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Items: 17


Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness.

Aw WC, Towarnicki SG, Melvin RG, Youngson NA, Garvin MR, Hu Y, Nielsen S, Thomas T, Pickford R, Bustamante S, Vila-Sanjurjo A, Smyth GK, Ballard JWO.

PLoS Genet. 2018 Nov 6;14(11):e1007735. doi: 10.1371/journal.pgen.1007735. eCollection 2018 Nov. Review.


Recruitment of RNA molecules by connexin RNA-binding motifs: Implication in RNA and DNA transport through microvesicles and exosomes.

Varela-Eirin M, Varela-Vazquez A, Rodríguez-Candela Mateos M, Vila-Sanjurjo A, Fonseca E, Mascareñas JL, Eugenio Vázquez M, Mayan MD.

Biochim Biophys Acta Mol Cell Res. 2017 Apr;1864(4):728-736. doi: 10.1016/j.bbamcr.2017.02.001. Epub 2017 Feb 4. Review.


The presence of highly disruptive 16S rRNA mutations in clinical samples indicates a wider role for mutations of the mitochondrial ribosome in human disease.

Elson JL, Smith PM, Greaves LC, Lightowlers RN, Chrzanowska-Lightowlers ZM, Taylor RW, Vila-Sanjurjo A.

Mitochondrion. 2015 Nov;25:17-27. doi: 10.1016/j.mito.2015.08.004. Epub 2015 Sep 5.


Heterologous inferential analysis (HIA) as a method to understand the role of mitochondrial rRNA mutations in pathogenesis.

Elson JL, Smith PM, Vila-Sanjurjo A.

Methods Mol Biol. 2015;1264:369-83. doi: 10.1007/978-1-4939-2257-4_32.


The role of the mitochondrial ribosome in human disease: searching for mutations in 12S mitochondrial rRNA with high disruptive potential.

Smith PM, Elson JL, Greaves LC, Wortmann SB, Rodenburg RJ, Lightowlers RN, Chrzanowska-Lightowlers ZM, Taylor RW, Vila-Sanjurjo A.

Hum Mol Genet. 2014 Feb 15;23(4):949-67. doi: 10.1093/hmg/ddt490. Epub 2013 Oct 2.


Tertiary interactions between helices h13 and h44 in 16S RNA contribute to the fidelity of translation.

Tran DK, Finley J, Vila-Sanjurjo A, Lale A, Sun Q, O'Connor M.

FEBS J. 2011 Nov;278(22):4405-12. doi: 10.1111/j.1742-4658.2011.08363.x. Epub 2011 Oct 17.


Mutations in the intersubunit bridge regions of 16S rRNA affect decoding and subunit-subunit interactions on the 70S ribosome.

Sun Q, Vila-Sanjurjo A, O'Connor M.

Nucleic Acids Res. 2011 Apr;39(8):3321-30. doi: 10.1093/nar/gkq1253. Epub 2010 Dec 7.


Phylogenetic and multivariate analyses to determine the effects of different tillage and residue management practices on soil bacterial communities.

Ceja-Navarro JA, Rivera-Orduña FN, Patiño-Zúñiga L, Vila-Sanjurjo A, Crossa J, Govaerts B, Dendooven L.

Appl Environ Microbiol. 2010 Jun;76(11):3685-91. doi: 10.1128/AEM.02726-09. Epub 2010 Apr 9.


Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA.

Persaud C, Lu Y, Vila-Sanjurjo A, Campbell JL, Finley J, O'Connor M.

Biochem Biophys Res Commun. 2010 Feb 5;392(2):223-7. doi: 10.1016/j.bbrc.2010.01.021. Epub 2010 Jan 11.


Modification of the Ribosome and the Translational Machinery during Reduced Growth Due to Environmental Stress.

Vila-Sanjurjo A.

EcoSal Plus. 2008 Sep;3(1). doi: 10.1128/ecosalplus.2.5.6.


Modulation of 16S rRNA function by ribosomal protein S12.

Vila-Sanjurjo A, Lu Y, Aragonez JL, Starkweather RE, Sasikumar M, O'Connor M.

Biochim Biophys Acta. 2007 Jul-Aug;1769(7-8):462-71. Epub 2007 Apr 20.


Structural analysis of kasugamycin inhibition of translation.

Schuwirth BS, Day JM, Hau CW, Janssen GR, Dahlberg AE, Cate JH, Vila-Sanjurjo A.

Nat Struct Mol Biol. 2006 Oct;13(10):879-86. Epub 2006 Sep 24.


Structures of the bacterial ribosome at 3.5 A resolution.

Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH.

Science. 2005 Nov 4;310(5749):827-34.


Structural basis for the control of translation initiation during stress.

Vila-Sanjurjo A, Schuwirth BS, Hau CW, Cate JH.

Nat Struct Mol Biol. 2004 Nov;11(11):1054-9. Epub 2004 Oct 24. Erratum in: Nat Struct Mol Biol. 2007 Apr;14(4):351.


X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli.

Vila-Sanjurjo A, Ridgeway WK, Seymaner V, Zhang W, Santoso S, Yu K, Cate JH.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8682-7. Epub 2003 Jul 9.


Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

Vila-Sanjurjo A, Squires CL, Dahlberg AE.

J Mol Biol. 1999 Oct 15;293(1):1-8.


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