aug 28;15(8):e1002641. doi: 10.1371/journal.pmed.1002641. eCollection 2018 Aug.


MELODI: Mining Enriched Literature Objects to Derive Intermediates.

Elsworth B, Dawe K, Vincent EE, Langdon R, Lynch BM, Martin RM, Relton C, Higgins JPT, Gaunt TR.

Int J Epidemiol. 2018 Jan 12. doi: 10.1093/ije/dyx251. [Epub ahead of print]


Experiences of patients undergoing pulmonary rehabilitation during an exacerbation of chronic respiratory disease.

Vincent EE, Chaplin EJ, Williams JE, Harvey-Dunstan T, Greening NJ, Steiner MC, Morgan MD, Singh SJ.

Chron Respir Dis. 2017 Aug;14(3):298-308. doi: 10.1177/1479972317695812. Epub 2017 Mar 9.


The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.

Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot MÉ, Mallette FA.

Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700.


The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism.

Izreig S, Samborska B, Johnson RM, Sergushichev A, Ma EH, Lussier C, Loginicheva E, Donayo AO, Poffenberger MC, Sagan SM, Vincent EE, Artyomov MN, Duchaine TF, Jones RG.

Cell Rep. 2016 Aug 16;16(7):1915-28. doi: 10.1016/j.celrep.2016.07.036. Epub 2016 Aug 4.


Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.

Lampropoulou V, Sergushichev A, Bambouskova M, Nair S, Vincent EE, Loginicheva E, Cervantes-Barragan L, Ma X, Huang SC, Griss T, Weinheimer CJ, Khader S, Randolph GJ, Pearce EJ, Jones RG, Diwan A, Diamond MS, Artyomov MN.

Cell Metab. 2016 Jul 12;24(1):158-66. doi: 10.1016/j.cmet.2016.06.004. Epub 2016 Jun 30.


GAM: a web-service for integrated transcriptional and metabolic network analysis.

Sergushichev AA, Loboda AA, Jha AK, Vincent EE, Driggers EM, Jones RG, Pearce EJ, Artyomov MN.

Nucleic Acids Res. 2016 Jul 8;44(W1):W194-200. doi: 10.1093/nar/gkw266. Epub 2016 Apr 20.


Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis.

Griss T, Vincent EE, Egnatchik R, Chen J, Ma EH, Faubert B, Viollet B, DeBerardinis RJ, Jones RG.

PLoS Biol. 2015 Dec 1;13(12):e1002309. doi: 10.1371/journal.pbio.1002309. eCollection 2015 Dec.


Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.

Vincent EE, Sergushichev A, Griss T, Gingras MC, Samborska B, Ntimbane T, Coelho PP, Blagih J, Raissi TC, Choinière L, Bridon G, Loginicheva E, Flynn BR, Thomas EC, Tavaré JM, Avizonis D, Pause A, Elder DJ, Artyomov MN, Jones RG.

Mol Cell. 2015 Oct 15;60(2):195-207. doi: 10.1016/j.molcel.2015.08.013.


PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer.

Dupuy F, Tabariès S, Andrzejewski S, Dong Z, Blagih J, Annis MG, Omeroglu A, Gao D, Leung S, Amir E, Clemons M, Aguilar-Mahecha A, Basik M, Vincent EE, St-Pierre J, Jones RG, Siegel PM.

Cell Metab. 2015 Oct 6;22(4):577-89. doi: 10.1016/j.cmet.2015.08.007. Epub 2015 Sep 10.


Bedside assessment of quadriceps muscle by ultrasound after admission for acute exacerbations of chronic respiratory disease.

Greening NJ, Harvey-Dunstan TC, Chaplin EJ, Vincent EE, Morgan MD, Singh SJ, Steiner MC.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):810-6. doi: 10.1164/rccm.201503-0535OC.


Specific Needs of Patients Attending Pulmonary Rehabilitation with an Interstitial Lung Disease Associated with Rheumatological Disease.

Vincent EE, Woodhead FA.

Respiration. 2015;90(1):87. doi: 10.1159/000431181. Epub 2015 Jun 3. No abstract available.


Meaningful patient education: How can pulmonary rehabilitation help to bridge the gap for those with interstitial lung disease?

Vincent EE.

Chron Respir Dis. 2015 May;12(2):83-4. doi: 10.1177/1479972315579363. No abstract available.


Bariatric surgery in morbidly obese insulin resistant humans normalises insulin signalling but not insulin-stimulated glucose disposal.

Chen MZ, Hudson CA, Vincent EE, de Berker DA, May MT, Hers I, Dayan CM, Andrews RC, Tavaré JM.

PLoS One. 2015 Apr 13;10(4):e0120084. doi: 10.1371/journal.pone.0120084. eCollection 2015.


The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.

Blagih J, Coulombe F, Vincent EE, Dupuy F, Galicia-Vázquez G, Yurchenko E, Raissi TC, van der Windt GJ, Viollet B, Pearce EL, Pelletier J, Piccirillo CA, Krawczyk CM, Divangahi M, Jones RG.

Immunity. 2015 Jan 20;42(1):41-54. doi: 10.1016/j.immuni.2014.12.030. Epub 2015 Jan 2.


Glycogen synthase kinase 3 protein kinase activity is frequently elevated in human non-small cell lung carcinoma and supports tumour cell proliferation.

Vincent EE, Elder DJ, O'Flaherty L, Pardo OE, Dzien P, Phillips L, Morgan C, Pawade J, May MT, Sohail M, Hetzel MR, Seckl MJ, Tavaré JM.

PLoS One. 2014 Dec 8;9(12):e114725. doi: 10.1371/journal.pone.0114725. eCollection 2014.


Differential effects of AMPK agonists on cell growth and metabolism.

Vincent EE, Coelho PP, Blagih J, Griss T, Viollet B, Jones RG.

Oncogene. 2015 Jul;34(28):3627-39. doi: 10.1038/onc.2014.301. Epub 2014 Sep 22.


An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: randomised controlled trial.

Greening NJ, Williams JE, Hussain SF, Harvey-Dunstan TC, Bankart MJ, Chaplin EJ, Vincent EE, Chimera R, Morgan MD, Singh SJ, Steiner MC.

BMJ. 2014 Jul 8;349:g4315. doi: 10.1136/bmj.g4315.


Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α.

Faubert B, Vincent EE, Griss T, Samborska B, Izreig S, Svensson RU, Mamer OA, Avizonis D, Shackelford DB, Shaw RJ, Jones RG.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2554-9. doi: 10.1073/pnas.1312570111. Epub 2014 Feb 3.


The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator.

Faubert B, Vincent EE, Poffenberger MC, Jones RG.

Cancer Lett. 2015 Jan 28;356(2 Pt A):165-70. doi: 10.1016/j.canlet.2014.01.018. Epub 2014 Jan 28. Review.


Targeting non-small cell lung cancer cells by dual inhibition of the insulin receptor and the insulin-like growth factor-1 receptor.

Vincent EE, Elder DJ, Curwen J, Kilgour E, Hers I, Tavaré JM.

PLoS One. 2013 Jun 24;8(6):e66963. doi: 10.1371/journal.pone.0066963. Print 2013.


Akt signalling in health and disease.

Hers I, Vincent EE, Tavaré JM.

Cell Signal. 2011 Oct;23(10):1515-27. doi: 10.1016/j.cellsig.2011.05.004. Epub 2011 May 17. Review.


Overexpression of the TXNDC5 protein in non-small cell lung carcinoma.

Vincent EE, Elder DJ, Phillips L, Heesom KJ, Pawade J, Luckett M, Sohail M, May MT, Hetzel MR, Tavaré JM.

Anticancer Res. 2011 May;31(5):1577-82.


Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer.

Vincent EE, Elder DJ, Thomas EC, Phillips L, Morgan C, Pawade J, Sohail M, May MT, Hetzel MR, Tavaré JM.

Br J Cancer. 2011 May 24;104(11):1755-61. doi: 10.1038/bjc.2011.132. Epub 2011 Apr 19.


Randomized controlled trial of dietary creatine as an adjunct therapy to physical training in chronic obstructive pulmonary disease.

Deacon SJ, Vincent EE, Greenhaff PL, Fox J, Steiner MC, Singh SJ, Morgan MD.

Am J Respir Crit Care Med. 2008 Aug 1;178(3):233-9. doi: 10.1164/rccm.200710-1508OC. Epub 2008 Apr 17.


A new antibody, anti-Fy3, in the Duffy blood group system.

Albrey JA, Vincent EE, Hutchinson J, Marsh WL, Allen FH Jr, Gavin J, Sanger R.

Vox Sang. 1971 Jan;20(1):29-35. No abstract available.


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