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Items: 37

1.

XRN2 promotes EMT and metastasis through regulating maturation of miR-10a.

Zhang H, Lu Y, Chen E, Li X, Lv B, Vikis HG, Liu P.

Oncogene. 2017 Jul 6;36(27):3925-3933. doi: 10.1038/onc.2017.39. Epub 2017 Mar 20.

PMID:
28319071
2.

Glutathione-S-transferase (GST)-fusion based assays for studying protein-protein interactions.

Vikis HG, Guan KL.

Methods Mol Biol. 2015;1278:353-64. doi: 10.1007/978-1-4939-2425-7_22.

PMID:
25859961
3.

The role of neutrophil myeloperoxidase in models of lung tumor development.

Rymaszewski AL, Tate E, Yimbesalu JP, Gelman AE, Jarzembowski JA, Zhang H, Pritchard KA Jr, Vikis HG.

Cancers (Basel). 2014 May 9;6(2):1111-27. doi: 10.3390/cancers6021111.

4.

CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis.

James MA, Vikis HG, Tate E, Rymaszewski AL, You M.

Cancer Res. 2014 Feb 15;74(4):1116-27. doi: 10.1158/0008-5472.CAN-13-1617. Epub 2013 Dec 23.

5.

Mouse models of chemically-induced lung carcinogenesis.

Vikis HG, Rymaszewski AL, Tichelaar JW.

Front Biosci (Elite Ed). 2013 Jun 1;5:939-46. Review.

PMID:
23747909
6.

Strain-specific variation in murine natural killer gene complex contributes to differences in immunosurveillance for urethane-induced lung cancer.

Kreisel D, Gelman AE, Higashikubo R, Lin X, Vikis HG, White JM, Toth KA, Deshpande C, Carreno BM, You M, Taffner SM, Yokoyama WM, Bui JD, Schreiber RD, Krupnick AS.

Cancer Res. 2012 Sep 1;72(17):4311-7. Epub 2012 Jun 29.

7.

Quantitative monitoring of mouse lung tumors by magnetic resonance imaging.

Krupnick AS, Tidwell VK, Engelbach JA, Alli VV, Nehorai A, You M, Vikis HG, Gelman AE, Kreisel D, Garbow JR.

Nat Protoc. 2012 Jan 5;7(1):128-42. doi: 10.1038/nprot.2011.424.

8.

Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis.

Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M.

Mol Carcinog. 2012 Dec;51(12):993-1002. doi: 10.1002/mc.20870. Epub 2011 Oct 17.

9.

Principles for the post-GWAS functional characterization of cancer risk loci.

Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG.

Nat Genet. 2011 Jun;43(6):513-8. doi: 10.1038/ng.840. No abstract available.

10.

Strain-specific susceptibility for pulmonary metastasis of sarcoma 180 cells in inbred mice.

Vikis HG, Jackson EN, Krupnick AS, Franklin A, Gelman AE, Chen Q, Piwnica-Worms D, You M.

Cancer Res. 2010 Jun 15;70(12):4859-67. doi: 10.1158/0008-5472.CAN-09-4177. Epub 2010 May 25.

11.

A second genetic variant on chromosome 15q24-25.1 associates with lung cancer.

Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Spitz M, Amos CI, Anderson MW, You M.

Cancer Res. 2010 Apr 15;70(8):3128-35. doi: 10.1158/0008-5472.CAN-09-3583.

12.

Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.

Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW, You M.

Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):517-24. doi: 10.1158/1055-9965.EPI-09-0791.

13.

Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor.

Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, Franklin A, You M.

Oncogene. 2010 Feb 18;29(7):1041-9. doi: 10.1038/onc.2009.396. Epub 2009 Nov 16.

14.

Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus.

Liu PY, Vikis H, James M, Lu Y, Wang DL, Liu HB, Wen WD, Wang Y, You M.

Cancer Res. 2009 Aug 1;69(15):6290-8. doi: 10.1158/0008-5472.CAN-09-0782. Epub 2009 Jul 21.

15.

Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene.

You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW.

Clin Cancer Res. 2009 Apr 15;15(8):2666-74. doi: 10.1158/1078-0432.CCR-08-2335. Epub 2009 Apr 7.

16.

RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway.

James MA, Lu Y, Liu Y, Vikis HG, You M.

Cancer Res. 2009 Mar 1;69(5):2108-16. doi: 10.1158/0008-5472.CAN-08-3495. Epub 2009 Feb 24.

17.

Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.

Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M.

J Natl Cancer Inst. 2008 Sep 17;100(18):1326-30. doi: 10.1093/jnci/djn268. Epub 2008 Sep 9.

18.
19.

Large-scale in silico mapping of complex quantitative traits in inbred mice.

Liu P, Vikis H, Lu Y, Wang D, You M.

PLoS One. 2007 Jul 25;2(7):e651.

20.

EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.

Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Viswanathan A, Govindan R, Minna J, Anderson MW, You M.

Cancer Res. 2007 May 15;67(10):4665-70.

21.

Fine mapping and candidate gene analyses of pulmonary adenoma resistance 1, a major genetic determinant of mouse lung adenoma resistance.

Wang M, Zhang Z, Zhang Z, Vikis H, Yan Y, Wang Y, You M.

Cancer Res. 2007 Mar 15;67(6):2508-16.

22.

Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1.

Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Minna J, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Liu Y, Viswanathan A, Govindan R, Anderson MW, You M.

Cancer Res. 2007 Jan 1;67(1):93-9.

23.

Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer.

Yan Y, Lu Y, Wang M, Vikis H, Yao R, Wang Y, Lubet RA, You M.

Mol Cancer Res. 2006 Dec;4(12):971-81.

24.

Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.

Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M.

Nat Genet. 2006 Aug;38(8):888-95. Epub 2006 Jul 23.

PMID:
16862160
25.

Measurements of TSC2 GAP activity toward Rheb.

Li Y, Inoki K, Vikis H, Guan KL.

Methods Enzymol. 2006;407:46-54.

PMID:
16757313
26.

Activation of FAK and Src are receptor-proximal events required for netrin signaling.

Li W, Lee J, Vikis HG, Lee SH, Liu G, Aurandt J, Shen TL, Fearon ER, Guan JL, Han M, Rao Y, Hong K, Guan KL.

Nat Neurosci. 2004 Nov;7(11):1213-21. Epub 2004 Oct 17.

27.

Glutathione-S-transferase-fusion based assays for studying protein-protein interactions.

Vikis HG, Guan KL.

Methods Mol Biol. 2004;261:175-86. Review.

PMID:
15064458
28.

Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia.

Wang M, Devereux TR, Vikis HG, McCulloch SD, Holliday W, Anna C, Wang Y, Bebenek K, Kunkel TA, Guan K, You M.

Cancer Res. 2004 Mar 15;64(6):1924-31.

29.

Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice.

Zhang Z, Futamura M, Vikis HG, Wang M, Li J, Wang Y, Guan KL, You M.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12642-7.

30.

Mechanisms of regulating the Raf kinase family.

Chong H, Vikis HG, Guan KL.

Cell Signal. 2003 May;15(5):463-9. Review.

PMID:
12639709
31.

Regulation of the Ras-MAPK pathway at the level of Ras and Raf.

Vikis H, Guan KL.

Genet Eng (N Y). 2002;24:49-66. Review. No abstract available.

PMID:
12416300
32.

The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.

Aurandt J, Vikis HG, Gutkind JS, Ahn N, Guan KL.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12085-90. Epub 2002 Aug 26.

33.

SmgGDS displays differential binding and exchange activity towards different Ras isoforms.

Vikis HG, Stewart S, Guan KL.

Oncogene. 2002 Apr 4;21(15):2425-32.

34.
35.

Wildtype Kras2 can inhibit lung carcinogenesis in mice.

Zhang Z, Wang Y, Vikis HG, Johnson L, Liu G, Li J, Anderson MW, Sills RC, Hong HL, Devereux TR, Jacks T, Guan KL, You M.

Nat Genet. 2001 Sep;29(1):25-33.

PMID:
11528387
36.

The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner.

Vikis HG, Li W, He Z, Guan KL.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12457-62.

37.

Regulation of STAT3 by direct binding to the Rac1 GTPase.

Simon AR, Vikis HG, Stewart S, Fanburg BL, Cochran BH, Guan KL.

Science. 2000 Oct 6;290(5489):144-7.

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