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Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors.

Lee SB, Segura-Bayona S, Villamor-Payà M, Saredi G, Todd MAM, Attolini CS, Chang TY, Stracker TH, Groth A.

Sci Adv. 2018 Aug 8;4(8):eaat4985. doi: 10.1126/sciadv.aat4985. eCollection 2018 Aug.


Molecular basis of Tousled-Like Kinase 2 activation.

Mortuza GB, Hermida D, Pedersen AK, Segura-Bayona S, López-Méndez B, Redondo P, Rüther P, Pozdnyakova I, Garrote AM, Muñoz IG, Villamor-Payà M, Jauset C, Olsen JV, Stracker TH, Montoya G.

Nat Commun. 2018 Jun 28;9(1):2535. doi: 10.1038/s41467-018-04941-y.

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