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Items: 1 to 50 of 127

1.

The Human Ovary and Future of Fertility Assessment in the Post-Genome Era.

Ouni E, Vertommen D, Amorim CA.

Int J Mol Sci. 2019 Aug 28;20(17). pii: E4209. doi: 10.3390/ijms20174209. Review.

2.

Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility.

Yang D, Vandenbussche G, Vertommen D, Evrard D, Abskharon R, Cavalier JF, Berger G, Canaan S, Khan MS, Zeng S, Wohlkönig A, Prévost M, Soumillion P, Fontaine V.

FEBS Lett. 2019 Aug 7. doi: 10.1002/1873-3468.13555. [Epub ahead of print]

PMID:
31388991
3.

HOXA2 activity regulation by cytoplasmic relocation, protein stabilization and post-translational modification.

Deneyer N, Bridoux L, Bombled C, Pringels T, Bergiers I, Pyr Dit Ruys S, Vertommen D, Twizere JC, Rezsohazy R.

Biochim Biophys Acta Gene Regul Mech. 2019 Sep;1862(9):194404. doi: 10.1016/j.bbagrm.2019.07.005. Epub 2019 Jul 16.

PMID:
31323436
4.

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.

Pecquet C, Chachoua I, Roy A, Balligand T, Vertenoeil G, Leroy E, Albu RI, Defour JP, Nivarthi H, Hug E, Xu E, Ould-Amer Y, Mouton C, Colau D, Vertommen D, Shwe MM, Marty C, Plo I, Vainchenker W, Kralovics R, Constantinescu SN.

Blood. 2019 Jun 20;133(25):2669-2681. doi: 10.1182/blood-2018-09-874578. Epub 2019 Mar 22.

PMID:
30902807
5.

Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation.

Spillier Q, Vertommen D, Ravez S, Marteau R, Thémans Q, Corbet C, Feron O, Wouters J, Frédérick R.

Sci Rep. 2019 Mar 18;9(1):4737. doi: 10.1038/s41598-019-41187-0.

6.

Genetic deletion of soluble 5'-nucleotidase II reduces body weight gain and insulin resistance induced by a high-fat diet.

Johanns M, Kviklyte S, Chuang SJ, Corbeels K, Jacobs R, Herinckx G, Vertommen D, Schakman O, Duparc T, Cani PD, Bouzin C, Andersén H, Bohlooly-Y M, Van der Schueren B, Oscarsson J, Rider MH.

Mol Genet Metab. 2019 Apr;126(4):377-387. doi: 10.1016/j.ymgme.2019.01.017. Epub 2019 Feb 14.

PMID:
30803894
7.

Bifunctional Chloroplastic DJ-1B from Arabidopsis thaliana is an Oxidation-Robust Holdase and a Glyoxalase Sensitive to H₂O₂.

Lewandowska A, Vo TN, Nguyen TH, Wahni K, Vertommen D, Van Breusegem F, Young D, Messens J.

Antioxidants (Basel). 2019 Jan 1;8(1). pii: E8. doi: 10.3390/antiox8010008.

8.

SETD3 protein is the actin-specific histidine N-methyltransferase.

Kwiatkowski S, Seliga AK, Vertommen D, Terreri M, Ishikawa T, Grabowska I, Tiebe M, Teleman AA, Jagielski AK, Veiga-da-Cunha M, Drozak J.

Elife. 2018 Dec 11;7. pii: e37921. doi: 10.7554/eLife.37921.

9.

The Chaperone and Redox Properties of CnoX Chaperedoxins Are Tailored to the Proteostatic Needs of Bacterial Species.

Goemans CV, Beaufay F, Arts IS, Agrebi R, Vertommen D, Collet JF.

MBio. 2018 Nov 27;9(6). pii: e01541-18. doi: 10.1128/mBio.01541-18.

10.

NAT6 acetylates the N-terminus of different forms of actin.

Wiame E, Tahay G, Tyteca D, Vertommen D, Stroobant V, Bommer GT, Van Schaftingen E.

FEBS J. 2018 Sep;285(17):3299-3316. doi: 10.1111/febs.14605. Epub 2018 Aug 13.

11.

Extracellular vesicles from endothelial progenitor cells promote thyroid follicle formation.

Degosserie J, Heymans C, Spourquet C, Halbout M, D'Auria L, Van Der Smissen P, Vertommen D, Courtoy PJ, Tyteca D, Pierreux CE.

J Extracell Vesicles. 2018 Jun 28;7(1):1487250. doi: 10.1080/20013078.2018.1487250. eCollection 2018.

12.

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections.

Pinto Torres JE, Goossens J, Ding J, Li Z, Lu S, Vertommen D, Naniima P, Chen R, Muyldermans S, Sterckx YG, Magez S.

Sci Rep. 2018 Jun 13;8(1):9019. doi: 10.1038/s41598-018-26732-7.

13.

CnoX Is a Chaperedoxin: A Holdase that Protects Its Substrates from Irreversible Oxidation.

Goemans CV, Vertommen D, Agrebi R, Collet JF.

Mol Cell. 2018 May 17;70(4):614-627.e7. doi: 10.1016/j.molcel.2018.04.002. Epub 2018 May 10.

14.

Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility.

Tossounian MA, Wahni K, Van Molle I, Vertommen D, Astolfi Rosado L, Messens J.

Protein Sci. 2019 Jan;28(1):56-67. doi: 10.1002/pro.3440. Epub 2018 Jul 10.

PMID:
29732642
15.

A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.

Drappier M, Jha BK, Stone S, Elliott R, Zhang R, Vertommen D, Weiss SR, Silverman RH, Michiels T.

PLoS Pathog. 2018 Apr 13;14(4):e1006989. doi: 10.1371/journal.ppat.1006989. eCollection 2018 Apr.

16.

A Draft Map of the Human Ovarian Proteome for Tissue Engineering and Clinical Applications.

Ouni E, Vertommen D, Chiti MC, Dolmans MM, Amorim CA.

Mol Cell Proteomics. 2019 Mar 15;18(Suppl 1):S159-S173. doi: 10.1074/mcp.RA117.000469. Epub 2018 Feb 23.

17.

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation.

Bollaert E, Johanns M, Herinckx G, de Rocca Serra A, Vandewalle VA, Havelange V, Rider MH, Vertommen D, Demoulin JB.

Cell Signal. 2018 Apr;44:158-170. doi: 10.1016/j.cellsig.2018.01.014. Epub 2018 Feb 16.

PMID:
29355710
18.

Nanobodies targeting conserved epitopes on the major outer membrane protein of Campylobacter as potential tools for control of Campylobacter colonization.

Vanmarsenille C, Díaz Del Olmo I, Elseviers J, Hassanzadeh Ghassabeh G, Moonens K, Vertommen D, Martel A, Haesebrouck F, Pasmans F, Hernalsteens JP, De Greve H.

Vet Res. 2017 Dec 8;48(1):86. doi: 10.1186/s13567-017-0491-9.

19.

Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis.

Huang J, Niazi AK, Young D, Rosado LA, Vertommen D, Bodra N, Abdelgawwad MR, Vignols F, Wei B, Wahni K, Bashandy T, Bariat L, Van Breusegem F, Messens J, Reichheld JP.

J Exp Bot. 2018 Jun 19;69(14):3491-3505. doi: 10.1093/jxb/erx396.

PMID:
29194485
20.

Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.

Tossounian MA, Van Molle I, Wahni K, Jacques S, Gevaert K, Van Breusegem F, Vertommen D, Young D, Rosado LA, Messens J.

Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):775-789. doi: 10.1016/j.bbagen.2017.10.007. Epub 2017 Oct 12.

PMID:
29031766
21.

Changes in the phosphoproteome of brown adipose tissue during hibernation in the ground squirrel, Ictidomys tridecemlineatus.

Herinckx G, Hussain N, Opperdoes FR, Storey KB, Rider MH, Vertommen D.

Physiol Genomics. 2017 Sep 1;49(9):462-472. doi: 10.1152/physiolgenomics.00038.2017. Epub 2017 Jul 10.

22.

Generation of Nanobodies against SlyD and development of tools to eliminate this bacterial contaminant from recombinant proteins.

Hu Y, Romão E, Vertommen D, Vincke C, Morales-Yánez F, Gutiérrez C, Liu C, Muyldermans S.

Protein Expr Purif. 2017 Sep;137:64-76. doi: 10.1016/j.pep.2017.06.016. Epub 2017 Jun 28.

PMID:
28668496
23.

Direct and indirect activation of eukaryotic elongation factor 2 kinase by AMP-activated protein kinase.

Johanns M, Pyr Dit Ruys S, Houddane A, Vertommen D, Herinckx G, Hue L, Proud CG, Rider MH.

Cell Signal. 2017 Aug;36:212-221. doi: 10.1016/j.cellsig.2017.05.010. Epub 2017 May 11.

PMID:
28502587
24.

Effects of genetic deletion of soluble 5'-nucleotidases NT5C1A and NT5C2 on AMPK activation and nucleotide levels in contracting mouse skeletal muscles.

Kviklyte S, Vertommen D, Yerna X, Andersén H, Xu X, Gailly P, Bohlooly-Y M, Oscarsson J, Rider MH.

Am J Physiol Endocrinol Metab. 2017 Jul 1;313(1):E48-E62. doi: 10.1152/ajpendo.00304.2016. Epub 2017 Mar 21.

25.

Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes.

Houddane A, Bultot L, Novellasdemunt L, Johanns M, Gueuning MA, Vertommen D, Coulie PG, Bartrons R, Hue L, Rider MH.

Cell Signal. 2017 Jun;34:23-37. doi: 10.1016/j.cellsig.2017.02.019. Epub 2017 Feb 22.

PMID:
28235572
26.

A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast.

Collard F, Baldin F, Gerin I, Bolsée J, Noël G, Graff J, Veiga-da-Cunha M, Stroobant V, Vertommen D, Houddane A, Rider MH, Linster CL, Van Schaftingen E, Bommer GT.

Nat Chem Biol. 2016 Aug;12(8):601-7. doi: 10.1038/nchembio.2104. Epub 2016 Jun 13.

PMID:
27294321
27.

ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan.

Gerin I, Ury B, Breloy I, Bouchet-Seraphin C, Bolsée J, Halbout M, Graff J, Vertommen D, Muccioli GG, Seta N, Cuisset JM, Dabaj I, Quijano-Roy S, Grahn A, Van Schaftingen E, Bommer GT.

Nat Commun. 2016 May 19;7:11534. doi: 10.1038/ncomms11534.

28.

Comprehensively Characterizing the Thioredoxin Interactome In Vivo Highlights the Central Role Played by This Ubiquitous Oxidoreductase in Redox Control.

Arts IS, Vertommen D, Baldin F, Laloux G, Collet JF.

Mol Cell Proteomics. 2016 Jun;15(6):2125-40. doi: 10.1074/mcp.M115.056440. Epub 2016 Apr 14.

29.

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.

Johanns M, Lai YC, Hsu MF, Jacobs R, Vertommen D, Van Sande J, Dumont JE, Woods A, Carling D, Hue L, Viollet B, Foretz M, Rider MH.

Nat Commun. 2016 Mar 8;7:10856. doi: 10.1038/ncomms10856.

30.

Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons.

Gennaris A, Ezraty B, Henry C, Agrebi R, Vergnes A, Oheix E, Bos J, Leverrier P, Espinosa L, Szewczyk J, Vertommen D, Iranzo O, Collet JF, Barras F.

Nature. 2015 Dec 17;528(7582):409-412. doi: 10.1038/nature15764. Epub 2015 Dec 7.

31.

The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication.

Kreit M, Vertommen D, Gillet L, Michiels T.

PLoS One. 2015 Jul 21;10(7):e0133190. doi: 10.1371/journal.pone.0133190. eCollection 2015.

32.

The Corynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species-scavenging enzyme that shows promiscuity in thiol redox control.

Pedre B, Van Molle I, Villadangos AF, Wahni K, Vertommen D, Turell L, Erdogan H, Mateos LM, Messens J.

Mol Microbiol. 2015 Jun;96(6):1176-91. doi: 10.1111/mmi.12998. Epub 2015 Apr 11.

33.

Corynebacterium diphtheriae methionine sulfoxide reductase a exploits a unique mycothiol redox relay mechanism.

Tossounian MA, Pedre B, Wahni K, Erdogan H, Vertommen D, Van Molle I, Messens J.

J Biol Chem. 2015 May 1;290(18):11365-75. doi: 10.1074/jbc.M114.632596. Epub 2015 Mar 9.

34.

Endoplasmic reticulum Ca(2+) content decrease by PKA-dependent hyperphosphorylation of type 1 IP3 receptor contributes to prostate cancer cell resistance to androgen deprivation.

Boutin B, Tajeddine N, Monaco G, Molgo J, Vertommen D, Rider M, Parys JB, Bultynck G, Gailly P.

Cell Calcium. 2015 Apr;57(4):312-20. doi: 10.1016/j.ceca.2015.02.004. Epub 2015 Feb 18.

PMID:
25740420
35.

Detecting envelope stress by monitoring β-barrel assembly.

Cho SH, Szewczyk J, Pesavento C, Zietek M, Banzhaf M, Roszczenko P, Asmar A, Laloux G, Hov AK, Leverrier P, Van der Henst C, Vertommen D, Typas A, Collet JF.

Cell. 2014 Dec 18;159(7):1652-64. doi: 10.1016/j.cell.2014.11.045.

36.

Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle.

Plaideau C, Lai YC, Kviklyte S, Zanou N, Löfgren L, Andersén H, Vertommen D, Gailly P, Hue L, Bohlooly-Y M, Hallén S, Rider MH.

Chem Biol. 2014 Nov 20;21(11):1497-1510. doi: 10.1016/j.chembiol.2014.09.013.

37.

Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling.

Wang X, Regufe da Mota S, Liu R, Moore CE, Xie J, Lanucara F, Agarwala U, Pyr Dit Ruys S, Vertommen D, Rider MH, Eyers CE, Proud CG.

Mol Cell Biol. 2014 Nov 15;34(22):4088-103. doi: 10.1128/MCB.01035-14. Epub 2014 Sep 2.

38.

Quantification of osmotic water transport in vivo using fluorescent albumin.

Morelle J, Sow A, Vertommen D, Jamar F, Rippe B, Devuyst O.

Am J Physiol Renal Physiol. 2014 Oct 15;307(8):F981-9. doi: 10.1152/ajprenal.00098.2014. Epub 2014 Aug 6.

39.

Sulfenome mining in Arabidopsis thaliana.

Waszczak C, Akter S, Eeckhout D, Persiau G, Wahni K, Bodra N, Van Molle I, De Smet B, Vertommen D, Gevaert K, De Jaeger G, Van Montagu M, Messens J, Van Breusegem F.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11545-50. doi: 10.1073/pnas.1411607111. Epub 2014 Jul 21.

40.

Wheat germ in vitro translation to produce one of the most toxic sodium channel specific toxins.

Gad W, Ben-Abderrazek R, Wahni K, Vertommen D, Muyldermans S, Bouhaouala-Zahar B, Messens J.

Biosci Rep. 2014 Jul 29;34(4). pii: e00122. doi: 10.1042/BSR20140050.

41.

Metabolite proofreading in carnosine and homocarnosine synthesis: molecular identification of PM20D2 as β-alanyl-lysine dipeptidase.

Veiga-da-Cunha M, Chevalier N, Stroobant V, Vertommen D, Van Schaftingen E.

J Biol Chem. 2014 Jul 11;289(28):19726-36. doi: 10.1074/jbc.M114.576579. Epub 2014 Jun 2.

42.

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.

Lai YC, Kviklyte S, Vertommen D, Lantier L, Foretz M, Viollet B, Hallén S, Rider MH.

Biochem J. 2014 Jun 15;460(3):363-75. doi: 10.1042/BJ20131673.

PMID:
24665903
43.

A new role for Escherichia coli DsbC protein in protection against oxidative stress.

Denoncin K, Vertommen D, Arts IS, Goemans CV, Rahuel-Clermont S, Messens J, Collet JF.

J Biol Chem. 2014 May 2;289(18):12356-64. doi: 10.1074/jbc.M114.554055. Epub 2014 Mar 14.

44.

Mycothiol/mycoredoxin 1-dependent reduction of the peroxiredoxin AhpE from Mycobacterium tuberculosis.

Hugo M, Van Laer K, Reyes AM, Vertommen D, Messens J, Radi R, Trujillo M.

J Biol Chem. 2014 Feb 21;289(8):5228-39. doi: 10.1074/jbc.M113.510248. Epub 2013 Dec 30.

45.

Dissecting the machinery that introduces disulfide bonds in Pseudomonas aeruginosa.

Arts IS, Ball G, Leverrier P, Garvis S, Nicolaes V, Vertommen D, Ize B, Tamu Dufe V, Messens J, Voulhoux R, Collet JF.

MBio. 2013 Dec 10;4(6):e00912-13. doi: 10.1128/mBio.00912-13.

46.

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle.

Liu Y, Lai YC, Hill EV, Tyteca D, Carpentier S, Ingvaldsen A, Vertommen D, Lantier L, Foretz M, Dequiedt F, Courtoy PJ, Erneux C, Viollet B, Shepherd PR, Tavaré JM, Jensen J, Rider MH.

Biochem J. 2013 Oct 15;455(2):195-206. doi: 10.1042/BJ20130644.

PMID:
23905686
47.

Glutathione S-transferases interact with AMP-activated protein kinase: evidence for S-glutathionylation and activation in vitro.

Klaus A, Zorman S, Berthier A, Polge C, Ramirez S, Michelland S, Sève M, Vertommen D, Rider M, Lentze N, Auerbach D, Schlattner U.

PLoS One. 2013 May 31;8(5):e62497. doi: 10.1371/journal.pone.0062497. Print 2013.

48.

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle.

Liu Y, Vertommen D, Rider MH, Lai YC.

Cell Signal. 2013 Sep;25(9):1877-86. doi: 10.1016/j.cellsig.2013.05.005. Epub 2013 May 22.

PMID:
23707523
49.

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli.

Novellasdemunt L, Bultot L, Manzano A, Ventura F, Rosa JL, Vertommen D, Rider MH, Navarro-Sabate À, Bartrons R.

Biochem J. 2013 Jun 15;452(3):531-43. doi: 10.1042/BJ20121886.

PMID:
23548149
50.

Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria.

Van Laer K, Buts L, Foloppe N, Vertommen D, Van Belle K, Wahni K, Roos G, Nilsson L, Mateos LM, Rawat M, van Nuland NA, Messens J.

Mol Microbiol. 2012 Nov;86(4):787-804. doi: 10.1111/mmi.12030. Epub 2012 Sep 27.

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