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Items: 1 to 20 of 219

1.

Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.

Rondelet A, Lin YC, Singh D, Porfetye AT, Thakur HC, Hecker A, Brinkert P, Schmidt N, Bendre S, Müller F, Mazul L, Widlund PO, Bange T, Hiller M, Vetter IR, Bird AW.

J Cell Biol. 2020 Feb 3;219(2). pii: e201907083. doi: 10.1083/jcb.201907083.

PMID:
31932847
2.

Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1).

Lunk I, Litty FA, Hennig S, Vetter IR, Kotthaus J, Altmann KS, Ott G, Havemeyer A, Carrillo García C, Clement B, Schade D.

J Med Chem. 2020 Jan 9;63(1):425-432. doi: 10.1021/acs.jmedchem.9b01230. Epub 2019 Dec 31.

PMID:
31841335
3.

Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel NaV1.7 Inhibition.

Tran HNT, Tran P, Deuis JR, Agwa AJ, Zhang AH, Vetter I, Schroeder CI.

Bioconjug Chem. 2020 Jan 15;31(1):64-73. doi: 10.1021/acs.bioconjchem.9b00744. Epub 2019 Dec 16.

PMID:
31790574
4.

Missiles of Mass Disruption: Composition and Glandular Origin of Venom Used as a Projectile Defensive Weapon by the Assassin Bug Platymeris rhadamanthus.

Walker AA, Robinson SD, Undheim EAB, Jin J, Han X, Fry BG, Vetter I, King GF.

Toxins (Basel). 2019 Nov 18;11(11). pii: E673. doi: 10.3390/toxins11110673.

5.

High-Throughput Fluorescence Assays for Ion Channels and GPCRs.

Vetter I, Carter D, Bassett J, Deuis JR, Tay B, Jami S, Robinson SD.

Adv Exp Med Biol. 2020;1131:27-72. doi: 10.1007/978-3-030-12457-1_3. Review.

PMID:
31646506
6.

Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain.

Shenoy PA, Kuo A, Leparc G, Hildebrandt T, Rust W, Nicholson JR, Corradini L, Vetter I, Smith MT.

Clin Exp Pharmacol Physiol. 2019 Dec;46(12):1201-1215. doi: 10.1111/1440-1681.13165. Epub 2019 Sep 15.

PMID:
31429474
7.

Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen.

Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I.

Pain. 2019 Aug;160(8):1766-1780. doi: 10.1097/j.pain.0000000000001567.

PMID:
31335646
8.

Minocycline Prevents the Development of Mechanical Allodynia in Mouse Models of Vincristine-Induced Peripheral Neuropathy.

Starobova H, Mueller A, Allavena R, Lohman RJ, Sweet MJ, Vetter I.

Front Neurosci. 2019 Jun 27;13:653. doi: 10.3389/fnins.2019.00653. eCollection 2019.

9.

Inflammatory and Neuropathic Gene Expression Signatures of Chemotherapy-Induced Neuropathy Induced by Vincristine, Cisplatin, and Oxaliplatin in C57BL/6J Mice.

Starobova H, Mueller A, Deuis JR, Carter DA, Vetter I.

J Pain. 2019 Jun 29. pii: S1526-5900(19)30751-5. doi: 10.1016/j.jpain.2019.06.008. [Epub ahead of print]

PMID:
31260808
10.

The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis.

Laraia L, Friese A, Corkery DP, Konstantinidis G, Erwin N, Hofer W, Karatas H, Klewer L, Brockmeyer A, Metz M, Schölermann B, Dwivedi M, Li L, Rios-Munoz P, Köhn M, Winter R, Vetter IR, Ziegler S, Janning P, Wu YW, Waldmann H.

Nat Chem Biol. 2019 Jul;15(7):710-720. doi: 10.1038/s41589-019-0307-5. Epub 2019 Jun 20.

PMID:
31222192
11.

NaV 1.6 regulates excitability of mechanosensitive sensory neurons.

Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I.

J Physiol. 2019 Jul;597(14):3751-3768. doi: 10.1113/JP278148. Epub 2019 May 13.

PMID:
31087362
12.

Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels.

Jin AH, Cristofori-Armstrong B, Rash LD, Román-González SA, Espinosa RA, Lewis RJ, Alewood PF, Vetter I.

Biochem Pharmacol. 2019 Jun;164:342-348. doi: 10.1016/j.bcp.2019.04.025. Epub 2019 Apr 24.

PMID:
31028742
13.

Development of a high-throughput fluorescent no-wash sodium influx assay.

Tay B, Stewart TA, Davis FM, Deuis JR, Vetter I.

PLoS One. 2019 Mar 11;14(3):e0213751. doi: 10.1371/journal.pone.0213751. eCollection 2019.

14.

Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.

Mostyn SN, Rawling T, Mohammadi S, Shimmon S, Frangos ZJ, Sarker S, Yousuf A, Vetter I, Ryan RM, Christie MJ, Vandenberg RJ.

J Med Chem. 2019 Mar 14;62(5):2466-2484. doi: 10.1021/acs.jmedchem.8b01775. Epub 2019 Feb 20.

15.

Graduate medical education scholarly activities initiatives: a systematic review and meta-analysis.

Wood W, McCollum J, Kukreja P, Vetter IL, Morgan CJ, Hossein Zadeh Maleki A, Riesenberg LA.

BMC Med Educ. 2018 Dec 22;18(1):318. doi: 10.1186/s12909-018-1407-8.

16.

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins.

Dash TS, Shafee T, Harvey PJ, Zhang C, Peigneur S, Deuis JR, Vetter I, Tytgat J, Anderson MA, Craik DJ, Durek T, Undheim EAB.

Structure. 2019 Feb 5;27(2):315-326.e7. doi: 10.1016/j.str.2018.10.022. Epub 2018 Dec 13.

PMID:
30554841
17.

Buzz Kill: Function and Proteomic Composition of Venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae).

Walker AA, Dobson J, Jin J, Robinson SD, Herzig V, Vetter I, King GF, Fry BG.

Toxins (Basel). 2018 Nov 5;10(11). pii: E456. doi: 10.3390/toxins10110456.

18.

Transcriptomics in pain research: insights from new and old technologies.

Starobova H, S W A H, Lewis RJ, Vetter I.

Mol Omics. 2018 Dec 3;14(6):389-404. doi: 10.1039/c8mo00181b. Review.

PMID:
30374497
19.

A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family.

Robinson SD, Mueller A, Clayton D, Starobova H, Hamilton BR, Payne RJ, Vetter I, King GF, Undheim EAB.

Sci Adv. 2018 Sep 12;4(9):eaau4640. doi: 10.1126/sciadv.aau4640. eCollection 2018 Sep.

20.

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides.

Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ.

Sci Rep. 2018 Sep 7;8(1):13397. doi: 10.1038/s41598-018-31245-4.

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