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Items: 1 to 50 of 284

1.

Kinetic Modeling of Hyperpolarized Carbon-13 Pyruvate Metabolism in the Human Brain.

Mammoli D, Gordon J, Autry A, Larson PEZ, Li Y, Chen HY, Chung B, Shin P, Van Criekinge M, Carvajal L, Slater JB, Bok R, Crane J, Xu D, Chang S, Vigneron DB.

IEEE Trans Med Imaging. 2019 Jul 2. doi: 10.1109/TMI.2019.2926437. [Epub ahead of print]

PMID:
31283497
2.

Zero-field nuclear magnetic resonance of chemically exchanging systems.

Barskiy DA, Tayler MCD, Marco-Rius I, Kurhanewicz J, Vigneron DB, Cikrikci S, Aydogdu A, Reh M, Pravdivtsev AN, Hövener JB, Blanchard JW, Wu T, Budker D, Pines A.

Nat Commun. 2019 Jul 5;10(1):3002. doi: 10.1038/s41467-019-10787-9.

3.

Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.

Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR.

Magn Reson Med. 2019 Sep;82(3):959-972. doi: 10.1002/mrm.27780. Epub 2019 May 3.

PMID:
31050049
4.

Comparison between 8- and 32-channel phased-array receive coils for in vivo hyperpolarized 13 C imaging of the human brain.

Autry AW, Gordon JW, Carvajal L, Mareyam A, Chen HY, Park I, Mammoli D, Vareth M, Chang SM, Wald LL, Xu D, Vigneron DB, Nelson SJ, Li Y.

Magn Reson Med. 2019 Aug;82(2):833-841. doi: 10.1002/mrm.27743. Epub 2019 Mar 29.

5.

Methodological consensus on clinical proton MRS of the brain: Review and recommendations.

Wilson M, Andronesi O, Barker PB, Bartha R, Bizzi A, Bolan PJ, Brindle KM, Choi IY, Cudalbu C, Dydak U, Emir UE, Gonzalez RG, Gruber S, Gruetter R, Gupta RK, Heerschap A, Henning A, Hetherington HP, Huppi PS, Hurd RE, Kantarci K, Kauppinen RA, Klomp DWJ, Kreis R, Kruiskamp MJ, Leach MO, Lin AP, Luijten PR, Marjańska M, Maudsley AA, Meyerhoff DJ, Mountford CE, Mullins PG, Murdoch JB, Nelson SJ, Noeske R, Öz G, Pan JW, Peet AC, Poptani H, Posse S, Ratai EM, Salibi N, Scheenen TWJ, Smith ICP, Soher BJ, Tkáč I, Vigneron DB, Howe FA.

Magn Reson Med. 2019 Aug;82(2):527-550. doi: 10.1002/mrm.27742. Epub 2019 Mar 28. Review.

PMID:
30919510
6.

Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies.

Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW.

J Magn Reson. 2019 Apr;301:73-79. doi: 10.1016/j.jmr.2019.01.015. Epub 2019 Feb 1.

PMID:
30851668
7.

Hyperpolarized 13C MRI: State of the Art and Future Directions.

Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB.

Radiology. 2019 May;291(2):273-284. doi: 10.1148/radiol.2019182391. Epub 2019 Mar 5.

PMID:
30835184
8.

The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized 13C MRSI.

Bok R, Lee J, Sriram R, Keshari K, Sukumar S, Daneshmandi S, Korenchan DE, Flavell RR, Vigneron DB, Kurhanewicz J, Seth P.

Cancers (Basel). 2019 Feb 22;11(2). pii: E257. doi: 10.3390/cancers11020257.

9.

Effects of excitation angle strategy on quantitative analysis of hyperpolarized pyruvate.

Walker CM, Fuentes D, Larson PEZ, Kundra V, Vigneron DB, Bankson JA.

Magn Reson Med. 2019 Jun;81(6):3754-3762. doi: 10.1002/mrm.27687. Epub 2019 Feb 22.

PMID:
30793791
10.

Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13 C imaging.

Chen HY, Gordon JW, Bok RA, Cao P, von Morze C, van Criekinge M, Milshteyn E, Carvajal L, Hurd RE, Kurhanewicz J, Vigneron DB, Larson PEZ.

NMR Biomed. 2019 Mar;32(3):e4052. doi: 10.1002/nbm.4052. Epub 2019 Jan 21.

PMID:
30664305
11.

Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology.

Kurhanewicz J, Vigneron DB, Ardenkjaer-Larsen JH, Bankson JA, Brindle K, Cunningham CH, Gallagher FA, Keshari KR, Kjaer A, Laustsen C, Mankoff DA, Merritt ME, Nelson SJ, Pauly JM, Lee P, Ronen S, Tyler DJ, Rajan SS, Spielman DM, Wald L, Zhang X, Malloy CR, Rizi R.

Neoplasia. 2019 Jan;21(1):1-16. doi: 10.1016/j.neo.2018.09.006. Epub 2018 Nov 23. Review.

12.

Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.

Gordon JW, Chen HY, Autry A, Park I, Van Criekinge M, Mammoli D, Milshteyn E, Bok R, Xu D, Li Y, Aggarwal R, Chang S, Slater JB, Ferrone M, Nelson S, Kurhanewicz J, Larson PEZ, Vigneron DB.

Magn Reson Med. 2019 Apr;81(4):2702-2709. doi: 10.1002/mrm.27549. Epub 2018 Oct 30.

PMID:
30375043
13.

A regional bolus tracking and real-time B1 calibration method for hyperpolarized 13 C MRI.

Tang S, Milshteyn E, Reed G, Gordon J, Bok R, Zhu X, Zhu Z, Vigneron DB, Larson PEZ.

Magn Reson Med. 2019 Feb;81(2):839-851. doi: 10.1002/mrm.27391. Epub 2018 Sep 18.

PMID:
30277268
14.

Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients.

Larson PEZ, Chen HY, Gordon JW, Korn N, Maidens J, Arcak M, Tang S, Criekinge M, Carvajal L, Mammoli D, Bok R, Aggarwal R, Ferrone M, Slater JB, Nelson SJ, Kurhanewicz J, Vigneron DB.

NMR Biomed. 2018 Nov;31(11):e3997. doi: 10.1002/nbm.3997. Epub 2018 Sep 19.

PMID:
30230646
15.

Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized 13C Pyruvate MRI.

Sriram R, Gordon J, Baligand C, Ahamed F, Delos Santos J, Qin H, Bok RA, Vigneron DB, Kurhanewicz J, Larson PEZ, Wang ZJ.

Cancers (Basel). 2018 Sep 5;10(9). pii: E313. doi: 10.3390/cancers10090313.

16.

Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging.

Autry AW, Hashizume R, James CD, Larson PEZ, Vigneron DB, Park I.

Contrast Media Mol Imaging. 2018 Jul 30;2018:3215658. doi: 10.1155/2018/3215658. eCollection 2018.

17.

Assessing high-intensity focused ultrasound treatment of prostate cancer with hyperpolarized 13 C dual-agent imaging of metabolism and perfusion.

Lee JE, Diederich CJ, Bok R, Sriram R, Santos RD, Noworolski SM, Salgaonkar VA, Adams MS, Vigneron DB, Kurhanewicz J.

NMR Biomed. 2019 Oct;32(10):e3962. doi: 10.1002/nbm.3962. Epub 2018 Jul 18.

PMID:
30022550
18.

Spatio-Temporally Constrained Reconstruction for Hyperpolarized Carbon-13 MRI Using Kinetic Models.

Maidens J, Gordon JW, Chen HY, Park I, Van Criekinge M, Milshteyn E, Bok R, Aggarwal R, Ferrone M, Slater JB, Kurhanewicz J, Vigneron DB, Arcak M, Larson PEZ.

IEEE Trans Med Imaging. 2018 Dec;37(12):2603-2612. doi: 10.1109/TMI.2018.2844246. Epub 2018 Jun 5.

PMID:
29994332
19.

Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI.

Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR.

Chem Commun (Camb). 2018 May 17;54(41):5233-5236. doi: 10.1039/c8cc02246a.

20.

Technique development of 3D dynamic CS-EPSI for hyperpolarized 13 C pyruvate MR molecular imaging of human prostate cancer.

Chen HY, Larson PEZ, Gordon JW, Bok RA, Ferrone M, van Criekinge M, Carvajal L, Cao P, Pauly JM, Kerr AB, Park I, Slater JB, Nelson SJ, Munster PN, Aggarwal R, Kurhanewicz J, Vigneron DB.

Magn Reson Med. 2018 Nov;80(5):2062-2072. doi: 10.1002/mrm.27179. Epub 2018 Mar 25.

PMID:
29575178
21.

Using a local low rank plus sparse reconstruction to accelerate dynamic hyperpolarized 13C imaging using the bSSFP sequence.

Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Larson PEZ, Vigneron DB.

J Magn Reson. 2018 May;290:46-59. doi: 10.1016/j.jmr.2018.03.006. Epub 2018 Mar 11.

22.

In vivo hyperpolarization transfer in a clinical MRI scanner.

von Morze C, Reed GD, Larson PE, Mammoli D, Chen AP, Tropp J, Van Criekinge M, Ohliger MA, Kurhanewicz J, Vigneron DB, Merritt ME.

Magn Reson Med. 2018 Aug;80(2):480-487. doi: 10.1002/mrm.27154. Epub 2018 Feb 27.

23.

3D hyperpolarized C-13 EPI with calibrationless parallel imaging.

Gordon JW, Hansen RB, Shin PJ, Feng Y, Vigneron DB, Larson PEZ.

J Magn Reson. 2018 Apr;289:92-99. doi: 10.1016/j.jmr.2018.02.011. Epub 2018 Feb 13.

24.

High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-13 C]pyruvate and [1-13 C]lactate with spectral suppression of alanine and pyruvate-hydrate.

Milshteyn E, von Morze C, Gordon JW, Zhu Z, Larson PEZ, Vigneron DB.

Magn Reson Med. 2018 Sep;80(3):1048-1060. doi: 10.1002/mrm.27104. Epub 2018 Feb 16. No abstract available.

25.

Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo.

Morze CV, Allu PKR, Chang GY, Marco-Rius I, Milshteyn E, Wang ZJ, Ohliger MA, Gleason CE, Kurhanewicz J, Vigneron DB, Pearce D.

Sci Rep. 2018 Feb 1;8(1):2088. doi: 10.1038/s41598-018-20264-w.

26.

Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies.

Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ.

Magn Reson Med. 2018 Sep;80(3):864-873. doi: 10.1002/mrm.27077. Epub 2018 Jan 10. No abstract available.

27.

Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate.

von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ.

Magn Reson Med. 2018 Apr;79(4):1862-1869. doi: 10.1002/mrm.27054. Epub 2018 Jan 3.

28.

Sensitivity enhancement for detection of hyperpolarized 13 C MRI probes with 1 H spin coupling introduced by enzymatic transformation in vivo.

von Morze C, Tropp J, Chen AP, Marco-Rius I, Van Criekinge M, Skloss TW, Mammoli D, Kurhanewicz J, Vigneron DB, Ohliger MA, Merritt ME.

Magn Reson Med. 2018 Jul;80(1):36-41. doi: 10.1002/mrm.27000. Epub 2017 Nov 28.

29.

Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Androgen Ablation Therapy in Prostate Cancer.

Aggarwal R, Vigneron DB, Kurhanewicz J.

Eur Urol. 2017 Dec;72(6):1028-1029. doi: 10.1016/j.eururo.2017.07.022. Epub 2017 Jul 29. No abstract available.

30.

Cancer recurrence monitoring using hyperpolarized [1-13C]pyruvate metabolic imaging in murine breast cancer model.

Shin PJ, Zhu Z, Camarda R, Bok RA, Zhou AY, Kurhanewicz J, Goga A, Vigneron DB.

Magn Reson Imaging. 2017 Nov;43:105-109. doi: 10.1016/j.mri.2017.07.014. Epub 2017 Jul 15.

31.

Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion.

Chen HY, Larson PEZ, Bok RA, von Morze C, Sriram R, Delos Santos R, Delos Santos J, Gordon JW, Bahrami N, Ferrone M, Kurhanewicz J, Vigneron DB.

Cancer Res. 2017 Jun 15;77(12):3207-3216. doi: 10.1158/0008-5472.CAN-16-2083. Epub 2017 Apr 20.

32.

Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver.

Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA.

J Magn Reson Imaging. 2018 Jan;47(1):141-151. doi: 10.1002/jmri.25721. Epub 2017 Apr 17.

33.

Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging.

Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR.

Analyst. 2017 May 2;142(9):1429-1433. doi: 10.1039/c7an00076f.

34.

Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques.

Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Zhu Z, Chen HY, Bok R, Goga A, Kurhanewicz J, Larson PE, Vigneron DB.

Magn Reson Imaging. 2017 May;38:152-162. doi: 10.1016/j.mri.2017.01.003. Epub 2017 Jan 7.

35.

Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone.

Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M.

Magn Reson Med. 2017 Jan;77(1):65-73. doi: 10.1002/mrm.26525. Epub 2016 Nov 17.

36.

Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses.

Shang H, Sukumar S, von Morze C, Bok RA, Marco-Rius I, Kerr A, Reed GD, Milshteyn E, Ohliger MA, Kurhanewicz J, Larson PEZ, Pauly JM, Vigneron DB.

Magn Reson Med. 2017 Sep;78(3):963-975. doi: 10.1002/mrm.26480. Epub 2016 Oct 21.

37.

Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects.

Gordon JW, Milshteyn E, Marco-Rius I, Ohliger M, Vigneron DB, Larson PEZ.

Magn Reson Med. 2017 Sep;78(3):1087-1092. doi: 10.1002/mrm.26482. Epub 2016 Oct 13.

38.

Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry.

Reed GD, von Morze C, Verkman AS, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB.

Tomography. 2016 Jun;2(2):125-135.

39.

Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR.

Koelsch BL, Sriram R, Keshari KR, Leon Swisher C, Van Criekinge M, Sukumar S, Vigneron DB, Wang ZJ, Larson PEZ, Kurhanewicz J.

J Magn Reson. 2016 Sep;270:115-123. doi: 10.1016/j.jmr.2016.07.002. Epub 2016 Jul 9.

40.

Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing.

Cao P, Shin PJ, Park I, Najac C, Marco-Rius I, Vigneron DB, Nelson SJ, Ronen SM, Larson PE.

Magn Reson Med. 2016 Aug;76(2):369-79. doi: 10.1002/mrm.26272. Epub 2016 May 26.

41.

Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver.

von Morze C, Chang GY, Larson PE, Shang H, Allu PK, Bok RA, Crane JC, Olson MP, Tan CT, Marco-Rius I, Nelson SJ, Kurhanewicz J, Pearce D, Vigneron DB.

Magn Reson Med. 2017 Apr;77(4):1429-1437. doi: 10.1002/mrm.26245. Epub 2016 Apr 21.

42.

Multiband spectral-spatial RF excitation for hyperpolarized [2-13 C]dihydroxyacetone 13 C-MR metabolism studies.

Marco-Rius I, Cao P, von Morze C, Merritt M, Moreno KX, Chang GY, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB.

Magn Reson Med. 2017 Apr;77(4):1419-1428. doi: 10.1002/mrm.26226. Epub 2016 Mar 28.

43.

Development of a symmetric echo planar imaging framework for clinical translation of rapid dynamic hyperpolarized 13 C imaging.

Gordon JW, Vigneron DB, Larson PE.

Magn Reson Med. 2017 Feb;77(2):826-832. doi: 10.1002/mrm.26123. Epub 2016 Feb 21.

44.

Investigating tumor perfusion by hyperpolarized 13 C MRI with comparison to conventional gadolinium contrast-enhanced MRI and pathology in orthotopic human GBM xenografts.

Park I, von Morze C, Lupo JM, Ardenkjaer-Larsen JH, Kadambi A, Vigneron DB, Nelson SJ.

Magn Reson Med. 2017 Feb;77(2):841-847. doi: 10.1002/mrm.26155. Epub 2016 Feb 19.

45.

Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging.

Korenchan DE, Flavell RR, Baligand C, Sriram R, Neumann K, Sukumar S, VanBrocklin H, Vigneron DB, Wilson DM, Kurhanewicz J.

Chem Commun (Camb). 2016 Feb 18;52(14):3030-3. doi: 10.1039/c5cc09724j.

46.

Multiband RF pulses with improved performance via convex optimization.

Shang H, Larson PEZ, Kerr A, Reed G, Sukumar S, Elkhaled A, Gordon JW, Ohliger MA, Pauly JM, Lustig M, Vigneron DB.

J Magn Reson. 2016 Jan;262:81-90. doi: 10.1016/j.jmr.2015.11.010. Epub 2015 Dec 14.

47.

Ultrashort echo time and zero echo time MRI at 7T.

Larson PE, Han M, Krug R, Jakary A, Nelson SJ, Vigneron DB, Henry RG, McKinnon G, Kelley DA.

MAGMA. 2016 Jun;29(3):359-70. doi: 10.1007/s10334-015-0509-0. Epub 2015 Dec 24.

48.

Development and testing of hyperpolarized (13)C MR calibrationless parallel imaging.

Feng Y, Gordon JW, Shin PJ, von Morze C, Lustig M, Larson PEZ, Ohliger MA, Carvajal L, Tropp J, Pauly JM, Vigneron DB.

J Magn Reson. 2016 Jan;262:1-7. doi: 10.1016/j.jmr.2015.10.018. Epub 2015 Oct 31.

49.

Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI.

Flavell RR, von Morze C, Blecha JE, Korenchan DE, Van Criekinge M, Sriram R, Gordon JW, Chen HY, Subramaniam S, Bok RA, Wang ZJ, Vigneron DB, Larson PE, Kurhanewicz J, Wilson DM.

Chem Commun (Camb). 2015 Sep 25;51(74):14119-22. doi: 10.1039/c5cc05348j.

50.

Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor.

Sriram R, Van Criekinge M, Hansen A, Wang ZJ, Vigneron DB, Wilson DM, Keshari KR, Kurhanewicz J.

NMR Biomed. 2015 Sep;28(9):1141-9. doi: 10.1002/nbm.3354. Epub 2015 Jul 23.

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