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Items: 32

1.

A Role for Oncostatin M in the Impairment of Glucose Homeostasis in Obesity.

Piquer-Garcia I, Campderros L, Taxerås SD, Gavaldà-Navarro A, Pardo R, Vila M, Pellitero S, Martínez E, Tarascó J, Moreno P, Villarroya J, Cereijo R, González L, Reyes M, Rodriguez-Fernández S, Vives-Pi M, Lerin C, Elks CM, Stephens JM, Puig-Domingo M, Villarroya F, Villena JA, Sánchez-Infantes D.

J Clin Endocrinol Metab. 2020 Mar 1;105(3). pii: dgz090. doi: 10.1210/clinem/dgz090.

PMID:
31606738
2.

Contribution of Impaired Insulin Signaling to the Pathogenesis of Diabetic Cardiomyopathy.

Zamora M, Villena JA.

Int J Mol Sci. 2019 Jun 11;20(11). pii: E2833. doi: 10.3390/ijms20112833. Review.

3.

Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program.

Sánchez-de-Diego C, Artigas N, Pimenta-Lopes C, Valer JA, Torrejon B, Gama-Pérez P, Villena JA, Garcia-Roves PM, Rosa JL, Ventura F.

iScience. 2019 May 31;15:79-94. doi: 10.1016/j.isci.2019.04.015. Epub 2019 Apr 12.

4.

Adipocyte MTERF4 regulates non-shivering adaptive thermogenesis and sympathetic-dependent glucose homeostasis.

Castillo A, Vilà M, Pedriza I, Pardo R, Cámara Y, Martín E, Beiroa D, Torres-Torronteras J, Oteo M, Morcillo MA, Martí R, Simó R, Nogueiras R, Villena JA.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1298-1312. doi: 10.1016/j.bbadis.2019.01.025. Epub 2019 Jan 26.

PMID:
30690068
5.

Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue.

Pardo R, Vilà M, Cervela L, de Marco M, Gama-Pérez P, González-Franquesa A, Statuto L, Vilallonga R, Simó R, Garcia-Roves PM, Villena JA.

FASEB J. 2019 Feb;33(2):2343-2358. doi: 10.1096/fj.201800310R. Epub 2018 Oct 2.

PMID:
30277821
6.

Kidney Androgen-Regulated Protein (KAP) Transgenic Mice Are Protected Against High-Fat Diet Induced Metabolic Syndrome.

de Quixano BB, Villena JA, Aranda M, Brils G, Cuevas A, Hespel T, Lekuona H, Súarez C, Tornavaca O, Meseguer A.

Sci Rep. 2017 Nov 23;7(1):16102. doi: 10.1038/s41598-017-16487-y.

7.

EndoG Knockout Mice Show Increased Brown Adipocyte Recruitment in White Adipose Tissue and Improved Glucose Homeostasis.

Pardo R, Blasco N, Vilà M, Beiroa D, Nogueiras R, Cañas X, Simó R, Sanchis D, Villena JA.

Endocrinology. 2016 Oct;157(10):3873-3887. Epub 2016 Aug 22.

PMID:
27547848
8.

Gene expression profiling in hearts of diabetic mice uncovers a potential role of estrogen-related receptor γ in diabetic cardiomyopathy.

Lasheras J, Vilà M, Zamora M, Riu E, Pardo R, Poncelas M, Cases I, Ruiz-Meana M, Hernández C, Feliu JE, Simó R, García-Dorado D, Villena JA.

Mol Cell Endocrinol. 2016 Jul 15;430:77-88. doi: 10.1016/j.mce.2016.04.004. Epub 2016 Apr 7.

PMID:
27062900
9.

HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance.

Arce-Cerezo A, García M, Rodríguez-Nuevo A, Crosa-Bonell M, Enguix N, Peró A, Muñoz S, Roca C, Ramos D, Franckhauser S, Elias I, Ferre T, Pujol A, Ruberte J, Villena JA, Bosch F, Riu E.

Sci Rep. 2015 Sep 28;5:14487. doi: 10.1038/srep14487.

10.

Pharmacological induction of mitochondrial biogenesis as a therapeutic strategy for the treatment of type 2 diabetes.

Zamora M, Pardo R, Villena JA.

Biochem Pharmacol. 2015 Nov 1;98(1):16-28. doi: 10.1016/j.bcp.2015.06.032. Epub 2015 Jul 23. Review.

PMID:
26212547
11.

New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond.

Villena JA.

FEBS J. 2015 Feb;282(4):647-72. doi: 10.1111/febs.13175. Epub 2015 Jan 12. Review.

12.

The db/db mouse: a useful model for the study of diabetic retinal neurodegeneration.

Bogdanov P, Corraliza L, Villena JA, Carvalho AR, Garcia-Arumí J, Ramos D, Ruberte J, Simó R, Hernández C.

PLoS One. 2014 May 16;9(5):e97302. doi: 10.1371/journal.pone.0097302. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e106227.

13.

Expression of adenine nucleotide translocase (ANT) isoform genes is controlled by PGC-1α through different transcription factors.

Gavaldà-Navarro A, Villena JA, Planavila A, Viñas O, Mampel T.

J Cell Physiol. 2014 Dec;229(12):2126-36. doi: 10.1002/jcp.24671.

PMID:
24819348
14.

Targeting mitochondrial biogenesis to treat insulin resistance.

Zamora M, Villena JA.

Curr Pharm Des. 2014;20(35):5527-57. Review.

PMID:
24606798
15.

Mice lacking PGC-1β in adipose tissues reveal a dissociation between mitochondrial dysfunction and insulin resistance.

Enguix N, Pardo R, González A, López VM, Simó R, Kralli A, Villena JA.

Mol Metab. 2013 Jun 5;2(3):215-26. doi: 10.1016/j.molmet.2013.05.004. eCollection 2013.

16.

Pref-1 in brown adipose tissue: specific involvement in brown adipocyte differentiation and regulatory role of C/EBPδ.

Armengol J, Villena JA, Hondares E, Carmona MC, Sul HS, Iglesias R, Giralt M, Villarroya F.

Biochem J. 2012 May 1;443(3):799-810. doi: 10.1042/BJ20111714.

PMID:
22324440
17.

Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1α.

Pardo R, Enguix N, Lasheras J, Feliu JE, Kralli A, Villena JA.

PLoS One. 2011;6(11):e26989. doi: 10.1371/journal.pone.0026989. Epub 2011 Nov 7.

18.

Peroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype.

Giralt A, Hondares E, Villena JA, Ribas F, Díaz-Delfín J, Giralt M, Iglesias R, Villarroya F.

J Biol Chem. 2011 May 13;286(19):16958-66. doi: 10.1074/jbc.M110.202390. Epub 2011 Mar 27.

19.

Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy.

Villena JA, Choi CS, Wang Y, Kim S, Hwang YJ, Kim YB, Cline G, Shulman GI, Sul HS.

Diabetes. 2008 Dec;57(12):3258-66. doi: 10.2337/db07-1739. Epub 2008 Oct 3.

20.

ERRalpha: a metabolic function for the oldest orphan.

Villena JA, Kralli A.

Trends Endocrinol Metab. 2008 Oct;19(8):269-76. doi: 10.1016/j.tem.2008.07.005. Epub 2008 Sep 6. Review.

21.

Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis.

Villena JA, Hock MB, Chang WY, Barcas JE, Giguère V, Kralli A.

Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1418-23. Epub 2007 Jan 17.

22.

Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.

Herzog B, Cardenas J, Hall RK, Villena JA, Budge PJ, Giguère V, Granner DK, Kralli A.

J Biol Chem. 2006 Jan 6;281(1):99-106. Epub 2005 Nov 2.

23.
24.

Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit.

Villena JA, Viollet B, Andreelli F, Kahn A, Vaulont S, Sul HS.

Diabetes. 2004 Sep;53(9):2242-9.

25.

Pref-1 and ADSF/resistin: two secreted factors inhibiting adipose tissue development.

Villena JA, Kim KH, Sul HS.

Horm Metab Res. 2002 Nov-Dec;34(11-12):664-70. Review.

PMID:
12660879
26.

Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1).

Lee K, Villena JA, Moon YS, Kim KH, Lee S, Kang C, Sul HS.

J Clin Invest. 2003 Feb;111(4):453-61.

27.

Mitochondrial biogenesis in brown adipose tissue is associated with differential expression of transcription regulatory factors.

Villena JA, Carmona MC, Rodriguez de la Concepción M, Rossmeisl M, Viñas O, Mampel T, Iglesias R, Giralt M, Villarroya F.

Cell Mol Life Sci. 2002 Nov;59(11):1934-44.

PMID:
12530524
28.

Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity.

Moon YS, Smas CM, Lee K, Villena JA, Kim KH, Yun EJ, Sul HS.

Mol Cell Biol. 2002 Aug;22(15):5585-92.

29.

Adipose tissues display differential phagocytic and microbicidal activities depending on their localization.

Villena JA, Cousin B, Pénicaud L, Casteilla L.

Int J Obes Relat Metab Disord. 2001 Sep;25(9):1275-80.

PMID:
11571587
31.

Influence of thyroid hormones on the human ATP synthase beta-subunit gene promoter.

Martin I, Villena JA, Giralt M, Iglesias R, Mampel T, Vińas O, Villarroya F.

Mol Cell Biochem. 1996 Jan 26;154(2):107-11.

PMID:
8717424
32.

ETS transcription factors regulate the expression of the gene for the human mitochondrial ATP synthase beta-subunit.

Villena JA, Martin I, Viñas O, Cormand B, Iglesias R, Mampel T, Giralt M, Villarroya F.

J Biol Chem. 1994 Dec 23;269(51):32649-54.

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