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Items: 8

1.

Unifying photocycle model for light adaptation and temporal evolution of cation conductance in channelrhodopsin-2.

Kuhne J, Vierock J, Tennigkeit SA, Dreier MA, Wietek J, Petersen D, Gavriljuk K, El-Mashtoly SF, Hegemann P, Gerwert K.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9380-9389. doi: 10.1073/pnas.1818707116. Epub 2019 Apr 19.

2.

Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin.

Fudim R, Szczepek M, Vierock J, Vogt A, Schmidt A, Kleinau G, Fischer P, Bartl F, Scheerer P, Hegemann P.

Sci Signal. 2019 Mar 19;12(573). pii: eaav4203. doi: 10.1126/scisignal.aav4203.

PMID:
30890657
3.

Tracking Pore Hydration in Channelrhodopsin by Site-Directed Infrared-Active Azido Probes.

Krause BS, Kaufmann JCD, Kuhne J, Vierock J, Huber T, Sakmar TP, Gerwert K, Bartl FJ, Hegemann P.

Biochemistry. 2019 Mar 5;58(9):1275-1286. doi: 10.1021/acs.biochem.8b01211. Epub 2019 Feb 19.

PMID:
30702875
4.

Crystal structure of the red light-activated channelrhodopsin Chrimson.

Oda K, Vierock J, Oishi S, Rodriguez-Rozada S, Taniguchi R, Yamashita K, Wiegert JS, Nishizawa T, Hegemann P, Nureki O.

Nat Commun. 2018 Sep 26;9(1):3949. doi: 10.1038/s41467-018-06421-9.

5.

Molecular determinants of proton selectivity and gating in the red-light activated channelrhodopsin Chrimson.

Vierock J, Grimm C, Nitzan N, Hegemann P.

Sci Rep. 2017 Aug 30;7(1):9928. doi: 10.1038/s41598-017-09600-8.

6.

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins.

Grimm C, Vierock J, Hegemann P, Wietek J.

J Vis Exp. 2017 May 22;(123). doi: 10.3791/55497.

7.

Optogenetic approaches addressing extracellular modulation of neural excitability.

Ferenczi EA, Vierock J, Atsuta-Tsunoda K, Tsunoda SP, Ramakrishnan C, Gorini C, Thompson K, Lee SY, Berndt A, Perry C, Minniberger S, Vogt A, Mattis J, Prakash R, Delp S, Deisseroth K, Hegemann P.

Sci Rep. 2016 Apr 5;6:23947. doi: 10.1038/srep23947.

8.

The microbial opsin family of optogenetic tools.

Zhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J, Magnuson J, Hegemann P, Deisseroth K.

Cell. 2011 Dec 23;147(7):1446-57. doi: 10.1016/j.cell.2011.12.004.

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