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Items: 23

1.

A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia.

Adhikari K, Mendoza-Revilla J, Sohail A, Fuentes-Guajardo M, Lampert J, Chacón-Duque JC, Hurtado M, Villegas V, Granja V, Acuña-Alonzo V, Jaramillo C, Arias W, Lozano RB, Everardo P, Gómez-Valdés J, Villamil-Ramírez H, Silva de Cerqueira CC, Hunemeier T, Ramallo V, Schuler-Faccini L, Salzano FM, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Tobin DJ, Fumagalli M, Balding D, Ruiz-Linares A.

Nat Commun. 2019 Jan 21;10(1):358. doi: 10.1038/s41467-018-08147-0.

2.

Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance.

Chacón-Duque JC, Adhikari K, Fuentes-Guajardo M, Mendoza-Revilla J, Acuña-Alonzo V, Barquera R, Quinto-Sánchez M, Gómez-Valdés J, Everardo Martínez P, Villamil-Ramírez H, Hünemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Villena M, Vásquez R, Llop E, Sandoval JR, Salazar-Granara AA, Parolin ML, Sandoval K, Peñaloza-Espinosa RI, Rangel-Villalobos H, Winkler CA, Klitz W, Bravi C, Molina J, Corach D, Barrantes R, Gomes V, Resende C, Gusmão L, Amorim A, Xue Y, Dugoujon JM, Moral P, González-José R, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Poletti G, Gallo C, Bedoya G, Rothhammer F, Balding D, Hellenthal G, Ruiz-Linares A.

Nat Commun. 2018 Dec 19;9(1):5388. doi: 10.1038/s41467-018-07748-z.

3.

Low Salivary Amylase Gene (AMY1) Copy Number Is Associated with Obesity and Gut Prevotella Abundance in Mexican Children and Adults.

León-Mimila P, Villamil-Ramírez H, López-Contreras BE, Morán-Ramos S, Macias-Kauffer LR, Acuña-Alonzo V, Del Río-Navarro BE, Salmerón J, Velazquez-Cruz R, Villarreal-Molina T, Aguilar-Salinas CA, Canizales-Quinteros S.

Nutrients. 2018 Nov 1;10(11). pii: E1607. doi: 10.3390/nu10111607.

4.

Genetic contributors to serum uric acid levels in Mexicans and their effect on premature coronary artery disease.

Macias-Kauffer LR, Villamil-Ramírez H, León-Mimila P, Jacobo-Albavera L, Posadas-Romero C, Posadas-Sánchez R, López-Contreras BE, Morán-Ramos S, Romero-Hidalgo S, Acuña-Alonzo V, Del-Río-Navarro BE, Bortolini MC, Gallo C, Bedoya G, Rothhammer F, González-Jose R, Ruiz-Linares A, Stephens CR, Velazquez-Cruz R, Fernández Del Valle-Laisequilla C, Reyes-García JG, Barranco Garduño LM, Carrasco-Portugal MDC, Flores-Murrieta FJ, Vargas-Alarcón G, Aguilar-Salinas CA, Villarreal-Molina T, Canizales-Quinteros S.

Int J Cardiol. 2019 Mar 15;279:168-173. doi: 10.1016/j.ijcard.2018.09.107. Epub 2018 Oct 1.

PMID:
30305239
5.

Composition of gut microbiota in obese and normal-weight Mexican school-age children and its association with metabolic traits.

López-Contreras BE, Morán-Ramos S, Villarruel-Vázquez R, Macías-Kauffer L, Villamil-Ramírez H, León-Mimila P, Vega-Badillo J, Sánchez-Muñoz F, Llanos-Moreno LE, Canizalez-Román A, Del Río-Navarro B, Ibarra-González I, Vela-Amieva M, Villarreal-Molina T, Ochoa-Leyva A, Aguilar-Salinas CA, Canizales-Quinteros S.

Pediatr Obes. 2018 Jun;13(6):381-388. doi: 10.1111/ijpo.12262. Epub 2017 Dec 5.

PMID:
29388394
6.

Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing.

Romero-Hidalgo S, Ochoa-Leyva A, Garcíarrubio A, Acuña-Alonzo V, Antúnez-Argüelles E, Balcazar-Quintero M, Barquera-Lozano R, Carnevale A, Cornejo-Granados F, Fernández-López JC, García-Herrera R, García-Ortíz H, Granados-Silvestre Á, Granados J, Guerrero-Romero F, Hernández-Lemus E, León-Mimila P, Macín-Pérez G, Martínez-Hernández A, Menjivar M, Morett E, Orozco L, Ortíz-López G, Pérez-Villatoro F, Rivera-Morales J, Riveros-McKay F, Villalobos-Comparán M, Villamil-Ramírez H, Villarreal-Molina T, Canizales-Quinteros S, Soberón X.

Nat Commun. 2017 Oct 18;8(1):1005. doi: 10.1038/s41467-017-01194-z.

7.

An Amino Acid Signature Associated with Obesity Predicts 2-Year Risk of Hypertriglyceridemia in School-Age Children.

Moran-Ramos S, Ocampo-Medina E, Gutierrez-Aguilar R, Macías-Kauffer L, Villamil-Ramírez H, López-Contreras BE, León-Mimila P, Vega-Badillo J, Gutierrez-Vidal R, Villarruel-Vazquez R, Serrano-Carbajal E, Del-Río-Navarro BE, Huertas-Vázquez A, Villarreal-Molina T, Ibarra-Gonzalez I, Vela-Amieva M, Aguilar-Salinas CA, Canizales-Quinteros S.

Sci Rep. 2017 Jul 17;7(1):5607. doi: 10.1038/s41598-017-05765-4.

8.

Interaction between FTO rs9939609 and the Native American-origin ABCA1 rs9282541 affects BMI in the admixed Mexican population.

Villalobos-Comparán M, Antuna-Puente B, Villarreal-Molina MT, Canizales-Quinteros S, Velázquez-Cruz R, León-Mimila P, Villamil-Ramírez H, González-Barrios JA, Merino-García JL, Thompson-Bonilla MR, Jarquin D, Sánchez-Hernández OE, Rodríguez-Arellano ME, Posadas-Romero C, Vargas-Alarcón G, Campos-Pérez F, Quiterio M, Salmerón-Castro J, Carnevale A, Romero-Hidalgo S.

BMC Med Genet. 2017 May 2;18(1):46. doi: 10.1186/s12881-017-0410-y.

9.

A combined linkage and association strategy identifies a variant near the GSTP1 gene associated with BMI in the Mexican population.

Villamil-Ramírez H, León-Mimila P, Macias-Kauffer LR, Canizalez-Román A, Villalobos-Comparán M, León-Sicairos N, Vega-Badillo J, Sánchez-Muñoz F, López-Contreras B, Morán-Ramos S, Villarreal-Molina T, Zurita LC, Campos-Pérez F, Huertas-Vazquez A, Bojalil R, Romero-Hidalgo S, Aguilar-Salinas CA, Canizales-Quinteros S.

J Hum Genet. 2017 Mar;62(3):413-418. doi: 10.1038/jhg.2016.145. Epub 2016 Nov 24.

PMID:
27881840
10.

A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation.

Adhikari K, Fuentes-Guajardo M, Quinto-Sánchez M, Mendoza-Revilla J, Camilo Chacón-Duque J, Acuña-Alonzo V, Jaramillo C, Arias W, Lozano RB, Pérez GM, Gómez-Valdés J, Villamil-Ramírez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Cheeseman M, Rosique J, Bedoya G, Rothhammer F, Headon D, González-José R, Balding D, Ruiz-Linares A.

Nat Commun. 2016 May 19;7:11616. doi: 10.1038/ncomms11616.

11.

Hepatic miR-33a/miR-144 and their target gene ABCA1 are associated with steatohepatitis in morbidly obese subjects.

Vega-Badillo J, Gutiérrez-Vidal R, Hernández-Pérez HA, Villamil-Ramírez H, León-Mimila P, Sánchez-Muñoz F, Morán-Ramos S, Larrieta-Carrasco E, Fernández-Silva I, Méndez-Sánchez N, Tovar AR, Campos-Pérez F, Villarreal-Molina T, Hernández-Pando R, Aguilar-Salinas CA, Canizales-Quinteros S.

Liver Int. 2016 Sep;36(9):1383-91. doi: 10.1111/liv.13109. Epub 2016 Mar 24.

PMID:
26945479
12.

A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features.

Adhikari K, Fontanil T, Cal S, Mendoza-Revilla J, Fuentes-Guajardo M, Chacón-Duque JC, Al-Saadi F, Johansson JA, Quinto-Sanchez M, Acuña-Alonzo V, Jaramillo C, Arias W, Barquera Lozano R, Macín Pérez G, Gómez-Valdés J, Villamil-Ramírez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Gonzalez-José R, Headon D, López-Otín C, Tobin DJ, Balding D, Ruiz-Linares A.

Nat Commun. 2016 Mar 1;7:10815. doi: 10.1038/ncomms10815.

13.

SFRP5 hepatic expression is associated with non-alcoholic liver disease in morbidly obese women.

Gutiérrez-Vidal R, Vega-Badillo J, Reyes-Fermín LM, Hernández-Pérez HA, Sánchez-Muñoz F, López-Álvarez GS, Larrieta-Carrasco E, Fernández-Silva I, Méndez-Sánchez N, Tovar AR, Villamil-Ramírez H, Mejía-Domínguez AM, Villarreal-Molina T, Hernández-Pando R, Campos-Pérez F, Aguilar-Salinas CA, Canizales-Quinteros S.

Ann Hepatol. 2015 Sep-Oct;14(5):666-74.

14.

A genome-wide association study identifies multiple loci for variation in human ear morphology.

Adhikari K, Reales G, Smith AJ, Konka E, Palmen J, Quinto-Sanchez M, Acuña-Alonzo V, Jaramillo C, Arias W, Fuentes M, Pizarro M, Barquera Lozano R, Macín Pérez G, Gómez-Valdés J, Villamil-Ramírez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Calderón R, Rosique J, Cheeseman M, Bhutta MF, Humphries SE, Gonzalez-José R, Headon D, Balding D, Ruiz-Linares A.

Nat Commun. 2015 Jun 24;6:7500. doi: 10.1038/ncomms8500.

15.

A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity.

León-Mimila P, Vega-Badillo J, Gutiérrez-Vidal R, Villamil-Ramírez H, Villareal-Molina T, Larrieta-Carrasco E, López-Contreras BE, Kauffer LR, Maldonado-Pintado DG, Méndez-Sánchez N, Tovar AR, Hernández-Pando R, Velázquez-Cruz R, Campos-Pérez F, Aguilar-Salinas CA, Canizales-Quinteros S.

Exp Mol Pathol. 2015 Apr;98(2):178-83. doi: 10.1016/j.yexmp.2015.01.012. Epub 2015 Jan 15.

PMID:
25597287
16.

PNPLA3 I148M polymorphism is associated with elevated alanine transaminase levels in Mexican Indigenous and Mestizo populations.

Larrieta-Carrasco E, Acuña-Alonzo V, Velázquez-Cruz R, Barquera-Lozano R, León-Mimila P, Villamil-Ramírez H, Menjivar M, Romero-Hidalgo S, Méndez-Sánchez N, Cárdenas V, Bañuelos-Moreno M, Flores YN, Quiterio M, Salmerón J, Sánchez-Muñoz F, Villarreal-Molina T, Aguilar-Salinas CA, Canizales-Quinteros S.

Mol Biol Rep. 2014 Jul;41(7):4705-11. doi: 10.1007/s11033-014-3341-0. Epub 2014 Apr 2.

PMID:
24691744
17.

Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults.

León-Mimila P, Villamil-Ramírez H, Villalobos-Comparán M, Villarreal-Molina T, Romero-Hidalgo S, López-Contreras B, Gutiérrez-Vidal R, Vega-Badillo J, Jacobo-Albavera L, Posadas-Romeros C, Canizalez-Román A, Río-Navarro BD, Campos-Pérez F, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S.

PLoS One. 2013 Aug 8;8(8):e70640. doi: 10.1371/journal.pone.0070640. eCollection 2013.

18.

Association of the I148M/PNPLA3 variant with elevated alanine transaminase levels in normal-weight and overweight/obese Mexican children.

Larrieta-Carrasco E, León-Mimila P, Villarreal-Molina T, Villamil-Ramírez H, Romero-Hidalgo S, Jacobo-Albavera L, Gutiérrez-Vidal R, López-Contreras BE, Guillén-Pineda LE, Sánchez-Muñoz F, Bojalil R, Mejía-Domínguez AM, Méndez-Sánchez N, Domínguez-López A, Aguilar-Salinas CA, Canizales-Quinteros S.

Gene. 2013 May 15;520(2):185-8. doi: 10.1016/j.gene.2013.03.038. Epub 2013 Mar 17.

PMID:
23510779
19.

VNN1 gene expression levels and the G-137T polymorphism are associated with HDL-C levels in Mexican prepubertal children.

Jacobo-Albavera L, Aguayo-de la Rosa PI, Villarreal-Molina T, Villamil-Ramírez H, León-Mimila P, Romero-Hidalgo S, López-Contreras BE, Sánchez-Muñoz F, Bojalil R, González-Barrios JA, Aguilar-Salinas CA, Canizales-Quinteros S.

PLoS One. 2012;7(11):e49818. doi: 10.1371/journal.pone.0049818. Epub 2012 Nov 21.

20.

Changes in peripheral blood mononuclear cells glutamine synthetase mRNA after exercise in healthy volunteers: exploring an alternative proposal for non hepatic ammonia metabolism.

Duarte-Rojo A, Torres-Vega MA, Villamil-Ramírez H, Estradas J, Domínguez-López A, Sánchez-Muñoz F, Orea-Tejeda A, Castillo-Martínez L, Miliar-García A, Macías-Rodríguez RU, Torre A.

Rev Invest Clin. 2012 Mar-Apr;64(2):164-72.

PMID:
22991778
21.

PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.

Villalobos-Comparán M, Villamil-Ramírez H, Villarreal-Molina T, Larrieta-Carrasco E, León-Mimila P, Romero-Hidalgo S, Jacobo-Albavera L, Liceaga-Fuentes AE, Campos-Pérez FJ, López-Contreras BE, Tusié-Luna T, Del Río-Navarro BE, Aguilar-Salinas CA, Canizales-Quinteros S.

PLoS One. 2012;7(6):e39037. doi: 10.1371/journal.pone.0039037. Epub 2012 Jun 21.

22.

Association of R230C ABCA1 gene variant with low HDL-C levels and abnormal HDL subclass distribution in Mexican school-aged children.

Flores-Dorantes T, Arellano-Campos O, Posadas-Sánchez R, Villarreal-Molina T, Medina-Urrutia A, Romero-Hidalgo S, Yescas-Gómez P, Pérez-Méndez O, Jorge-Galarza E, Tusié-Luna T, Villalobos-Comparán M, Jacobo-Albavera L, Villamil-Ramírez H, López-Contreras BE, Aguilar-Salinas CA, Posadas-Romero C, Canizales-Quinteros S.

Clin Chim Acta. 2010 Sep 6;411(17-18):1214-7. doi: 10.1016/j.cca.2010.04.025. Epub 2010 Apr 26.

PMID:
20427018
23.

A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.

Acuña-Alonzo V, Flores-Dorantes T, Kruit JK, Villarreal-Molina T, Arellano-Campos O, Hünemeier T, Moreno-Estrada A, Ortiz-López MG, Villamil-Ramírez H, León-Mimila P, Villalobos-Comparan M, Jacobo-Albavera L, Ramírez-Jiménez S, Sikora M, Zhang LH, Pape TD, Granados-Silvestre Mde A, Montufar-Robles I, Tito-Alvarez AM, Zurita-Salinas C, Bustos-Arriaga J, Cedillo-Barrón L, Gómez-Trejo C, Barquera-Lozano R, Vieira-Filho JP, Granados J, Romero-Hidalgo S, Huertas-Vázquez A, González-Martín A, Gorostiza A, Bonatto SL, Rodríguez-Cruz M, Wang L, Tusié-Luna T, Aguilar-Salinas CA, Lisker R, Moises RS, Menjivar M, Salzano FM, Knowler WC, Bortolini MC, Hayden MR, Baier LJ, Canizales-Quinteros S.

Hum Mol Genet. 2010 Jul 15;19(14):2877-85. doi: 10.1093/hmg/ddq173. Epub 2010 Apr 23.

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