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Items: 1 to 50 of 141

1.

Vdr expression in osteoclast precursors is not critical in bone homeostasis.

Verlinden L, Janssens I, Doms S, Vanhevel J, Carmeliet G, Verstuyf A.

J Steroid Biochem Mol Biol. 2019 Dec;195:105478. doi: 10.1016/j.jsbmb.2019.105478. Epub 2019 Sep 24.

PMID:
31561003
2.

Vitamin D Modulates the Response of Bronchial Epithelial Cells Exposed to Cigarette Smoke Extract.

Mathyssen C, Serré J, Sacreas A, Everaerts S, Maes K, Verleden S, Verlinden L, Verstuyf A, Pilette C, Gayan-Ramirez G, Vanaudenaerde B, Janssens W.

Nutrients. 2019 Sep 6;11(9). pii: E2138. doi: 10.3390/nu11092138.

3.

WY 1048, a 17-methyl 19-nor D-ring analog of vitamin D3, in combination with risedronate restores bone mass in a mouse model of postmenopausal osteoporosis.

Doms S, Verlinden L, Vanhevel J, Janssens I, Bouillon R, De Clercq P, Verstuyf A.

J Steroid Biochem Mol Biol. 2019 Apr;188:124-130. doi: 10.1016/j.jsbmb.2018.12.016. Epub 2019 Jan 3.

PMID:
30611910
4.

Thin bones: Vitamin D and calcium handling after bariatric surgery.

Corbeels K, Verlinden L, Lannoo M, Simoens C, Matthys C, Verstuyf A, Meulemans A, Carmeliet G, Van der Schueren B.

Bone Rep. 2018 Feb 2;8:57-63. doi: 10.1016/j.bonr.2018.02.002. eCollection 2018 Jun.

5.

Impact on Experimental Colitis of Vitamin D Receptor Deletion in Intestinal Epithelial or Myeloid Cells.

Leyssens C, Verlinden L, De Hertogh G, Kato S, Gysemans C, Mathieu C, Carmeliet G, Verstuyf A.

Endocrinology. 2017 Jul 1;158(7):2354-2366. doi: 10.1210/en.2017-00139.

PMID:
28472309
6.

1β,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum.

Pauwels S, Jans I, Billen J, Heijboer A, Verstuyf A, Carmeliet G, Mathieu C, Maestro M, Waelkens E, Evenepoel P, Bouillon R, Vanderschueren D, Vermeersch P.

J Steroid Biochem Mol Biol. 2017 Oct;173:341-348. doi: 10.1016/j.jsbmb.2017.02.004. Epub 2017 Feb 11.

PMID:
28193495
7.

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)2D3 in osteoblasts.

Ryynänen J, Kriebitzsch C, Meyer MB, Janssens I, Pike JW, Verlinden L, Verstuyf A.

J Steroid Biochem Mol Biol. 2017 Oct;173:185-193. doi: 10.1016/j.jsbmb.2017.02.005. Epub 2017 Feb 9.

PMID:
28189595
8.

Is Vitamin D2 Really Bioequivalent to Vitamin D3?

Bouillon R, Verlinden L, Verstuyf A.

Endocrinology. 2016 Sep;157(9):3384-7. doi: 10.1210/en.2016-1528. No abstract available.

PMID:
27580803
9.

Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice.

Vangoitsenhoven R, Wolden-Kirk H, Lemaire K, Verstuyf A, Verlinden L, Yamamoto Y, Kato S, Van Lommel L, Schuit F, Van der Schueren B, Mathieu C, Overbergh L.

J Steroid Biochem Mol Biol. 2016 Nov;164:309-317. doi: 10.1016/j.jsbmb.2016.02.011. Epub 2016 Feb 11.

PMID:
26877201
10.

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.

Christakos S, Dhawan P, Verstuyf A, Verlinden L, Carmeliet G.

Physiol Rev. 2016 Jan;96(1):365-408. doi: 10.1152/physrev.00014.2015. Review.

11.

Semaphorin signaling in bone.

Verlinden L, Vanderschueren D, Verstuyf A.

Mol Cell Endocrinol. 2016 Sep 5;432:66-74. doi: 10.1016/j.mce.2015.09.009. Epub 2015 Sep 11. Review.

PMID:
26365296
12.

The proapoptotic protein Bim is up regulated by 1α,25-dihydroxyvitamin D3 and its receptor agonist in endothelial cells and transformed by viral GPCR associated to Kaposi sarcoma.

Suares A, Russo de Boland A, Verstuyf A, Boland R, González-Pardo V.

Steroids. 2015 Oct;102:85-91. doi: 10.1016/j.steroids.2015.08.005. Epub 2015 Aug 6.

PMID:
26254608
13.

Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation.

Eelen G, Verlinden L, Maes C, Beullens I, Gysemans C, Paik JH, DePinho RA, Bouillon R, Carmeliet G, Verstuyf A.

J Steroid Biochem Mol Biol. 2016 Nov;164:337-343. doi: 10.1016/j.jsbmb.2015.07.015. Epub 2015 Jul 29.

PMID:
26232637
14.

Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways.

Ferreira GB, Vanherwegen AS, Eelen G, Gutiérrez ACF, Van Lommel L, Marchal K, Verlinden L, Verstuyf A, Nogueira T, Georgiadou M, Schuit F, Eizirik DL, Gysemans C, Carmeliet P, Overbergh L, Mathieu C.

Cell Rep. 2015 Feb 10;10(5):711-725. doi: 10.1016/j.celrep.2015.01.013. Epub 2015 Feb 7.

15.

Remodeling of phospholipid composition in colon cancer cells by 1α,25(OH)2D3 and its analogs.

Leyssens C, Marien E, Verlinden L, Derua R, Waelkens E, Swinnen JV, Verstuyf A.

J Steroid Biochem Mol Biol. 2015 Apr;148:172-8. doi: 10.1016/j.jsbmb.2015.01.018. Epub 2015 Jan 24. Review.

PMID:
25625664
16.

1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.

Van Belle TL, Vanherwegen AS, Feyaerts D, De Clercq P, Verstuyf A, Korf H, Gysemans C, Mathieu C.

PLoS One. 2014 Oct 3;9(10):e109194. doi: 10.1371/journal.pone.0109194. eCollection 2014.

17.

The future of vitamin D analogs.

Leyssens C, Verlinden L, Verstuyf A.

Front Physiol. 2014 Apr 3;5:122. doi: 10.3389/fphys.2014.00122. eCollection 2014. Review.

18.

1,25-Dihydroxyvitamin D3 promotes tolerogenic dendritic cells with functional migratory properties in NOD mice.

Ferreira GB, Gysemans CA, Demengeot J, da Cunha JP, Vanherwegen AS, Overbergh L, Van Belle TL, Pauwels F, Verstuyf A, Korf H, Mathieu C.

J Immunol. 2014 May 1;192(9):4210-20. doi: 10.4049/jimmunol.1302350. Epub 2014 Mar 24.

19.

Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in NOD mice when given early and long term.

Takiishi T, Ding L, Baeke F, Spagnuolo I, Sebastiani G, Laureys J, Verstuyf A, Carmeliet G, Dotta F, Van Belle TL, Gysemans CA, Mathieu C.

Diabetes. 2014 Jun;63(6):2026-36. doi: 10.2337/db13-1559. Epub 2014 Feb 18.

20.

Cell cycle arrest and apoptosis induced by 1α,25(OH)2D3 and TX 527 in Kaposi sarcoma is VDR dependent.

González-Pardo V, Suares A, Verstuyf A, De Clercq P, Boland R, de Boland AR.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:197-200. doi: 10.1016/j.jsbmb.2013.11.014. Epub 2013 Dec 5. Review.

PMID:
24316429
21.

Vitamin D and energy homeostasis: of mice and men.

Bouillon R, Carmeliet G, Lieben L, Watanabe M, Perino A, Auwerx J, Schoonjans K, Verstuyf A.

Nat Rev Endocrinol. 2014 Feb;10(2):79-87. doi: 10.1038/nrendo.2013.226. Epub 2013 Nov 19. Review.

PMID:
24247221
22.

A proteomic approach on the effects of TX527, a 1α,25-dihydroxyvitamin D3 analog, in human T lymphocytes.

Ferreira GB, Baeke F, Verstuyf A, De Clercq P, Waelkens E, Mathieu C, Overbergh L.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:96-101. doi: 10.1016/j.jsbmb.2013.10.013. Epub 2013 Oct 28.

PMID:
24176759
23.

Vitamin D in thyroid tumorigenesis and development.

Clinckspoor I, Verlinden L, Mathieu C, Bouillon R, Verstuyf A, Decallonne B.

Prog Histochem Cytochem. 2013 Aug;48(2):65-98. doi: 10.1016/j.proghi.2013.07.001. Epub 2013 Jul 26. Review.

PMID:
23890557
24.

Vitamin D action: lessons from VDR and Cyp27b1 null mice.

Bouillon R, Lieben L, Mathieu C, Verstuyf A, Carmeliet G.

Pediatr Endocrinol Rev. 2013 Jun;10 Suppl 2:354-66. Review.

PMID:
23858619
25.

Vitamin D analogue TX 527 down-regulates the NF-κB pathway and controls the proliferation of endothelial cells transformed by Kaposi sarcoma herpesvirus.

González-Pardo V, Verstuyf A, Boland R, Russo de Boland A.

Br J Pharmacol. 2013 Aug;169(7):1635-45. doi: 10.1111/bph.12219.

26.

Nrp2 deficiency leads to trabecular bone loss and is accompanied by enhanced osteoclast and reduced osteoblast numbers.

Verlinden L, Kriebitzsch C, Beullens I, Tan BK, Carmeliet G, Verstuyf A.

Bone. 2013 Aug;55(2):465-75. doi: 10.1016/j.bone.2013.03.023. Epub 2013 Apr 15.

PMID:
23598046
27.

PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D.

Vanoirbeek E, Eelen G, Verlinden L, Carmeliet G, Mathieu C, Bouillon R, O'Connor R, Xiao G, Verstuyf A.

Oncogene. 2014 Apr 10;33(15):1904-11. doi: 10.1038/onc.2013.123. Epub 2013 Apr 15.

PMID:
23584482
28.

Vitamin D and cancer.

Verstuyf A, Bouillon R.

Cell Cycle. 2013 Apr 1;12(7):1018. doi: 10.4161/cc.24306. Epub 2013 Mar 19. No abstract available.

29.

Vitamin D, mitochondria, and muscle.

Bouillon R, Verstuyf A.

J Clin Endocrinol Metab. 2013 Mar;98(3):961-3. doi: 10.1210/jc.2013-1352. No abstract available.

PMID:
23472232
30.

Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer.

Leyssens C, Verlinden L, Verstuyf A.

Endocr Relat Cancer. 2013 Mar 22;20(2):R31-47. doi: 10.1530/ERC-12-0381. Print 2013 Apr. Review.

PMID:
23319494
31.

The odd-skipped related genes Osr1 and Osr2 are induced by 1,25-dihydroxyvitamin D3.

Verlinden L, Kriebitzsch C, Eelen G, Van Camp M, Leyssens C, Tan BK, Beullens I, Verstuyf A.

J Steroid Biochem Mol Biol. 2013 Jul;136:94-7. doi: 10.1016/j.jsbmb.2012.12.001. Epub 2012 Dec 10. Review.

PMID:
23238298
32.

1α,25-Dihydroxyvitamin D3 and its analogs as modulators of human dendritic cells: a comparison dose-titration study.

Ferreira GB, Overbergh L, Verstuyf A, Mathieu C.

J Steroid Biochem Mol Biol. 2013 Jul;136:160-5. doi: 10.1016/j.jsbmb.2012.10.009. Epub 2012 Oct 23. Review.

PMID:
23098690
33.

The vitamin d receptor in thyroid development and function.

Clinckspoor I, Gérard AC, Van Sande J, Many MC, Verlinden L, Bouillon R, Carmeliet G, Mathieu C, Verstuyf A, Decallonne B.

Eur Thyroid J. 2012 Oct;1(3):168-75. doi: 10.1159/000342363. Epub 2012 Sep 22.

34.

The vitamin D analog TX527 ameliorates disease symptoms in a chemically induced model of inflammatory bowel disease.

Verlinden L, Leyssens C, Beullens I, Marcelis S, Mathieu C, De Clercq P, Verstuyf A.

J Steroid Biochem Mol Biol. 2013 Jul;136:107-11. doi: 10.1016/j.jsbmb.2012.09.017. Epub 2012 Sep 20.

PMID:
23000190
35.

1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts.

Eelen G, Verlinden L, Meyer MB, Gijsbers R, Pike JW, Bouillon R, Verstuyf A.

J Steroid Biochem Mol Biol. 2013 Jul;136:112-9. doi: 10.1016/j.jsbmb.2012.09.011. Epub 2012 Sep 16.

PMID:
22989484
36.

Extraskeletal effects of vitamin D.

Wolden-Kirk H, Gysemans C, Verstuyf A, Mathieu C.

Endocrinol Metab Clin North Am. 2012 Sep;41(3):571-94. doi: 10.1016/j.ecl.2012.05.004. Epub 2012 Jun 29. Review.

PMID:
22877430
37.

NFκB pathway is down-regulated by 1α,25(OH)(2)-vitamin D(3) in endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein coupled receptor.

Gonzalez-Pardo V, D'Elia N, Verstuyf A, Boland R, Russo de Boland A.

Steroids. 2012 Sep;77(11):1025-32. doi: 10.1016/j.steroids.2012.05.006. Epub 2012 Jun 7.

PMID:
22683670
38.

Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency.

Hatse S, Lambrechts D, Verstuyf A, Smeets A, Brouwers B, Vandorpe T, Brouckaert O, Peuteman G, Laenen A, Verlinden L, Kriebitzsch C, Dieudonné AS, Paridaens R, Neven P, Christiaens MR, Bouillon R, Wildiers H.

Carcinogenesis. 2012 Jul;33(7):1319-26. doi: 10.1093/carcin/bgs187. Epub 2012 May 23.

PMID:
22623648
39.

Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.

Clinckspoor I, Hauben E, Verlinden L, Van den Bruel A, Vanwalleghem L, Vander Poorten V, Delaere P, Mathieu C, Verstuyf A, Decallonne B.

J Histochem Cytochem. 2012 Jul;60(7):502-11. doi: 10.1369/0022155412447296. Epub 2012 Apr 17.

40.

Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth.

Helsen C, Marchand A, Chaltin P, Munck S, Voet A, Verstuyf A, Claessens F.

Mol Cancer Ther. 2012 Jun;11(6):1257-68. doi: 10.1158/1535-7163.MCT-11-0763. Epub 2012 Apr 10.

41.

Straight from D-Heart: vitamin D status and cardiovascular disease.

Van der Schueren BJ, Verstuyf A, Mathieu C.

Curr Opin Lipidol. 2012 Feb;23(1):17-23. doi: 10.1097/MOL.0b013e32834d7357. Review.

PMID:
22123672
42.

1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo.

Ferreira GB, van Etten E, Verstuyf A, Waer M, Overbergh L, Gysemans C, Mathieu C.

Diabetes Metab Res Rev. 2011 Nov;27(8):933-41. doi: 10.1002/dmrr.1275.

PMID:
22069288
43.

1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.

Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A.

J Bone Miner Res. 2011 Dec;26(12):2991-3000. doi: 10.1002/jbmr.493.

44.

Calcium and vitamin d supplementation in men.

Gielen E, Boonen S, Vanderschueren D, Sinnesael M, Verstuyf A, Claessens F, Milisen K, Verschueren S.

J Osteoporos. 2011;2011:875249. doi: 10.4061/2011/875249. Epub 2011 Aug 25.

45.

The anti-cancer and anti-inflammatory actions of 1,25(OH)₂D₃.

Vanoirbeek E, Krishnan A, Eelen G, Verlinden L, Bouillon R, Feldman D, Verstuyf A.

Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):593-604. doi: 10.1016/j.beem.2011.05.001. Review.

46.

Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18.

Verlinden L, Verstuyf A, Eelen G, Bouillon R, Ordóñez-Morán P, Larriba MJ, Muñoz A, Rochel N, Sato Y, Moras D, Maestro M, Seoane S, Dominguez F, Eduardo-Canosa S, Nicoletti D, Moman E, Mouriño A.

ChemMedChem. 2011 May 2;6(5):788-93. doi: 10.1002/cmdc.201100021. Epub 2011 Mar 29.

47.

1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer.

Clinckspoor I, Verlinden L, Overbergh L, Korch C, Bouillon R, Mathieu C, Verstuyf A, Decallonne B.

J Steroid Biochem Mol Biol. 2011 Mar;124(1-2):1-9. doi: 10.1016/j.jsbmb.2010.12.008. Epub 2010 Dec 21.

PMID:
21182945
48.

The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.

Baeke F, Korf H, Overbergh L, Verstuyf A, Thorrez L, Van Lommel L, Waer M, Schuit F, Gysemans C, Mathieu C.

J Immunol. 2011 Jan 1;186(1):132-42. doi: 10.4049/jimmunol.1000695. Epub 2010 Dec 3.

49.

Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation.

Baker CM, Verstuyf A, Jensen KB, Watt FM.

Dev Biol. 2010 Jul 1;343(1-2):40-50. doi: 10.1016/j.ydbio.2010.04.005. Epub 2010 Apr 14.

50.

Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system.

Baeke F, Korf H, Overbergh L, van Etten E, Verstuyf A, Gysemans C, Mathieu C.

J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):221-7. doi: 10.1016/j.jsbmb.2010.03.037. Epub 2010 Mar 17.

PMID:
20302932

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