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Items: 1 to 50 of 658

1.

Utility of In Vitro Mutagenesis of RPE65 Protein for Verification of Mutational Pathogenicity Before Gene Therapy.

Yang U, Gentleman S, Gai X, Gorin MB, Borchert MS, Lee TC, Villanueva A, Koenekoop R, Maguire AM, Bennett J, Redmond TM, Nagiel A.

JAMA Ophthalmol. 2019 Oct 3:1-9. doi: 10.1001/jamaophthalmol.2019.3914. [Epub ahead of print]

PMID:
31580392
2.

Neuroprotective protein hydrolysates from hemp (Cannabis sativa L.) seeds.

Rodriguez-Martin NM, Toscano R, Villanueva A, Pedroche J, Millan F, Montserrat-de la Paz S, Millan-Linares MC.

Food Funct. 2019 Oct 16;10(10):6732-6739. doi: 10.1039/c9fo01904a.

PMID:
31576391
3.

Multidrug resistance and risk factors associated with community-acquired urinary tract infections caused by Escherichia coli in Venezuela.

Guzmán M, Salazar E, Cordero V, Castro A, Villanueva A, Rodulfo H, De Donato M.

Biomedica. 2019 May 1;39(s1):96-107. doi: 10.7705/biomedica.v39i2.4030. English, Spanish.

4.

Mechanisms of Action of Drugs Effective in Hepatocellular Carcinoma.

Sarcognato S, García-Lezana T, Villanueva A.

Clin Liver Dis (Hoboken). 2019 Sep 2;14(2):62-65. doi: 10.1002/cld.810. eCollection 2019 Aug. Review. No abstract available.

5.

The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition.

Oliveira-Mateos C, Sánchez-Castillo A, Soler M, Obiols-Guardia A, Piñeyro D, Boque-Sastre R, Calleja-Cervantes ME, Castro de Moura M, Martínez-Cardús A, Rubio T, Pelletier J, Martínez-Iniesta M, Herrero-Martín D, Tirado OM, Gentilella A, Villanueva A, Esteller M, Farré L, Guil S.

Nat Commun. 2019 Sep 4;10(1):3979. doi: 10.1038/s41467-019-11910-6.

6.

Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma.

Yarchoan M, Agarwal P, Villanueva A, Rao S, Dawson LA, Llovet JM, Finn RS, Groopman JD, El-Serag HB, Monga SP, Wang XW, Karin M, Schwartz RE, Tanabe KK, Roberts LR, Gunaratne PH, Tsung A, Brown KA, Lawrence TS, Salem R, Singal AG, Kim AK, Rabiee A, Resar L, Hoshida Y, He AR, Ghoshal K, Ryan PB, Jaffee EM, Guha C, Mishra L, Coleman CN, Ahmed MM.

Cancer Res. 2019 Sep 1;79(17):4326-4330. doi: 10.1158/0008-5472.CAN-19-0803.

PMID:
31481419
7.

A novel JAK2 R564* variant in a patient with thrombocytosis.

Villanueva A, Poon KS, Gallardo CA, Chai CN, Chiu L, Yan B, Ding CSL, Yong KJ, Zhou J, Lee J, Tan K, Ong KH.

Int J Lab Hematol. 2019 Aug 23. doi: 10.1111/ijlh.13090. [Epub ahead of print] No abstract available.

PMID:
31441587
8.

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program.

Janin M, Ortiz-Barahona V, de Moura MC, Martínez-Cardús A, Llinàs-Arias P, Soler M, Nachmani D, Pelletier J, Schumann U, Calleja-Cervantes ME, Moran S, Guil S, Bueno-Costa A, Piñeyro D, Perez-Salvia M, Rosselló-Tortella M, Piqué L, Bech-Serra JJ, De La Torre C, Vidal A, Martínez-Iniesta M, Martín-Tejera JF, Villanueva A, Arias A, Cuartas I, Aransay AM, La Madrid AM, Carcaboso AM, Santa-Maria V, Mora J, Fernandez AF, Fraga MF, Aldecoa I, Pedrosa L, Graus F, Vidal N, Martínez-Soler F, Tortosa A, Carrato C, Balañá C, Boudreau MW, Hergenrother PJ, Kötter P, Entian KD, Hench J, Frank S, Mansouri S, Zadeh G, Dans PD, Orozco M, Thomas G, Blanco S, Seoane J, Preiss T, Pandolfi PP, Esteller M.

Acta Neuropathol. 2019 Aug 19. doi: 10.1007/s00401-019-02062-4. [Epub ahead of print]

PMID:
31428936
9.

Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer.

Piqué L, Martinez de Paz A, Piñeyro D, Martínez-Cardús A, Castro de Moura M, Llinàs-Arias P, Setien F, Gomez-Miragaya J, Gonzalez-Suarez E, Sigurdsson S, Jonasson JG, Villanueva A, Vidal A, Davalos V, Esteller M.

Oncogene. 2019 Aug 13. doi: 10.1038/s41388-019-0936-x. [Epub ahead of print]

PMID:
31409895
10.

Sclerosing lipogranulomatosis-induced chronic hypercalcemia and acute pancreatitis.

McRae FL, Duran SF, Villanueva A, Prodanovic E.

JAAD Case Rep. 2019 Jun 26;5(7):587-589. doi: 10.1016/j.jdcr.2019.05.003. eCollection 2019 Jul. No abstract available.

11.

IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.

Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Solé L, González-Farré M, Alonso J, Montagut C, Martinez-Iniesta M, Bertran J, Borràs E, Iglesias M, Sabidó E, Bigas A, Boulton SJ, Espinosa L.

Mol Cell. 2019 Aug 22;75(4):669-682.e5. doi: 10.1016/j.molcel.2019.05.036. Epub 2019 Jul 10.

12.

Multifunctional Albumin-Stabilized Gold Nanoclusters for the Reduction of Cancer Stem Cells.

Latorre A, Latorre A, Castellanos M, Rodriguez Diaz C, Lazaro-Carrillo A, Aguado T, Lecea M, Romero-Pérez S, Calero M, Sanchez-Puelles JM, Villanueva Á, Somoza Á.

Cancers (Basel). 2019 Jul 10;11(7). pii: E969. doi: 10.3390/cancers11070969.

13.

Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials.

Montal R, Andreu-Oller C, Bassaganyas L, Esteban-Fabró R, Moran S, Montironi C, Moeini A, Pinyol R, Peix J, Cabellos L, Villanueva A, Sia D, Mazzaferro V, Esteller M, Llovet JM.

Br J Cancer. 2019 Aug;121(4):340-343. doi: 10.1038/s41416-019-0513-7. Epub 2019 Jul 9.

PMID:
31285588
14.

Hepatocellular Carcinoma. Reply.

Villanueva A.

N Engl J Med. 2019 Jul 4;381(1):e2. doi: 10.1056/NEJMc1906565. No abstract available.

PMID:
31269387
15.

Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology.

Yu JX, Craig AJ, Duffy ME, Villacorta-Martin C, Miguela V, Ruiz de Galarreta M, Scopton AP, Silber L, Maldonado AY, Rialdi A, Guccione E, Lujambio A, Villanueva A, Dar AC.

Mol Cancer Ther. 2019 Sep;18(9):1506-1519. doi: 10.1158/1535-7163.MCT-18-0571. Epub 2019 Jun 18.

PMID:
31213506
16.

LOSS OF TLD SIGNAL DUE TO HIGH TEMPERATURE ENVIRONMENTAL CONDITIONS.

Villanueva A, Goddard B.

Radiat Prot Dosimetry. 2019 Jun 17. pii: ncz130. doi: 10.1093/rpd/ncz130. [Epub ahead of print]

PMID:
31204777
17.

β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.

Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A.

Cancer Discov. 2019 Aug;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. Epub 2019 Jun 11.

PMID:
31186238
18.

The Impact of Translational Research in Hepatology.

von Felden J, Craig AJ, Villanueva A.

Clin Liver Dis (Hoboken). 2019 Feb 21;13(1):29-33. doi: 10.1002/cld.805. eCollection 2019 Jan. Review. No abstract available.

19.

Mitohormesis Primes Tumor Invasion and Metastasis.

Kenny TC, Craig AJ, Villanueva A, Germain D.

Cell Rep. 2019 May 21;27(8):2292-2303.e6. doi: 10.1016/j.celrep.2019.04.095.

20.

Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2.

Slocum E, Craig A, Villanueva A, Germain D.

Breast Cancer Res. 2019 May 2;21(1):56. doi: 10.1186/s13058-019-1142-z.

21.

Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans.

DeRossi C, Bambino K, Morrison J, Sakarin I, Villacorta-Martin C, Zhang C, Ellis JL, Fiel MI, Ybanez M, Lee YA, Huang KL, Yin C, Sakaguchi TF, Friedman SL, Villanueva A, Chu J.

Hepatology. 2019 Apr 23. doi: 10.1002/hep.30677. [Epub ahead of print]

PMID:
31016744
22.

The Role of Participants in a Medical Information Commons.

Majumder MA, Bollinger JM, Villanueva AG, Deverka PA, Koenig BA.

J Law Med Ethics. 2019 Mar;47(1):51-61. doi: 10.1177/1073110519840484.

23.

Hopeful and Concerned: Public Input on Building a Trustworthy Medical Information Commons.

Deverka PA, Gilmore D, Richmond J, Smith Z, Mangrum R, Koenig BA, Cook-Deegan R, Villanueva AG, Majumder MA, McGuire AL.

J Law Med Ethics. 2019 Mar;47(1):70-87. doi: 10.1177/1073110519840486.

24.

Characterizing the Biomedical Data-Sharing Landscape.

Villanueva AG, Cook-Deegan R, Koenig BA, Deverka PA, Versalovic E, McGuire AL, Majumder MA.

J Law Med Ethics. 2019 Mar;47(1):21-30. doi: 10.1177/1073110519840481.

25.

Importance of Participant-Centricity and Trust for a Sustainable Medical Information Commons.

McGuire AL, Majumder MA, Villanueva AG, Bardill J, Bollinger JM, Boerwinkle E, Bubela T, Deverka PA, Evans BJ, Garrison NA, Glazer D, Goldstein MM, Greely HT, Kahn SD, Knoppers BM, Koenig BA, Lambright JM, Mattison JE, O'Donnell C, Rai AK, Rodriguez LL, Simoncelli T, Terry SF, Thorogood AM, Watson MS, Wilbanks JT, Cook-Deegan R.

J Law Med Ethics. 2019 Mar;47(1):12-20. doi: 10.1177/1073110519840480.

26.

What is a Medical Information Commons?

Bollinger JM, Zuk PD, Majumder MA, Versalovic E, Villanueva AG, Hsu RL, McGuire AL, Cook-Deegan R.

J Law Med Ethics. 2019 Mar;47(1):41-50. doi: 10.1177/1073110519840483.

27.

Genomic Data-Sharing Practices.

Villanueva AG, Cook-Deegan R, Robinson JO, McGuire AL, Majumder MA.

J Law Med Ethics. 2019 Mar;47(1):31-40. doi: 10.1177/1073110519840482.

28.

Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer.

Guillén Díaz-Maroto N, Sanz-Pamplona R, Berdiel-Acer M, Cimas FJ, García E, Gonçalves-Ribeiro S, Albert N, Garcia-Vicién G, Capella G, Moreno V, Salazar R, Villanueva A, Molleví DG.

Clin Cancer Res. 2019 Jul 15;25(14):4466-4479. doi: 10.1158/1078-0432.CCR-18-3957. Epub 2019 Apr 12.

PMID:
30979739
29.

Hepatocellular Carcinoma.

Villanueva A.

N Engl J Med. 2019 Apr 11;380(15):1450-1462. doi: 10.1056/NEJMra1713263. Review. No abstract available.

PMID:
30970190
30.

Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival.

Llovet JM, Montal R, Villanueva A.

J Hepatol. 2019 Jun;70(6):1262-1277. doi: 10.1016/j.jhep.2019.01.028. Epub 2019 Mar 31. Review.

PMID:
30943423
31.

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus.

Prieto CP, Casas BS, Falcón P, Villanueva A, Lois P, Lattus J, Palma V.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1408. doi: 10.3390/ijms20061408.

32.

Long-term corneal multifocal stability following a presbyLASIK technique analysed by a light propagation algorithm.

Villanueva A, Vargas V, Mas D, Torky M, Alió JL.

Clin Exp Optom. 2019 Sep;102(5):496-500. doi: 10.1111/cxo.12883. Epub 2019 Mar 13.

PMID:
30866063
33.

Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.

Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, de Moura MC, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M, Yanes O, Zorzano A, Moutinho C, Esteller M.

JCI Insight. 2019 Mar 7;5. pii: 125888. doi: 10.1172/jci.insight.125888.

34.

A phenotypical map of disseminated hepatocellular carcinoma suggests clonal constraints in metastatic sites.

Martins-Filho SN, Alves VAF, Wakamatsu A, Maeda M, Craig AJ, Assato AK, Villacorta-Martin C, D'Avola D, Labgaa I, Carrilho FJ, Thung SN, Villanueva A.

Histopathology. 2019 Apr;74(5):718-730. doi: 10.1111/his.13809. Epub 2019 Feb 21.

PMID:
30636011
35.

General Assembly, Prevention, Wound Management: Proceedings of International Consensus on Orthopedic Infections.

Al-Houraibi RK, Aalirezaie A, Adib F, Anoushiravani A, Bhashyam A, Binlaksar R, Blevins K, Bonanzinga T, Chih-Kuo F, Cordova M, Deirmengian GK, Fillingham Y, Frenkel T, Gomez J, Gundtoft P, Harris MA, Harris M, Heller S, Jennings JA, Jiménez-Garrido C, Karam JA, Khlopas A, Klement MR, Komnos G, Krebs V, Lachiewicz P, Miller AO, Mont MA, Montañez E, Romero CA, Schwarzkopf R, Shaffer A, Sharkey PF, Smith BM, Sodhi N, Thienpont E, Villanueva AO, Yazdi H.

J Arthroplasty. 2019 Feb;34(2S):S157-S168. doi: 10.1016/j.arth.2018.09.066. Epub 2018 Oct 22. No abstract available.

PMID:
30360978
36.

Prevalence of chronic obstructive pulmonary disease (COPD) among Congolese cement workers exposed to cement dust, in Kongo Central Province.

Mbelambela EP, Eitoku M, Muchanga SMJ, Villanueva AF, Hirota R, Pulphus TY, Sokolo GJ, Yasumitsu-Lovell K, Komori K, Suganuma N.

Environ Sci Pollut Res Int. 2018 Dec;25(35):35074-35083. doi: 10.1007/s11356-018-3401-4. Epub 2018 Oct 16.

PMID:
30328036
37.

Role of circulating tumor DNA to help decision-making in hepatocellular carcinoma.

von Felden J, Craig AJ, Villanueva A.

Oncoscience. 2018 Aug 22;5(7-8):209-211. doi: 10.18632/oncoscience.446. eCollection 2018 Jul. No abstract available.

38.

The Educational Consequences of Adolescent Childbearing and Union Formation in Brazil.

Marteleto LJ, Villanueva A.

Stud Fam Plann. 2018 Aug 31. doi: 10.1111/sifp.12071. [Epub ahead of print]

PMID:
30168597
39.

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells.

Villanueva AA, Puvogel S, Lois P, Muñoz-Palma E, Ramírez Orellana M, Lubieniecki F, Casco Claro F, Gallegos I, García-Castro J, Sanchez-Gomez P, Torres VA, Palma V.

Cell Adh Migr. 2019 Dec;13(1):33-40. doi: 10.1080/19336918.2018.1506652. Epub 2018 Aug 30.

40.

Patient-Derived Xenograft Models for Endometrial Cancer Research.

Moiola CP, Lopez-Gil C, Cabrera S, Garcia A, Van Nyen T, Annibali D, Fonnes T, Vidal A, Villanueva A, Matias-Guiu X, Krakstad C, Amant F, Gil-Moreno A, Colas E.

Int J Mol Sci. 2018 Aug 17;19(8). pii: E2431. doi: 10.3390/ijms19082431. Review.

41.

Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial.

Pinyol R, Montal R, Bassaganyas L, Sia D, Takayama T, Chau GY, Mazzaferro V, Roayaie S, Lee HC, Kokudo N, Zhang Z, Torrecilla S, Moeini A, Rodriguez-Carunchio L, Gane E, Verslype C, Croitoru AE, Cillo U, de la Mata M, Lupo L, Strasser S, Park JW, Camps J, Solé M, Thung SN, Villanueva A, Pena C, Meinhardt G, Bruix J, Llovet JM.

Gut. 2019 Jun;68(6):1065-1075. doi: 10.1136/gutjnl-2018-316408. Epub 2018 Aug 14.

42.

Evaluation of oncogenic cysteinyl leukotriene receptor 2 as a therapeutic target for uveal melanoma.

Slater K, Hoo PS, Buckley AM, Piulats JM, Villanueva A, Portela A, Kennedy BN.

Cancer Metastasis Rev. 2018 Sep;37(2-3):335-345. doi: 10.1007/s10555-018-9751-z. Review.

PMID:
30094568
43.

The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.

Sánchez-Botet A, Gasa L, Quandt E, Hernández-Ortega S, Jiménez J, Mezquita P, Carrasco-García MÀ, Kron SJ, Vidal A, Villanueva A, Ribeiro MPC, Clotet J.

Sci Rep. 2018 Aug 7;8(1):11797. doi: 10.1038/s41598-018-30307-x.

44.

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma.

D'Avola D, Villacorta-Martin C, Martins-Filho SN, Craig A, Labgaa I, von Felden J, Kimaada A, Bonaccorso A, Tabrizian P, Hartmann BM, Sebra R, Schwartz M, Villanueva A.

Sci Rep. 2018 Aug 1;8(1):11570. doi: 10.1038/s41598-018-30047-y.

45.

Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.

López-Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng JH, Yan B, Gonzalez-Perez A, Junttila MR, Iglesias M, Torres F, Albanell J, Villanueva A, Bigas A, Siebel CW, Espinosa L.

Nat Commun. 2018 Jul 31;9(1):2992. doi: 10.1038/s41467-018-05385-0.

46.

Circular RNA CpG island hypermethylation-associated silencing in human cancer.

Ferreira HJ, Davalos V, de Moura MC, Soler M, Perez-Salvia M, Bueno-Costa A, Setien F, Moran S, Villanueva A, Esteller M.

Oncotarget. 2018 Jun 26;9(49):29208-29219. doi: 10.18632/oncotarget.25673. eCollection 2018 Jun 26.

47.

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence.

Puig I, Tenbaum SP, Chicote I, Arqués O, Martínez-Quintanilla J, Cuesta-Borrás E, Ramírez L, Gonzalo P, Soto A, Aguilar S, Eguizabal C, Caratù G, Prat A, Argilés G, Landolfi S, Casanovas O, Serra V, Villanueva A, Arroyo AG, Terracciano L, Nuciforo P, Seoane J, Recio JA, Vivancos A, Dienstmann R, Tabernero J, Palmer HG.

J Clin Invest. 2018 Aug 31;128(9):3887-3905. doi: 10.1172/JCI96393. Epub 2018 Aug 6.

48.

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma.

Pérez-Salvia M, Aldaba E, Vara Y, Fabre M, Ferrer C, Masdeu C, Zubia A, Sebastian ES, Otaegui D, Llinàs-Arias P, Rosselló-Tortella M, Berdasco M, Moutinho C, Setien F, Villanueva A, González-Barca E, Muncunill J, Navarro JT, Piris MA, Cossio FP, Esteller M.

Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241. Epub 2018 Jun 7. No abstract available.

49.

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

Mainardi S, Mulero-Sánchez A, Prahallad A, Germano G, Bosma A, Krimpenfort P, Lieftink C, Steinberg JD, de Wit N, Gonçalves-Ribeiro S, Nadal E, Bardelli A, Villanueva A, Bernards R.

Nat Med. 2018 Jul;24(7):961-967. doi: 10.1038/s41591-018-0023-9. Epub 2018 May 28.

PMID:
29808006
50.

Corneal Stability following Hyperopic LASIK with Advanced Laser Ablation Profiles Analyzed by a Light Propagation Study.

Gharaibeh AM, Villanueva A, Mas D, Espinosa J, Alió JL.

J Ophthalmol. 2018 Mar 28;2018:3060939. doi: 10.1155/2018/3060939. eCollection 2018.

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