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Items: 10


Distinct niches within the extracellular matrix dictate fibroblast function in (cell free) 3D lung tissue cultures.

Burgstaller G, Sengupta A, Vierkotten S, Preissler G, Lindner M, Behr J, Königshoff M, Eickelberg O.

Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L708-L723. doi: 10.1152/ajplung.00408.2017. Epub 2018 Jan 18.


Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.

Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, Zwickenpflug W, Flockerzi V, Storch U, Yildirim AÖ, Gudermann T, Königshoff M, Dietrich A.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):560-568. doi: 10.1016/j.bbadis.2016.12.002. Epub 2016 Dec 6.


BARD1 mediates TGF-β signaling in pulmonary fibrosis.

André PA, Prêle CM, Vierkotten S, Carnesecchi S, Donati Y, Chambers RC, Pache JC, Crestani B, Barazzone-Argiroffo C, Königshoff M, Laurent GJ, Irminger-Finger I.

Respir Res. 2015 Sep 29;16:118. doi: 10.1186/s12931-015-0278-3.


Multidimensional immunolabeling and 4D time-lapse imaging of vital ex vivo lung tissue.

Burgstaller G, Vierkotten S, Lindner M, Königshoff M, Eickelberg O.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15;309(4):L323-32. doi: 10.1152/ajplung.00061.2015. Epub 2015 Jun 19.


Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells.

Mutze K, Vierkotten S, Milosevic J, Eickelberg O, Königshoff M.

Dis Model Mech. 2015 Aug 1;8(8):877-90. doi: 10.1242/dmm.019117. Epub 2015 May 14.


Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures.

Uhl FE, Vierkotten S, Wagner DE, Burgstaller G, Costa R, Koch I, Lindner M, Meiners S, Eickelberg O, Königshoff M.

Eur Respir J. 2015 Oct;46(4):1150-66. doi: 10.1183/09031936.00183214. Epub 2015 Apr 30.


Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice.

Bühler A, Berger S, Bengsch F, Martin G, Han H, Vierkotten S, Pielen A, Boehringer D, Schlunck G, Fauser S, Agostini HT, Reinheckel T, Stahl A.

Exp Eye Res. 2013 Oct;115:73-8. doi: 10.1016/j.exer.2013.06.014. Epub 2013 Jun 22.


Upregulation of TGF-ß1 in experimental proliferative vitreoretinopathy is accompanied by epithelial to mesenchymal transition.

Hoerster R, Muether PS, Vierkotten S, Hermann MM, Kirchhof B, Fauser S.

Graefes Arch Clin Exp Ophthalmol. 2014 Jan;252(1):11-6. doi: 10.1007/s00417-013-2377-5. Epub 2013 May 17.


In-vivo and ex-vivo characterization of laser-induced choroidal neovascularization variability in mice.

Hoerster R, Muether PS, Vierkotten S, Schröder S, Kirchhof B, Fauser S.

Graefes Arch Clin Exp Ophthalmol. 2012 Nov;250(11):1579-86. doi: 10.1007/s00417-012-1990-z. Epub 2012 Mar 16.


Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components.

Vierkotten S, Muether PS, Fauser S.

PLoS One. 2011;6(8):e22959. doi: 10.1371/journal.pone.0022959. Epub 2011 Aug 2.

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