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Patients with rheumatoid arthritis facing sick leave or work disability meet varying regulations: a study among rheumatologists and patients from 44 European countries.

Putrik P, Ramiro S, Guillemin F, Péntek M, Sivera F, Sokka T, de Wit M, Woolf AD, Zink A, Andersone D, Berghea F, Butrimiene I, Brouwer S, Cassar K, Charalambous P, Caporali R, Deseatnicova E, Damjanov NS, Finckh A, FitzGerald O, Gröndal G, Gobejishjvili N, Gluszko P, Hirsch M, Jovanovic I, Vencovský J, Janssens X, Keszei AP, Kovarova M, Kull M, Cunha Miranda L, Mayer M, Misevska-Percinkova S, Inanc N, Nadashkevich O, Petersson IF, Puolakka K, Rojkovich B, Radner H, Szabados F, Slobodin G, Shirinsky I, Soroka N, Sidiropoulos P, Shumnalieva R, Sokolovic S, Shukurova S, Tafaj A, Tomšič M, Uhlig T, Verstappen SMM, Boonen A.

Ann Rheum Dis. 2019 Aug 19. pii: annrheumdis-2019-215294. doi: 10.1136/annrheumdis-2019-215294. [Epub ahead of print]


A UK study: vocational experiences of young adults with juvenile idiopathic arthritis.

Lunt LE, Bosworth A, Bezzant M, Walker-Bone K, Hyrich KL, Thomson W, McDonagh JE, Verstappen SMM.

Pediatr Rheumatol Online J. 2019 Aug 6;17(1):54. doi: 10.1186/s12969-019-0357-y. No abstract available.


The predictors of and reasons for non-adherence in an observational cohort of patients with rheumatoid arthritis commencing methotrexate.

Hope HF, Hyrich KL, Anderson J, Bluett J, Sergeant JC, Barton A, Cordingley L, Verstappen SMM; RAMS co-investigators .

Rheumatology (Oxford). 2019 Jul 13. pii: kez274. doi: 10.1093/rheumatology/kez274. [Epub ahead of print]


Corrigendum to "Overview of changes in RMD epidemiology and outcome development in the last 10 years" [Best Pract Res Clin Rheumatol 32 (2018) 169-173].

Verstappen SMM, Carmona L.

Best Pract Res Clin Rheumatol. 2018 Aug;32(4):618. doi: 10.1016/j.berh.2019.01.001. Epub 2019 Feb 7. No abstract available.


Development and validation of a methotrexate adherence assay.

Bluett J, Riba-Garcia I, Verstappen SMM, Wendling T, Ogungbenro K, Unwin RD, Barton A.

Ann Rheum Dis. 2019 Sep;78(9):1192-1197. doi: 10.1136/annrheumdis-2019-215446. Epub 2019 Jun 5.


Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity.

Pan Y, Norton S, Gwinnutt JM, Kearsley-Fleet L, Symmons DPM, Lunt M, Young A; BSRBR-RA Control Centre Consortium, Hyrich KL, Verstappen SMM.

PLoS One. 2019 May 20;14(5):e0215999. doi: 10.1371/journal.pone.0215999. eCollection 2019.


A Systematic Review of Productivity in Economic Evaluations of Workplace Interventions: A Need for Reporting Criteria?

Jones C, Verstappen SMM, Payne K.

Appl Health Econ Health Policy. 2019 Apr 1. doi: 10.1007/s40258-019-00473-8. [Epub ahead of print] Review.


Considerations for Evaluating and Recommending Worker Productivity Outcome Measures: An Update from the OMERACT Worker Productivity Group.

Verstappen SMM, Lacaille D, Boonen A, Escorpizo R, Hofstetter C, Bosworth A, Leong A, Leggett S, Gignac MAM, Wallman JK, Terwee MM, Berghea F, Agaliotis M, Tugwell P, Beaton D.

J Rheumatol. 2019 Apr 1. pii: jrheum.181201. doi: 10.3899/jrheum.181201. [Epub ahead of print]


Comparing Proxy, Adolescent and Adult Assessments of Functional Ability in Adolescents with Juvenile Idiopathic Arthritis.

Shoop-Worrall SJW, Hyrich KL, Verstappen SM, Sergeant JC, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, McDonagh JE.

Arthritis Care Res (Hoboken). 2019 Mar 15. doi: 10.1002/acr.23877. [Epub ahead of print]


Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis.

Hensor EMA, McKeigue P, Ling SF, Colombo M, Barrett JH, Nam JL, Freeston J, Buch MH, Spiliopoulou A, Agakov F, Kelly S, Lewis MJ, Verstappen SMM, MacGregor AJ, Viatte S, Barton A, Pitzalis C, Emery P, Conaghan PG, Morgan AW.

Rheumatology (Oxford). 2019 Mar 1. pii: kez049. doi: 10.1093/rheumatology/kez049. [Epub ahead of print]


Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease.

Hope HF, Binkley GM, Fenton S, Kitas GD, Verstappen SMM, Symmons DPM.

PLoS One. 2019 Jan 17;14(1):e0201196. doi: 10.1371/journal.pone.0201196. eCollection 2019.


Profiling of Gene Expression Biomarkers as a Classifier of Methotrexate Nonresponse in Patients With Rheumatoid Arthritis.

Plant D, Maciejewski M, Smith S, Nair N; Maximising Therapeutic Utility in Rheumatoid Arthritis Consortium, the RAMS Study Group, Hyrich K, Ziemek D, Barton A, Verstappen S.

Arthritis Rheumatol. 2019 May;71(5):678-684. doi: 10.1002/art.40810. Epub 2019 Mar 19.


Overview of changes in RMD epidemiology and outcome development in the last 10 years.

Verstappen SMM, Carmona L.

Best Pract Res Clin Rheumatol. 2018 Apr;32(2):169-173. doi: 10.1016/j.berh.2018.10.008. Epub 2018 Nov 17. Erratum in: Best Pract Res Clin Rheumatol. 2018 Aug;32(4):618.


Epidemiology of rheumatic and musculoskeletal diseases.

Verstappen SMM, Carmona L.

Best Pract Res Clin Rheumatol. 2018 Apr;32(2):167-168. doi: 10.1016/j.berh.2018.11.002. No abstract available.


Conceptual model for the health technology assessment of current and novel interventions in rheumatoid arthritis.

Alemao E, Al MJ, Boonen AA, Stevenson MD, Verstappen SMM, Michaud K, Weinblatt ME, Rutten-van Mölken MPMH.

PLoS One. 2018 Oct 5;13(10):e0205013. doi: 10.1371/journal.pone.0205013. eCollection 2018.


The prevalence of co-morbidities and their impact on physical activity in people with inflammatory rheumatic diseases compared with the general population: results from the UK Biobank.

Cook MJ, Bellou E, Bowes J, Sergeant JC, O'Neill TW, Barton A, Verstappen SMM.

Rheumatology (Oxford). 2018 Dec 1;57(12):2172-2182. doi: 10.1093/rheumatology/key224.


Communal living: Religion, class, and the politics of dwelling in small-town Gujarat.

Verstappen S.

Contrib Indian Sociol. 2018 Feb;52(1):53-78. doi: 10.1177/0069966717743383. Epub 2017 Dec 26. No abstract available.


Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS).

Sergeant JC, Hyrich KL, Anderson J, Kopec-Harding K, Hope HF, Symmons DPM; RAMS Co-Investigators, Barton A, Verstappen SMM.

Arthritis Res Ther. 2018 Jul 13;20(1):147. doi: 10.1186/s13075-018-1645-5.


Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.

Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M, Plant D, Colombo M, Orchard P, Twigg S, McInnes IB, Porter D, Freeston JE, Nam JL, Cordell HJ, Isaacs JD, Strathdee JL, Arnett D, de Hair MJH, Tak PP, Aslibekyan S, van Vollenhoven RF, Padyukov L, Bridges SL, Pitzalis C, Cope AP, Verstappen SMM, Emery P, Barnes MR, Agakov F, McKeigue P, Mushiroda T, Kubo M, Weinshilboum R, Barton A, Morgan AW, Barrett JH; MATURA; and PAMERA; Consortia.

Pharmacogenomics J. 2018 Jul;18(4):528-538. doi: 10.1038/s41397-018-0025-5. Epub 2018 May 25. Review.


Baseline patient reported outcomes are more consistent predictors of long-term functional disability than laboratory, imaging or joint count data in patients with early inflammatory arthritis: A systematic review.

Gwinnutt JM, Sharp CA, Symmons DPM, Lunt M, Verstappen SMM.

Semin Arthritis Rheum. 2018 Dec;48(3):384-398. doi: 10.1016/j.semarthrit.2018.03.004. Epub 2018 Mar 15.


Long-Term Outcomes Following Achievement of Clinically Inactive Disease in Juvenile Idiopathic Arthritis: The Importance of Definition.

Shoop-Worrall SJW, Verstappen SMM, McDonagh JE, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, Hyrich KL.

Arthritis Rheumatol. 2018 Sep;70(9):1519-1529. doi: 10.1002/art.40519. Epub 2018 Jul 22.


Risk factors for oral methotrexate failure in patients with inflammatory polyarthritis: results from a UK prospective cohort study.

Bluett J, Sergeant JC, MacGregor AJ, Chipping JR, Marshall T, Symmons DPM, Verstappen SMM.

Arthritis Res Ther. 2018 Mar 20;20(1):50. doi: 10.1186/s13075-018-1544-9.


Have the 10-year outcomes of patients with early inflammatory arthritis improved in the new millennium compared with the decade before? Results from the Norfolk Arthritis Register.

Gwinnutt JM, Symmons DPM, MacGregor AJ, Chipping JR, Marshall T, Lunt M, Verstappen SMM.

Ann Rheum Dis. 2018 Jun;77(6):848-854. doi: 10.1136/annrheumdis-2017-212426. Epub 2018 Feb 23.


Comparison of the risks of hospitalisation for cardiovascular events in patients with rheumatoid arthritis treated with tocilizumab and etanercept.

Generali E, Carrara G, Selmi C, Verstappen SMM, Zambon A, Bortoluzzi A, Silvagni E, Scirè CA.

Clin Exp Rheumatol. 2018 Mar-Apr;36(2):310-313. Epub 2017 Dec 28.


Patterns of pain over time among children with juvenile idiopathic arthritis.

Rashid A, Cordingley L, Carrasco R, Foster HE, Baildam EM, Chieng A, Davidson JE, Wedderburn LR, Ioannou Y, McErlane F, Verstappen SMM, Hyrich KL, Thomson W.

Arch Dis Child. 2018 May;103(5):437-443. doi: 10.1136/archdischild-2017-313337. Epub 2017 Nov 25.


Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme.

Yamanaka H, Askling J, Berglind N, Franzen S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Novelli Horne L, Inoue E, Michaud K, Pappas DA, Reed G, Symmons D, Tanaka E, Tran TN, Verstappen SMM, Wesby-van Swaay E, Nyberg F.

RMD Open. 2017 Oct 10;3(2):e000498. doi: 10.1136/rmdopen-2017-000498. eCollection 2017.


Do we need bone mineral density to estimate osteoporotic fracture risk? A 10-year prospective multicentre validation study.

Marques A, Lucas R, Simões E, Verstappen SMM, Jacobs JWG, da Silva JAP.

RMD Open. 2017 Sep 26;3(2):e000509. doi: 10.1136/rmdopen-2017-000509. eCollection 2017.



Gwinnutt JM, Symmons DPM, Lunt M, Verstappen SMM.

Arthritis Rheumatol. 2017 Dec;69(12):2402-2403. doi: 10.1002/art.40311. Epub 2017 Nov 2. No abstract available.


How common is remission in juvenile idiopathic arthritis: A systematic review.

Shoop-Worrall SJW, Kearsley-Fleet L, Thomson W, Verstappen SMM, Hyrich KL.

Semin Arthritis Rheum. 2017 Dec;47(3):331-337. doi: 10.1016/j.semarthrit.2017.05.007. Epub 2017 May 20. Review.


Response to: Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis by Kremer and Weinblatt.

Humphreys JH, Costello R, Verstappen SM, Dixon WG.

Ann Rheum Dis. 2018 Jan;77(1):e5. doi: 10.1136/annrheumdis-2017-211670. Epub 2017 Jun 8. No abstract available.


Predictors of and outcomes following orthopaedic joint surgery in patients with early rheumatoid arthritis followed for 20 years.

Gwinnutt JM, Symmons DPM, MacGregor AJ, Chipping JR, Lapraik C, Marshall T, Lunt M, Verstappen SMM.

Rheumatology (Oxford). 2017 Sep 1;56(9):1510-1517. doi: 10.1093/rheumatology/kex172.


HLA-A 31:01 is not associated with the development of methotrexate pneumonitis in the UK population: results from a genome-wide association study.

Bluett J, Owen SA, Massey J, Alfirevic A, Pirmohamed M, Plant D, Verstappen SMM, Barton A; Pneumonitis Study Consortium.

Ann Rheum Dis. 2017 Dec;76(12):e51. doi: 10.1136/annrheumdis-2017-211512. Epub 2017 May 12. No abstract available.


An OMERACT Initiative Toward Consensus to Identify and Characterize Candidate Contextual Factors: Report from the Contextual Factors Working Group.

Finger ME, Boonen A, Woodworth TG, Escorpizo R, Christensen R, Nielsen SM, Leong AL, Scholte Voshaar M, Flurey CA, Milman N, Verstappen SM, Alten R, Guillemin F, Kloppenburg M, Beaton DE, Tugwell PS, March LM, Furst DE, Pohl C.

J Rheumatol. 2017 Nov;44(11):1734-1739. doi: 10.3899/jrheum.161200. Epub 2017 May 1.


Twenty-Year Outcome and Association Between Early Treatment and Mortality and Disability in an Inception Cohort of Patients With Rheumatoid Arthritis: Results From the Norfolk Arthritis Register.

Gwinnutt JM, Symmons DPM, MacGregor AJ, Chipping JR, Marshall T, Lunt M, Verstappen SMM.

Arthritis Rheumatol. 2017 Aug;69(8):1566-1575. doi: 10.1002/art.40090. Epub 2017 Jul 10.


How common is clinically inactive disease in a prospective cohort of patients with juvenile idiopathic arthritis? The importance of definition.

Shoop-Worrall SJW, Verstappen SMM, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, Hyrich KL.

Ann Rheum Dis. 2017 Aug;76(8):1381-1388. doi: 10.1136/annrheumdis-2016-210511. Epub 2017 Apr 7. Erratum in: Ann Rheum Dis. 2017 Oct;76(10):1783-1784.


Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate.

Humphreys JH, Warner A, Costello R, Lunt M, Verstappen SMM, Dixon WG.

Ann Rheum Dis. 2017 Sep;76(9):1509-1514. doi: 10.1136/annrheumdis-2016-210629. Epub 2017 Mar 23.


The impact of socio-economic status in rheumatoid arthritis.

Verstappen SMM.

Rheumatology (Oxford). 2017 Jul 1;56(7):1051-1052. doi: 10.1093/rheumatology/kew428. No abstract available.


Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

van Wesemael TJ, Ajeganova S, Humphreys J, Terao C, Muhammad A, Symmons DP, MacGregor AJ, Hafström I, Trouw LA, van der Helm-van Mil AH, Huizinga TW, Mimori T, Toes RE, Matsuda F, Svensson B, Verstappen SM, van der Woude D.

Arthritis Res Ther. 2016 Dec 1;18(1):285.


Consensus Decision Models for Biologics in Rheumatoid and Psoriatic Arthritis: Recommendations of a Multidisciplinary Working Party.

Madan J, Ades T, Barton P, Bojke L, Choy E, Helliwell P, Jobanputra P, Stein K, Stevens A, Tosh J, Verstappen S, Wailoo A.

Rheumatol Ther. 2015 Dec;2(2):113-125. Epub 2015 Nov 25.


Economic Theory and Self-Reported Measures of Presenteeism in Musculoskeletal Disease.

Jones C, Payne K, Gannon B, Verstappen S.

Curr Rheumatol Rep. 2016 Aug;18(8):53. doi: 10.1007/s11926-016-0600-1. Review.


Predictors and outcomes of sustained, intermittent or never achieving remission in patients with recent onset inflammatory polyarthritis: results from the Norfolk Arthritis Register.

Cook MJ, Diffin J, Scirè CA, Lunt M, MacGregor AJ, Symmons DP, Verstappen SM.

Rheumatology (Oxford). 2016 Sep;55(9):1601-9. doi: 10.1093/rheumatology/kew210. Epub 2016 May 24.


Response to: 'Evaluation of the association between anticarbamylated protein antibodies and longitudinal course of functional ability in rheumatoid arthritis' by Ajeganova et al.

Humphreys JH, Symmons DP, Verstappen SM.

Ann Rheum Dis. 2016 Apr;75(4):e15. doi: 10.1136/annrheumdis-2015-208957. Epub 2016 Feb 18. No abstract available.


Can rheumatoid arthritis (RA) registries provide contextual safety data for modern RA clinical trials? The case for mortality and cardiovascular disease.

Michaud K, Berglind N, Franzén S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Horne L, Inoue E, Nyberg F, Pappas DA, Reed G, Symmons D, Tanaka E, Tran TN, Verstappen SM, Wesby-van Swaay E, Yamanaka H, Askling J.

Ann Rheum Dis. 2016 Oct;75(10):1797-805. doi: 10.1136/annrheumdis-2015-208698. Epub 2016 Feb 8.


Psychological factors predict adherence to methotrexate in rheumatoid arthritis; findings from a systematic review of rates, predictors and associations with patient-reported and clinical outcomes.

Hope HF, Bluett J, Barton A, Hyrich KL, Cordingley L, Verstappen SM.

RMD Open. 2016 Jan 20;2(1):e000171. doi: 10.1136/rmdopen-2015-000171. eCollection 2016. Review.


Content validity of global measures for at-work productivity in patients with rheumatic diseases: an international qualitative study.

Leggett S, van der Zee-Neuen A, Boonen A, Beaton D, Bojinca M, Bosworth A, Dadoun S, Fautrel B, Hagel S, Hofstetter C, Lacaille D, Linton D, Mihai C, Petersson IF, Rogers P, Sciré C, Verstappen SM; at-work productivity global measure working group.

Rheumatology (Oxford). 2016 Aug;55(8):1364-73. doi: 10.1093/rheumatology/kev435. Epub 2016 Jan 21.


Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.

Ajeganova S, Humphreys JH, Verheul MK, van Steenbergen HW, van Nies JA, Hafström I, Svensson B, Huizinga TW, Trouw LA, Verstappen SM, van der Helm-van Mil AH.

Ann Rheum Dis. 2016 Nov;75(11):1924-1932. doi: 10.1136/annrheumdis-2015-208579. Epub 2016 Jan 12.


Test-retest Reliability and Correlations of 5 Global Measures Addressing At-work Productivity Loss in Patients with Rheumatic Diseases.

Leggett S, van der Zee-Neuen A, Boonen A, Beaton DE, Bojinca M, Bosworth A, Dadoun S, Fautrel B, Hagel S, Hofstetter C, Lacaille D, Linton D, Mihai C, Petersson IF, Rogers P, Sergeant JC, Sciré C, Verstappen SM; At-work Productivity Global Measure Working Group.

J Rheumatol. 2016 Feb;43(2):433-9. doi: 10.3899/jrheum.141605. Epub 2015 Dec 1.


How comparable are rates of malignancies in patients with rheumatoid arthritis across the world? A comparison of cancer rates, and means to optimise their comparability, in five RA registries.

Askling J, Berglind N, Franzen S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Horne L, Inoue E, Michaud K, Nyberg F, Pappas DA, Reed G, Tanaka E, Tran TN, Verstappen SM, Yamanaka H, Wesby-van Swaay E, Symmons D.

Ann Rheum Dis. 2016 Oct;75(10):1789-96. doi: 10.1136/annrheumdis-2015-208105. Epub 2015 Nov 30.


Rheumatoid arthritis and work: The impact of rheumatoid arthritis on absenteeism and presenteeism.

Verstappen SM.

Best Pract Res Clin Rheumatol. 2015 Jun;29(3):495-511. doi: 10.1016/j.berh.2015.06.001. Epub 2015 Jul 14. Review.


The Longitudinal Course of Fatigue in Rheumatoid Arthritis: Results from the Norfolk Arthritis Register.

Druce KL, Jones GT, Macfarlane GJ, Verstappen SM, Basu N.

J Rheumatol. 2015 Nov;42(11):2059-65. doi: 10.3899/jrheum.141498. Epub 2015 Oct 15.


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