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Items: 1 to 50 of 55

1.

A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9.

Cui L, Vigouroux A, Rousset F, Varet H, Khanna V, Bikard D.

Nat Commun. 2018 May 15;9(1):1912. doi: 10.1038/s41467-018-04209-5.

2.

Further delineation of the MECP2 duplication syndrome phenotype in 59 French male patients, with a particular focus on morphological and neurological features.

Miguet M, Faivre L, Amiel J, Nizon M, Touraine R, Prieur F, Pasquier L, Lefebvre M, Thevenon J, Dubourg C, Julia S, Sarret C, Remerand G, Francannet C, Laffargue F, Boespflug-Tanguy O, David A, Isidor B, Vigneron J, Leheup B, Lambert L, Philippe C, Béri-Dexheimer M, Cuisset JM, Andrieux J, Plessis G, Toutain A, Guibaud L, Cormier-Daire V, Rio M, Bonnefont JP, Echenne B, Journel H, Burglen L, Chantot-Bastaraud S, Bienvenu T, Baumann C, Perrin L, Drunat S, Jouk PS, Dieterich K, Devillard F, Lacombe D, Philip N, Sigaudy S, Moncla A, Missirian C, Badens C, Perreton N, Thauvin-Robinet C, AChro-Puce R, Pedespan JM, Rooryck C, Goizet C, Vincent-Delorme C, Duban-Bedu B, Bahi-Buisson N, Afenjar A, Maincent K, Héron D, Alessandri JL, Martin-Coignard D, Lesca G, Rossi M, Raynaud M, Callier P, Mosca-Boidron AL, Marle N, Coutton C, Satre V, Caignec CL, Malan V, Romana S, Keren B, Tabet AC, Kremer V, Scheidecker S, Vigouroux A, Lackmy-Port-Lis M, Sanlaville D, Till M, Carneiro M, Gilbert-Dussardier B, Willems M, Van Esch H, Portes VD, El Chehadeh S.

J Med Genet. 2018 Jun;55(6):359-371. doi: 10.1136/jmedgenet-2017-104956. Epub 2018 Apr 4.

PMID:
29618507
3.

The plant defense signal galactinol is specifically used as a nutrient by the bacterial pathogen Agrobacterium fabrum.

Meyer T, Vigouroux A, Aumont-Nicaise M, Comte G, Vial L, Lavire C, Moréra S.

J Biol Chem. 2018 May 25;293(21):7930-7941. doi: 10.1074/jbc.RA118.001856. Epub 2018 Mar 30.

PMID:
29602905
4.

Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes.

Vigouroux A, Oldewurtel E, Cui L, Bikard D, van Teeffelen S.

Mol Syst Biol. 2018 Mar 8;14(3):e7899. doi: 10.15252/msb.20177899.

5.

Regulation of Hydroxycinnamic Acid Degradation Drives Agrobacterium fabrum Lifestyles.

Meyer T, Renoud S, Vigouroux A, Miomandre A, Gaillard V, Kerzaon I, Prigent-Combaret C, Comte G, Moréra S, Vial L, Lavire C.

Mol Plant Microbe Interact. 2018 Aug;31(8):814-822. doi: 10.1094/MPMI-10-17-0236-R. Epub 2018 Jun 22.

PMID:
29460677
6.

Structural basis for high specificity of octopine binding in the plant pathogen Agrobacterium tumefaciens.

Vigouroux A, El Sahili A, Lang J, Aumont-Nicaise M, Dessaux Y, Faure D, Moréra S.

Sci Rep. 2017 Dec 21;7(1):18033. doi: 10.1038/s41598-017-18243-8.

7.

4q25 microdeletion encompassing PITX2: A patient presenting with tetralogy of Fallot and dental anomalies without ocular features.

Vande Perre P, Zazo Seco C, Patat O, Bouneau L, Vigouroux A, Bourgeois D, El Hout S, Chassaing N, Calvas P.

Eur J Med Genet. 2018 Feb;61(2):72-78. doi: 10.1016/j.ejmg.2017.10.018. Epub 2017 Oct 31.

PMID:
29100920
8.

Gouvernance des politiques publiques favorables à la santé : l’expérience menée en Poitou-Charentes, France.

Le Vigouroux A, Marcheix C, Autès E.

Glob Health Promot. 2017 Aug 1:1757975917701689. doi: 10.1177/1757975917701689. [Epub ahead of print] French. No abstract available.

PMID:
28805501
9.

The ALDH21 gene found in lower plants and some vascular plants codes for a NADP+ -dependent succinic semialdehyde dehydrogenase.

Kopečná M, Vigouroux A, Vilím J, Končitíková R, Briozzo P, Hájková E, Jašková L, von Schwartzenberg K, Šebela M, Moréra S, Kopečný D.

Plant J. 2017 Oct;92(2):229-243. doi: 10.1111/tpj.13648. Epub 2017 Sep 2.

PMID:
28749584
10.

Fever, arthritis, and cutaneous lesions.

Bachmeyer C, Vigouroux A, Moguelet P.

Eur J Intern Med. 2017 Dec;46:e3-e4. doi: 10.1016/j.ejim.2017.04.023. Epub 2017 May 6. No abstract available.

PMID:
28483370
11.

Fitness costs restrict niche expansion by generalist niche-constructing pathogens.

Lang J, Vigouroux A, El Sahili A, Kwasiborski A, Aumont-Nicaise M, Dessaux Y, Shykoff JA, Moréra S, Faure D.

ISME J. 2017 Feb;11(2):374-385. doi: 10.1038/ismej.2016.137. Epub 2016 Nov 1.

12.

Structural Basis for High Specificity of Amadori Compound and Mannopine Opine Binding in Bacterial Pathogens.

Marty L, Vigouroux A, Aumont-Nicaise M, Dessaux Y, Faure D, Moréra S.

J Biol Chem. 2016 Oct 21;291(43):22638-22649. Epub 2016 Sep 8.

13.

Association of biomarkers with health-related quality of life and history of stressors in myalgic encephalomyelitis/chronic fatigue syndrome patients.

Fenouillet E, Vigouroux A, Steinberg JG, Chagvardieff A, Retornaz F, Guieu R, Jammes Y.

J Transl Med. 2016 Aug 31;14:251. doi: 10.1186/s12967-016-1010-x.

14.

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.

Cerezo M, Lehraiki A, Millet A, Rouaud F, Plaisant M, Jaune E, Botton T, Ronco C, Abbe P, Amdouni H, Passeron T, Hofman V, Mograbi B, Dabert-Gay AS, Debayle D, Alcor D, Rabhi N, Annicotte JS, Héliot L, Gonzalez-Pisfil M, Robert C, Moréra S, Vigouroux A, Gual P, Ali MMU, Bertolotto C, Hofman P, Ballotti R, Benhida R, Rocchi S.

Cancer Cell. 2016 Jul 11;30(1):183. doi: 10.1016/j.ccell.2016.06.007. Epub 2016 Jul 11. No abstract available.

15.

Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA.

Redrejo-Rodríguez M, Vigouroux A, Mursalimov A, Grin I, Alili D, Koshenov Z, Akishev Z, Maksimenko A, Bissenbaev AK, Matkarimov BT, Saparbaev M, Ishchenko AA, Moréra S.

Biochimie. 2016 Sep-Oct;128-129:20-33. doi: 10.1016/j.biochi.2016.06.011. Epub 2016 Jun 22.

16.

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.

Cerezo M, Lehraiki A, Millet A, Rouaud F, Plaisant M, Jaune E, Botton T, Ronco C, Abbe P, Amdouni H, Passeron T, Hofman V, Mograbi B, Dabert-Gay AS, Debayle D, Alcor D, Rabhi N, Annicotte JS, Héliot L, Gonzalez-Pisfil M, Robert C, Moréra S, Vigouroux A, Gual P, Ali MMU, Bertolotto C, Hofman P, Ballotti R, Benhida R, Rocchi S.

Cancer Cell. 2016 Jun 13;29(6):805-819. doi: 10.1016/j.ccell.2016.04.013. Epub 2016 May 26. Erratum in: Cancer Cell. 2016 Jul 11;30(1):183.

17.

Functional and structural characterization of two Bacillus megaterium nitroreductases biotransforming the herbicide mesotrione.

Carles L, Besse-Hoggan P, Joly M, Vigouroux A, Moréra S, Batisson I.

Biochem J. 2016 May 15;473(10):1443-53. doi: 10.1042/BJ20151366. Epub 2016 Mar 22.

PMID:
27005432
18.

Kinetic and structural investigation of the cytokinin oxidase/dehydrogenase active site.

Kopečný D, Končitíková R, Popelka H, Briozzo P, Vigouroux A, Kopečná M, Zalabák D, Šebela M, Skopalová J, Frébort I, Moréra S.

FEBS J. 2016 Jan;283(2):361-77. doi: 10.1111/febs.13581. Epub 2015 Nov 26.

19.

A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens.

El Sahili A, Li SZ, Lang J, Virus C, Planamente S, Ahmar M, Guimaraes BG, Aumont-Nicaise M, Vigouroux A, Soulère L, Reader J, Queneau Y, Faure D, Moréra S.

PLoS Pathog. 2015 Aug 5;11(8):e1005071. doi: 10.1371/journal.ppat.1005071. eCollection 2015 Aug.

20.

Role and structural characterization of plant aldehyde dehydrogenases from family 2 and family 7.

Končitíková R, Vigouroux A, Kopečná M, Andree T, Bartoš J, Šebela M, Moréra S, Kopečný D.

Biochem J. 2015 May 15;468(1):109-23. doi: 10.1042/BJ20150009.

PMID:
25734422
21.

Agrobacterium uses a unique ligand-binding mode for trapping opines and acquiring a competitive advantage in the niche construction on plant host.

Lang J, Vigouroux A, Planamente S, El Sahili A, Blin P, Aumont-Nicaise M, Dessaux Y, Moréra S, Faure D.

PLoS Pathog. 2014 Oct 9;10(10):e1004444. doi: 10.1371/journal.ppat.1004444. eCollection 2014 Oct.

22.

Constitutional chromoanasynthesis: description of a rare chromosomal event in a patient.

Plaisancié J, Kleinfinger P, Cances C, Bazin A, Julia S, Trost D, Lohmann L, Vigouroux A.

Eur J Med Genet. 2014 Oct;57(10):567-70. doi: 10.1016/j.ejmg.2014.07.004. Epub 2014 Aug 13.

PMID:
25128687
23.

New candidate loci identified by array-CGH in a cohort of 100 children presenting with syndromic obesity.

Vuillaume ML, Naudion S, Banneau G, Diene G, Cartault A, Cailley D, Bouron J, Toutain J, Bourrouillou G, Vigouroux A, Bouneau L, Nacka F, Kieffer I, Arveiler B, Knoll-Gellida A, Babin PJ, Bieth E, Jouret B, Julia S, Sarda P, Geneviève D, Faivre L, Lacombe D, Barat P, Tauber M, Delrue MA, Rooryck C.

Am J Med Genet A. 2014 Aug;164A(8):1965-75. doi: 10.1002/ajmg.a.36587. Epub 2014 Apr 29.

PMID:
24782328
24.

Distal 10q monosomy: new evidence for a neurobehavioral condition?

Plaisancié J, Bouneau L, Cances C, Garnier C, Benesteau J, Leonard S, Bourrouillou G, Calvas P, Vigouroux A, Julia S, Bieth E.

Eur J Med Genet. 2014 Jan;57(1):47-53. doi: 10.1016/j.ejmg.2013.11.002. Epub 2013 Nov 23.

PMID:
24275544
25.

Structure and function of nucleoside hydrolases from Physcomitrella patens and maize catalyzing the hydrolysis of purine, pyrimidine, and cytokinin ribosides.

Kopecná M, Blaschke H, Kopecny D, Vigouroux A, Koncitíková R, Novák O, Kotland O, Strnad M, Moréra S, von Schwartzenberg K.

Plant Physiol. 2013 Dec;163(4):1568-83. doi: 10.1104/pp.113.228775. Epub 2013 Oct 29.

26.

Molecular findings and clinical data in a cohort of 150 patients with anophthalmia/microphthalmia.

Chassaing N, Causse A, Vigouroux A, Delahaye A, Alessandri JL, Boespflug-Tanguy O, Boute-Benejean O, Dollfus H, Duban-Bedu B, Gilbert-Dussardier B, Giuliano F, Gonzales M, Holder-Espinasse M, Isidor B, Jacquemont ML, Lacombe D, Martin-Coignard D, Mathieu-Dramard M, Odent S, Picone O, Pinson L, Quelin C, Sigaudy S, Toutain A, Thauvin-Robinet C, Kaplan J, Calvas P.

Clin Genet. 2014 Oct;86(4):326-34. doi: 10.1111/cge.12275. Epub 2013 Oct 7.

PMID:
24033328
27.

Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases.

Mazouzi A, Vigouroux A, Aikeshev B, Brooks PJ, Saparbaev MK, Morera S, Ishchenko AA.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3071-80. doi: 10.1073/pnas.1305281110. Epub 2013 Jul 29.

28.

A metagenomic study highlights phylogenetic proximity of quorum-quenching and xenobiotic-degrading amidases of the AS-family.

Tannières M, Beury-Cirou A, Vigouroux A, Mondy S, Pellissier F, Dessaux Y, Faure D.

PLoS One. 2013 Jun 7;8(6):e65473. doi: 10.1371/journal.pone.0065473. Print 2013.

29.

Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain.

Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P.

Hum Mutat. 2013 Jun;34(6):801-11. doi: 10.1002/humu.22313. Epub 2013 Apr 12.

30.

Plant ALDH10 family: identifying critical residues for substrate specificity and trapping a thiohemiacetal intermediate.

Kopečny D, Končitíková R, Tylichová M, Vigouroux A, Moskalíková H, Soural M, Šebela M, Moréra S.

J Biol Chem. 2013 Mar 29;288(13):9491-507. doi: 10.1074/jbc.M112.443952. Epub 2013 Feb 13.

31.

Structural basis for selective GABA binding in bacterial pathogens.

Planamente S, Mondy S, Hommais F, Vigouroux A, Moréra S, Faure D.

Mol Microbiol. 2012 Dec;86(5):1085-99. doi: 10.1111/mmi.12043. Epub 2012 Oct 9.

32.

[Continuity of hospital care and foreign doctors: regularization of a system and its limitations in France].

Le Vigouroux A.

Glob Health Promot. 2012 Sep;19(3):74-7. doi: 10.1177/1757975912453862. French. No abstract available.

PMID:
24802790
33.

Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.

Moréra S, Grin I, Vigouroux A, Couvé S, Henriot V, Saparbaev M, Ishchenko AA.

Nucleic Acids Res. 2012 Oct;40(19):9917-26. doi: 10.1093/nar/gks714. Epub 2012 Jul 30.

34.

14q12 and severe Rett-like phenotypes: new clinical insights and physical mapping of FOXG1-regulatory elements.

Allou L, Lambert L, Amsallem D, Bieth E, Edery P, Destrée A, Rivier F, Amor D, Thompson E, Nicholl J, Harbord M, Nemos C, Saunier A, Moustaïne A, Vigouroux A, Jonveaux P, Philippe C.

Eur J Hum Genet. 2012 Dec;20(12):1216-23. doi: 10.1038/ejhg.2012.127. Epub 2012 Jun 27.

35.

OTX2 mutations contribute to the otocephaly-dysgnathia complex.

Chassaing N, Sorrentino S, Davis EE, Martin-Coignard D, Iacovelli A, Paznekas W, Webb BD, Faye-Petersen O, Encha-Razavi F, Lequeux L, Vigouroux A, Yesilyurt A, Boyadjiev SA, Kayserili H, Loget P, Carles D, Sergi C, Puvabanditsin S, Chen CP, Etchevers HC, Katsanis N, Mercer CL, Calvas P, Jabs EW.

J Med Genet. 2012 Jun;49(6):373-9. doi: 10.1136/jmedgenet-2012-100892. Epub 2012 May 10.

PMID:
22577225
36.

Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.

Gaude H, Aznar N, Delay A, Bres A, Buchet-Poyau K, Caillat C, Vigouroux A, Rogon C, Woods A, Vanacker JM, Höhfeld J, Perret C, Meyer P, Billaud M, Forcet C.

Oncogene. 2012 Mar 22;31(12):1582-91. doi: 10.1038/onc.2011.342. Epub 2011 Aug 22.

PMID:
21860411
37.

A potential fortuitous binding of inhibitors of an inverting family GH9 β-glycosidase derived from isofagomine.

Moréra S, Vigouroux A, Stubbs KA.

Org Biomol Chem. 2011 Sep 7;9(17):5945-7. doi: 10.1039/c1ob05766a. Epub 2011 Jul 25.

PMID:
21785782
38.

A 10 Mb duplication in chromosome band 5q31.3-5q33.1 associated with late-onset lipodystrophy, ichthyosis, epilepsy and glomerulonephritis.

Faguer S, De Sandre-Giovannoli A, Hemery M, Lévy N, Lamant L, Arveiler B, Rooryck C, Prouheze C, Vigouroux A, Chauveau D, Calvas P, Chassaing N.

Eur J Med Genet. 2011 May-Jun;54(3):310-3. doi: 10.1016/j.ejmg.2011.01.005. Epub 2011 Jan 27.

PMID:
21276880
39.

Mutations in the LHX2 gene are not a frequent cause of micro/anophthalmia.

Desmaison A, Vigouroux A, Rieubland C, Peres C, Calvas P, Chassaing N.

Mol Vis. 2010 Dec 18;16:2847-9.

40.

The Pih1-Tah1 cochaperone complex inhibits Hsp90 molecular chaperone ATPase activity.

Eckert K, Saliou JM, Monlezun L, Vigouroux A, Atmane N, Caillat C, Quevillon-Chéruel S, Madiona K, Nicaise M, Lazereg S, Van Dorsselaer A, Sanglier-Cianférani S, Meyer P, Moréra S.

J Biol Chem. 2010 Oct 8;285(41):31304-12. doi: 10.1074/jbc.M110.138263. Epub 2010 Jul 27.

41.

Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export.

Bechet E, Gruszczyk J, Terreux R, Gueguen-Chaignon V, Vigouroux A, Obadia B, Cozzone AJ, Nessler S, Grangeasse C.

Mol Microbiol. 2010 Sep;77(5):1315-25. doi: 10.1111/j.1365-2958.2010.07291.x.

42.

A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.

Planamente S, Vigouroux A, Mondy S, Nicaise M, Faure D, Moréra S.

J Biol Chem. 2010 Sep 24;285(39):30294-303. doi: 10.1074/jbc.M110.140715. Epub 2010 Jul 14.

43.

Novel B3GALTL mutation in Peters-plus Syndrome.

Dassie-Ajdid J, Causse A, Poidvin A, Granier M, Kaplan J, Burglen L, Doummar D, Teisseire P, Vigouroux A, Malecaze F, Calvas P, Chassaing N.

Clin Genet. 2009 Nov;76(5):490-2. doi: 10.1111/j.1399-0004.2009.01253.x. Epub 2009 Sep 30. No abstract available.

PMID:
19796186
44.

Crystal structures of A. acidocaldarius endoglucanase Cel9A in complex with cello-oligosaccharides: strong -1 and -2 subsites mimic cellobiohydrolase activity.

Eckert K, Vigouroux A, Lo Leggio L, Moréra S.

J Mol Biol. 2009 Nov 20;394(1):61-70. doi: 10.1016/j.jmb.2009.08.060. Epub 2009 Aug 31.

PMID:
19729024
45.

[Evolution of genetic testing techniques].

Vigouroux A, Chassaing N.

Arch Pediatr. 2009 Jun;16(6):915-7. doi: 10.1016/S0929-693X(09)74202-2. French. No abstract available.

PMID:
19541220
46.

The picobirnavirus crystal structure provides functional insights into virion assembly and cell entry.

Duquerroy S, Da Costa B, Henry C, Vigouroux A, Libersou S, Lepault J, Navaza J, Delmas B, Rey FA.

EMBO J. 2009 Jun 3;28(11):1655-65. doi: 10.1038/emboj.2009.109. Epub 2009 Apr 30.

47.

Mutations in the newly identified RAX regulatory sequence are not a frequent cause of micro/anophthalmia.

Chassaing N, Vigouroux A, Calvas P.

Genet Test Mol Biomarkers. 2009 Jun;13(3):289-90. doi: 10.1089/gtmb.2008.0143.

PMID:
19397404
48.

Phenotypic spectrum of STRA6 mutations: from Matthew-Wood syndrome to non-lethal anophthalmia.

Chassaing N, Golzio C, Odent S, Lequeux L, Vigouroux A, Martinovic-Bouriel J, Tiziano FD, Masini L, Piro F, Maragliano G, Delezoide AL, Attié-Bitach T, Manouvrier-Hanu S, Etchevers HC, Calvas P.

Hum Mutat. 2009 May;30(5):E673-81. doi: 10.1002/humu.21023.

PMID:
19309693
49.

Confirmation of RAX gene involvement in human anophthalmia.

Lequeux L, Rio M, Vigouroux A, Titeux M, Etchevers H, Malecaze F, Chassaing N, Calvas P.

Clin Genet. 2008 Oct;74(4):392-5. doi: 10.1111/j.1399-0004.2008.01078.x. Epub 2008 Sep 9.

50.

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