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Items: 19

1.

Engineered CHO cells for production of diverse, homogeneous glycoproteins.

Yang Z, Wang S, Halim A, Schulz MA, Frodin M, Rahman SH, Vester-Christensen MB, Behrens C, Kristensen C, Vakhrushev SY, Bennett EP, Wandall HH, Clausen H.

Nat Biotechnol. 2015 Aug;33(8):842-4. doi: 10.1038/nbt.3280. Epub 2015 Jul 20.

PMID:
26192319
2.

Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.

Campos D, Freitas D, Gomes J, Magalhães A, Steentoft C, Gomes C, Vester-Christensen MB, Ferreira JA, Afonso LP, Santos LL, Pinto de Sousa J, Mandel U, Clausen H, Vakhrushev SY, Reis CA.

Mol Cell Proteomics. 2015 Jun;14(6):1616-29. doi: 10.1074/mcp.M114.046862. Epub 2015 Mar 26.

3.

Crystal structure of barley limit dextrinase-limit dextrinase inhibitor (LD-LDI) complex reveals insights into mechanism and diversity of cereal type inhibitors.

Møller MS, Vester-Christensen MB, Jensen JM, Hachem MA, Henriksen A, Svensson B.

J Biol Chem. 2015 May 15;290(20):12614-29. doi: 10.1074/jbc.M115.642777. Epub 2015 Mar 19.

4.

Fast and sensitive detection of indels induced by precise gene targeting.

Yang Z, Steentoft C, Hauge C, Hansen L, Thomsen AL, Niola F, Vester-Christensen MB, Frödin M, Clausen H, Wandall HH, Bennett EP.

Nucleic Acids Res. 2015 May 19;43(9):e59. doi: 10.1093/nar/gkv126. Epub 2015 Mar 9.

5.

A glycogene mutation map for discovery of diseases of glycosylation.

Hansen L, Lind-Thomsen A, Joshi HJ, Pedersen NB, Have CT, Kong Y, Wang S, Sparso T, Grarup N, Vester-Christensen MB, Schjoldager K, Freeze HH, Hansen T, Pedersen O, Henrissat B, Mandel U, Clausen H, Wandall HH, Bennett EP.

Glycobiology. 2015 Feb;25(2):211-24. doi: 10.1093/glycob/cwu104. Epub 2014 Sep 28.

6.

Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis.

Kong Y, Joshi HJ, Schjoldager KT, Madsen TD, Gerken TA, Vester-Christensen MB, Wandall HH, Bennett EP, Levery SB, Vakhrushev SY, Clausen H.

Glycobiology. 2015 Jan;25(1):55-65. doi: 10.1093/glycob/cwu089. Epub 2014 Aug 25.

7.

Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins.

Vester-Christensen MB, Halim A, Joshi HJ, Steentoft C, Bennett EP, Levery SB, Vakhrushev SY, Clausen H.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21018-23. doi: 10.1073/pnas.1313446110. Epub 2013 Oct 7.

8.

Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing.

Madsen CB, Lavrsen K, Steentoft C, Vester-Christensen MB, Clausen H, Wandall HH, Pedersen AE.

PLoS One. 2013 Sep 6;8(9):e72413. doi: 10.1371/journal.pone.0072413. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/81b54c99-e47f-4128-8aeb-b6b3e8c02562.

9.

Generation of monoclonal antibodies to native active human glycosyltransferases.

Vester-Christensen MB, Bennett EP, Clausen H, Mandel U.

Methods Mol Biol. 2013;1022:403-20. doi: 10.1007/978-1-62703-465-4_30.

PMID:
23765678
10.

The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation.

Gerken TA, Revoredo L, Thome JJ, Tabak LA, Vester-Christensen MB, Clausen H, Gahlay GK, Jarvis DL, Johnson RW, Moniz HA, Moremen K.

J Biol Chem. 2013 Jul 5;288(27):19900-14. doi: 10.1074/jbc.M113.477877. Epub 2013 May 20.

11.

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.

Steentoft C, Vakhrushev SY, Joshi HJ, Kong Y, Vester-Christensen MB, Schjoldager KT, Lavrsen K, Dabelsteen S, Pedersen NB, Marcos-Silva L, Gupta R, Bennett EP, Mandel U, Brunak S, Wandall HH, Levery SB, Clausen H.

EMBO J. 2013 May 15;32(10):1478-88. doi: 10.1038/emboj.2013.79. Epub 2013 Apr 12.

12.

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

van der Post S, Subramani DB, Bäckström M, Johansson ME, Vester-Christensen MB, Mandel U, Bennett EP, Clausen H, Dahlén G, Sroka A, Potempa J, Hansson GC.

J Biol Chem. 2013 May 17;288(20):14636-46. doi: 10.1074/jbc.M113.459479. Epub 2013 Apr 1.

13.

Enhanced mass spectrometric mapping of the human GalNAc-type O-glycoproteome with SimpleCells.

Vakhrushev SY, Steentoft C, Vester-Christensen MB, Bennett EP, Clausen H, Levery SB.

Mol Cell Proteomics. 2013 Apr;12(4):932-44. doi: 10.1074/mcp.O112.021972. Epub 2013 Feb 11.

14.

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines.

Steentoft C, Vakhrushev SY, Vester-Christensen MB, Schjoldager KT, Kong Y, Bennett EP, Mandel U, Wandall H, Levery SB, Clausen H.

Nat Methods. 2011 Oct 9;8(11):977-82. doi: 10.1038/nmeth.1731.

PMID:
21983924
15.

A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing.

Schjoldager KT, Vester-Christensen MB, Goth CK, Petersen TN, Brunak S, Bennett EP, Levery SB, Clausen H.

J Biol Chem. 2011 Nov 18;286(46):40122-32. doi: 10.1074/jbc.M111.287912. Epub 2011 Sep 20.

16.

Efficient secretory expression of functional barley limit dextrinase inhibitor by high cell-density fermentation of Pichia pastoris.

Jensen JM, Vester-Christensen MB, Møller MS, Bønsager BC, Christensen HE, Hachem MA, Svensson B.

Protein Expr Purif. 2011 Oct;79(2):217-22. doi: 10.1016/j.pep.2011.04.009. Epub 2011 Apr 27.

PMID:
21539920
17.

Crystal structure of an essential enzyme in seed starch degradation: barley limit dextrinase in complex with cyclodextrins.

Vester-Christensen MB, Abou Hachem M, Svensson B, Henriksen A.

J Mol Biol. 2010 Nov 12;403(5):739-50. doi: 10.1016/j.jmb.2010.09.031. Epub 2010 Sep 21.

PMID:
20863834
18.

O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids.

Schjoldager KT, Vester-Christensen MB, Bennett EP, Levery SB, Schwientek T, Yin W, Blixt O, Clausen H.

J Biol Chem. 2010 Nov 19;285(47):36293-303. doi: 10.1074/jbc.M110.156950. Epub 2010 Sep 13.

19.

Secretory expression of functional barley limit dextrinase by Pichia pastoris using high cell-density fermentation.

Vester-Christensen MB, Hachem MA, Naested H, Svensson B.

Protein Expr Purif. 2010 Jan;69(1):112-9. doi: 10.1016/j.pep.2009.08.016. Epub 2009 Sep 3.

PMID:
19733243

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