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Items: 9


The Transcription Factor ZafA Regulates the Homeostatic and Adaptive Response to Zinc Starvation in Aspergillus fumigatus.

Vicentefranqueira R, Amich J, Marín L, Sánchez CI, Leal F, Calera JA.

Genes (Basel). 2018 Jun 26;9(7). pii: E318. doi: 10.3390/genes9070318.


A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism.

Laskaris P, Vicentefranqueira R, Helynck O, Jouvion G, Calera JA, du Merle L, Suzenet F, Buron F, de Sousa RA, Mansuy D, Cavaillon JM, Latgé JP, Munier-Lehmann H, Ibrahim-Granet O.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02510-17. doi: 10.1128/AAC.02510-17. Print 2018 Jun.


Targeting zinc homeostasis to combat Aspergillus fumigatus infections.

Vicentefranqueira R, Amich J, Laskaris P, Ibrahim-Granet O, Latgé JP, Toledo H, Leal F, Calera JA.

Front Microbiol. 2015 Feb 27;6:160. doi: 10.3389/fmicb.2015.00160. eCollection 2015.


The ZrfC alkaline zinc transporter is required for Aspergillus fumigatus virulence and its growth in the presence of the Zn/Mn-chelating protein calprotectin.

Amich J, Vicentefranqueira R, Mellado E, Ruiz-Carmuega A, Leal F, Calera JA.

Cell Microbiol. 2014 Apr;16(4):548-64. doi: 10.1111/cmi.12238. Epub 2013 Dec 4.


Aspergillus fumigatus survival in alkaline and extreme zinc-limiting environments relies on the induction of a zinc homeostasis system encoded by the zrfC and aspf2 genes.

Amich J, Vicentefranqueira R, Leal F, Calera JA.

Eukaryot Cell. 2010 Mar;9(3):424-37. doi: 10.1128/EC.00348-09. Epub 2009 Dec 28.


Culture conditions for zinc- and pH-regulated gene expression studies in Aspergillus fumigatus.

Moreno MA, Amich J, Vicentefranqueira R, Leal F, Calera JA.

Int Microbiol. 2007 Sep;10(3):187-92.


The regulation of zinc homeostasis by the ZafA transcriptional activator is essential for Aspergillus fumigatus virulence.

Moreno MA, Ibrahim-Granet O, Vicentefranqueira R, Amich J, Ave P, Leal F, Latgé JP, Calera JA.

Mol Microbiol. 2007 Jun;64(5):1182-97.

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