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Items: 1 to 50 of 106

1.

Production and characterization of human induced pluripotent stem cells (iPSC) CSSi007-A (4383) from Joubert Syndrome.

Altieri F, D'Anzi A, Martello F, Tardivo S, Spasari I, Ferrari D, Bernardini L, Lamorte G, Mazzoccoli G, Valente EM, Vescovi AL, Rosati J.

Stem Cell Res. 2019 Jun 5;38:101480. doi: 10.1016/j.scr.2019.101480. [Epub ahead of print]

2.

Parkin Mutation Affects Clock Gene-Dependent Energy Metabolism.

Pacelli C, Rotundo G, Lecce L, Menga M, Bidollari E, Scrima R, Cela O, Piccoli C, Cocco T, Vescovi AL, Mazzoccoli G, Rosati J, Capitanio N.

Int J Mol Sci. 2019 Jun 5;20(11). pii: E2772. doi: 10.3390/ijms20112772.

3.

Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome.

Mazzini L, Gelati M, Profico DC, Sorarù G, Ferrari D, Copetti M, Muzi G, Ricciolini C, Carletti S, Giorgi C, Spera C, Frondizi D, Masiero S, Stecco A, Cisari C, Bersano E, De Marchi F, Sarnelli MF, Querin G, Cantello R, Petruzzelli F, Maglione A, Zalfa C, Binda E, Visioli A, Trombetta D, Torres B, Bernardini L, Gaiani A, Massara M, Paolucci S, Boulis NM, Vescovi AL; ALS-NSCs Trial Study Group.

Stem Cells Transl Med. 2019 May 18. doi: 10.1002/sctm.18-0154. [Epub ahead of print]

4.

Stemness underpinning all steps of human colorectal cancer defines the core of effective therapeutic strategies.

Visioli A, Giani F, Trivieri N, Pracella R, Miccinilli E, Cariglia MG, Palumbo O, Arleo A, Dezi F, Copetti M, Cajola L, Restelli S, Papa V, Sciuto A, Latiano TP, Carella M, Amadori D, Gallerani G, Ricci R, Alfieri S, Pesole G, Vescovi AL, Binda E.

EBioMedicine. 2019 May 2. pii: S2352-3964(19)30288-9. doi: 10.1016/j.ebiom.2019.04.049. [Epub ahead of print]

5.

Transplantation of clinical-grade human neural stem cells reduces neuroinflammation, prolongs survival and delays disease progression in the SOD1 rats.

Zalfa C, Rota Nodari L, Vacchi E, Gelati M, Profico D, Boido M, Binda E, De Filippis L, Copetti M, Garlatti V, Daniele P, Rosati J, De Luca A, Pinos F, Cajola L, Visioli A, Mazzini L, Vercelli A, Svelto M, Vescovi AL, Ferrari D.

Cell Death Dis. 2019 Apr 25;10(5):345. doi: 10.1038/s41419-019-1582-5.

6.

Multifunctionalized hydrogels foster hNSC maturation in 3D cultures and neural regeneration in spinal cord injuries.

Marchini A, Raspa A, Pugliese R, El Malek MA, Pastori V, Lecchi M, Vescovi AL, Gelain F.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7483-7492. doi: 10.1073/pnas.1818392116. Epub 2019 Mar 28.

7.

AQP4 Aggregation State Is a Determinant for Glioma Cell Fate.

Simone L, Pisani F, Mola MG, De Bellis M, Merla G, Micale L, Frigeri A, Vescovi AL, Svelto M, Nicchia GP.

Cancer Res. 2019 May 1;79(9):2182-2194. doi: 10.1158/0008-5472.CAN-18-2015. Epub 2019 Mar 15.

PMID:
30877104
8.

Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma.

Mastrella G, Hou M, Li M, Stoecklein VM, Zdouc N, Volmar MNM, Miletic H, Reinhard S, Herold-Mende CC, Kleber S, Eisenhut K, Gargiulo G, Synowitz M, Vescovi AL, Harter PN, Penninger JM, Wagner E, Mittelbronn M, Bjerkvig R, Hambardzumyan D, Schüller U, Tonn JC, Radke J, Glass R, Kälin RE.

Cancer Res. 2019 May 1;79(9):2298-2313. doi: 10.1158/0008-5472.CAN-18-0881. Epub 2019 Feb 4.

PMID:
30718358
9.

EphB2 stem-related and EphA2 progression-related miRNA-based networks in progressive stages of CRC evolution: clinical significance and potential miRNA drivers.

De Robertis M, Mazza T, Fusilli C, Loiacono L, Poeta ML, Sanchez M, Massi E, Lamorte G, Diodoro MG, Pescarmona E, Signori E, Pesole G, Vescovi AL, Garcia-Foncillas J, Fazio VM.

Mol Cancer. 2018 Nov 30;17(1):169. doi: 10.1186/s12943-018-0912-z.

10.

Drug Delivery in an Orthotopic Tumor Stem Cell-Based Model of Human Glioblastoma.

Binda E, Visioli A, Trivieri N, Vescovi AL.

Methods Mol Biol. 2019;1869:197-205. doi: 10.1007/978-1-4939-8805-1_17.

PMID:
30324525
11.

Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies.

Rosati J, Ferrari D, Altieri F, Tardivo S, Ricciolini C, Fusilli C, Zalfa C, Profico DC, Pinos F, Bernardini L, Torres B, Manni I, Piaggio G, Binda E, Copetti M, Lamorte G, Mazza T, Carella M, Gelati M, Valente EM, Simeone A, Vescovi AL.

Cell Death Dis. 2018 Sep 17;9(10):937. doi: 10.1038/s41419-018-0990-2.

12.

Copy number variations in healthy subjects. Case study: iPSC line CSSi005-A (3544) production from an individual with variation in 15q13.3 chromosome duplicating gene CHRNA7.

Turco EM, Vinci E, Altieri F, Ferrari D, Torres B, Goldoni M, Lamorte G, Tata AM, Mazzoccoli G, Postorivo D, Della Monica M, Bernardini L, Vescovi AL, Rosati J.

Stem Cell Res. 2018 Oct;32:73-77. doi: 10.1016/j.scr.2018.09.002. Epub 2018 Sep 6.

13.

Human Fetal Neural Stem Cells for Neurodegenerative Disease Treatment.

Ferrari D, Gelati M, Profico DC, Vescovi AL.

Results Probl Cell Differ. 2018;66:307-329. doi: 10.1007/978-3-319-93485-3_14.

PMID:
30209666
14.

Advances in stem cell therapy for amyotrophic lateral sclerosis.

Mazzini L, Ferrari D, Andjus PR, Buzanska L, Cantello R, De Marchi F, Gelati M, Giniatullin R, Glover JC, Grilli M, Kozlova EN, Maioli M, Mitrečić D, Pivoriunas A, Sanchez-Pernaute R, Sarnowska A, Vescovi AL; BIONECA COST ACTION WG Neurology.

Expert Opin Biol Ther. 2018 Aug;18(8):865-881. doi: 10.1080/14712598.2018.1503248. Review.

PMID:
30025485
15.

Cancer stem cells from peritumoral tissue of glioblastoma multiforme: the possible missing link between tumor development and progression.

Angelucci C, D'Alessio A, Lama G, Binda E, Mangiola A, Vescovi AL, Proietti G, Masuelli L, Bei R, Fazi B, Ciafrè SA, Sica G.

Oncotarget. 2018 Jun 15;9(46):28116-28130. doi: 10.18632/oncotarget.25565. eCollection 2018 Jun 15.

16.

Generation of the induced pluripotent stem cell line CSSi006-A (3681) from a patient affected by advanced-stage Juvenile Onset Huntington's Disease.

Rotundo G, Bidollari E, Ferrari D, Spasari I, Bernardini L, Consoli F, De Luca A, Santimone I, Lamorte G, Migliore S, Squitieri F, Vescovi AL, Rosati J.

Stem Cell Res. 2018 May;29:174-178. doi: 10.1016/j.scr.2018.04.008. Epub 2018 Apr 21.

17.

Production and characterization of CSSI003 (2961) human induced pluripotent stem cells (iPSCs) carrying a novel puntiform mutation in RAI1 gene, Causative of Smith-Magenis syndrome.

Altieri F, Turco EM, Vinci E, Torres B, Ferrari D, De Jaco A, Mazzoccoli G, Lamorte G, Nardone A, Della Monica M, Bernardini L, Vescovi AL, Rosati J.

Stem Cell Res. 2018 Apr;28:153-156. doi: 10.1016/j.scr.2018.02.016. Epub 2018 Feb 21.

18.

Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage.

Bidollari E, Rotundo G, Ferrari D, Candido O, Bernardini L, Consoli F, De Luca A, Santimone I, Lamorte G, Ilari A, Squitieri F, Vescovi AL, Rosati J.

Stem Cell Res. 2018 Apr;28:145-148. doi: 10.1016/j.scr.2018.02.014. Epub 2018 Feb 21.

19.

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation.

Grasselli C, Ferrari D, Zalfa C, Soncini M, Mazzoccoli G, Facchini FA, Marongiu L, Granucci F, Copetti M, Vescovi AL, Peri F, De Filippis L.

Cell Death Dis. 2018 Feb 15;9(3):280. doi: 10.1038/s41419-017-0139-8.

20.

Generation of induced pluripotent stem cell line, CSSi002-A (2851), from a patient with juvenile Huntington Disease.

Rosati J, Bidollari E, Rotundo G, Ferrari D, Torres B, Bernardini L, Consoli F, De Luca A, Santimone I, Lamorte G, Squitieri F, Vescovi AL.

Stem Cell Res. 2018 Mar;27:86-89. doi: 10.1016/j.scr.2018.01.011. Epub 2018 Jan 9.

21.

Production and characterization of human induced pluripotent stem cells (iPSCs) from Joubert Syndrome: CSSi001-A (2850).

Rosati J, Altieri F, Tardivo S, Turco EM, Goldoni M, Spasari I, Ferrari D, Bernardini L, Lamorte G, Valente EM, Vescovi AL.

Stem Cell Res. 2018 Mar;27:74-77. doi: 10.1016/j.scr.2018.01.012. Epub 2018 Jan 9.

22.

Decreased Rhes mRNA levels in the brain of patients with Parkinson's disease and MPTP-treated macaques.

Napolitano F, Booth Warren E, Migliarini S, Punzo D, Errico F, Li Q, Thiolat ML, Vescovi AL, Calabresi P, Bezard E, Morelli M, Konradi C, Pasqualetti M, Usiello A.

PLoS One. 2017 Jul 25;12(7):e0181677. doi: 10.1371/journal.pone.0181677. eCollection 2017.

23.

Extracellular vesicles are independent metabolic units with asparaginase activity.

Iraci N, Gaude E, Leonardi T, Costa ASH, Cossetti C, Peruzzotti-Jametti L, Bernstock JD, Saini HK, Gelati M, Vescovi AL, Bastos C, Faria N, Occhipinti LG, Enright AJ, Frezza C, Pluchino S.

Nat Chem Biol. 2017 Sep;13(9):951-955. doi: 10.1038/nchembio.2422. Epub 2017 Jul 3.

24.

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE.

Castellana S, Fusilli C, Mazzoccoli G, Biagini T, Capocefalo D, Carella M, Vescovi AL, Mazza T.

PLoS Comput Biol. 2017 Jun 22;13(6):e1005628. doi: 10.1371/journal.pcbi.1005628. eCollection 2017 Jun.

25.

Molecular dynamics recipes for genome research.

Biagini T, Chillemi G, Mazzoccoli G, Grottesi A, Fusilli C, Capocefalo D, Castellana S, Vescovi AL, Mazza T.

Brief Bioinform. 2018 Sep 28;19(5):853-862. doi: 10.1093/bib/bbx006.

PMID:
28334084
26.

Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells.

Binda E, Visioli A, Giani F, Trivieri N, Palumbo O, Restelli S, Dezi F, Mazza T, Fusilli C, Legnani F, Carella M, Di Meco F, Duggal R, Vescovi AL.

Cancer Res. 2017 Feb 15;77(4):996-1007. doi: 10.1158/0008-5472.CAN-16-1693. Epub 2016 Dec 23. Erratum in: Cancer Res. 2017 Jul 15;77(14 ):3962.

27.

Glial degeneration with oxidative damage drives neuronal demise in MPSII disease.

Zalfa C, Verpelli C, D'Avanzo F, Tomanin R, Vicidomini C, Cajola L, Manara R, Sala C, Scarpa M, Vescovi AL, De Filippis L.

Cell Death Dis. 2016 Aug 11;7(8):e2331. doi: 10.1038/cddis.2016.231.

28.

Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer.

De Robertis M, Loiacono L, Fusilli C, Poeta ML, Mazza T, Sanchez M, Marchionni L, Signori E, Lamorte G, Vescovi AL, Garcia-Foncillas J, Fazio VM.

Clin Cancer Res. 2017 Jan 1;23(1):159-170. doi: 10.1158/1078-0432.CCR-16-0709. Epub 2016 Jul 11.

29.

Human neural stem cell transplantation in ALS: initial results from a phase I trial.

Mazzini L, Gelati M, Profico DC, Sgaravizzi G, Projetti Pensi M, Muzi G, Ricciolini C, Rota Nodari L, Carletti S, Giorgi C, Spera C, Domenico F, Bersano E, Petruzzelli F, Cisari C, Maglione A, Sarnelli MF, Stecco A, Querin G, Masiero S, Cantello R, Ferrari D, Zalfa C, Binda E, Visioli A, Trombetta D, Novelli A, Torres B, Bernardini L, Carriero A, Prandi P, Servo S, Cerino A, Cima V, Gaiani A, Nasuelli N, Massara M, Glass J, Sorarù G, Boulis NM, Vescovi AL.

J Transl Med. 2015 Jan 27;13:17. doi: 10.1186/s12967-014-0371-2.

30.

d-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain.

Cristino L, Luongo L, Squillace M, Paolone G, Mango D, Piccinin S, Zianni E, Imperatore R, Iannotta M, Longo F, Errico F, Vescovi AL, Morari M, Maione S, Gardoni F, Nisticò R, Usiello A.

Neurobiol Aging. 2015 May;36(5):1890-902. doi: 10.1016/j.neurobiolaging.2015.02.003. Epub 2015 Feb 12.

PMID:
25771393
31.

Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release.

Cuadrado E, Michailidou I, van Bodegraven EJ, Jansen MH, Sluijs JA, Geerts D, Couraud PO, De Filippis L, Vescovi AL, Kuijpers TW, Hol EM.

J Immunol. 2015 Apr 15;194(8):3623-33. doi: 10.4049/jimmunol.1401334. Epub 2015 Mar 13.

32.

PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment.

Cenciarelli C, Marei HE, Zonfrillo M, Pierimarchi P, Paldino E, Casalbore P, Felsani A, Vescovi AL, Maira G, Mangiola A.

Mol Cancer. 2014 Nov 8;13:247. doi: 10.1186/1476-4598-13-247.

33.

Glioma stem cells: turpis omen in nomen? (The evil in the name?).

Binda E, Reynolds BA, Vescovi AL.

J Intern Med. 2014 Jul;276(1):25-40. doi: 10.1111/joim.12254. Review.

34.

Murine neural stem cells model Hunter disease in vitro: glial cell-mediated neurodegeneration as a possible mechanism involved.

Fusar Poli E, Zalfa C, D'Avanzo F, Tomanin R, Carlessi L, Bossi M, Nodari LR, Binda E, Marmiroli P, Scarpa M, Delia D, Vescovi AL, De Filippis L.

Cell Death Dis. 2013 Nov 7;4:e906. doi: 10.1038/cddis.2013.430.

35.

Culturing and expansion of "clinical grade" precursors cells from the fetal human central nervous system.

Gelati M, Profico D, Projetti-Pensi M, Muzi G, Sgaravizzi G, Vescovi AL.

Methods Mol Biol. 2013;1059:65-77. doi: 10.1007/978-1-62703-574-3_6.

PMID:
23934834
36.

Vaccinia virus expressing bone morphogenetic protein-4 in novel glioblastoma orthotopic models facilitates enhanced tumor regression and long-term survival.

Duggal R, Geissinger U, Zhang Q, Aguilar J, Chen NG, Binda E, Vescovi AL, Szalay AA.

J Transl Med. 2013 Jun 24;11:155. doi: 10.1186/1479-5876-11-155.

37.

Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome.

Cuadrado E, Jansen MH, Anink J, De Filippis L, Vescovi AL, Watts C, Aronica E, Hol EM, Kuijpers TW.

Brain. 2013 Jan;136(Pt 1):245-58. doi: 10.1093/brain/aws321.

PMID:
23365100
38.

The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas.

Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Pasquale EB, Vescovi AL.

Cancer Cell. 2012 Dec 11;22(6):765-80. doi: 10.1016/j.ccr.2012.11.005.

39.

Heterogeneity of cancer-initiating cells within glioblastoma.

Binda E, Visioli A, Reynolds B, Vescovi AL.

Front Biosci (Schol Ed). 2012 Jun 1;4:1235-48. Review.

PMID:
22652868
40.

CD90 is identified as a candidate marker for cancer stem cells in primary high-grade gliomas using tissue microarrays.

He J, Liu Y, Zhu T, Zhu J, Dimeco F, Vescovi AL, Heth JA, Muraszko KM, Fan X, Lubman DM.

Mol Cell Proteomics. 2012 Jun;11(6):M111.010744. doi: 10.1074/mcp.M111.010744. Epub 2011 Dec 27.

41.

Differential pathotropism of non-immortalized and immortalized human neural stem cell lines in a focal demyelination model.

Ferrari D, Zalfa C, Nodari LR, Gelati M, Carlessi L, Delia D, Vescovi AL, De Filippis L.

Cell Mol Life Sci. 2012 Apr;69(7):1193-210. doi: 10.1007/s00018-011-0873-5. Epub 2011 Nov 11.

PMID:
22076651
42.

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain.

van den Berge SA, van Strien ME, Korecka JA, Dijkstra AA, Sluijs JA, Kooijman L, Eggers R, De Filippis L, Vescovi AL, Verhaagen J, van de Berg WD, Hol EM.

Brain. 2011 Nov;134(Pt 11):3249-63. doi: 10.1093/brain/awr256.

PMID:
22075520
43.

Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells.

Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, Hamm LL, He X, Hervey-Jumper SL, Heth JA, Muraszko KM, DiMeco F, Vescovi AL, Fan X.

Cancer Res. 2011 Sep 15;71(18):6061-72. doi: 10.1158/0008-5472.CAN-10-4269. Epub 2011 Jul 25.

44.

Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells.

Ying M, Sang Y, Li Y, Guerrero-Cazares H, Quinones-Hinojosa A, Vescovi AL, Eberhart CG, Xia S, Laterra J.

Stem Cells. 2011 Jan;29(1):20-31. doi: 10.1002/stem.561.

45.

Long-term survival of human neural stem cells in the ischemic rat brain upon transient immunosuppression.

Rota Nodari L, Ferrari D, Giani F, Bossi M, Rodriguez-Menendez V, Tredici G, Delia D, Vescovi AL, De Filippis L.

PLoS One. 2010 Nov 19;5(11):e14035. doi: 10.1371/journal.pone.0014035.

46.

Glycoproteomic analysis of glioblastoma stem cell differentiation.

He J, Liu Y, Zhu TS, Xie X, Costello MA, Talsma CE, Flack CG, Crowley JG, Dimeco F, Vescovi AL, Fan X, Lubman DM.

J Proteome Res. 2011 Jan 7;10(1):330-8. doi: 10.1021/pr101158p. Epub 2010 Dec 16.

47.

Isolation of neural stem cells from neural tissues using the neurosphere technique.

Ferrari D, Binda E, De Filippis L, Vescovi AL.

Curr Protoc Stem Cell Biol. 2010 Nov;Chapter 2:Unit2D.6. doi: 10.1002/9780470151808.sc02d06s15.

PMID:
21049474
48.

Robust generation of oligodendrocyte progenitors from human neural stem cells and engraftment in experimental demyelination models in mice.

Neri M, Maderna C, Ferrari D, Cavazzin C, Vescovi AL, Gritti A.

PLoS One. 2010 Apr 12;5(4):e10145. doi: 10.1371/journal.pone.0010145.

49.

Identification of cell surface glycoprotein markers for glioblastoma-derived stem-like cells using a lectin microarray and LC-MS/MS approach.

He J, Liu Y, Xie X, Zhu T, Soules M, DiMeco F, Vescovi AL, Fan X, Lubman DM.

J Proteome Res. 2010 May 7;9(5):2565-72. doi: 10.1021/pr100012p.

50.

Mild hypoxia enhances proliferation and multipotency of human neural stem cells.

Santilli G, Lamorte G, Carlessi L, Ferrari D, Rota Nodari L, Binda E, Delia D, Vescovi AL, De Filippis L.

PLoS One. 2010 Jan 5;5(1):e8575. doi: 10.1371/journal.pone.0008575.

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