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Items: 1 to 50 of 192

1.

Soluble IL-7 receptor alpha concentration in cord blood is linked to sex and maternal diabetes, but not with subsequent development of type 1 diabetes.

Monti P, Vignali D, Ziegler AG, Bonifacio E.

Eur J Immunol. 2020 Feb 13. doi: 10.1002/eji.201948447. [Epub ahead of print] No abstract available.

PMID:
32056201
2.

B cell-Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer.

Mirlekar B, Michaud D, Lee SJ, Kren NP, Harris C, Greene K, Goldman EC, Gupta GP, Fields RC, Hawkins WG, DeNardo DG, Rashid NU, Yeh JJ, McRee AJ, Vincent BG, Vignali DAA, Pylayeva-Gupta Y.

Cancer Immunol Res. 2020 Mar;8(3):292-308. doi: 10.1158/2326-6066.CIR-19-0349. Epub 2020 Feb 5.

3.

Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1+ Cells.

Cortese N, Capretti G, Barbagallo M, Rigamonti A, Takis PG, Castino GF, Vignali D, Maggi G, Gavazzi F, Ridolfi C, Nappo G, Donisi G, Erreni M, Avigni R, Rahal D, Spaggiari P, Roncalli M, Cappello P, Novelli F, Monti P, Zerbi A, Allavena P, Mantovani A, Marchesi F.

Cancer Immunol Res. 2020 Apr;8(4):493-505. doi: 10.1158/2326-6066.CIR-19-0403. Epub 2020 Feb 4.

PMID:
32019781
4.

Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance.

Sullivan JA, Tomita Y, Jankowska-Gan E, Lema DA, Arvedson MP, Nair A, Bracamonte-Baran W, Zhou Y, Meyer KK, Zhong W, Sawant DV, Szymczak-Workman AL, Zhang Q, Workman CJ, Hong S, Vignali DAA, Burlingham WJ.

Cell Rep. 2020 Jan 28;30(4):1039-1051.e5. doi: 10.1016/j.celrep.2019.12.081.

5.

Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer.

Cillo AR, Kürten CHL, Tabib T, Qi Z, Onkar S, Wang T, Liu A, Duvvuri U, Kim S, Soose RJ, Oesterreich S, Chen W, Lafyatis R, Bruno TC, Ferris RL, Vignali DAA.

Immunity. 2020 Jan 14;52(1):183-199.e9. doi: 10.1016/j.immuni.2019.11.014. Epub 2020 Jan 7.

PMID:
31924475
6.

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery.

Liu B, Hood JD, Kolawole EM, Woodruff DM, Vignali DA, Bettini M, Evavold BD.

Diabetes. 2020 Mar;69(3):381-391. doi: 10.2337/db19-0399. Epub 2019 Dec 5.

PMID:
31806623
7.

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors.

Zhu L, Narloch JL, Onkar S, Joy M, Broadwater G, Luedke C, Hall A, Kim R, Pogue-Geile K, Sammons S, Nayyar N, Chukwueke U, Brastianos PK, Anders CK, Soloff AC, Vignali DAA, Tseng GC, Emens LA, Lucas PC, Blackwell KL, Oesterreich S, Lee AV.

J Immunother Cancer. 2019 Oct 18;7(1):265. doi: 10.1186/s40425-019-0755-1.

8.

Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups.

Andrews LP, Yano H, Vignali DAA.

Nat Immunol. 2019 Nov;20(11):1425-1434. doi: 10.1038/s41590-019-0512-0. Epub 2019 Oct 14. Review.

PMID:
31611702
9.

Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor.

Ruffo E, Wu RC, Bruno TC, Workman CJ, Vignali DAA.

Semin Immunol. 2019 Apr;42:101305. doi: 10.1016/j.smim.2019.101305. Review.

10.

Pharmacological Targeting of GLUT1 to Control Autoreactive T Cell Responses.

Di Dedda C, Vignali D, Piemonti L, Monti P.

Int J Mol Sci. 2019 Oct 8;20(19). pii: E4962. doi: 10.3390/ijms20194962. Review.

11.

Pancreatic cancer-associated inflammation drives dynamic regulation of p35 and Ebi3.

Michaud D, Mirlekar B, Bischoff S, Cowley DO, Vignali DAA, Pylayeva-Gupta Y.

Cytokine. 2020 Jan;125:154817. doi: 10.1016/j.cyto.2019.154817. Epub 2019 Aug 28.

PMID:
31472403
12.

Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.

Liu C, Chikina M, Deshpande R, Menk AV, Wang T, Tabib T, Brunazzi EA, Vignali KM, Sun M, Stolz DB, Lafyatis RA, Chen W, Delgoffe GM, Workman CJ, Wendell SG, Vignali DAA.

Immunity. 2019 Aug 20;51(2):381-397.e6. doi: 10.1016/j.immuni.2019.06.017. Epub 2019 Jul 23.

PMID:
31350177
13.

Intratumoral regulatory T cells: markers, subsets and their impact on anti-tumor immunity.

Yano H, Andrews LP, Workman CJ, Vignali DAA.

Immunology. 2019 Jul;157(3):232-247. doi: 10.1111/imm.13067. Epub 2019 Jun 3. Review.

PMID:
31087644
14.

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies.

Sun Z, Chen L, Xin H, Jiang Y, Huang Q, Cillo AR, Tabib T, Kolls JK, Bruno TC, Lafyatis R, Vignali DAA, Chen K, Ding Y, Hu M, Chen W.

Nat Commun. 2019 Apr 9;10(1):1649. doi: 10.1038/s41467-019-09639-3.

15.

Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion.

Sawant DV, Yano H, Chikina M, Zhang Q, Liao M, Liu C, Callahan DJ, Sun Z, Sun T, Tabib T, Pennathur A, Corry DB, Luketich JD, Lafyatis R, Chen W, Poholek AC, Bruno TC, Workman CJ, Vignali DAA.

Nat Immunol. 2019 Jun;20(6):724-735. doi: 10.1038/s41590-019-0346-9. Epub 2019 Apr 1.

16.

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.

Wang J, Sanmamed MF, Datar I, Su TT, Ji L, Sun J, Chen L, Chen Y, Zhu G, Yin W, Zheng L, Zhou T, Badri T, Yao S, Zhu S, Boto A, Sznol M, Melero I, Vignali DAA, Schalper K, Chen L.

Cell. 2019 Jan 10;176(1-2):334-347.e12. doi: 10.1016/j.cell.2018.11.010. Epub 2018 Dec 20.

17.

Treg Fragility: A Prerequisite for Effective Antitumor Immunity?

Overacre-Delgoffe AE, Vignali DAA.

Cancer Immunol Res. 2018 Aug;6(8):882-887. doi: 10.1158/2326-6066.CIR-18-0066. Review.

18.

Quantifying the contribution of intracranial pressure and arterial blood pressure to spontaneous tympanic membrane displacement.

El-Bouri WK, Vignali D, Iliadi K, Bulters D, Marchbanks RJ, Birch AA, Simpson DM.

Physiol Meas. 2018 Aug 8;39(8):085002. doi: 10.1088/1361-6579/aad308.

PMID:
29999499
19.

B7-H4 Modulates Regulatory CD4+ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex.

Podojil JR, Chiang MY, Ifergan I, Copeland R, Liu LN, Maloveste S, Langermann S, Liebenson D, Balabanov R, Chi H, Chen L, Vignali DAA, Miller SD.

J Immunol. 2018 Aug 1;201(3):897-907. doi: 10.4049/jimmunol.1700811. Epub 2018 Jun 13.

20.

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.

Du T, Zhu L, Levine KM, Tasdemir N, Lee AV, Vignali DAA, Houten BV, Tseng GC, Oesterreich S.

Sci Rep. 2018 May 8;8(1):7205. doi: 10.1038/s41598-018-25357-0.

21.

Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes.

Vignali D, Cantarelli E, Bordignon C, Canu A, Citro A, Annoni A, Piemonti L, Monti P.

Diabetes. 2018 May;67(5):936-945. doi: 10.2337/db17-1390. Epub 2018 Mar 5.

22.

Opening the Door for Immune Oncology Studies in Invasive Lobular Breast Cancer.

Oesterreich S, Lucas PC, McAuliffe PF, Bruno TC, Vignali DAA.

J Natl Cancer Inst. 2018 Jul 1;110(7):696-698. doi: 10.1093/jnci/djy014. No abstract available.

PMID:
29471462
23.

Reference intervals for the evoked tympanic membrane displacement measurement: a non-invasive measure of intracranial pressure.

Campbell-Bell CM, Birch AA, Vignali D, Bulters D, Marchbanks RJ.

Physiol Meas. 2018 Jan 31;39(1):015008. doi: 10.1088/1361-6579/aaa1d3.

PMID:
29239860
24.

Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity.

Do J, Kim D, Kim S, Valentin-Torres A, Dvorina N, Jang E, Nagarajavel V, DeSilva TM, Li X, Ting AH, Vignali DAA, Stohlman SA, Baldwin WM 3rd, Min B.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10190-10195. doi: 10.1073/pnas.1703100114. Epub 2017 Sep 5.

25.

LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes.

Zhang Q, Chikina M, Szymczak-Workman AL, Horne W, Kolls JK, Vignali KM, Normolle D, Bettini M, Workman CJ, Vignali DAA.

Sci Immunol. 2017 Mar 31;2(9). pii: eaah4569. doi: 10.1126/sciimmunol.aah4569.

26.

Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.

Bettini ML, Chou PC, Guy CS, Lee T, Vignali KM, Vignali DAA.

J Immunol. 2017 Sep 1;199(5):1555-1560. doi: 10.4049/jimmunol.1700069. Epub 2017 Jul 21.

27.

Improving homing in T cell therapy.

Vignali D, Kallikourdis M.

Cytokine Growth Factor Rev. 2017 Aug;36:107-116. doi: 10.1016/j.cytogfr.2017.06.009. Epub 2017 Jun 23. Review.

PMID:
28690108
28.

Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.

Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA.

Cell. 2017 Jun 1;169(6):1130-1141.e11. doi: 10.1016/j.cell.2017.05.005. Epub 2017 May 25.

29.

Treg-recruiting microspheres prevent inflammation in a murine model of dry eye disease.

Ratay ML, Glowacki AJ, Balmert SC, Acharya AP, Polat J, Andrews LP, Fedorchak MV, Schuman JS, Vignali DAA, Little SR.

J Control Release. 2017 Jul 28;258:208-217. doi: 10.1016/j.jconrel.2017.05.007. Epub 2017 May 10.

PMID:
28501670
30.

Globule Leukocytes and Other Mast Cells in the Mouse Intestine.

Vogel P, Janke L, Gravano DM, Lu M, Sawant DV, Bush D, Shuyu E, Vignali DAA, Pillai A, Rehg JE.

Vet Pathol. 2018 Jan;55(1):76-97. doi: 10.1177/0300985817705174. Epub 2017 May 11.

PMID:
28494703
31.

T cell costimulation blockade blunts pressure overload-induced heart failure.

Kallikourdis M, Martini E, Carullo P, Sardi C, Roselli G, Greco CM, Vignali D, Riva F, Ormbostad Berre AM, Stølen TO, Fumero A, Faggian G, Di Pasquale E, Elia L, Rumio C, Catalucci D, Papait R, Condorelli G.

Nat Commun. 2017 Mar 6;8:14680. doi: 10.1038/ncomms14680.

32.

LAG3 (CD223) as a cancer immunotherapy target.

Andrews LP, Marciscano AE, Drake CG, Vignali DA.

Immunol Rev. 2017 Mar;276(1):80-96. doi: 10.1111/imr.12519. Review.

33.

Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?

Visperas A, Vignali DA.

J Immunol. 2016 Nov 15;197(10):3762-3770. Review.

34.

Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.

Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, Andrabi SA, Kang SU, Gonçalves RA, Liang Y, Zhang S, Qi C, Lam S, Keiler JA, Tyson J, Kim D, Panicker N, Yun SP, Workman CJ, Vignali DA, Dawson VL, Ko HS, Dawson TM.

Science. 2016 Sep 30;353(6307). pii: aah3374.

35.

Kinetics of Alloantigen-Specific Regulatory CD4 T Cell Development and Tissue Distribution After Donor-Specific Transfusion and Costimulatory Blockade.

Tomita Y, Satomi M, Bracamonte-Baran W, Jankowska Gan E, Workman AS, Workman CJ, Vignali DA, Burlingham WJ.

Transplant Direct. 2016 Apr 21;2(5):e73. doi: 10.1097/TXD.0000000000000580. eCollection 2016 May.

36.

Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.

Dobbins J, Gagnon E, Godec J, Pyrdol J, Vignali DA, Sharpe AH, Wucherpfennig KW.

Sci Signal. 2016 Jul 26;9(438):ra75. doi: 10.1126/scisignal.aaf0626.

37.

IL-7 Mediated Homeostatic Expansion of Human CD4+CD25+FOXP3+ Regulatory T Cells After Depletion With Anti-CD25 Monoclonal Antibody.

Vignali D, Gürth CM, Pellegrini S, Sordi V, Sizzano F, Piemonti L, Monti P.

Transplantation. 2016 Sep;100(9):1853-61. doi: 10.1097/TP.0000000000001276.

PMID:
27306531
38.

Co-stimulatory and Co-inhibitory Pathways in Autoimmunity.

Zhang Q, Vignali DA.

Immunity. 2016 May 17;44(5):1034-51. doi: 10.1016/j.immuni.2016.04.017. Review.

39.

Tailored chemokine receptor modification improves homing of adoptive therapy T cells in a spontaneous tumor model.

Garetto S, Sardi C, Martini E, Roselli G, Morone D, Angioni R, Cianciotti BC, Trovato AE, Franchina DG, Castino GF, Vignali D, Erreni M, Marchesi F, Rumio C, Kallikourdis M.

Oncotarget. 2016 Jul 12;7(28):43010-43026. doi: 10.18632/oncotarget.9280.

40.

Targeting Homeostatic T Cell Proliferation to Control Beta-Cell Autoimmunity.

Vignali D, Monti P.

Curr Diab Rep. 2016 May;16(5):40. doi: 10.1007/s11892-016-0731-9. Review.

41.

Interleukin-35 Limits Anti-Tumor Immunity.

Turnis ME, Sawant DV, Szymczak-Workman AL, Andrews LP, Delgoffe GM, Yano H, Beres AJ, Vogel P, Workman CJ, Vignali DA.

Immunity. 2016 Feb 16;44(2):316-29. doi: 10.1016/j.immuni.2016.01.013. Epub 2016 Feb 9.

42.

Targeting regulatory T cells in tumors.

Liu C, Workman CJ, Vignali DA.

FEBS J. 2016 Jul;283(14):2731-48. doi: 10.1111/febs.13656. Epub 2016 Mar 1. Review.

43.

T(reg) stability: to be or not to be.

Overacre AE, Vignali DA.

Curr Opin Immunol. 2016 Apr;39:39-43. doi: 10.1016/j.coi.2015.12.009. Epub 2016 Jan 15. Review.

44.

Mucosal Administration of Collagen V Ameliorates the Atherosclerotic Plaque Burden by Inducing Interleukin 35-dependent Tolerance.

Park AC, Huang G, Jankowska-Gan E, Massoudi D, Kernien JF, Vignali DA, Sullivan JA, Wilkes DS, Burlingham WJ, Greenspan DS.

J Biol Chem. 2016 Feb 12;291(7):3359-70. doi: 10.1074/jbc.M115.681882. Epub 2015 Dec 31.

45.

Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR.

He Y, Rangarajan S, Kerzic M, Luo M, Chen Y, Wang Q, Yin Y, Workman CJ, Vignali KM, Vignali DA, Mariuzza RA, Orban J.

J Biol Chem. 2015 Aug 7;290(32):19796-805. doi: 10.1074/jbc.M115.663799. Epub 2015 Jun 24.

46.

Inhibitory receptors as targets for cancer immunotherapy.

Turnis ME, Andrews LP, Vignali DA.

Eur J Immunol. 2015 Jul;45(7):1892-905. doi: 10.1002/eji.201344413. Review.

47.

An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy.

Do JS, Visperas A, Sanogo YO, Bechtel JJ, Dvorina N, Kim S, Jang E, Stohlman SA, Shen B, Fairchild RL, Baldwin WM III, Vignali DA, Min B.

Mucosal Immunol. 2016 Jan;9(1):137-45. doi: 10.1038/mi.2015.45. Epub 2015 May 27.

48.

Interleukin-35: Expanding Its Job Profile.

Sawant DV, Hamilton K, Vignali DA.

J Interferon Cytokine Res. 2015 Jul;35(7):499-512. doi: 10.1089/jir.2015.0015. Epub 2015 Apr 28. Review.

49.

Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members.

Dixon KO, van der Kooij SW, Vignali DA, van Kooten C.

Eur J Immunol. 2015 Jun;45(6):1736-47. doi: 10.1002/eji.201445217.

50.

Monitoring Inflammation, Humoral and Cell-mediated Immunity in Pancreas and Islet Transplants.

Monti P, Vignali D, Piemonti L.

Curr Diabetes Rev. 2015;11(3):135-43. Review.

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