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Items: 25

1.

Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn's disease.

Chapuy L, Bsat M, Sarkizova S, Rubio M, Therrien A, Wassef E, Bouin M, Orlicka K, Weber A, Hacohen N, Villani AC, Sarfati M.

Mucosal Immunol. 2019 Jan 22. doi: 10.1038/s41385-018-0126-0. [Epub ahead of print]

PMID:
30670762
2.

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.

Sade-Feldman M, Yizhak K, Bjorgaard SL, Ray JP, de Boer CG, Jenkins RW, Lieb DJ, Chen JH, Frederick DT, Barzily-Rokni M, Freeman SS, Reuben A, Hoover PJ, Villani AC, Ivanova E, Portell A, Lizotte PH, Aref AR, Eliane JP, Hammond MR, Vitzthum H, Blackmon SM, Li B, Gopalakrishnan V, Reddy SM, Cooper ZA, Paweletz CP, Barbie DA, Stemmer-Rachamimov A, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hacohen N.

Cell. 2019 Jan 10;176(1-2):404. doi: 10.1016/j.cell.2018.12.034. No abstract available.

PMID:
30633907
3.

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection.

Ye CJ, Chen J, Villani AC, Gate RE, Subramaniam M, Bhangale T, Lee MN, Raj T, Raychowdhury R, Li W, Rogel N, Simmons S, Imboywa SH, Chipendo PI, McCabe C, Lee MH, Frohlich IY, Stranger BE, De Jager PL, Regev A, Behrens T, Hacohen N.

Genome Res. 2018 Dec;28(12):1812-1825. doi: 10.1101/gr.240390.118. Epub 2018 Nov 16.

4.

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.

Sade-Feldman M, Yizhak K, Bjorgaard SL, Ray JP, de Boer CG, Jenkins RW, Lieb DJ, Chen JH, Frederick DT, Barzily-Rokni M, Freeman SS, Reuben A, Hoover PJ, Villani AC, Ivanova E, Portell A, Lizotte PH, Aref AR, Eliane JP, Hammond MR, Vitzthum H, Blackmon SM, Li B, Gopalakrishnan V, Reddy SM, Cooper ZA, Paweletz CP, Barbie DA, Stemmer-Rachamimov A, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hacohen N.

Cell. 2018 Nov 1;175(4):998-1013.e20. doi: 10.1016/j.cell.2018.10.038. Erratum in: Cell. 2019 Jan 10;176(1-2):404.

PMID:
30388456
5.

Targeting individual cells by barcode in pooled sequence libraries.

Ranu N, Villani AC, Hacohen N, Blainey PC.

Nucleic Acids Res. 2019 Jan 10;47(1):e4. doi: 10.1093/nar/gky856.

6.

Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity.

Balan S, Arnold-Schrauf C, Abbas A, Couespel N, Savoret J, Imperatore F, Villani AC, Vu Manh TP, Bhardwaj N, Dalod M.

Cell Rep. 2018 Aug 14;24(7):1902-1915.e6. doi: 10.1016/j.celrep.2018.07.033.

7.

Systems Immunology: Learning the Rules of the Immune System.

Villani AC, Sarkizova S, Hacohen N.

Annu Rev Immunol. 2018 Apr 26;36:813-842. doi: 10.1146/annurev-immunol-042617-053035.

PMID:
29677477
8.

Corrigendum: Landscape of X chromosome inactivation across human tissues.

Tukiainen T, Villani AC, Yen A, Rivas MA, Marshall JL, Satija R, Aguirre M, Gauthier L, Fleharty M, Kirby A, Cummings BB, Castel SE, Karczewski KJ, Aguet F, Byrnes A, Consortium G, Lappalainen T, Regev A, Ardlie KG, Hacohen N, MacArthur DG.

Nature. 2018 Mar 7;555(7695):274. doi: 10.1038/nature25993.

PMID:
29517003
9.

A transcriptomic atlas of aged human microglia.

Olah M, Patrick E, Villani AC, Xu J, White CC, Ryan KJ, Piehowski P, Kapasi A, Nejad P, Cimpean M, Connor S, Yung CJ, Frangieh M, McHenry A, Elyaman W, Petyuk V, Schneider JA, Bennett DA, De Jager PL, Bradshaw EM.

Nat Commun. 2018 Feb 7;9(1):539. doi: 10.1038/s41467-018-02926-5.

10.

Landscape of X chromosome inactivation across human tissues.

Tukiainen T, Villani AC, Yen A, Rivas MA, Marshall JL, Satija R, Aguirre M, Gauthier L, Fleharty M, Kirby A, Cummings BB, Castel SE, Karczewski KJ, Aguet F, Byrnes A; GTEx Consortium; Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Enhancing GTEx (eGTEx) groups; NIH Common Fund; NIH/NCI; NIH/NHGRI; NIH/NIMH; NIH/NIDA; Biospecimen Collection Source Site—NDRI; Biospecimen Collection Source Site—RPCI; Biospecimen Core Resource—VARI; Brain Bank Repository—University of Miami Brain Endowment Bank; Leidos Biomedical—Project Management; ELSI Study; Genome Browser Data Integration &Visualization—EBI; Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Lappalainen T, Regev A, Ardlie KG, Hacohen N, MacArthur DG.

Nature. 2017 Oct 11;550(7675):244-248. doi: 10.1038/nature24265. Erratum in: Nature. 2018 Mar 7;555(7695):274.

11.

Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.

Goudot C, Coillard A, Villani AC, Gueguen P, Cros A, Sarkizova S, Tang-Huau TL, Bohec M, Baulande S, Hacohen N, Amigorena S, Segura E.

Immunity. 2017 Sep 19;47(3):582-596.e6. doi: 10.1016/j.immuni.2017.08.016.

12.

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors.

Villani AC, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager PL, Rozenblatt-Rosen O, Lane AA, Haniffa M, Regev A, Hacohen N.

Science. 2017 Apr 21;356(6335). pii: eaah4573. doi: 10.1126/science.aah4573.

13.

Single-Cell RNA Sequencing of Human T Cells.

Villani AC, Shekhar K.

Methods Mol Biol. 2017;1514:203-239.

PMID:
27787803
14.

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.

Tirosh I, Izar B, Prakadan SM, Wadsworth MH 2nd, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jané-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA.

Science. 2016 Apr 8;352(6282):189-96. doi: 10.1126/science.aad0501.

15.

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.

Griesbeck M, Ziegler S, Laffont S, Smith N, Chauveau L, Tomezsko P, Sharei A, Kourjian G, Porichis F, Hart M, Palmer CD, Sirignano M, Beisel C, Hildebrandt H, Cénac C, Villani AC, Diefenbach TJ, Le Gall S, Schwartz O, Herbeuval JP, Autran B, Guéry JC, Chang JJ, Altfeld M.

J Immunol. 2015 Dec 1;195(11):5327-36. doi: 10.4049/jimmunol.1501684. Epub 2015 Oct 30.

16.

Common genetic variants modulate pathogen-sensing responses in human dendritic cells.

Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler DA, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N.

Science. 2014 Mar 7;343(6175):1246980. doi: 10.1126/science.1246980.

17.

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.

Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N.

Nat Immunol. 2013 Feb;14(2):179-85. doi: 10.1038/ni.2509. Epub 2012 Dec 23.

18.

The contribution of genetic studies in shifting the immunopathogenesis paradigm of Crohn's disease.

Villani AC, Franchimont D.

Expert Rev Clin Immunol. 2009 Jul;5(4):361-4. doi: 10.1586/eci.09.21. No abstract available.

PMID:
20477033
19.

[Bacterial recognition of the intestinal microbial flora: an important risk factor for Crohn's disease].

Villani AC, Franchimont D.

Med Sci (Paris). 2010 Jan;26(1):36-7. doi: 10.1051/medsci/201026136. French. No abstract available.

20.

Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis.

Villani AC, Lemire M, Thabane M, Belisle A, Geneau G, Garg AX, Clark WF, Moayyedi P, Collins SM, Franchimont D, Marshall JK.

Gastroenterology. 2010 Apr;138(4):1502-13. doi: 10.1053/j.gastro.2009.12.049. Epub 2010 Jan 4.

PMID:
20044998
21.

Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis.

Villani AC, Lemire M, Louis E, Silverberg MS, Collette C, Fortin G, Nimmo ER, Renaud Y, Brunet S, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Rioux JD, Arnott ID, Wild GE, Rutgeerts P, Satsangi J, Vermeire S, Hudson TJ, Franchimont D.

PLoS One. 2009 Sep 28;4(9):e7154. doi: 10.1371/journal.pone.0007154.

22.

L-carnitine, a diet component and organic cation transporter OCTN ligand, displays immunosuppressive properties and abrogates intestinal inflammation.

Fortin G, Yurchenko K, Collette C, Rubio M, Villani AC, Bitton A, Sarfati M, Franchimont D.

Clin Exp Immunol. 2009 Apr;156(1):161-71. doi: 10.1111/j.1365-2249.2009.03879.x. Epub 2009 Jan 23.

23.

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility.

Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M, Rutgeerts P, Rioux JD, Vermeire S, Hudson TJ, Franchimont D.

Nat Genet. 2009 Jan;41(1):71-6. doi: 10.1038/ng.285. Epub 2008 Dec 21.

24.

Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: association with clinical phenotypes.

Waschke KA, Villani AC, Vermeire S, Dufresne L, Chen TC, Bitton A, Cohen A, Thomson AB, Wild GE.

Am J Gastroenterol. 2005 May;100(5):1126-33.

PMID:
15842589
25.

[Professional considerations in the administration of systems of delivery of dental care].

Villani AC.

Trib Odontol (B Aires). 1973 Jul-Sep;57(7):214-6 passim. Spanish. No abstract available.

PMID:
4524010

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