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Items: 1 to 50 of 643

1.

Phenotype-based screens with conformation-specific inhibitors reveal p38 gamma and delta as targets for HCC polypharmacology.

Yu JX, Craig AJ, Duffy ME, Villacorta-Martin C, Miguela V, Ruiz de Galarreta M, Scopton AP, Silber L, Maldonado AY, Rialdi A, Guccione E, Lujambio A, Villanueva A, Dar AC.

Mol Cancer Ther. 2019 Jun 18. pii: molcanther.0571.2018. doi: 10.1158/1535-7163.MCT-18-0571. [Epub ahead of print]

PMID:
31213506
2.

LOSS OF TLD SIGNAL DUE TO HIGH TEMPERATURE ENVIRONMENTAL CONDITIONS.

Villanueva A, Goddard B.

Radiat Prot Dosimetry. 2019 Jun 17. pii: ncz130. doi: 10.1093/rpd/ncz130. [Epub ahead of print]

PMID:
31204777
3.

β-catenin activation promotes immune escape and resistance to anti-PD-1 therapy in hepatocellular carcinoma.

Ruiz de Galarreta M, Bresnahan E, Molina-Sanchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A.

Cancer Discov. 2019 Jun 11. pii: CD-19-0074. doi: 10.1158/2159-8290.CD-19-0074. [Epub ahead of print]

PMID:
31186238
4.

The Impact of Translational Research in Hepatology.

von Felden J, Craig AJ, Villanueva A.

Clin Liver Dis (Hoboken). 2019 Feb 21;13(1):29-33. doi: 10.1002/cld.805. eCollection 2019 Jan. Review. No abstract available.

5.

Mitohormesis Primes Tumor Invasion and Metastasis.

Kenny TC, Craig AJ, Villanueva A, Germain D.

Cell Rep. 2019 May 21;27(8):2292-2303.e6. doi: 10.1016/j.celrep.2019.04.095.

6.

Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2.

Slocum E, Craig A, Villanueva A, Germain D.

Breast Cancer Res. 2019 May 2;21(1):56. doi: 10.1186/s13058-019-1142-z.

7.

Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans.

DeRossi C, Bambino K, Morrison J, Sakarin I, Villacorta-Martin C, Zhang C, Ellis JL, Fiel MI, Ybanez M, Lee YA, Huang KL, Yin C, Sakaguchi TF, Friedman SL, Villanueva A, Chu J.

Hepatology. 2019 Apr 23. doi: 10.1002/hep.30677. [Epub ahead of print]

PMID:
31016744
8.

The Role of Participants in a Medical Information Commons.

Majumder MA, Bollinger JM, Villanueva AG, Deverka PA, Koenig BA.

J Law Med Ethics. 2019 Mar;47(1):51-61. doi: 10.1177/1073110519840484.

PMID:
30994075
9.

Hopeful and Concerned: Public Input on Building a Trustworthy Medical Information Commons.

Deverka PA, Gilmore D, Richmond J, Smith Z, Mangrum R, Koenig BA, Cook-Deegan R, Villanueva AG, Majumder MA, McGuire AL.

J Law Med Ethics. 2019 Mar;47(1):70-87. doi: 10.1177/1073110519840486.

PMID:
30994071
10.

Characterizing the Biomedical Data-Sharing Landscape.

Villanueva AG, Cook-Deegan R, Koenig BA, Deverka PA, Versalovic E, McGuire AL, Majumder MA.

J Law Med Ethics. 2019 Mar;47(1):21-30. doi: 10.1177/1073110519840481.

PMID:
30994069
11.

Importance of Participant-Centricity and Trust for a Sustainable Medical Information Commons.

McGuire AL, Majumder MA, Villanueva AG, Bardill J, Bollinger JM, Boerwinkle E, Bubela T, Deverka PA, Evans BJ, Garrison NA, Glazer D, Goldstein MM, Greely HT, Kahn SD, Knoppers BM, Koenig BA, Lambright JM, Mattison JE, O'Donnell C, Rai AK, Rodriguez LL, Simoncelli T, Terry SF, Thorogood AM, Watson MS, Wilbanks JT, Cook-Deegan R.

J Law Med Ethics. 2019 Mar;47(1):12-20. doi: 10.1177/1073110519840480.

PMID:
30994067
12.

What is a Medical Information Commons?

Bollinger JM, Zuk PD, Majumder MA, Versalovic E, Villanueva AG, Hsu RL, McGuire AL, Cook-Deegan R.

J Law Med Ethics. 2019 Mar;47(1):41-50. doi: 10.1177/1073110519840483.

PMID:
30994065
13.

Genomic Data-Sharing Practices.

Villanueva AG, Cook-Deegan R, Robinson JO, McGuire AL, Majumder MA.

J Law Med Ethics. 2019 Mar;47(1):31-40. doi: 10.1177/1073110519840482.

PMID:
30994063
14.

Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer.

Guillén Díaz-Maroto N, Sanz-Pamplona R, Berdiel-Acer M, Cimas FJ, García E, Gonçalves-Ribeiro S, Albert N, Garcia-Vicién G, Capella G, Moreno V, Salazar R, Villanueva A, Molleví DG.

Clin Cancer Res. 2019 Apr 12. doi: 10.1158/1078-0432.CCR-18-3957. [Epub ahead of print]

PMID:
30979739
15.

Hepatocellular Carcinoma.

Villanueva A.

N Engl J Med. 2019 Apr 11;380(15):1450-1462. doi: 10.1056/NEJMra1713263. Review. No abstract available.

PMID:
30970190
16.

Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival.

Llovet JM, Montal R, Villanueva A.

J Hepatol. 2019 Jun;70(6):1262-1277. doi: 10.1016/j.jhep.2019.01.028. Epub 2019 Mar 31. Review.

PMID:
30943423
17.

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus.

Prieto CP, Casas BS, Falcón P, Villanueva A, Lois P, Lattus J, Palma V.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1408. doi: 10.3390/ijms20061408.

18.

Long-term corneal multifocal stability following a presbyLASIK technique analysed by a light propagation algorithm.

Villanueva A, Vargas V, Mas D, Torky M, Alió JL.

Clin Exp Optom. 2019 Mar 13. doi: 10.1111/cxo.12883. [Epub ahead of print]

PMID:
30866063
19.

Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.

Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, de Moura MC, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M, Yanes O, Zorzano A, Moutinho C, Esteller M.

JCI Insight. 2019 Mar 7;5. pii: 125888. doi: 10.1172/jci.insight.125888.

20.

A phenotypical map of disseminated hepatocellular carcinoma suggests clonal constraints in metastatic sites.

Martins-Filho SN, Alves VAF, Wakamatsu A, Maeda M, Craig AJ, Assato AK, Villacorta-Martin C, D'Avola D, Labgaa I, Carrilho FJ, Thung SN, Villanueva A.

Histopathology. 2019 Apr;74(5):718-730. doi: 10.1111/his.13809. Epub 2019 Feb 21.

PMID:
30636011
21.

General Assembly, Prevention, Wound Management: Proceedings of International Consensus on Orthopedic Infections.

Al-Houraibi RK, Aalirezaie A, Adib F, Anoushiravani A, Bhashyam A, Binlaksar R, Blevins K, Bonanzinga T, Chih-Kuo F, Cordova M, Deirmengian GK, Fillingham Y, Frenkel T, Gomez J, Gundtoft P, Harris MA, Harris M, Heller S, Jennings JA, Jiménez-Garrido C, Karam JA, Khlopas A, Klement MR, Komnos G, Krebs V, Lachiewicz P, Miller AO, Mont MA, Montañez E, Romero CA, Schwarzkopf R, Shaffer A, Sharkey PF, Smith BM, Sodhi N, Thienpont E, Villanueva AO, Yazdi H.

J Arthroplasty. 2019 Feb;34(2S):S157-S168. doi: 10.1016/j.arth.2018.09.066. Epub 2018 Oct 22. No abstract available.

PMID:
30360978
22.

Prevalence of chronic obstructive pulmonary disease (COPD) among Congolese cement workers exposed to cement dust, in Kongo Central Province.

Mbelambela EP, Eitoku M, Muchanga SMJ, Villanueva AF, Hirota R, Pulphus TY, Sokolo GJ, Yasumitsu-Lovell K, Komori K, Suganuma N.

Environ Sci Pollut Res Int. 2018 Dec;25(35):35074-35083. doi: 10.1007/s11356-018-3401-4. Epub 2018 Oct 16.

PMID:
30328036
23.

Role of circulating tumor DNA to help decision-making in hepatocellular carcinoma.

von Felden J, Craig AJ, Villanueva A.

Oncoscience. 2018 Aug 22;5(7-8):209-211. doi: 10.18632/oncoscience.446. eCollection 2018 Jul. No abstract available.

24.

The Educational Consequences of Adolescent Childbearing and Union Formation in Brazil.

Marteleto LJ, Villanueva A.

Stud Fam Plann. 2018 Aug 31. doi: 10.1111/sifp.12071. [Epub ahead of print]

PMID:
30168597
25.

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells.

Villanueva AA, Puvogel S, Lois P, Muñoz-Palma E, Ramírez Orellana M, Lubieniecki F, Casco Claro F, Gallegos I, García-Castro J, Sanchez-Gomez P, Torres VA, Palma V.

Cell Adh Migr. 2019 Dec;13(1):33-40. doi: 10.1080/19336918.2018.1506652. Epub 2018 Aug 30.

26.

Patient-Derived Xenograft Models for Endometrial Cancer Research.

Moiola CP, Lopez-Gil C, Cabrera S, Garcia A, Van Nyen T, Annibali D, Fonnes T, Vidal A, Villanueva A, Matias-Guiu X, Krakstad C, Amant F, Gil-Moreno A, Colas E.

Int J Mol Sci. 2018 Aug 17;19(8). pii: E2431. doi: 10.3390/ijms19082431. Review.

27.

Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial.

Pinyol R, Montal R, Bassaganyas L, Sia D, Takayama T, Chau GY, Mazzaferro V, Roayaie S, Lee HC, Kokudo N, Zhang Z, Torrecilla S, Moeini A, Rodriguez-Carunchio L, Gane E, Verslype C, Croitoru AE, Cillo U, de la Mata M, Lupo L, Strasser S, Park JW, Camps J, Solé M, Thung SN, Villanueva A, Pena C, Meinhardt G, Bruix J, Llovet JM.

Gut. 2019 Jun;68(6):1065-1075. doi: 10.1136/gutjnl-2018-316408. Epub 2018 Aug 14.

28.

Evaluation of oncogenic cysteinyl leukotriene receptor 2 as a therapeutic target for uveal melanoma.

Slater K, Hoo PS, Buckley AM, Piulats JM, Villanueva A, Portela A, Kennedy BN.

Cancer Metastasis Rev. 2018 Sep;37(2-3):335-345. doi: 10.1007/s10555-018-9751-z. Review.

PMID:
30094568
29.

The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.

Sánchez-Botet A, Gasa L, Quandt E, Hernández-Ortega S, Jiménez J, Mezquita P, Carrasco-García MÀ, Kron SJ, Vidal A, Villanueva A, Ribeiro MPC, Clotet J.

Sci Rep. 2018 Aug 7;8(1):11797. doi: 10.1038/s41598-018-30307-x.

30.

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma.

D'Avola D, Villacorta-Martin C, Martins-Filho SN, Craig A, Labgaa I, von Felden J, Kimaada A, Bonaccorso A, Tabrizian P, Hartmann BM, Sebra R, Schwartz M, Villanueva A.

Sci Rep. 2018 Aug 1;8(1):11570. doi: 10.1038/s41598-018-30047-y.

31.

Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.

López-Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng JH, Yan B, Gonzalez-Perez A, Junttila MR, Iglesias M, Torres F, Albanell J, Villanueva A, Bigas A, Siebel CW, Espinosa L.

Nat Commun. 2018 Jul 31;9(1):2992. doi: 10.1038/s41467-018-05385-0.

32.

Circular RNA CpG island hypermethylation-associated silencing in human cancer.

Ferreira HJ, Davalos V, de Moura MC, Soler M, Perez-Salvia M, Bueno-Costa A, Setien F, Moran S, Villanueva A, Esteller M.

Oncotarget. 2018 Jun 26;9(49):29208-29219. doi: 10.18632/oncotarget.25673. eCollection 2018 Jun 26.

33.

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence.

Puig I, Tenbaum SP, Chicote I, Arqués O, Martínez-Quintanilla J, Cuesta-Borrás E, Ramírez L, Gonzalo P, Soto A, Aguilar S, Eguizabal C, Caratù G, Prat A, Argilés G, Landolfi S, Casanovas O, Serra V, Villanueva A, Arroyo AG, Terracciano L, Nuciforo P, Seoane J, Recio JA, Vivancos A, Dienstmann R, Tabernero J, Palmer HG.

J Clin Invest. 2018 Aug 31;128(9):3887-3905. doi: 10.1172/JCI96393. Epub 2018 Aug 6.

34.

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma.

Pérez-Salvia M, Aldaba E, Vara Y, Fabre M, Ferrer C, Masdeu C, Zubia A, Sebastian ES, Otaegui D, Llinàs-Arias P, Rosselló-Tortella M, Berdasco M, Moutinho C, Setien F, Villanueva A, González-Barca E, Muncunill J, Navarro JT, Piris MA, Cossio FP, Esteller M.

Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241. Epub 2018 Jun 7. No abstract available.

35.

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

Mainardi S, Mulero-Sánchez A, Prahallad A, Germano G, Bosma A, Krimpenfort P, Lieftink C, Steinberg JD, de Wit N, Gonçalves-Ribeiro S, Nadal E, Bardelli A, Villanueva A, Bernards R.

Nat Med. 2018 Jul;24(7):961-967. doi: 10.1038/s41591-018-0023-9. Epub 2018 May 28.

PMID:
29808006
36.

Corneal Stability following Hyperopic LASIK with Advanced Laser Ablation Profiles Analyzed by a Light Propagation Study.

Gharaibeh AM, Villanueva A, Mas D, Espinosa J, Alió JL.

J Ophthalmol. 2018 Mar 28;2018:3060939. doi: 10.1155/2018/3060939. eCollection 2018.

37.

Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin.

García-Rodríguez FJ, Martínez-Fernández C, Brena D, Kukhtar D, Serrat X, Nadal E, Boxem M, Honnen S, Miranda-Vizuete A, Villanueva A, Cerón J.

Dis Model Mech. 2018 Jun 21;11(6). pii: dmm033506. doi: 10.1242/dmm.033506.

38.

Concurrent Spontaneous Pneumomediastinum and Pneumorrhachis.

Heckman AJ, Mohseni M, Villanueva A, Cowart JB, Graham CG.

J Emerg Med. 2018 Jun;54(6):e117-e120. doi: 10.1016/j.jemermed.2018.02.036. Epub 2018 Apr 21.

PMID:
29685465
39.

Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance.

Ruiz de Garibay G, Mateo F, Stradella A, Valdés-Mas R, Palomero L, Serra-Musach J, Puente DA, Díaz-Navarro A, Vargas-Parra G, Tornero E, Morilla I, Farré L, Martinez-Iniesta M, Herranz C, McCormack E, Vidal A, Petit A, Soler T, Lázaro C, Puente XS, Villanueva A, Pujana MA.

Dis Model Mech. 2018 May 18;11(5). pii: dmm032292. doi: 10.1242/dmm.032292.

40.

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.

Labgaa I, Villacorta-Martin C, D'Avola D, Craig AJ, von Felden J, Martins-Filho SN, Sia D, Stueck A, Ward SC, Fiel MI, Mahajan M, Tabrizian P, Thung SN, Ang C, Friedman SL, Llovet JM, Schwartz M, Villanueva A.

Oncogene. 2018 Jul;37(27):3740-3752. doi: 10.1038/s41388-018-0206-3. Epub 2018 Apr 9.

41.

Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.

Piulats JM, Vidal A, García-Rodríguez FJ, Muñoz C, Nadal M, Moutinho C, Martínez-Iniesta M, Mora J, Figueras A, Guinó E, Padullés L, Aytés À, Molleví DG, Puertas S, Martínez-Fernández C, Castillo W, Juliachs M, Moreno V, Muñoz P, Stefanovic M, Pujana MA, Condom E, Esteller M, Germà JR, Capella G, Farré L, Morales A, Viñals F, García-Del-Muro X, Cerón J, Villanueva A.

Clin Cancer Res. 2018 Aug 1;24(15):3755-3766. doi: 10.1158/1078-0432.CCR-17-1898. Epub 2018 Apr 4.

PMID:
29618620
42.

70-Year-Old Woman With Sudden Onset of Chest Pain and Diaphoresis.

Villanueva A, Shaughnessy G, Ung S.

Mayo Clin Proc. 2018 Apr;93(4):e35-e39. doi: 10.1016/j.mayocp.2017.04.018. Epub 2018 Feb 1. No abstract available.

PMID:
29395355
43.

Focused Transhepatic Electroporation Mediated by Hypersaline Infusion through the Portal Vein in Rat Model. Preliminary Results on Differential Conductivity.

Pañella C, Castellví Q, Moll X, Quesada R, Villanueva A, Iglesias M, Naranjo D, Sánchez-Velázquez P, Andaluz A, Grande L, Ivorra A, Burdío F.

Radiol Oncol. 2017 Nov 29;51(4):415-421. doi: 10.1515/raon-2017-0051. eCollection 2017 Dec.

44.

24-Year-Old Man With Acute Chest Pain.

Trautman CL, Villanueva A, Stancampiano FF.

Mayo Clin Proc. 2017 Dec;92(12):1850-1854. doi: 10.1016/j.mayocp.2017.02.022. No abstract available.

PMID:
29202941
45.

A Role for CXCR4 in Peritoneal and Hematogenous Ovarian Cancer Dissemination.

Figueras A, Alsina-Sanchís E, Lahiguera Á, Abreu M, Muinelo-Romay L, Moreno-Bueno G, Casanovas O, Graupera M, Matias-Guiu X, Vidal A, Villanueva A, Viñals F.

Mol Cancer Ther. 2018 Feb;17(2):532-543. doi: 10.1158/1535-7163.MCT-17-0643. Epub 2017 Nov 16.

46.

Radioresistance of mesenchymal glioblastoma initiating cells correlates with patient outcome and is associated with activation of inflammatory program.

Stanzani E, Martínez-Soler F, Mateos TM, Vidal N, Villanueva A, Pujana MA, Serra-Musach J, de la Iglesia N, Giménez-Bonafé P, Tortosa A.

Oncotarget. 2017 Jun 3;8(43):73640-73653. doi: 10.18632/oncotarget.18363. eCollection 2017 Sep 26.

47.

Divergent evolutionary trajectories in transplanted tumor models.

Villacorta-Martin C, Craig AJ, Villanueva A.

Nat Genet. 2017 Oct 27;49(11):1565-1566. doi: 10.1038/ng.3983.

PMID:
29074950
48.

Molecular profiling of liver cancer heterogeneity.

Craig AJ, von Felden J, Villanueva A.

Discov Med. 2017 Sep;24(131):117-125. Review.

49.

Sonic hedgehog (SHH) signaling improves the angiogenic potential of Wharton's jelly-derived mesenchymal stem cells (WJ-MSC).

Zavala G, Prieto CP, Villanueva AA, Palma V.

Stem Cell Res Ther. 2017 Sep 29;8(1):203. doi: 10.1186/s13287-017-0653-8.

50.

Dual MET and ERBB inhibition overcomes intratumor plasticity in osimertinib-resistant-advanced non-small-cell lung cancer (NSCLC).

Martinez-Marti A, Felip E, Matito J, Mereu E, Navarro A, Cedrés S, Pardo N, Martinez de Castro A, Remon J, Miquel JM, Guillaumet-Adkins A, Nadal E, Rodriguez-Esteban G, Arqués O, Fasani R, Nuciforo P, Heyn H, Villanueva A, Palmer HG, Vivancos A.

Ann Oncol. 2017 Oct 1;28(10):2451-2457. doi: 10.1093/annonc/mdx396.

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