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Items: 22


Efficient and Robust Paramyxoviridae Reverse Genetics Systems.

Beaty SM, Park A, Won ST, Hong P, Lyons M, Vigant F, Freiberg AN, tenOever BR, Duprex WP, Lee B.

mSphere. 2017 Mar 29;2(2). pii: e00376-16. doi: 10.1128/mSphere.00376-16. eCollection 2017 Mar-Apr.


Inhibition of an Aquatic Rhabdovirus Demonstrates Promise of a Broad-Spectrum Antiviral for Use in Aquaculture.

Balmer BF, Powers RL, Zhang TH, Lee J, Vigant F, Lee B, Jung ME, Purcell MK, Snekvik K, Aguilar HC.

J Virol. 2017 Jan 31;91(4). pii: e02181-16. doi: 10.1128/JVI.02181-16. Print 2017 Feb 15.


Cross-Reactive and Cross-Neutralizing Activity of Human Mumps Antibodies Against a Novel Mumps Virus From Bats.

Beaty SM, Nachbagauer R, Hirsh A, Vigant F, Duehr J, Azarm KD, Stelfox AJ, Bowden TA, Duprex WP, Krammer F, Lee B.

J Infect Dis. 2017 Jan 15;215(2):209-213. doi: 10.1093/infdis/jiw534.


The Microtubule Inhibitor Podofilox Inhibits an Early Entry Step of Human Cytomegalovirus.

Cohen T, Schwarz TM, Vigant F, Gardner TJ, Hernandez RE, Lee B, Tortorella D.

Viruses. 2016 Oct 24;8(10). pii: E295.


Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing.

Park A, Hong P, Won ST, Thibault PA, Vigant F, Oguntuyo KY, Taft JD, Lee B.

Mol Ther Methods Clin Dev. 2016 Aug 24;3:16057. doi: 10.1038/mtm.2016.57. eCollection 2016.


Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway.

Park A, Yun T, Vigant F, Pernet O, Won ST, Dawes BE, Bartkowski W, Freiberg AN, Lee B.

PLoS Pathog. 2016 May 20;12(5):e1005659. doi: 10.1371/journal.ppat.1005659. eCollection 2016 May.


ISG15 deficiency and increased viral resistance in humans but not mice.

Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M, Duehr J, Sanal O, Tezcan I, Mansouri N, Tabarsi P, Mansouri D, Francois-Newton V, Daussy CF, Rodriguez MR, Lenschow DJ, Freiberg AN, Tortorella D, Piehler J, Lee B, García-Sastre A, Pellegrini S, Bogunovic D.

Nat Commun. 2016 May 19;7:11496. doi: 10.1038/ncomms11496.


Pseudotyping Serotype 5 Adenovirus with the Fiber from Other Serotypes Uncovers a Key Role of the Fiber Protein in Adenovirus 5-Induced Thrombocytopenia.

Raddi N, Vigant F, Wagner-Ballon O, Giraudier S, Custers J, Hemmi S, Benihoud K.

Hum Gene Ther. 2016 Feb;27(2):193-201. doi: 10.1089/hum.2015.154.


Broad-spectrum antivirals against viral fusion.

Vigant F, Santos NC, Lee B.

Nat Rev Microbiol. 2015 Jul;13(7):426-37. doi: 10.1038/nrmicro3475. Epub 2015 Jun 15. Review.


Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancer.

Lucas T, Benihoud K, Vigant F, Schmidt CQ, Wortmann A, Bachem MG, Simmet T, Kochanek S.

PLoS One. 2015 Feb 18;10(2):e0117254. doi: 10.1371/journal.pone.0117254. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0123844. Schmidt, Christoph Q Andreas [corrected to Schmidt, Christoph Q]; Wortmann, Andreas [added].


Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection.

Yun T, Park A, Hill TE, Pernet O, Beaty SM, Juelich TL, Smith JK, Zhang L, Wang YE, Vigant F, Gao J, Wu P, Lee B, Freiberg AN.

J Virol. 2015 Jan 15;89(2):1242-53. doi: 10.1128/JVI.02583-14. Epub 2014 Nov 12.


Synthesis and duplex-stabilizing properties of fluorinated N-methanocarbathymidine analogues locked in the C3'-endo conformation.

Jung ME, Dwight TA, Vigant F, Østergaard ME, Swayze EE, Seth PP.

Angew Chem Int Ed Engl. 2014 Sep 8;53(37):9893-7. doi: 10.1002/anie.201405283. Epub 2014 Jul 15.


The rigid amphipathic fusion inhibitor dUY11 acts through photosensitization of viruses.

Vigant F, Hollmann A, Lee J, Santos NC, Jung ME, Lee B.

J Virol. 2014 Feb;88(3):1849-53. doi: 10.1128/JVI.02907-13. Epub 2013 Nov 27.


A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion.

Vigant F, Lee J, Hollmann A, Tanner LB, Akyol Ataman Z, Yun T, Shui G, Aguilar HC, Zhang D, Meriwether D, Roman-Sosa G, Robinson LR, Juelich TL, Buczkowski H, Chou S, Castanho MA, Wolf MC, Smith JK, Banyard A, Kielian M, Reddy S, Wenk MR, Selke M, Santos NC, Freiberg AN, Jung ME, Lee B.

PLoS Pathog. 2013;9(4):e1003297. doi: 10.1371/journal.ppat.1003297. Epub 2013 Apr 18.


Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo.

Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B.

J Virol. 2013 Feb;87(4):2094-108. doi: 10.1128/JVI.02032-12. Epub 2012 Nov 28. Erratum in: J Virol. 2013 Apr;87(8):4794.


Hendra and nipah infection: pathology, models and potential therapies.

Vigant F, Lee B.

Infect Disord Drug Targets. 2011 Jun;11(3):315-36. Review.


Positive reinforcement for viruses.

Vigant F, Jung M, Lee B.

Chem Biol. 2010 Oct 29;17(10):1049-51. doi: 10.1016/j.chembiol.2010.10.002.


Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid.

Jullienne B, Vigant F, Muth E, Chaligné R, Bouquet C, Giraudier S, Perricaudet M, Benihoud K.

Gene Ther. 2009 Dec;16(12):1405-15. doi: 10.1038/gt.2009.97.


Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention.

Franciszkiewicz K, Le Floc'h A, Jalil A, Vigant F, Robert T, Vergnon I, Mackiewicz A, Benihoud K, Validire P, Chouaib S, Combadière C, Mami-Chouaib F.

Cancer Res. 2009 Aug 1;69(15):6249-55. doi: 10.1158/0008-5472.CAN-08-3571. Epub 2009 Jul 28.


Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver.

Vigant F, Descamps D, Jullienne B, Esselin S, Connault E, Opolon P, Tordjmann T, Vigne E, Perricaudet M, Benihoud K.

Mol Ther. 2008 Aug;16(8):1474-80. doi: 10.1038/mt.2008.132. Epub 2008 Jun 17.


Adenoviral-mediated TGF-beta1 inhibition in a mouse model of myelofibrosis inhibit bone marrow fibrosis development.

Gastinne T, Vigant F, Lavenu-Bombled C, Wagner-Ballon O, Tulliez M, Chagraoui H, Villeval JL, Lacout C, Perricaudet M, Vainchenker W, Benihoud K, Giraudier S.

Exp Hematol. 2007 Jan;35(1):64-74.


Expression of non-signaling membrane-anchored death receptors protects murine livers in different models of hepatitis.

Descamps D, Vigant F, Esselin S, Connault E, Opolon P, Perricaudet M, Benihoud K.

Hepatology. 2006 Aug;44(2):399-409.


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