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Items: 20


Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses.

Shaw TN, Inkson CA, Villegas-Mendez A, Pattinson DJ, Strangward P, Else KJ, Draper SJ, Zeef LAH, Couper KN.

Front Immunol. 2019 Feb 19;10:248. doi: 10.3389/fimmu.2019.00248. eCollection 2019.


Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments.

Villegas-Mendez A, Strangward P, Shaw TN, Rajkovic I, Tosevski V, Forman R, Muller W, Couper KN.

Infect Immun. 2017 Oct 18;85(11). pii: e01035-16. doi: 10.1128/IAI.01035-16. Print 2017 Nov.


Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.

Shaw TN, Stewart-Hutchinson PJ, Strangward P, Dandamudi DB, Coles JA, Villegas-Mendez A, Gallego-Delgado J, van Rooijen N, Zindy E, Rodriguez A, Brewer JM, Couper KN, Dustin ML.

PLoS Pathog. 2015 Nov 12;11(11):e1005210. doi: 10.1371/journal.ppat.1005210. eCollection 2015.


Parasite-Specific CD4+ IFN-γ+ IL-10+ T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection.

Villegas-Mendez A, Shaw TN, Inkson CA, Strangward P, de Souza JB, Couper KN.

Infect Immun. 2015 Oct 12;84(1):34-46. doi: 10.1128/IAI.01100-15. Print 2016 Jan.


WSX-1 signalling inhibits CD4⁺ T cell migration to the liver during malaria infection by repressing chemokine-independent pathways.

Villegas-Mendez A, Gwyer Findlay E, de Souza JB, Grady LM, Saris CJ, Lane TE, Riley EM, Couper KN.

PLoS One. 2013 Nov 7;8(11):e78486. doi: 10.1371/journal.pone.0078486. eCollection 2013.


IL-27 receptor signaling regulates memory CD4+ T cell populations and suppresses rapid inflammatory responses during secondary malaria infection.

Gwyer Findlay E, Villegas-Mendez A, O'Regan N, de Souza JB, Grady LM, Saris CJ, Riley EM, Couper KN.

Infect Immun. 2014 Jan;82(1):10-20. doi: 10.1128/IAI.01091-13. Epub 2013 Oct 7.


IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.

Villegas-Mendez A, de Souza JB, Lavelle SW, Gwyer Findlay E, Shaw TN, van Rooijen N, Saris CJ, Hunter CA, Riley EM, Couper KN.

PLoS Pathog. 2013;9(4):e1003293. doi: 10.1371/journal.ppat.1003293. Epub 2013 Apr 11.


IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.

Gwyer Findlay E, Villegas-Mendez A, de Souza JB, Inkson CA, Shaw TN, Saris CJ, Hunter CA, Riley EM, Couper KN.

J Immunol. 2013 May 1;190(9):4553-61. doi: 10.4049/jimmunol.1202916. Epub 2013 Mar 27.


Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron.

Villegas-Méndez A, Fender P, Garin MI, Rothe R, Liguori L, Marques B, Lenormand JL.

PLoS One. 2012;7(9):e45416. doi: 10.1371/journal.pone.0045416. Epub 2012 Sep 27.


IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain.

Villegas-Mendez A, Greig R, Shaw TN, de Souza JB, Gwyer Findlay E, Stumhofer JS, Hafalla JC, Blount DG, Hunter CA, Riley EM, Couper KN.

J Immunol. 2012 Jul 15;189(2):968-79. doi: 10.4049/jimmunol.1200688. Epub 2012 Jun 20.


Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.

Villegas-Mendez A, de Souza JB, Murungi L, Hafalla JC, Shaw TN, Greig R, Riley EM, Couper KN.

J Immunol. 2011 Sep 15;187(6):2885-97. doi: 10.4049/jimmunol.1100241. Epub 2011 Aug 31.


Characterization of the cell-penetrating properties of the Epstein-Barr virus ZEBRA trans-activator.

Rothe R, Liguori L, Villegas-Mendez A, Marques B, Grunwald D, Drouet E, Lenormand JL.

J Biol Chem. 2010 Jun 25;285(26):20224-33. doi: 10.1074/jbc.M110.101550. Epub 2010 Apr 9.


In vivo delivery of antigens by adenovirus dodecahedron induces cellular and humoral immune responses to elicit antitumor immunity.

Villegas-Mendez A, Garin MI, Pineda-Molina E, Veratti E, Bueren JA, Fender P, Lenormand JL.

Mol Ther. 2010 May;18(5):1046-53. doi: 10.1038/mt.2010.16. Epub 2010 Feb 23.


Liposomes-mediated delivery of pro-apoptotic therapeutic membrane proteins.

Liguori L, Marques B, Villegas-Mendez A, Rothe R, Lenormand JL.

J Control Release. 2008 Mar 20;126(3):217-27. doi: 10.1016/j.jconrel.2007.12.004. Epub 2007 Dec 14.


Liposome-mediated cellular delivery of active gp91(phox).

Marques B, Liguori L, Paclet MH, Villegas-Mendéz A, Rothe R, Morel F, Lenormand JL.

PLoS One. 2007 Sep 12;2(9):e856.


Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3.

Villegas-Mendez A, Montes R, Ambrose LR, Warrens AN, Laffan M, Lane DA.

J Thromb Haemost. 2007 May;5(5):980-8.


Production of membrane proteins using cell-free expression systems.

Liguori L, Marques B, Villegas-Méndez A, Rothe R, Lenormand JL.

Expert Rev Proteomics. 2007 Feb;4(1):79-90. Review.


Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation.

Preston RJ, Villegas-Mendez A, Sun YH, Hermida J, Simioni P, Philippou H, Dahlbäck B, Lane DA.

FEBS J. 2005 Jan;272(1):97-108.


Identification and characterization of a natural R96C EPCR variant.

Hermida J, Hurtado V, Villegas-Mendez A, Catto AJ, Philippou H.

J Thromb Haemost. 2003 Aug;1(8):1850-2. No abstract available.

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