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Circulating extracellular vesicle-associated TGFβ3 modulates response to cytotoxic therapy in head and neck squamous cell carcinoma.

Rodrigues-Junior DM, Tan SS, Lim SK, Leong HS, Melendez ME, Ramos CRN, Viana LS, Tan DSW, Carvalho AL, Iyer NG, Vettore AL.

Carcinogenesis. 2019 Aug 22. pii: bgz148. doi: 10.1093/carcin/bgz148. [Epub ahead of print]


Assessment of the cytotoxic effects of aporphine prototypes on head and neck cancer cells.

Rodrigues-Junior DM, de Almeida Pontes NM, de Albuquerque GE, Carlin V, Perecim GP, Raminelli C, Vettore AL.

Invest New Drugs. 2019 May 17. doi: 10.1007/s10637-019-00784-6. [Epub ahead of print]


Downregulation of DCC sensitizes multiple myeloma cells to bortezomib treatment.

Rodrigues-Junior DM, Biassi TP, de Albuquerque GE, Carlin V, Buri MV, Machado-Junior J, Vettore AL.

Mol Med Rep. 2019 Jun;19(6):5023-5029. doi: 10.3892/mmr.2019.10142. Epub 2019 Apr 9.


A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma.

Rodrigues-Junior DM, Tan SS, de Souza Viana L, Carvalho AL, Lim SK, Iyer NG, Vettore AL.

BMC Cancer. 2019 Apr 23;19(1):373. doi: 10.1186/s12885-019-5565-9.


High expression of MLANA in the plasma of patients with head and neck squamous cell carcinoma as a predictor of tumor progression.

Rodrigues-Junior DM, Tan SS, Lim SK, de Souza Viana L, Carvalho AL, Vettore AL, Iyer NG.

Head Neck. 2019 May;41(5):1199-1205. doi: 10.1002/hed.25510. Epub 2019 Feb 25.


OIP5 Expression Sensitize Glioblastoma Cells to Lomustine Treatment.

Rodrigues-Junior DM, Biassi TP, Carlin V, Buri MV, Torrecilhas AC, Bortoluci KR, Vettore AL.

J Mol Neurosci. 2018 Nov;66(3):383-389. doi: 10.1007/s12031-018-1184-1. Epub 2018 Oct 3.


Expression and Prognostic Relevance of GAGE1 and XAGE1 Cancer/Testis Antigens in Head and Neck Squamous Cell Carcinoma.

Karia BTR, Zamuner FT, Carlin V, de Oliveira CZ, Carvalho AL, Vettore AL.

Curr Mol Med. 2017;17(10):707-717. doi: 10.2174/1566524018666180322162145.


In vitro and in silico validation of CA3 and FHL1 downregulation in oral cancer.

Pereira CM, de Carvalho AC, da Silva FR, Melendez ME, Lessa RC, Andrade VCC, Kowalski LP, Vettore AL, Carvalho AL.

BMC Cancer. 2018 Feb 17;18(1):193. doi: 10.1186/s12885-018-4077-3.


Technical challenges of working with extracellular vesicles.

Ramirez MI, Amorim MG, Gadelha C, Milic I, Welsh JA, Freitas VM, Nawaz M, Akbar N, Couch Y, Makin L, Cooke F, Vettore AL, Batista PX, Freezor R, Pezuk JA, Rosa-Fernandes L, Carreira ACO, Devitt A, Jacobs L, Silva IT, Coakley G, Nunes DN, Carter D, Palmisano G, Dias-Neto E.

Nanoscale. 2018 Jan 18;10(3):881-906. doi: 10.1039/c7nr08360b. Review.


Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.

Jusakul A, Cutcutache I, Yong CH, Lim JQ, Huang MN, Padmanabhan N, Nellore V, Kongpetch S, Ng AWT, Ng LM, Choo SP, Myint SS, Thanan R, Nagarajan S, Lim WK, Ng CCY, Boot A, Liu M, Ong CK, Rajasegaran V, Lie S, Lim AST, Lim TH, Tan J, Loh JL, McPherson JR, Khuntikeo N, Bhudhisawasdi V, Yongvanit P, Wongkham S, Totoki Y, Nakamura H, Arai Y, Yamasaki S, Chow PK, Chung AYF, Ooi LLPJ, Lim KH, Dima S, Duda DG, Popescu I, Broet P, Hsieh SY, Yu MC, Scarpa A, Lai J, Luo DX, Carvalho AL, Vettore AL, Rhee H, Park YN, Alexandrov LB, Gordân R, Rozen SG, Shibata T, Pairojkul C, Teh BT, Tan P.

Cancer Discov. 2017 Oct;7(10):1116-1135. doi: 10.1158/2159-8290.CD-17-0368. Epub 2017 Jun 30.


Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck.

Huang KK, Jang KW, Kim S, Kim HS, Kim SM, Kwon HJ, Kim HR, Yun HJ, Ahn MJ, Park KU, Ramnarayanan K, McPherson JR, Zhang S, Rhee JK, Vettore AL, Das K, Ishimoto T, Kim JH, Koh YW, Kim SH, Choi EC, Teh BT, Rozen SG, Kim TM, Tan P, Cho BC.

Sci Rep. 2016 Jan 21;6:19552. doi: 10.1038/srep19552.


Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.

Vettore AL, Ramnarayanan K, Poore G, Lim K, Ong CK, Huang KK, Leong HS, Chong FT, Lim TK, Lim WK, Cutcutache I, Mcpherson JR, Suzuki Y, Zhang S, Skanthakumar T, Wang W, Tan DS, Cho BC, Teh BT, Rozen S, Tan P, Iyer NG.

Genome Med. 2015 Sep 23;7:98. doi: 10.1186/s13073-015-0219-2.


Expression of miR-296-5p as predictive marker for radiotherapy resistance in early-stage laryngeal carcinoma.

Maia D, de Carvalho AC, Horst MA, Carvalho AL, Scapulatempo-Neto C, Vettore AL.

J Transl Med. 2015 Aug 12;13:262. doi: 10.1186/s12967-015-0621-y.


Erratum: Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma.

de Carvalho AC, Scapulatempo-Neto C, Maia DC, Evangelista AF, Morini MA, Carvalho AL, Vettore AL.

BMC Med. 2015 Jul 1;13:155. doi: 10.1186/s12916-015-0406-4. No abstract available.


Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma.

de Carvalho AC, Scapulatempo-Neto C, Maia DC, Evangelista AF, Morini MA, Carvalho AL, Vettore AL.

BMC Med. 2015 May 9;13:108. doi: 10.1186/s12916-015-0350-3. Erratum in: BMC Med. 2015;13:155.


A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.

Zamunér FT, Karia BT, de Oliveira CZ, Santos CR, Carvalho AL, Vettore AL.

Mol Cancer Ther. 2015 Mar;14(3):828-34. doi: 10.1158/1535-7163.MCT-14-0796. Epub 2015 Jan 6.


TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors.

Rettori MM, de Carvalho AC, Longo AL, de Oliveira CZ, Kowalski LP, Carvalho AL, Vettore AL.

J Transl Med. 2013 Dec 20;11:316. doi: 10.1186/1479-5876-11-316.


Aberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma.

Sonaglio V, de Carvalho AC, Toledo SR, Salinas-Souza C, Carvalho AL, Petrilli AS, de Camargo B, Vettore AL.

Onco Targets Ther. 2013 Jun 17;6:713-23. doi: 10.2147/OTT.S44918. Print 2013.


Search for mutations in signaling pathways in head and neck squamous cell carcinoma.

De Carvalho TG, De Carvalho AC, Maia DC, Ogawa JK, Carvalho AL, Vettore AL.

Oncol Rep. 2013 Jul;30(1):334-40. doi: 10.3892/or.2013.2455. Epub 2013 May 13.


Evaluation of the methylation profile of exfoliated cell samples from patients with head and neck squamous cell carcinoma.

Longo AL, Rettori MM, de Carvalho AC, Kowalski LP, Carvalho AL, Vettore AL.

Head Neck. 2014 May;36(5):631-7. doi: 10.1002/hed.23345. Epub 2013 Jul 2.


Expression of cancer/testis antigens is correlated with improved survival in glioblastoma.

Freitas M, Malheiros S, Stávale JN, Biassi TP, Zamunér FT, de Souza Begnami M, Soares FA, Vettore AL.

Oncotarget. 2013 Apr;4(4):636-46.


Prognostic significance of TIMP3 hypermethylation in post-treatment salivary rinse from head and neck squamous cell carcinoma patients.

Rettori MM, de Carvalho AC, Bomfim Longo AL, de Oliveira CZ, Kowalski LP, Carvalho AL, Vettore AL.

Carcinogenesis. 2013 Jan;34(1):20-7. doi: 10.1093/carcin/bgs311. Epub 2012 Oct 5.


Identification of upregulated genes in oral squamous cell carcinomas.

Lessa RC, Campos AH, Freitas CE, Silva FR, Kowalski LP, Carvalho AL, Vettore AL.

Head Neck. 2013 Oct;35(10):1475-81. doi: 10.1002/hed.23169. Epub 2012 Sep 18.


Cancer/Testis Antigen MAGE-C1/CT7: new target for multiple myeloma therapy.

de Carvalho F, Vettore AL, Colleoni GW.

Clin Dev Immunol. 2012;2012:257695. doi: 10.1155/2012/257695. Epub 2012 Mar 11. Review.


Clinical significance of molecular alterations in histologically negative surgical margins of head and neck cancer patients.

de Carvalho AC, Kowalski LP, Campos AH, Soares FA, Carvalho AL, Vettore AL.

Oral Oncol. 2012 Mar;48(3):240-8. doi: 10.1016/j.oraloncology.2011.10.018. Epub 2011 Nov 21.


Evaluation of LAGE-1 and NY-ESO-1 expression in multiple myeloma patients to explore possible benefits of their homology for immunotherapy.

de Carvalho F, Vettore AL, Inaoka RJ, Karia B, Andrade VC, Gnjatic S, Jungbluth AA, Colleoni GW.

Cancer Immun. 2011 Jan 20;11:1.


Claudin-7 down-regulation is an important feature in oral squamous cell carcinoma.

Lourenço SV, Coutinho-Camillo CM, Buim ME, de Carvalho AC, Lessa RC, Pereira CM, Vettore AL, Carvalho AL, Fregnani JH, Kowalski LP, Soares FA.

Histopathology. 2010 Nov;57(5):689-98. doi: 10.1111/j.1365-2559.2010.03685.x.


Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy.

Andrade VC, Vettore AL, Panepucci RA, Almeida MS, Yamamoto M, De Carvalho F, Caballero OL, Zago MA, Colleoni GW.

Leuk Lymphoma. 2010 Aug;51(8):1543-9. doi: 10.3109/10428194.2010.491136.


Comparative expression of a set of genes to an internal housekeeping control in CDNA amplified and not amplified by PolyAPCR in non-Hodgkin's lymphoma samples obtained from fine-needle aspiration cytology.

Corbi FC, Inaoka RJ, Felix RS, Andrade VC, Etto LY, Vettore AL, Franco MF, Colleoni GW.

Diagn Mol Pathol. 2010 Mar;19(1):40-4. doi: 10.1097/PDM.0b013e3181b0b618.


MT1G hypermethylation: a potential prognostic marker for hepatoblastoma.

Sakamoto LH, DE Camargo B, Cajaiba M, Soares FA, Vettore AL.

Pediatr Res. 2010 Apr;67(4):387-93. doi: 10.1203/PDR.0b013e3181d01863.


Expression of eight genes of nuclear factor-kappa B pathway in multiple myeloma using bone marrow aspirates obtained at diagnosis.

Sampaio MS, Vettore AL, Yamamoto M, Chauffaille Mde L, Zago MA, Colleoni GW.

Histol Histopathol. 2009 Aug;24(8):991-7. doi: 10.14670/HH-24.991.


TGFbetaR2 aberrant methylation is a potential prognostic marker and therapeutic target in multiple myeloma.

de Carvalho F, Colleoni GW, Almeida MS, Carvalho AL, Vettore AL.

Int J Cancer. 2009 Oct 15;125(8):1985-91. doi: 10.1002/ijc.24431.


Frequency and prognostic relevance of cancer testis antigen 45 expression in multiple myeloma.

Andrade VC, Vettore AL, Regis Silva MR, Felix RS, Almeida MS, de Carvalho F, Zago MA, Caballero OL, Simpson AJ, Colleoni GW.

Exp Hematol. 2009 Apr;37(4):446-9. doi: 10.1016/j.exphem.2008.12.003. Epub 2009 Feb 10.


SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis.

Felix RS, Colleoni GW, Caballero OL, Yamamoto M, Almeida MS, Andrade VC, Chauffaille Mde L, Silva WA Jr, Begnami MD, Soares FA, Simpson AJ, Zago MA, Vettore AL.

Cancer Lett. 2009 Jun 8;278(1):41-8. doi: 10.1016/j.canlet.2008.12.022. Epub 2009 Jan 25.


Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.

Brait M, Begum S, Carvalho AL, Dasgupta S, Vettore AL, Czerniak B, Caballero OL, Westra WH, Sidransky D, Hoque MO.

Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2786-94. doi: 10.1158/1055-9965.EPI-08-0192.


Glioblastomas: correlation between oligodendroglial components, genetic abnormalities, and prognosis.

Pinto LW, Araújo MB, Vettore AL, Wernersbach L, Leite AC, Chimelli LM, Soares FA.

Virchows Arch. 2008 May;452(5):481-90. doi: 10.1007/s00428-007-0562-9.


Identification of protein-coding and intronic noncoding RNAs down-regulated in clear cell renal carcinoma.

Brito GC, Fachel AA, Vettore AL, Vignal GM, Gimba ER, Campos FS, Barcinski MA, Verjovski-Almeida S, Reis EM.

Mol Carcinog. 2008 Oct;47(10):757-67. doi: 10.1002/mc.20433.


Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients.

Andrade VC, Vettore AL, Felix RS, Almeida MS, Carvalho F, Oliveira JS, Chauffaille ML, Andriolo A, Caballero OL, Zago MA, Colleoni GW.

Cancer Immun. 2008 Feb 1;8:2.


Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6).

Cho HJ, Caballero OL, Gnjatic S, Andrade VC, Colleoni GW, Vettore AL, Outtz HH, Fortunato S, Altorki N, Ferrera CA, Chua R, Jungbluth AA, Chen YT, Old LJ, Simpson AJ.

Cancer Immun. 2006 Dec 1;6:12.


Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas.

Begnami MD, Montagnini AL, Vettore AL, Nonogaki S, Brait M, Simoes-Sato AY, Seixas AQ, Soares FA.

World J Gastroenterol. 2006 Aug 21;12(31):4959-65.


Aberrant methylation in pediatric myelodysplastic syndrome.

Vidal DO, Paixão VA, Brait M, Souto EX, Caballero OL, Lopes LF, Vettore AL.

Leuk Res. 2007 Feb;31(2):175-81. Epub 2006 Aug 4.


Hypermethylation of CpG island in the promoter region of CALCA in acute lymphoblastic leukemia with central nervous system (CNS) infiltration correlates with poorer prognosis.

Paixão VA, Vidal DO, Caballero OL, Vettore AL, Tone LG, Ribeiro KB, Lopes LF.

Leuk Res. 2006 Jul;30(7):891-4. Epub 2006 May 18.


The TP53 mutation, R337H, is associated with Li-Fraumeni and Li-Fraumeni-like syndromes in Brazilian families.

Achatz MI, Olivier M, Le Calvez F, Martel-Planche G, Lopes A, Rossi BM, Ashton-Prolla P, Giugliani R, Palmero EI, Vargas FR, Da Rocha JC, Vettore AL, Hainaut P.

Cancer Lett. 2007 Jan 8;245(1-2):96-102. Epub 2006 Feb 21.


Endosperm-preferred expression of maize genes as revealed by transcriptome-wide analysis of expressed sequence tags.

Verza NC, E Silva TR, Neto GC, Nogueira FT, Fisch PH, de Rosa VE Jr, Rebello MM, Vettore AL, da Silva FR, Arruda P.

Plant Mol Biol. 2005 Sep;59(2):363-74.


Epstein-Barr viral load, interleukin-6 and interleukin-10 levels in post-transplant lymphoproliferative disease: a nested case-control study in a renal transplant cohort.

Baiocchi OC, Colleoni GW, Caballero OL, Vettore AL, Bulgarelli A, Dalbone MA, Granato CF, Franco MF, Pestana JO.

Leuk Lymphoma. 2005 Apr;46(4):533-9.


The mitochondrial genome of the blowfly Chrysomya chloropyga (Diptera: Calliphoridae).

Junqueira AC, Lessinger AC, Torres TT, da Silva FR, Vettore AL, Arruda P, Azeredo Espin AM.

Gene. 2004 Sep 15;339:7-15.


Evaluation of monocot and eudicot divergence using the sugarcane transcriptome.

Vincentz M, Cara FA, Okura VK, da Silva FR, Pedrosa GL, Hemerly AS, Capella AN, Marins M, Ferreira PC, França SC, Grivet L, Vettore AL, Kemper EL, Burnquist WL, Targon ML, Siqueira WJ, Kuramae EE, Marino CL, Camargo LE, Carrer H, Coutinho LL, Furlan LR, Lemos MV, Nunes LR, Gomes SL, Santelli RV, Goldman MH, Bacci M Jr, Giglioti EA, Thiemann OH, Silva FH, Van Sluys MA, Nobrega FG, Arruda P, Menck CF.

Plant Physiol. 2004 Mar;134(3):951-9.


Overexpression, purification, and biochemical characterization of GumC, an enzyme involved in the biosynthesis of exopolysaccharide by Xylella fastidiosa.

de Pieri C, Beltramini LM, Selistre-de-Araújo HS, Vettore AL, da Silva FR, Arruda P, Oliva G, de Souza DH.

Protein Expr Purif. 2004 Apr;34(2):223-8.


Overexpression, purification, biochemical characterization, and molecular modeling of recombinant GDP-mannosyltransferase (GumH) from Xylella fastidiosa.

Muniz JR, Alves CA, de Pieri C, Beltramini LM, Selistre-de-Araújo HS, Vettore AL, da Silva FR, Arruda P, Garratt RC, Oliva G, Souza DH.

Biochem Biophys Res Commun. 2004 Mar 5;315(2):485-92.


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