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Daily volume of cases in emergency call centers: construction and validation of a predictive model.

Viglino D, Vesin A, Ruckly S, Morelli X, Slama R, Debaty G, Danel V, Maignan M, Timsit JF.

Scand J Trauma Resusc Emerg Med. 2017 Aug 29;25(1):86. doi: 10.1186/s13049-017-0430-9.


Evaluation of eight biomarkers to predict short-term mortality in patients with acute severe dyspnea.

Ara-Somohano C, Bonadona A, Carpentier F, Pavese P, Vesin A, Hamidfar-Roy R, Minet C, Vanzetto G, Schwebel C, Timsit JF.

Minerva Anestesiol. 2017 Aug;83(8):824-835. doi: 10.23736/S0375-9393.17.10882-5. Epub 2017 Mar 8.


Complications of intravascular catheters in ICU: definitions, incidence and severity. A randomized controlled trial comparing usual transparent dressings versus new-generation dressings (the ADVANCED study).

Günther SC, Schwebel C, Hamidfar-Roy R, Bonadona A, Lugosi M, Ara-Somohano C, Minet C, Potton L, Cartier JC, Vésin A, Chautemps M, Styfalova L, Ruckly S, Timsit JF.

Intensive Care Med. 2016 Nov;42(11):1753-1765. Epub 2016 Oct 12.


Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial.

Souweine B, Lautrette A, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Guelon D, Darmon M, Vesin A, Caillot N, Schwebel C, Boyer A, Azoulay E, Bouadma L, Timsit JF.

Am J Respir Crit Care Med. 2015 May 1;191(9):1024-32. doi: 10.1164/rccm.201408-1431OC.


The Iatroref study: medical errors are associated with symptoms of depression in ICU staff but not burnout or safety culture.

Garrouste-Orgeas M, Perrin M, Soufir L, Vesin A, Blot F, Maxime V, Beuret P, Troché G, Klouche K, Argaud L, Azoulay E, Timsit JF.

Intensive Care Med. 2015 Feb;41(2):273-84. doi: 10.1007/s00134-014-3601-4. Epub 2015 Jan 10.


Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study.

Toffart AC, Moro-Sibilot D, Couraud S, Merle P, Perol M, Girard N, Souquet PJ, Mastroianni B, Ferretti GR, Romand P, Chatellain P, Vesin A, Brambilla E, Brambilla C, Timsit JF.

BMC Cancer. 2014 Dec 20;14:989. doi: 10.1186/1471-2407-14-989.


Bloodstream infections in ICU with increased resistance: epidemiology and outcomes.

Dimopoulos G, Koulenti D, Tabah A, Poulakou G, Vesin A, Arvaniti K, Lathyris D, Matthaiou DK, Armaganidis A, Timsit JF.

Minerva Anestesiol. 2015 Apr;81(4):405-18. Epub 2014 Sep 15.


ICU physician-based determinants of life-sustaining therapy during nights and weekends: French multicenter study from the Outcomerea Research Group.

Garrouste-Orgeas M, Ben-Rehouma M, Darmon M, Ruckly S, Clec'h C, Adrie C, Tabah A, Vesin A, Schwebel C, Misset B, Timsit JF.

Crit Care Med. 2014 Nov;42(11):2393-400. doi: 10.1097/CCM.0000000000000523.


Initiation of nutritional support is delayed in critically ill obese patients: a multicenter cohort study.

Borel AL, Schwebel C, Planquette B, Vésin A, Garrouste-Orgeas M, Adrie C, Clec'h C, Azoulay E, Souweine B, Allaouchiche B, Goldgran-Toledano D, Jamali S, Darmon M, Timsit JF.

Am J Clin Nutr. 2014 Sep;100(3):859-66. doi: 10.3945/ajcn.114.088187. Epub 2014 Jul 30.


Sepsis severe or septic shock: outcome according to immune status and immunodeficiency profile.

Tolsma V, Schwebel C, Azoulay E, Darmon M, Souweine B, Vesin A, Goldgran-Toledano D, Lugosi M, Jamali S, Cheval C, Adrie C, Kallel H, Descorps-Declere A, Garrouste-Orgeas M, Bouadma L, Timsit JF.

Chest. 2014 Nov;146(5):1205-1213. doi: 10.1378/chest.13-2618.


Aspergillus in the lower respiratory tract of immunocompetent critically ill patients.

Lugosi M, Alberti C, Zahar JR, Garrouste M, Lemiale V, Descorps-Desclère A, Ricard JD, Goldgran-Tolédano D, Cohen Y, Schwebel C, Vésin A, Timsit JF, Azoulay E.

J Infect. 2014 Sep;69(3):284-92. doi: 10.1016/j.jinf.2014.04.010. Epub 2014 Jun 9.


Long-term adherence with non-invasive ventilation improves prognosis in obese COPD patients.

Borel JC, Pepin JL, Pison C, Vesin A, Gonzalez-Bermejo J, Court-Fortune I, Timsit JF.

Respirology. 2014 Aug;19(6):857-65. doi: 10.1111/resp.12327. Epub 2014 Jun 9.


Noninvasive mechanical ventilation in acute respiratory failure: trends in use and outcomes.

Schnell D, Timsit JF, Darmon M, Vesin A, Goldgran-Toledano D, Dumenil AS, Garrouste-Orgeas M, Adrie C, Bouadma L, Planquette B, Cohen Y, Schwebel C, Soufir L, Jamali S, Souweine B, Azoulay E.

Intensive Care Med. 2014 Apr;40(4):582-91. doi: 10.1007/s00134-014-3222-y. Epub 2014 Feb 7.


Immunohistochemistry evaluation of biomarker expression in non-small cell lung cancer (Pharmacogenoscan study).

Toffart AC, Timsit JF, Couraud S, Merle P, Moro-Sibilot D, Perol M, Mastroianni B, Souquet PJ, Girard N, Jeannin G, Romand P, Chatellain P, Vesin A, Brambilla C, Brambilla E.

Lung Cancer. 2014 Feb;83(2):182-8. doi: 10.1016/j.lungcan.2013.12.003. Epub 2013 Dec 21.


Diagnosis and management of temperature abnormality in ICUs: a EUROBACT investigators' survey.

Niven DJ, Laupland KB, Tabah A, Vesin A, Rello J, Koulenti D, Dimopoulos G, de Waele J, Timsit JF; EUROBACT Investigators.

Crit Care. 2013 Dec 10;17(6):R289. doi: 10.1186/cc13153.


EMPIRICUS micafungin versus placebo during nosocomial sepsis in Candida multi-colonized ICU patients with multiple organ failures: study protocol for a randomized controlled trial.

Timsit JF, Azoulay E, Cornet M, Gangneux JP, Jullien V, Vésin A, Schir E, Wolff M.

Trials. 2013 Nov 21;14:399. doi: 10.1186/1745-6215-14-399.


Impact of contact isolation for multidrug-resistant organisms on the occurrence of medical errors and adverse events.

Zahar JR, Garrouste-Orgeas M, Vesin A, Schwebel C, Bonadona A, Philippart F, Ara-Somohano C, Misset B, Timsit JF.

Intensive Care Med. 2013 Dec;39(12):2153-60. doi: 10.1007/s00134-013-3071-0. Epub 2013 Aug 31.


Transfluthrin indoor air concentration and inhalation exposure during application of electric vaporizers.

Vesin A, Glorennec P, Le Bot B, Wortham H, Bonvallot N, Quivet E.

Environ Int. 2013 Oct;60:1-6. doi: 10.1016/j.envint.2013.07.011. Epub 2013 Aug 23.


The ETHICA study (part II): simulation study of determinants and variability of ICU physician decisions in patients aged 80 or over.

Garrouste-Orgeas M, Tabah A, Vesin A, Philippart F, Kpodji A, Bruel C, Grégoire C, Max A, Timsit JF, Misset B.

Intensive Care Med. 2013 Sep;39(9):1574-83. doi: 10.1007/s00134-013-2977-x. Epub 2013 Jun 14.


The ETHICA study (part I): elderly's thoughts about intensive care unit admission for life-sustaining treatments.

Philippart F, Vesin A, Bruel C, Kpodji A, Durand-Gasselin B, Garçon P, Levy-Soussan M, Jagot JL, Calvo-Verjat N, Timsit JF, Misset B, Garrouste-Orgeas M.

Intensive Care Med. 2013 Sep;39(9):1565-73. doi: 10.1007/s00134-013-2976-y. Epub 2013 Jun 14.


Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers.

Rousseaux S, Debernardi A, Jacquiau B, Vitte AL, Vesin A, Nagy-Mignotte H, Moro-Sibilot D, Brichon PY, Lantuejoul S, Hainaut P, Laffaire J, de Reyniès A, Beer DG, Timsit JF, Brambilla C, Brambilla E, Khochbin S.

Sci Transl Med. 2013 May 22;5(186):186ra66. doi: 10.1126/scitranslmed.3005723.


Reporting and handling missing values in clinical studies in intensive care units.

Vesin A, Azoulay E, Ruckly S, Vignoud L, Rusinovà K, Benoit D, Soares M, Azeivedo-Maia P, Abroug F, Benbenishty J, Timsit JF.

Intensive Care Med. 2013 Aug;39(8):1396-404. doi: 10.1007/s00134-013-2949-1. Epub 2013 May 18. Review.


Pseudomonas aeruginosa ventilator-associated pneumonia. predictive factors of treatment failure.

Planquette B, Timsit JF, Misset BY, Schwebel C, Azoulay E, Adrie C, Vesin A, Jamali S, Zahar JR, Allaouchiche B, Souweine B, Darmon M, Dumenil AS, Goldgran-Toledano D, Mourvillier BH, Bédos JP; OUTCOMEREA Study Group.

Am J Respir Crit Care Med. 2013 Jul 1;188(1):69-76. doi: 10.1164/rccm.201210-1897OC.


Outcome of ICU patients with Clostridium difficile infection.

Zahar JR, Schwebel C, Adrie C, Garrouste-Orgeas M, Français A, Vesin A, Nguile-Makao M, Tabah A, Laupland K, Le-Monnier A, Timsit JF; OUTCOMEREA study group.

Crit Care. 2012 Nov 5;16(6):R215. doi: 10.1186/cc11852.


Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults.

Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Lepape A, Vesin A, Arrault X, Schwebel C, Adrie C, Zahar JR, Ruckly S, Tournegros C, Lucet JC.

Am J Respir Crit Care Med. 2012 Dec 15;186(12):1272-8. doi: 10.1164/rccm.201206-1038OC. Epub 2012 Oct 4.


Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study.

Tabah A, Koulenti D, Laupland K, Misset B, Valles J, Bruzzi de Carvalho F, Paiva JA, Cakar N, Ma X, Eggimann P, Antonelli M, Bonten MJ, Csomos A, Krueger WA, Mikstacki A, Lipman J, Depuydt P, Vesin A, Garrouste-Orgeas M, Zahar JR, Blot S, Carlet J, Brun-Buisson C, Martin C, Rello J, Dimopoulos G, Timsit JF.

Intensive Care Med. 2012 Dec;38(12):1930-45. doi: 10.1007/s00134-012-2695-9. Epub 2012 Sep 26.


Outcomes in recurrent small-cell lung cancer after one to four chemotherapy lines: a retrospective study of 300 patients.

Nagy-Mignotte H, Guillem P, Vignoud L, Coudurier M, Vesin A, Bonneterre V, Toffart AC, Sakhri L, Brambilla C, Brambilla E, Timsit JF, Moro-Sibilot D; Multidisciplinary Thoracic Oncology Group.

Lung Cancer. 2012 Oct;78(1):112-20. doi: 10.1016/j.lungcan.2012.06.006. Epub 2012 Jul 12.


Impact of an intensive care unit diary on psychological distress in patients and relatives*.

Garrouste-Orgeas M, Coquet I, Périer A, Timsit JF, Pochard F, Lancrin F, Philippart F, Vesin A, Bruel C, Blel Y, Angeli S, Cousin N, Carlet J, Misset B.

Crit Care Med. 2012 Jul;40(7):2033-40. doi: 10.1097/CCM.0b013e31824e1b43.


Use of the HS-PTR-MS for online measurements of pyrethroids during indoor insecticide treatments.

Vesin A, Bouchoux G, Quivet E, Temime-Roussel B, Wortham H.

Anal Bioanal Chem. 2012 Jun;403(7):1907-21. doi: 10.1007/s00216-012-6003-x. Epub 2012 Apr 27.


Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.

Pajares MJ, Agorreta J, Larrayoz M, Vesin A, Ezponda T, Zudaire I, Torre W, Lozano MD, Brambilla E, Brambilla C, Wistuba II, Behrens C, Timsit JF, Pio R, Field JK, Montuenga LM.

J Clin Oncol. 2012 Apr 1;30(10):1129-36. doi: 10.1200/JCO.2011.37.4231. Epub 2012 Feb 21.


Increased nonbeneficial care in patients spending their birthday in the ICU.

Azoulay E, Garrouste M, Goldgran-Toledano D, Adrie C, Max A, Vesin A, Francais A, Zahar JR, Cohen Y, Allaouchiche B, Schlemmer B, Timsit JF.

Intensive Care Med. 2012 Jul;38(7):1169-76. doi: 10.1007/s00134-012-2510-7. Epub 2012 Feb 10.


Severe hypothermia increases the risk for intensive care unit-acquired infection.

Laupland KB, Zahar JR, Adrie C, Minet C, Vésin A, Goldgran-Toledano D, Azoulay E, Garrouste-Orgeas M, Cohen Y, Schwebel C, Jamali S, Darmon M, Dumenil AS, Kallel H, Souweine B, Timsit JF.

Clin Infect Dis. 2012 Apr;54(8):1064-70. doi: 10.1093/cid/cir1033. Epub 2012 Jan 30.


Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort.

Scoccianti C, Vesin A, Martel G, Olivier M, Brambilla E, Timsit JF, Tavecchio L, Brambilla C, Field JK, Hainaut P; European Early Lung Cancer Consortium.

Eur Respir J. 2012 Jul;40(1):177-84. doi: 10.1183/09031936.00097311. Epub 2012 Jan 20.


A model to predict short-term death or readmission after intensive care unit discharge.

Ouanes I, Schwebel C, Français A, Bruel C, Philippart F, Vesin A, Soufir L, Adrie C, Garrouste-Orgeas M, Timsit JF, Misset B; Outcomerea Study Group.

J Crit Care. 2012 Aug;27(4):422.e1-9. doi: 10.1016/j.jcrc.2011.08.003. Epub 2011 Dec 14.


Endovascular treatment of malignant superior vena cava syndrome: results and predictive factors of clinical efficacy.

Fagedet D, Thony F, Timsit JF, Rodiere M, Monnin-Bares V, Ferretti GR, Vesin A, Moro-Sibilot D.

Cardiovasc Intervent Radiol. 2013 Feb;36(1):140-9. doi: 10.1007/s00270-011-0310-z. Epub 2011 Dec 7.


Mortality associated with timing of admission to and discharge from ICU: a retrospective cohort study.

Laupland KB, Misset B, Souweine B, Tabah A, Azoulay E, Goldgran-Toledano D, Dumenil AS, Vésin A, Jamali S, Kallel H, Clec'h C, Darmon M, Schwebel C, Timsit JF.

BMC Health Serv Res. 2011 Nov 24;11:321. doi: 10.1186/1472-6963-11-321.


Antifungal use influences Candida species distribution and susceptibility in the intensive care unit.

Fournier P, Schwebel C, Maubon D, Vesin A, Lebeau B, Foroni L, Hamidfar-Roy R, Cornet M, Timsit JF, Pelloux H.

J Antimicrob Chemother. 2011 Dec;66(12):2880-6. doi: 10.1093/jac/dkr394. Epub 2011 Oct 6.


A multifaceted program for improving quality of care in intensive care units: IATROREF study.

Garrouste-Orgeas M, Soufir L, Tabah A, Schwebel C, Vesin A, Adrie C, Thuong M, Timsit JF; Outcomerea Study Group.

Crit Care Med. 2012 Feb;40(2):468-76. doi: 10.1097/CCM.0b013e318232d94d.


Economic evaluation of chlorhexidine-impregnated sponges for preventing catheter-related infections in critically ill adults in the Dressing Study.

Schwebel C, Lucet JC, Vesin A, Arrault X, Calvino-Gunther S, Bouadma L, Timsit JF.

Crit Care Med. 2012 Jan;40(1):11-7. doi: 10.1097/CCM.0b013e31822f0604.


Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis.

Bekaert M, Timsit JF, Vansteelandt S, Depuydt P, Vésin A, Garrouste-Orgeas M, Decruyenaere J, Clec'h C, Azoulay E, Benoit D; Outcomerea Study Group.

Am J Respir Crit Care Med. 2011 Nov 15;184(10):1133-9. doi: 10.1164/rccm.201105-0867OC.


Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development.

Thunnissen FB, Prinsen C, Hol B, Van der Drift M, Vesin A, Brambilla C, Montuenga L, Field JK; EUELC consortium.

Lung Cancer. 2012 Feb;75(2):156-60. doi: 10.1016/j.lungcan.2011.07.013. Epub 2011 Aug 11.


Primary lung adenocarcinoma: characteristics by smoking habit and sex.

Nagy-Mignotte H, Guillem P, Vesin A, Toffart AC, Colonna M, Bonneterre V, Brichon PY, Brambilla C, Brambilla E, Lantuejoul S, Timsit JF, Moro-Sibilot D; Multidisciplinary Thoracic Oncology Group at Grenoble University Hospital.

Eur Respir J. 2011 Dec;38(6):1412-9. doi: 10.1183/09031936.00191710. Epub 2011 Aug 4.


Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality.

Zahar JR, Timsit JF, Garrouste-Orgeas M, Français A, Vesin A, Descorps-Declere A, Dubois Y, Souweine B, Haouache H, Goldgran-Toledano D, Allaouchiche B, Azoulay E, Adrie C.

Crit Care Med. 2011 Aug;39(8):1886-95. doi: 10.1097/CCM.0b013e31821b827c. Erratum in: Crit Care Med. 2011 Oct;39(10):2392. Vesim, Aurélien [corrected to Vesin, Aurélien].


Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa.

Kaminski C, Timsit JF, Dubois Y, Zahar JR, Garrouste-Orgeas M, Vesin A, Azoulay E, Feger C, Dumenil AS, Adrie C, Cohen Y, Allaouchiche B; OUTCOMEREA study group.

Crit Care. 2011;15(2):R112. doi: 10.1186/cc10136. Epub 2011 Apr 11.


Identifying adult asthma phenotypes using a clustering approach.

Siroux V, Basagaña X, Boudier A, Pin I, Garcia-Aymerich J, Vesin A, Slama R, Jarvis D, Anto JM, Kauffmann F, Sunyer J.

Eur Respir J. 2011 Aug;38(2):310-7. doi: 10.1183/09031936.00120810. Epub 2011 Jan 13.


Therapeutic impact and diagnostic performance of multiplex PCR in patients with malignancies and suspected sepsis.

Maubon D, Hamidfar-Roy R, Courby S, Vesin A, Maurin M, Pavese P, Ravanel N, Bulabois CE, Brion JP, Pelloux H, Timsit JF.

J Infect. 2010 Oct;61(4):335-42. doi: 10.1016/j.jinf.2010.07.004. Epub 2010 Jul 15.


Prognostic value of hTERT mRNA expression in surgical samples of lung cancer patients: the European Early Lung Cancer Project.

Van den Berg RM, Brokx H, Vesin A, Field JK, Brambilla C, Meijer CJ, Sutedja GT, Heideman DA, Postmus PE, Smit EF, Snijders PJ.

Int J Oncol. 2010 Aug;37(2):455-61.


Opinions of families, staff, and patients about family participation in care in intensive care units.

Garrouste-Orgeas M, Willems V, Timsit JF, Diaw F, Brochon S, Vesin A, Philippart F, Tabah A, Coquet I, Bruel C, Moulard ML, Carlet J, Misset B.

J Crit Care. 2010 Dec;25(4):634-40. doi: 10.1016/j.jcrc.2010.03.001.


Expression of candidate tumor suppressor gene ING2 is lost in non-small cell lung carcinoma.

Ythier D, Brambilla E, Binet R, Nissou D, Vesin A, de Fraipont F, Moro-Sibilot D, Lantuejoul S, Brambilla C, Gazzeri S, Pedeux R.

Lung Cancer. 2010 Aug;69(2):180-6. doi: 10.1016/j.lungcan.2009.11.006. Epub 2009 Dec 4.


EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration.

Field JK, Liloglou T, Niaz A, Bryan J, Gosney JR, Giles T, Brambilla C, Brambilla E, Vesin A, Timsit JF, Hainaut P, Martinet Y, Vignaud JM, Thunnissen FB, Prinsen C, Snijders PJ, Smit EF, Sozzi G, Roz L, Risch A, Becker HD, Elborn JS, Magee ND, Montuenga LM, Pajares MJ, Lozano MD, O'Byrne KJ, Harrison DJ, Niklinski J, Cassidy A; EUELC Collaborators.

Eur Respir J. 2009 Dec;34(6):1477-86. doi: 10.1183/09031936.00077809.

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