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Items: 38

1.

High Amounts of S100-Alarmins Confer Antimicrobial Activity on Human Breast Milk Targeting Pathogens Relevant in Neonatal Sepsis.

Pirr S, Richter M, Fehlhaber B, Pagel J, Härtel C, Roth J, Vogl T, Viemann D.

Front Immunol. 2017 Dec 13;8:1822. doi: 10.3389/fimmu.2017.01822. eCollection 2017.

2.

Newborn susceptibility to infection vs. disease depends on complex in vivo interactions of host and pathogen.

Brook B, Harbeson D, Ben-Othman R, Viemann D, Kollmann TR.

Semin Immunopathol. 2017 Nov;39(6):615-625. doi: 10.1007/s00281-017-0651-z. Epub 2017 Nov 2. Review.

PMID:
29098373
3.

Corrigendum: S100-alarmin-induced innate immune programming protects newborn infants from sepsis.

Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D.

Nat Immunol. 2017 Sep 19;18(10):1173. doi: 10.1038/ni1017-1173b. No abstract available.

PMID:
28926540
4.

Lactobacillus acidophilus/Bifidobacterium infantis probiotics are associated with increased growth of VLBWI among those exposed to antibiotics.

Härtel C, Pagel J, Spiegler J, Buma J, Henneke P, Zemlin M, Viemann D, Gille C, Gehring S, Frommhold D, Rupp J, Herting E, Göpel W.

Sci Rep. 2017 Jul 17;7(1):5633. doi: 10.1038/s41598-017-06161-8.

5.

S100-alarmin-induced innate immune programming protects newborn infants from sepsis.

Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D.

Nat Immunol. 2017 Jun;18(6):622-632. doi: 10.1038/ni.3745. Epub 2017 May 1. Erratum in: Nat Immunol. 2017 Sep 19;18(10 ):1173.

PMID:
28459433
6.

In neonates S100A8/S100A9 alarmins prevent the expansion of a specific inflammatory monocyte population promoting septic shock.

Heinemann AS, Pirr S, Fehlhaber B, Mellinger L, Burgmann J, Busse M, Ginzel M, Friesenhagen J, von Köckritz-Blickwede M, Ulas T, von Kaisenberg CS, Roth J, Vogl T, Viemann D.

FASEB J. 2017 Mar;31(3):1153-1164. doi: 10.1096/fj.201601083R. Epub 2016 Dec 19.

PMID:
27993995
7.

Preterm Birth during Influenza Season Is Associated with Adverse Outcome in Very Low Birth Weight Infants.

Härtel C, Humberg A, Viemann D, Stein A, Orlikowsky T, Rupp J, Kopp MV, Herting E, Göpel W.

Front Pediatr. 2016 Nov 30;4:130. eCollection 2016.

8.

Media Stories on NICU Outbreaks Lead to an Increased Prescription Rate of Third-Line Antibiotics in the Community of Neonatal Care.

Härtel C, Hartz A, Bahr L, Gille C, Gortner L, Simon A, Orlikowsky T, Müller A, Körner T, Henneke P, Haase R, Zemlin M, Viemann D, Gebauer C, Thome U, Ziegler A, Rupp J, Herting E, Göpel W; German Neonatal Network.

Infect Control Hosp Epidemiol. 2016 Aug;37(8):924-30. doi: 10.1017/ice.2016.95. Epub 2016 May 4.

PMID:
27143176
9.

Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.

Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T.

J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10.

10.

Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions.

Austermann J, Friesenhagen J, Fassl SK, Petersen B, Ortkras T, Burgmann J, Barczyk-Kahlert K, Faist E, Zedler S, Pirr S, Rohde C, Müller-Tidow C, von Köckritz-Blickwede M, von Kaisenberg CS, Flohé SB, Ulas T, Schultze JL, Roth J, Vogl T, Viemann D.

Cell Rep. 2014 Dec 24;9(6):2112-23. doi: 10.1016/j.celrep.2014.11.020. Epub 2014 Dec 11. Erratum in: Cell Rep. 2015 May 5;11(5):849. Petersen, Beatrix [added].

11.

Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection.

Börgeling Y, Schmolke M, Viemann D, Nordhoff C, Roth J, Ludwig S.

J Biol Chem. 2014 Jan 3;289(1):13-27. doi: 10.1074/jbc.M113.469239. Epub 2013 Nov 4.

12.

Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4.

Foell D, Wittkowski H, Kessel C, Lüken A, Weinhage T, Varga G, Vogl T, Wirth T, Viemann D, Björk P, van Zoelen MA, Gohar F, Srikrishna G, Kraft M, Roth J.

Am J Respir Crit Care Med. 2013 Jun 15;187(12):1324-34. doi: 10.1164/rccm.201209-1602OC.

PMID:
23611140
13.

Highly pathogenic influenza viruses inhibit inflammatory response in monocytes via activation of rar-related orphan receptor RORα.

Friesenhagen J, Viemann D, Börgeling Y, Schmolke M, Spiekermann C, Kirschnek S, Ludwig S, Roth J.

J Innate Immun. 2013;5(5):505-18. doi: 10.1159/000346706. Epub 2013 Feb 22.

14.

Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages.

Friesenhagen J, Boergeling Y, Hrincius E, Ludwig S, Roth J, Viemann D.

J Leukoc Biol. 2012 Jul;92(1):11-20. doi: 10.1189/jlb.0911479. Epub 2012 Mar 21.

15.

Endothelial cells present an innate resistance to glucocorticoid treatment: implications for therapy of primary vasculitis.

Koenen P, Barczyk K, Wolf M, Roth J, Viemann D.

Ann Rheum Dis. 2012 May;71(5):729-36. doi: 10.1136/annrheumdis-2011-200530. Epub 2011 Dec 27.

PMID:
22203687
16.

H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response.

Viemann D, Schmolke M, Lueken A, Boergeling Y, Friesenhagen J, Wittkowski H, Ludwig S, Roth J.

J Immunol. 2011 Jan 1;186(1):164-73. doi: 10.4049/jimmunol.0904170. Epub 2010 Nov 24.

17.

Staphylococcus aureus small-colony variants are adapted phenotypes for intracellular persistence.

Tuchscherr L, Heitmann V, Hussain M, Viemann D, Roth J, von Eiff C, Peters G, Becker K, Löffler B.

J Infect Dis. 2010 Oct 1;202(7):1031-40. doi: 10.1086/656047.

PMID:
20715929
18.

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4).

Ohnesorge N, Viemann D, Schmidt N, Czymai T, Spiering D, Schmolke M, Ludwig S, Roth J, Goebeler M, Schmidt M.

J Biol Chem. 2010 Aug 20;285(34):26199-210. doi: 10.1074/jbc.M110.103127. Epub 2010 Jun 15.

19.

Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3.

Barczyk K, Ehrchen J, Tenbrock K, Ahlmann M, Kneidl J, Viemann D, Roth J.

Blood. 2010 Jul 22;116(3):446-55. doi: 10.1182/blood-2009-10-247106. Epub 2010 May 11.

20.

Keratinocytes determine Th1 immunity during early experimental leishmaniasis.

Ehrchen JM, Roebrock K, Foell D, Nippe N, von Stebut E, Weiss JM, Münck NA, Viemann D, Varga G, Müller-Tidow C, Schuberth HJ, Roth J, Sunderkötter C.

PLoS Pathog. 2010 Apr 29;6(4):e1000871. doi: 10.1371/journal.ppat.1000871.

21.

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome.

Woellner C, Gertz EM, Schäffer AA, Lagos M, Perro M, Glocker EO, Pietrogrande MC, Cossu F, Franco JL, Matamoros N, Pietrucha B, Heropolitańska-Pliszka E, Yeganeh M, Moin M, Español T, Ehl S, Gennery AR, Abinun M, Breborowicz A, Niehues T, Kilic SS, Junker A, Turvey SE, Plebani A, Sánchez B, Garty BZ, Pignata C, Cancrini C, Litzman J, Sanal O, Baumann U, Bacchetta R, Hsu AP, Davis JN, Hammarström L, Davies EG, Eren E, Arkwright PD, Moilanen JS, Viemann D, Khan S, Maródi L, Cant AJ, Freeman AF, Puck JM, Holland SM, Grimbacher B.

J Allergy Clin Immunol. 2010 Feb;125(2):424-432.e8. doi: 10.1016/j.jaci.2009.10.059.

22.

Staphylococcal strains vary greatly in their ability to induce an inflammatory response in endothelial cells.

Grundmeier M, Tuchscherr L, Brück M, Viemann D, Roth J, Willscher E, Becker K, Peters G, Löffler B.

J Infect Dis. 2010 Mar 15;201(6):871-80. doi: 10.1086/651023.

PMID:
20132035
23.

FOXO3 modulates endothelial gene expression and function by classical and alternative mechanisms.

Czymai T, Viemann D, Sticht C, Molema G, Goebeler M, Schmidt M.

J Biol Chem. 2010 Apr 2;285(14):10163-78. doi: 10.1074/jbc.M109.056663. Epub 2010 Feb 1.

24.

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome.

Schmolke M, Viemann D, Roth J, Ludwig S.

J Immunol. 2009 Oct 15;183(8):5180-9. doi: 10.4049/jimmunol.0804198. Epub 2009 Sep 28.

25.

The cyclic AMP response element modulator {alpha} suppresses CD86 expression and APC function.

Ahlmann M, Varga G, Sturm K, Lippe R, Benedyk K, Viemann D, Scholzen T, Ehrchen J, Müller FU, Seidl M, Matus M, Tsokos GC, Roth J, Tenbrock K.

J Immunol. 2009 Apr 1;182(7):4167-74. doi: 10.4049/jimmunol.0802976. Erratum in: J Immunol. 2009 Jul 1;183(1):770.

26.

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression.

Pauli EK, Schmolke M, Wolff T, Viemann D, Roth J, Bode JG, Ludwig S.

PLoS Pathog. 2008 Nov;4(11):e1000196. doi: 10.1371/journal.ppat.1000196. Epub 2008 Nov 7.

27.

Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells.

Müller V, Viemann D, Schmidt M, Endres N, Ludwig S, Leverkus M, Roth J, Goebeler M.

J Immunol. 2007 Dec 15;179(12):8435-45.

28.

Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12.

Wittkowski H, Hirono K, Ichida F, Vogl T, Ye F, Yanlin X, Saito K, Uese K, Miyawaki T, Viemann D, Roth J, Foell D.

Arthritis Rheum. 2007 Dec;56(12):4174-81.

29.

Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome.

Wittkowski H, Sturrock A, van Zoelen MA, Viemann D, van der Poll T, Hoidal JR, Roth J, Foell D.

Crit Care Med. 2007 May;35(5):1369-75.

PMID:
17414728
30.

The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappaB and hypoxia-inducible factor-1alpha.

Viemann D, Schmidt M, Tenbrock K, Schmid S, Müller V, Klimmek K, Ludwig S, Roth J, Goebeler M.

J Immunol. 2007 Mar 1;178(5):3198-207.

31.

MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program.

Viemann D, Barczyk K, Vogl T, Fischer U, Sunderkötter C, Schulze-Osthoff K, Roth J.

Blood. 2007 Mar 15;109(6):2453-60. Epub 2006 Nov 9.

32.

TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells.

Viemann D, Goebeler M, Schmid S, Nordhues U, Klimmek K, Sorg C, Roth J.

J Leukoc Biol. 2006 Jul;80(1):174-85. Epub 2006 Apr 14.

PMID:
16617158
33.

Potentials and pitfalls of DNA array analysis of the endothelial stress response.

Viemann D, Schulze-Osthoff K, Roth J.

Biochim Biophys Acta. 2005 Dec 15;1746(2):73-84. Epub 2005 Oct 26. Review.

34.

Expression of toll-like receptors in neonatal sepsis.

Viemann D, Dubbel G, Schleifenbaum S, Harms E, Sorg C, Roth J.

Pediatr Res. 2005 Oct;58(4):654-9.

PMID:
16189189
35.

Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.

Viemann D, Strey A, Janning A, Jurk K, Klimmek K, Vogl T, Hirono K, Ichida F, Foell D, Kehrel B, Gerke V, Sorg C, Roth J.

Blood. 2005 Apr 1;105(7):2955-62. Epub 2004 Dec 14.

36.

Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells.

Viemann D, Goebeler M, Schmid S, Klimmek K, Sorg C, Ludwig S, Roth J.

Blood. 2004 May 1;103(9):3365-73. Epub 2004 Jan 8.

37.

Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis.

Frosch M, Vogl T, Seeliger S, Wulffraat N, Kuis W, Viemann D, Foell D, Sorg C, Sunderkötter C, Roth J.

Arthritis Rheum. 2003 Sep;48(9):2622-6.

38.

Differential expression of the B cell-restricted molecule CD22 on neonatal B lymphocytes depending upon antigen stimulation.

Viemann D, Schlenke P, Hammers HJ, Kirchner H, Kruse A.

Eur J Immunol. 2000 Feb;30(2):550-9.

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