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Items: 17

1.

Targeting Tyrosine Kinases in Acute Myeloid Leukemia: Why, Who and How?

Fernandez S, Desplat V, Villacreces A, Guitart AV, Milpied N, Pigneux A, Vigon I, Pasquet JM, Dumas PY.

Int J Mol Sci. 2019 Jul 12;20(14). pii: E3429. doi: 10.3390/ijms20143429. Review.

2.

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR.

Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Sallé D, Aksoy E, Staels B, Dombrowicz D.

Cell. 2019 Jun 27;178(1):263. doi: 10.1016/j.cell.2019.06.017. No abstract available.

PMID:
31251916
3.

Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia.

Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H, Wotherspoon DA, Sepulveda C, Vukovic M, Allen L, Sarapuu A, Tavosanis A, Guitart AV, Villacreces A, Much C, Choe J, Azar A, van de Lagemaat LN, Vernimmen D, Nehme A, Mazurier F, Somervaille TCP, Gregory RI, O'Carroll D, Kranc KR.

Cell Stem Cell. 2019 Jul 3;25(1):137-148.e6. doi: 10.1016/j.stem.2019.03.021. Epub 2019 Apr 25.

4.

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR.

Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Sallé D, Aksoy E, Staels B, Dombrowicz D.

Cell. 2019 May 16;177(5):1201-1216.e19. doi: 10.1016/j.cell.2019.03.018. Epub 2019 Apr 25. Erratum in: Cell. 2019 Jun 27;178(1):263.

5.

Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL.

Dumas PY, Naudin C, Martin-Lannerée S, Izac B, Casetti L, Mansier O, Rousseau B, Artus A, Dufossée M, Giese A, Dubus P, Pigneux A, Praloran V, Bidet A, Villacreces A, Guitart A, Milpied N, Kosmider O, Vigon I, Desplat V, Dusanter-Fourt I, Pasquet JM.

Haematologica. 2019 Oct;104(10):2017-2027. doi: 10.3324/haematol.2018.205385. Epub 2019 Mar 28.

6.

MiR-10a and HOXB4 are overexpressed in atypical myeloproliferative neoplasms.

Dumas PY, Mansier O, Prouzet-Mauleon V, Koya J, Villacreces A, Brunet de la Grange P, Luque Paz D, Bidet A, Pasquet JM, Praloran V, Salin F, Kurokawa M, Mahon FX, Cardinaud B, Lippert E.

BMC Cancer. 2018 Nov 12;18(1):1098. doi: 10.1186/s12885-018-4993-2.

7.

Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence.

Ianniciello A, Dumas PY, Drullion C, Guitart A, Villacreces A, Peytour Y, Chevaleyre J, Brunet de la Grange P, Vigon I, Desplat V, Priault M, Sbarba PD, Ivanovic Z, Mahon FX, Pasquet JM.

Oncotarget. 2017 Jun 30;8(57):96984-96992. doi: 10.18632/oncotarget.18904. eCollection 2017 Nov 14.

8.

Steady state peripheral blood provides cells with functional and metabolic characteristics of real hematopoietic stem cells.

Bourdieu A, Avalon M, Lapostolle V, Ismail S, Mombled M, Debeissat C, Guérinet M, Duchez P, Chevaleyre J, Vlaski-Lafarge M, Villacreces A, Praloran V, Ivanovic Z, Brunet de la Grange P.

J Cell Physiol. 2018 Jan;233(1):338-349. doi: 10.1002/jcp.25881. Epub 2017 Mar 28.

PMID:
28247929
9.

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.

Guitart AV, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN, Morgan M, Giles P, Sas Z, Gonzalez MV, Lawson H, Paris J, Edwards-Hicks J, Schaak K, Subramani C, Gezer D, Armesilla-Diaz A, Wills J, Easterbrook A, Coman D, So CW, O'Carroll D, Vernimmen D, Rodrigues NP, Pollard PJ, Morton NM, Finch A, Kranc KR.

J Exp Med. 2017 Mar 6;214(3):719-735. doi: 10.1084/jem.20161087. Epub 2017 Feb 15.

10.

Adult hematopoietic stem cells lacking Hif-1α self-renew normally.

Vukovic M, Sepulveda C, Subramani C, Guitart AV, Mohr J, Allen L, Panagopoulou TI, Paris J, Lawson H, Villacreces A, Armesilla-Diaz A, Gezer D, Holyoake TL, Ratcliffe PJ, Kranc KR.

Blood. 2016 Jun 9;127(23):2841-6. doi: 10.1182/blood-2015-10-677138. Epub 2016 Apr 8.

11.

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.

Vukovic M, Guitart AV, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J, Iglesias JM, Allen L, Glykofrydis F, Subramani C, Armesilla-Diaz A, Post AE, Schaak K, Gezer D, So CW, Holyoake TL, Wood A, O'Carroll D, Ratcliffe PJ, Kranc KR.

J Exp Med. 2015 Dec 14;212(13):2223-34. doi: 10.1084/jem.20150452. Epub 2015 Dec 7.

12.

CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia.

Gioia R, Trégoat C, Dumas PY, Lagarde V, Prouzet-Mauléon V, Desplat V, Sirvent A, Praloran V, Lippert E, Villacreces A, Leconet W, Robert B, Vigon I, Roche S, Mahon FX, Pasquet JM.

J Pathol. 2015 Sep;237(1):14-24. doi: 10.1002/path.4561. Epub 2015 Jun 4.

PMID:
25965880
13.

γδ T cells confer protection against murine cytomegalovirus (MCMV).

Khairallah C, Netzer S, Villacreces A, Juzan M, Rousseau B, Dulanto S, Giese A, Costet P, Praloran V, Moreau JF, Dubus P, Vermijlen D, Déchanet-Merville J, Capone M.

PLoS Pathog. 2015 Mar 6;11(3):e1004702. doi: 10.1371/journal.ppat.1004702. eCollection 2015 Mar.

14.

Busulfan administration flexibility increases the applicability of scid repopulating cell assay in NSG mouse model.

Chevaleyre J, Duchez P, Rodriguez L, Vlaski M, Villacreces A, Conrad-Lapostolle V, Praloran V, Ivanovic Z, Brunet de la Grange P.

PLoS One. 2013 Sep 17;8(9):e74361. doi: 10.1371/journal.pone.0074361. eCollection 2013.

15.

Discarded leukoreduction filters: a new source of stem cells for research, cell engineering and therapy?

Peytour Y, Villacreces A, Chevaleyre J, Ivanovic Z, Praloran V.

Stem Cell Res. 2013 Sep;11(2):736-42. doi: 10.1016/j.scr.2013.05.001. Epub 2013 May 11. Review.

16.

Very low oxygen concentration (0.1%) reveals two FDCP-Mix cell subpopulations that differ by their cell cycling, differentiation and p27KIP1 expression.

Guitart AV, Debeissat C, Hermitte F, Villacreces A, Ivanovic Z, Boeuf H, Praloran V.

Cell Death Differ. 2011 Jan;18(1):174-82. doi: 10.1038/cdd.2010.85. Epub 2010 Jul 30.

17.

Obtaining of CD34+ cells from healthy blood donors: development of a rapid and efficient procedure using leukoreduction filters.

Peytour Y, Guitart A, Villacreces A, Chevaleyre J, Lacombe F, Ivanovic Z, Praloran V.

Transfusion. 2010 Oct;50(10):2152-7. doi: 10.1111/j.1537-2995.2010.02683.x. Epub 2010 Oct 4.

PMID:
20456706

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