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Items: 1 to 50 of 119

1.

Immune-neuroendocrine and metabolic disorders in human and experimental T. cruzi infection: New clues for understanding Chagas disease pathology.

González FB, Villar SR, Pacini MF, Bottasso OA, Pérez AR.

Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165642. doi: 10.1016/j.bbadis.2019.165642. Epub 2019 Dec 19. Review.

PMID:
31866417
2.

AORTIC COMPLICATIONS IN MARFAN SYNDROME. SHOULD WE ANTICIPATE PREVENTIVE AORTIC ROOT SURGERY?

Martín C, Evangelista A, Serrano-Fiz S, Villar S, Ospina V, Martínez D, De Villarreal J, Sanchez V, Moñivas V, Mingo S, Forteza A.

Ann Thorac Surg. 2019 Oct 4. pii: S0003-4975(19)31488-2. doi: 10.1016/j.athoracsur.2019.08.096. [Epub ahead of print]

PMID:
31589859
3.

Long-term outcomes of aortic valve reimplantation in Marfan syndrome.

Martín CE, Villar S, Serrano-Fiz S, Moñivas V, González A, Forteza A.

Rev Esp Cardiol (Engl Ed). 2020 Jan;73(1):96-97. doi: 10.1016/j.rec.2019.06.011. Epub 2019 Sep 25. English, Spanish. No abstract available.

PMID:
31561983
4.

A multicenter study of anticoagulation in operable chronic thromboembolic pulmonary hypertension.

Bunclark K, Newnham M, Chiu YD, Ruggiero A, Villar SS, Cannon JE, Coghlan G, Corris PA, Howard L, Jenkins D, Johnson M, Kiely DG, Ng C, Screaton N, Sheares K, Taboada D, Tsui S, Wort SJ, Pepke-Zaba J, Toshner M.

J Thromb Haemost. 2020 Jan;18(1):114-122. doi: 10.1111/jth.14649. Epub 2019 Oct 18.

PMID:
31557382
5.

Acute kidney injury after thoracic surgery: a proposal for a multicentre evaluation (MERITS).

Naruka V, Mckie MA, Khushiwal R, Clayton J, Aresu G, Peryt A, Villar SS, MacKay J, Coonar AS.

Interact Cardiovasc Thorac Surg. 2019 Dec 1;29(6):861-866. doi: 10.1093/icvts/ivz184.

PMID:
31393555
6.

A response-adaptive randomization procedure for multi-armed clinical trials with normally distributed outcomes.

Williamson SF, Villar SS.

Biometrics. 2019 Jul 19. doi: 10.1111/biom.13119. [Epub ahead of print]

PMID:
31322732
7.

The role of Glucagon-Like Peptide 1 Loading on periprocedural myocardial infarction During elective PCI (GOLD-PCI study): A randomized, placebo-controlled trial.

Giblett JP, Clarke S, Zhao T, McCormick LM, Braganza DM, Densem CG, O'Sullivan M, Adlam D, Clarke SC, Steele J, Fielding S, West NEJ, Villar SS, Hoole SP.

Am Heart J. 2019 Sep;215:41-51. doi: 10.1016/j.ahj.2019.05.013. Epub 2019 Jun 9.

PMID:
31277053
8.

Measurement of extravascular lung water to diagnose severe reperfusion lung injury following pulmonary endarterectomy: a prospective cohort clinical validation study.

Butchart AG, Zochios V, Villar SS, Jones NL, Curry S, Agrawal B, Jenkins DP, Klein AA.

Anaesthesia. 2019 Oct;74(10):1282-1289. doi: 10.1111/anae.14744. Epub 2019 Jul 4.

9.

Logistic early warning scores to predict death, cardiac arrest or unplanned intensive care unit re-admission after cardiac surgery.

Chiu YD, Villar SS, Brand JW, Patteril MV, Morrice DJ, Clayton J, Mackay JH.

Anaesthesia. 2020 Feb;75(2):162-170. doi: 10.1111/anae.14755. Epub 2019 Jul 3.

PMID:
31270799
10.

Obstructive Sleep Apnea in Patients With Primary-open Angle Glaucoma: No Role for a Screening Program.

Wozniak D, Bourne R, Peretz G, Kean J, Willshire C, Harun S, Villar S, Chiu YD, Smith I.

J Glaucoma. 2019 Aug;28(8):668-675. doi: 10.1097/IJG.0000000000001296.

PMID:
31162178
11.

Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans.

Zhivagui M, Ng AWT, Ardin M, Churchwell MI, Pandey M, Renard C, Villar S, Cahais V, Robitaille A, Bouaoun L, Heguy A, Guyton KZ, Stampfer MR, McKay J, Hollstein M, Olivier M, Rozen SG, Beland FA, Korenjak M, Zavadil J.

Genome Res. 2019 Apr;29(4):521-531. doi: 10.1101/gr.242453.118. Epub 2019 Mar 7.

12.

β-adrenergic-mediated dynamic augmentation of sarcolemmal CaV 1.2 clustering and co-operativity in ventricular myocytes.

Ito DW, Hannigan KI, Ghosh D, Xu B, Del Villar SG, Xiang YK, Dickson EJ, Navedo MF, Dixon RE.

J Physiol. 2019 Apr;597(8):2139-2162. doi: 10.1113/JP277283. Epub 2019 Mar 12.

13.

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.

Newnham M, South K, Bleda M, Auger WR, Barberà JA, Bogaard H, Bunclark K, Cannon JE, Delcroix M, Hadinnapola C, Howard LS, Jenkins D, Mayer E, Ng C, Rhodes CJ, Screaton N, Sheares K, Simpson MA, Southwood M, Su L, Taboada D, Traylor M, Trembath RC, Villar SS, Wilkins MR, Wharton J, Gräf S, Pepke-Zaba J, Laffan M, Lane DA, Morrell NW, Toshner M.

Eur Respir J. 2019 Mar 28;53(3). pii: 1801805. doi: 10.1183/13993003.01805-2018. Print 2019 Mar.

14.

Molecular features of premenopausal breast cancers in Latin American women: Pilot results from the PRECAMA study.

Olivier M, Bouaoun L, Villar S, Robitaille A, Cahais V, Heguy A, Byrnes G, Le Calvez-Kelm F, Torres-Mejía G, Alvarado-Cabrero I, Imani-Razavi FS, Inés Sánchez G, Jaramillo R, Porras C, Rodriguez AC, Garmendia ML, Soto JL, Romieu I, Porter P, Guenthoer J, Rinaldi S; PRECAMA team.

PLoS One. 2019 Jan 17;14(1):e0210372. doi: 10.1371/journal.pone.0210372. eCollection 2019.

15.

Revisiting the difference between instrumental and terminal values to predict (stimulating) prosocial behaviours: The transcendental-change profile.

Oceja L, Stocks E, Heerdink M, Villar S, Salgado S, Carrera P, Arribas M, Bargsted M, Beramendi M, Caballero A, Espinosa A, Escanés G, Lima L, Muñoz D, Nájera P, Pereira S, Villegas M, Zubieta E.

Br J Soc Psychol. 2019 Jul;58(3):749-768. doi: 10.1111/bjso.12306. Epub 2018 Dec 12.

PMID:
30548477
16.

Immune response triggered by Trypanosoma cruzi infection strikes adipose tissue homeostasis altering lipid storage, enzyme profile and adipokine expression.

González FB, Villar SR, Toneatto J, Pacini MF, Márquez J, D'Attilio L, Bottasso OA, Piwien-Pilipuk G, Pérez AR.

Med Microbiol Immunol. 2019 Oct;208(5):651-666. doi: 10.1007/s00430-018-0572-z. Epub 2018 Nov 9.

PMID:
30413884
17.

Umbilical hernia repair with composite prosthesis: a single-centre experience.

Porrero JL, Cano-Valderrama O, Villar S, Sánchez-Cabezudo C, Ramos B, Porrero B, Cendrero M, Bonachia O, Torres AJ.

Hernia. 2019 Feb;23(1):143-147. doi: 10.1007/s10029-018-1843-8. Epub 2018 Nov 2.

PMID:
30390145
18.

Genetic Engineering of Lactococcus lactis Co-producing Antigen and the Mucosal Adjuvant 3' 5'- cyclic di Adenosine Monophosphate (c-di-AMP) as a Design Strategy to Develop a Mucosal Vaccine Prototype.

Quintana I, Espariz M, Villar SR, González FB, Pacini MF, Cabrera G, Bontempi I, Prochetto E, Stülke J, Perez AR, Marcipar I, Blancato V, Magni C.

Front Microbiol. 2018 Sep 4;9:2100. doi: 10.3389/fmicb.2018.02100. eCollection 2018.

19.

Dysregulated Network of Immune, Endocrine and Metabolic Markers is Associated to More Severe Human Chronic Chagas Cardiomyopathy.

González F, Villar S, D'Attilio L, Leiva R, Marquez J, Lioi S, Beloscar J, Bottasso O, Perez AR.

Neuroimmunomodulation. 2018;25(3):119-128. doi: 10.1159/000491699. Epub 2018 Sep 25.

20.

Cloning and Functional Characterisation of the Duplicated RDL Subunits from the Pea Aphid, Acyrthosiphon pisum.

Del Villar SG, Jones AK.

Int J Mol Sci. 2018 Jul 31;19(8). pii: E2235. doi: 10.3390/ijms19082235.

21.

Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet.

Lambertucci F, Arboatti A, Sedlmeier MG, Motiño O, Alvarez ML, Ceballos MP, Villar SR, Roggero E, Monti JA, Pisani G, Quiroga AD, Martín-Sanz P, Carnovale CE, Francés DE, Ronco MT.

J Nutr Biochem. 2018 Aug;58:17-27. doi: 10.1016/j.jnutbio.2018.04.013. Epub 2018 May 2.

PMID:
29860102
22.

Serological and molecular detection of Theileria equi and Babesia caballi in Philippine horses.

Ybañez AP, Ybañez RHD, Talle MG, Arreglo RMT, Geens MJC, Villas JGI 3rd, Villar SR, Laruga CL, Cao S, Moumouni FPA, Liu M, Igarashi I, Xuan X.

Ticks Tick Borne Dis. 2018 Jul;9(5):1125-1128. doi: 10.1016/j.ttbdis.2018.04.010. Epub 2018 Apr 18.

PMID:
29693550
23.

Anti-PD1 associated fulminant myocarditis after a single pembrolizumab dose: the role of occult pre-existing autoimmunity.

Martinez-Calle N, Rodriguez-Otero P, Villar S, Mejías L, Melero I, Prosper F, Marinello P, Paiva B, Idoate M, San-Miguel J.

Haematologica. 2018 Jul;103(7):e318-e321. doi: 10.3324/haematol.2017.185777. Epub 2018 Apr 12. No abstract available.

24.

Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints.

Smith AL, Villar SS.

J Appl Stat. 2018;45(6):1052-1076. doi: 10.1080/02664763.2017.1342780. Epub 2017 Jun 28.

25.

Bandit strategies evaluated in the context of clinical trials in rare life-threatening diseases.

Villar SS.

Probab Eng Inf Sci. 2018 Apr;32(2):229-245. doi: 10.1017/S0269964817000146. Epub 2017 Jun 7.

26.

Adaptive designs in clinical trials: why use them, and how to run and report them.

Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T.

BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7.

27.

Response-adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?

Villar SS, Bowden J, Wason J.

Pharm Stat. 2018 Mar;17(2):182-197. doi: 10.1002/pst.1845. Epub 2017 Dec 19.

28.

Papillary architecture of the lingual surface in the puma (Puma concolor).

Erdoğan S, Villar S, König HE, Pérez W.

Anat Histol Embryol. 2018 Feb;47(1):51-57. doi: 10.1111/ahe.12323. Epub 2017 Nov 19.

PMID:
29152772
29.

Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors.

Huang MN, Yu W, Teoh WW, Ardin M, Jusakul A, Ng AWT, Boot A, Abedi-Ardekani B, Villar S, Myint SS, Othman R, Poon SL, Heguy A, Olivier M, Hollstein M, Tan P, Teh BT, Sabapathy K, Zavadil J, Rozen SG.

Genome Res. 2017 Sep;27(9):1475-1486. doi: 10.1101/gr.220038.116. Epub 2017 Jul 24.

30.

Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing.

Huskova H, Ardin M, Weninger A, Vargova K, Barrin S, Villar S, Olivier M, Stopka T, Herceg Z, Hollstein M, Zavadil J, Korenjak M.

Oncogene. 2017 Oct 26;36(43):6041-6048. doi: 10.1038/onc.2017.215. Epub 2017 Jul 10.

31.

Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule.

Villar SS, Rosenberger WF.

Biometrics. 2018 Mar;74(1):49-57. doi: 10.1111/biom.12738. Epub 2017 Jul 6.

32.

Death of adrenocortical cells during murine acute T. cruzi infection is not associated with TNF-R1 signaling but mostly with the type II pathway of Fas-mediated apoptosis.

Pérez AR, Lambertucci F, González FB, Roggero EA, Bottasso OA, de Meis J, Ronco MT, Villar SR.

Brain Behav Immun. 2017 Oct;65:284-295. doi: 10.1016/j.bbi.2017.05.017. Epub 2017 Jun 27.

PMID:
28666938
33.

Performance of a Quantitative PCR-Based Assay and Beta-d-Glucan Detection for Diagnosis of Invasive Candidiasis in Very-Low-Birth-Weight Preterm Neonatal Patients (CANDINEO Study).

Ramos JT, Villar S, Bouza E, Bergon-Sendin E, Perez Rivilla A, Collados CT, Andreu M, Reyes CS, Campos-Herrero MI, de Heredia JL, Herrera MCL, Alonso PA, Pallás-Alonso CR, Cuenca-Estrella M; CANDINEO Study Group.

J Clin Microbiol. 2017 Sep;55(9):2752-2764. doi: 10.1128/JCM.00496-17. Epub 2017 Jun 28.

34.

A Bayesian adaptive design for clinical trials in rare diseases.

Williamson SF, Jacko P, Villar SS, Jaki T.

Comput Stat Data Anal. 2017 Sep;113:136-153. doi: 10.1016/j.csda.2016.09.006. Epub 2016 Sep 28.

35.

The fifth subunit of the (α4β2)2 β2 nicotinic ACh receptor modulates maximal ACh responses.

New K, Del Villar SG, Mazzaferro S, Alcaino C, Bermudez I.

Br J Pharmacol. 2018 Jun;175(11):1822-1837. doi: 10.1111/bph.13905. Epub 2017 Jul 14.

36.

Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.

Lambertucci F, Motiño O, Villar S, Rigalli JP, de Luján Alvarez M, Catania VA, Martín-Sanz P, Carnovale CE, Quiroga AD, Francés DE, Ronco MT.

Toxicol Appl Pharmacol. 2017 Jan 15;315:12-22. doi: 10.1016/j.taap.2016.11.015. Epub 2016 Nov 27.

PMID:
27899278
37.

The sympathetic nervous system affects the susceptibility and course of Trypanosoma cruzi infection.

Roggero E, Pérez AR, Pollachini N, Villar SR, Wildmann J, Besedovsky H, Del Rey A.

Brain Behav Immun. 2016 Nov;58:228-236. doi: 10.1016/j.bbi.2016.07.163. Epub 2016 Jul 30.

PMID:
27485039
38.

Evasion and Immuno-Endocrine Regulation in Parasite Infection: Two Sides of the Same Coin in Chagas Disease?

Morrot A, Villar SR, González FB, Pérez AR.

Front Microbiol. 2016 May 23;7:704. doi: 10.3389/fmicb.2016.00704. eCollection 2016. Review.

39.

INDEXABILITY AND OPTIMAL INDEX POLICIES FOR A CLASS OF REINITIALISING RESTLESS BANDITS.

Villar SS.

Probab Eng Inf Sci. 2016 Jan;30(1):1-23. Epub 2015 Oct 16.

40.

Trypanosoma cruzi Experimental Infection Impacts on the Thymic Regulatory T Cell Compartment.

González FB, Calmon-Hamaty F, Nô Seara Cordeiro S, Fernández Bussy R, Spinelli SV, D'Attilio L, Bottasso O, Savino W, Cotta-de-Almeida V, Villar SR, Pérez AR.

PLoS Negl Trop Dis. 2016 Jan 8;10(1):e0004285. doi: 10.1371/journal.pntd.0004285. eCollection 2016 Jan.

41.

Circulating free DNA concentration is an independent prognostic biomarker in lung cancer.

Tissot C, Toffart AC, Villar S, Souquet PJ, Merle P, Moro-Sibilot D, Pérol M, Zavadil J, Brambilla C, Olivier M, Couraud S.

Eur Respir J. 2015 Dec;46(6):1773-80. doi: 10.1183/13993003.00676-2015. Epub 2015 Oct 22.

42.

Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.

Castells X, Karanović S, Ardin M, Tomić K, Xylinas E, Durand G, Villar S, Forey N, Le Calvez-Kelm F, Voegele C, Karlović K, Mišić M, Dittrich D, Dolgalev I, McKay J, Shariat SF, Sidorenko VS, Fernandes A, Heguy A, Dickman KG, Olivier M, Grollman AP, Jelaković B, Zavadil J.

Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1873-81. doi: 10.1158/1055-9965.EPI-15-0553. Epub 2015 Sep 17.

43.

Umbilical Hernia Repair: Analysis After 934 Procedures.

Porrero JL, Cano-Valderrama O, Marcos A, Bonachia O, Ramos B, Alcaide B, Villar S, Sánchez-Cabezudo C, Quirós E, Alonso MT, Castillo MJ.

Am Surg. 2015 Sep;81(9):899-903.

PMID:
26350669
44.

[Free circulating DNA as a tool for lung cancer patients management].

Tissot C, Villar S, Olivier M, Couraud S.

Rev Pneumol Clin. 2016 Feb;72(1):61-71. doi: 10.1016/j.pneumo.2015.05.001. Epub 2015 Jul 17. Review. French.

PMID:
26190335
45.

Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule.

Villar SS, Wason J, Bowden J.

Biometrics. 2015 Dec;71(4):969-78. doi: 10.1111/biom.12337. Epub 2015 Jun 22.

46.

Revealing the Molecular Portrait of Triple Negative Breast Tumors in an Understudied Population through Omics Analysis of Formalin-Fixed and Paraffin-Embedded Tissues.

Vaca-Paniagua F, Alvarez-Gomez RM, Maldonado-Martínez HA, Pérez-Plasencia C, Fragoso-Ontiveros V, Lasa-Gonsebatt F, Herrera LA, Cantú D, Bargallo-Rocha E, Mohar A, Durand G, Forey N, Voegele C, Vallée M, Le Calvez-Kelm F, McKay J, Ardin M, Villar S, Zavadil J, Olivier M.

PLoS One. 2015 May 11;10(5):e0126762. doi: 10.1371/journal.pone.0126762. eCollection 2015.

47.

Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.

Traoré F, Gormally E, Villar S, Friesen MD, Groopman JD, Vernet G, Diallo S, Hainaut P, Maiga MY.

BMC Infect Dis. 2015 Apr 11;15:180. doi: 10.1186/s12879-015-0916-x.

48.

Role of Proteus mirabilis MR/P fimbriae and flagella in adhesion, cytotoxicity and genotoxicity induction in T24 and Vero cells.

Scavone P, Villar S, Umpiérrez A, Zunino P.

Pathog Dis. 2015 Jun;73(4). pii: ftv017. doi: 10.1093/femspd/ftv017. Epub 2015 Feb 26.

PMID:
25724892
49.

Prevalence and risk factors for biopsy-proven non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in a prospective cohort of adult patients with gallstones.

García-Monzón C, Vargas-Castrillón J, Porrero JL, Alonso MT, Bonachía O, Castillo MJ, Marcos A, Quirós E, Ramos B, Sánchez-Cabezudo C, Villar S, Sáez A, Rodríguez de Cía J, del Pozo E, Vega-Piris L, Soto-Fernández S, Lo Iacono O, Miquilena-Colina ME.

Liver Int. 2015 Aug;35(8):1983-91. doi: 10.1111/liv.12813. Epub 2015 Mar 5.

PMID:
25708133
50.

Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease.

Bontempi IA, Vicco MH, Cabrera G, Villar SR, González FB, Roggero EA, Ameloot P, Callewaert N, Pérez AR, Marcipar IS.

Vaccine. 2015 Mar 3;33(10):1274-83. doi: 10.1016/j.vaccine.2015.01.044. Epub 2015 Jan 25.

PMID:
25625671

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