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Items: 33

1.

Ex vivo and in vivo effects of arsenite on GST and ABCC2 activity and expression in the middle intestine of the rainbow trout Oncorhynchus mykiss.

Painefilú JC, Pascual MM, Bieczynski F, Laspoumaderes C, González C, Villanueva SSM, Luquet CM.

Comp Biochem Physiol C Toxicol Pharmacol. 2019 Nov;225:108566. doi: 10.1016/j.cbpc.2019.108566. Epub 2019 Jul 10.

PMID:
31301398
2.

Reversion of down-regulation of intestinal multidrug resistance-associated protein 2 in fructose-fed rats by geraniol and vitamin C: Potential role of inflammatory response and oxidative stress.

Zecchinati F, Barranco MM, Arana MR, Tocchetti GN, Domínguez CJ, Perdomo VG, Ruiz ML, Mottino AD, García F, Villanueva SSM.

J Nutr Biochem. 2019 Jun;68:7-15. doi: 10.1016/j.jnutbio.2019.03.002. Epub 2019 Mar 19.

PMID:
31005848
3.

Inhibition of multidrug resistance-associated protein 2 (MRP2) activity by the contraceptive nomegestrol acetate in HepG2 and Caco-2 cells.

Tocchetti GN, Domínguez CJ, Zecchinati F, Arana MR, Ruiz ML, Villanueva SSM, Mottino AD, Weiss J, Rigalli JP.

Eur J Pharm Sci. 2018 Sep 15;122:205-213. doi: 10.1016/j.ejps.2018.07.017. Epub 2018 Jul 6.

PMID:
29981893
4.

Biphasic modulation of cAMP levels by the contraceptive nomegestrol acetate. Impact on P-glycoprotein expression and activity in hepatic cells.

Tocchetti GN, Domínguez CJ, Zecchinati F, Arana MR, Ruiz ML, Villanueva SSM, Weiss J, Mottino AD, Rigalli JP.

Biochem Pharmacol. 2018 Aug;154:118-126. doi: 10.1016/j.bcp.2018.04.023. Epub 2018 Apr 21.

PMID:
29684377
5.

Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-D-glucuronide in rat intestine and Caco-2 cells.

Tocchetti GN, Arias A, Arana MR, Rigalli JP, Domínguez CJ, Zecchinati F, Ruiz ML, Villanueva SSM, Mottino AD.

Arch Toxicol. 2018 Feb;92(2):777-788. doi: 10.1007/s00204-017-2092-9. Epub 2017 Oct 20.

PMID:
29052767
6.

Glucagon-like peptide 2 prevents down-regulation of intestinal multidrug resistance-associated protein 2 and P-glycoprotein in endotoxemic rats.

Arana MR, Tocchetti GN, Zecchinati F, Londero AS, Dominguez C, Perdomo V, Rigalli JP, Villanueva SSM, Mottino AD.

Toxicology. 2017 Sep 1;390:22-31. doi: 10.1016/j.tox.2017.08.007. Epub 2017 Aug 23.

PMID:
28842383
7.

Intestinal multidrug resistance-associated protein 2 is down-regulated in fructose-fed rats.

Londero AS, Arana MR, Perdomo VG, Tocchetti GN, Zecchinati F, Ghanem CI, Ruiz ML, Rigalli JP, Mottino AD, García F, Villanueva SSM.

J Nutr Biochem. 2017 Feb;40:178-186. doi: 10.1016/j.jnutbio.2016.11.002. Epub 2016 Nov 9.

PMID:
27915161
8.

Alterations in the intestine of Patagonian silverside (Odontesthes hatcheri) exposed to microcystin-LR: Changes in the glycosylation pattern of the intestinal wall and inhibition of multidrug resistance proteins efflux activity.

Bieczynski F, Torres WD, Painefilu JC, Castro JM, Bianchi VA, Frontera JL, Paz DA, González C, Martín A, Villanueva SS, Luquet CM.

Aquat Toxicol. 2016 Sep;178:106-17. doi: 10.1016/j.aquatox.2016.07.016. Epub 2016 Jul 25.

PMID:
27474942
9.

Modulation of expression and activity of intestinal multidrug resistance-associated protein 2 by xenobiotics.

Tocchetti GN, Rigalli JP, Arana MR, Villanueva SSM, Mottino AD.

Toxicol Appl Pharmacol. 2016 Jul 15;303:45-57. doi: 10.1016/j.taap.2016.05.002. Epub 2016 May 4. Review.

PMID:
27155371
10.

Physiological and pathophysiological factors affecting the expression and activity of the drug transporter MRP2 in intestine. Impact on its function as membrane barrier.

Arana MR, Tocchetti GN, Rigalli JP, Mottino AD, Villanueva SS.

Pharmacol Res. 2016 Jul;109:32-44. doi: 10.1016/j.phrs.2016.04.014. Epub 2016 Apr 22. Review.

PMID:
27109321
11.

The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters.

Rigalli JP, Tocchetti GN, Arana MR, Villanueva SS, Catania VA, Theile D, Ruiz ML, Weiss J.

Cancer Lett. 2016 Jun 28;376(1):165-72. doi: 10.1016/j.canlet.2016.03.040. Epub 2016 Mar 24.

PMID:
27033456
12.

Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance.

Arana MR, Tocchetti GN, Domizi P, Arias A, Rigalli JP, Ruiz ML, Luquita MG, Banchio C, Mottino AD, Villanueva SSM.

Toxicol Appl Pharmacol. 2015 Sep 1;287(2):178-190. doi: 10.1016/j.taap.2015.06.003. Epub 2015 Jun 3.

PMID:
26049102
13.

Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity.

Rigalli JP, Ciriaci N, Arias A, Ceballos MP, Villanueva SS, Luquita MG, Mottino AD, Ghanem CI, Catania VA, Ruiz ML.

PLoS One. 2015 Mar 17;10(3):e0119502. doi: 10.1371/journal.pone.0119502. eCollection 2015.

14.

Cellular transport of microcystin-LR in rainbow trout (Oncorhynchus mykiss) across the intestinal wall: possible involvement of multidrug resistance-associated proteins.

Bieczynski F, De Anna JS, Pirez M, Brena BM, Villanueva SS, Luquet CM.

Aquat Toxicol. 2014 Sep;154:97-106. doi: 10.1016/j.aquatox.2014.05.003. Epub 2014 May 12.

PMID:
24865614
15.

Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.

Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, Vore M, Catania VA, Mottino AD.

Toxicology. 2014 Jun 5;320:46-55. doi: 10.1016/j.tox.2014.03.007. Epub 2014 Mar 28.

PMID:
24685904
16.

Modulation of biotransformation systems and ABC transporters by benznidazole in rats.

Perdomo VG, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Echenique CG, Catania VA.

Antimicrob Agents Chemother. 2013 Oct;57(10):4894-902. doi: 10.1128/AAC.02531-12. Epub 2013 Jul 22.

17.

Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17α-ethynylestradiol. Role of activator protein-1.

Ruiz ML, Rigalli JP, Arias A, Villanueva SS, Banchio C, Vore M, Mottino AD, Catania VA.

Biochem Pharmacol. 2013 Aug 1;86(3):401-9. doi: 10.1016/j.bcp.2013.05.025. Epub 2013 Jun 6.

PMID:
23747343
18.

Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor.

Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.

PLoS Negl Trop Dis. 2012;6(12):e1951. doi: 10.1371/journal.pntd.0001951. Epub 2012 Dec 13.

19.

Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Villanueva SS, Perdomo VG, Ruiz ML, Rigalli JP, Arias A, Luquita MG, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2012 Jul;40(7):1252-8. doi: 10.1124/dmd.111.044339. Epub 2012 Mar 27.

20.

Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells.

Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA.

Toxicology. 2011 Jul 11;285(1-2):18-24. doi: 10.1016/j.tox.2011.03.015. Epub 2011 Apr 1.

PMID:
21459122
21.

Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat.

Villanueva SS, Arias A, Ruiz ML, Rigalli JP, Pellegrino JM, Vore M, Catania VA, Mottino AD.

J Pharmacol Exp Ther. 2010 Nov;335(2):332-41. doi: 10.1124/jpet.110.171041. Epub 2010 Aug 18.

PMID:
20719938
22.

Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.

Ruiz ML, Villanueva SS, Luquita MG, Pellegrino JM, Rigalli JP, Arias A, Sánchez Pozzi EJ, Mottino AD, Catania VA.

Eur J Pharmacol. 2009 Nov 25;623(1-3):103-6. doi: 10.1016/j.ejphar.2009.09.014. Epub 2009 Sep 17.

PMID:
19766108
23.

Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose.

Ghanem CI, Ruiz ML, Villanueva SS, Luquita M, Llesuy S, Catania VA, Bengochea LA, Mottino AD.

Biochem Pharmacol. 2009 May 15;77(10):1621-8. doi: 10.1016/j.bcp.2009.02.006. Epub 2009 Feb 23.

PMID:
19426699
24.

Regulation of expression and activity of rat intestinal multidrug resistance-associated protein 2 by cholestatic estrogens.

Arias A, Villanueva SS, Ruiz ML, Luquita MG, Veggi LM, Pellegrino JM, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2009 Jun;37(6):1277-85. doi: 10.1124/dmd.108.025643. Epub 2009 Mar 19.

PMID:
19299525
25.

Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats.

Villanueva SS, Ruiz ML, Ghanem CI, Luquita MG, Catania VA, Mottino AD.

Drug Metab Dispos. 2008 Mar;36(3):475-80. Epub 2007 Dec 20.

PMID:
18096675
26.

Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2.

Ruiz ML, Villanueva SS, Luquita MG, Ikushiro S, Mottino AD, Catania VA.

Drug Metab Dispos. 2007 Nov;35(11):2060-6. Epub 2007 Aug 8.

PMID:
17686906
27.

Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats.

Villanueva SS, Ruiz ML, Soroka CJ, Cai SY, Luquita MG, Torres AM, Sánchez Pozzi EJ, Pellegrino JM, Boyer JL, Catania VA, Mottino AD.

Drug Metab Dispos. 2006 Aug;34(8):1301-9. Epub 2006 May 5.

PMID:
16679389
28.

Ethynylestradiol increases expression and activity of rat liver MRP3.

Ruiz ML, Villanueva SS, Luquita MG, Vore M, Mottino AD, Catania VA.

Drug Metab Dispos. 2006 Jun;34(6):1030-4. Epub 2006 Mar 22.

PMID:
16554369
29.

Shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats.

Ghanem CI, Ruiz ML, Villanueva SS, Luquita MG, Catania VA, Jones B, Bengochea LA, Vore M, Mottino AD.

J Pharmacol Exp Ther. 2005 Dec;315(3):987-95. Epub 2005 Aug 18.

PMID:
16109740
30.

Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.

Ruiz ML, Villanueva SS, Luquita MG, Sánchez-Pozzi EJ, Crocenzi FA, Pellegrino JM, Ochoa JE, Vore M, Mottino AD, Catania VA.

Biochem Pharmacol. 2005 Feb 1;69(3):531-9. Epub 2004 Dec 15.

PMID:
15652244
31.

Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.

Villanueva SS, Ruiz ML, Luquita MG, Sánchez Pozzi EJ, Catania VA, Mottino AD.

Toxicol Sci. 2005 Mar;84(1):4-11. Epub 2004 Dec 8.

PMID:
15590889
32.

Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein.

Ghanem CI, Gómez PC, Arana MC, Perassolo M, Ruiz ML, Villanueva SS, Ochoa EJ, Catania VA, Bengochea LA, Mottino AD.

Biochem Pharmacol. 2004 Aug 15;68(4):791-8.

PMID:
15276087
33.

Co-regulation of expression of phase II metabolizing enzymes and multidrug resistance-associated protein 2.

Catania VA, Sánchez Pozzi EJ, Luquita MG, Ruiz ML, Villanueva SS, Jones B, Mottino AD.

Ann Hepatol. 2004 Jan-Mar;3(1):11-7. Review.

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