Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 87

1.

Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome.

Storm T, Zeitz C, Cases O, Amsellem S, Verroust PJ, Madsen M, Benoist JF, Passemard S, Lebon S, Jønsson IM, Emma F, Koldsø H, Hertz JM, Nielsen R, Christensen EI, Kozyraki R.

BMC Med Genet. 2013 Oct 24;14:111. doi: 10.1186/1471-2350-14-111.

2.

Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration.

Storm T, Tranebjærg L, Frykholm C, Birn H, Verroust PJ, Nevéus T, Sundelin B, Hertz JM, Holmström G, Ericson K, Christensen EI, Nielsen R.

Nephrol Dial Transplant. 2013 Mar;28(3):585-91. doi: 10.1093/ndt/gfs462. Epub 2012 Oct 9.

PMID:
23048173
3.

Cubilin is expressed in rat and human glomerular podocytes.

Prabakaran T, Christensen EI, Nielsen R, Verroust PJ.

Nephrol Dial Transplant. 2012 Aug;27(8):3156-9. doi: 10.1093/ndt/gfr794. Epub 2012 Feb 15.

PMID:
22337902
4.

Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease.

Prabakaran T, Nielsen R, Larsen JV, Sørensen SS, Feldt-Rasmussen U, Saleem MA, Petersen CM, Verroust PJ, Christensen EI.

PLoS One. 2011;6(9):e25065. doi: 10.1371/journal.pone.0025065. Epub 2011 Sep 19.

5.

Mouse model of proximal tubule endocytic dysfunction.

Weyer K, Storm T, Shan J, Vainio S, Kozyraki R, Verroust PJ, Christensen EI, Nielsen R.

Nephrol Dial Transplant. 2011 Nov;26(11):3446-51. doi: 10.1093/ndt/gfr525. Epub 2011 Sep 16.

PMID:
21926402
6.

A patient with cubilin deficiency.

Storm T, Emma F, Verroust PJ, Hertz JM, Nielsen R, Christensen EI.

N Engl J Med. 2011 Jan 6;364(1):89-91. doi: 10.1056/NEJMc1009804. No abstract available.

PMID:
21208123
7.

Cubilin is essential for albumin reabsorption in the renal proximal tubule.

Amsellem S, Gburek J, Hamard G, Nielsen R, Willnow TE, Devuyst O, Nexo E, Verroust PJ, Christensen EI, Kozyraki R.

J Am Soc Nephrol. 2010 Nov;21(11):1859-67. doi: 10.1681/ASN.2010050492. Epub 2010 Aug 26.

8.

Renal proximal tubular dysfunction is a major determinant of urinary connective tissue growth factor excretion.

Gerritsen KG, Peters HP, Nguyen TQ, Koeners MP, Wetzels JF, Joles JA, Christensen EI, Verroust PJ, Li D, Oliver N, Xu L, Kok RJ, Goldschmeding R.

Am J Physiol Renal Physiol. 2010 Jun;298(6):F1457-64. doi: 10.1152/ajprenal.00694.2009. Epub 2010 Mar 17.

9.

Receptor-mediated endocytosis in renal proximal tubule.

Christensen EI, Verroust PJ, Nielsen R.

Pflugers Arch. 2009 Oct;458(6):1039-48. doi: 10.1007/s00424-009-0685-8. Epub 2009 Jun 5. Review.

PMID:
19499243
10.

Interstitial fibrosis: tubular hypothesis versus glomerular hypothesis.

Christensen EI, Verroust PJ.

Kidney Int. 2008 Nov;74(10):1233-6. doi: 10.1038/ki.2008.421. Review.

11.

Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney.

Christensen EI, Raciti D, Reggiani L, Verroust PJ, Brändli AW.

Pflugers Arch. 2008 Sep;456(6):1163-76. doi: 10.1007/s00424-008-0488-3. Epub 2008 Jun 13.

PMID:
18551302
12.

Megalin-dependent internalization of cadmium-metallothionein and cytotoxicity in cultured renal proximal tubule cells.

Wolff NA, Abouhamed M, Verroust PJ, Thévenod F.

J Pharmacol Exp Ther. 2006 Aug;318(2):782-91. Epub 2006 May 11.

PMID:
16690719
13.

Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex.

Coudroy G, Gburek J, Kozyraki R, Madsen M, Trugnan G, Moestrup SK, Verroust PJ, Maurice M.

J Am Soc Nephrol. 2005 Aug;16(8):2330-7. Epub 2005 Jun 23.

14.

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

Willnow T, Antignac C, Brändli A, Christensen E, Cox R, Davidson D, Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A, Meij I.

Organogenesis. 2005 Apr;2(2):42-7.

15.

Megalin mediates renal uptake of heavy metal metallothionein complexes.

Klassen RB, Crenshaw K, Kozyraki R, Verroust PJ, Tio L, Atrian S, Allen PL, Hammond TG.

Am J Physiol Renal Physiol. 2004 Sep;287(3):F393-403. Epub 2004 May 4.

16.

Characterization of a plasma membrane-resident albumin-binding protein associated with the proliferation of estrogen-target, serum-sensitive cells.

Powell CE, Soto AM, Michaelson CL, Diba F, Mounier F, Verroust PJ, Sonnenschein C.

Steroids. 2003 Aug;68(6):487-96.

PMID:
12906933
17.

[Cubilin: physiopathologic role and relationship with megalin].

Verroust PJ, Kozyraki R.

Med Sci (Paris). 2003 Mar;19(3):337-43. Review. French.

18.

Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin.

Gburek J, Birn H, Verroust PJ, Goj B, Jacobsen C, Moestrup SK, Willnow TE, Christensen EI.

Am J Physiol Renal Physiol. 2003 Sep;285(3):F451-8. Epub 2003 Apr 29.

19.

Megalin and cubilin, role in proximal tubule function and during development.

Christensen EI, Verroust PJ.

Pediatr Nephrol. 2002 Dec;17(12):993-9. Epub 2002 Nov 7. Review.

PMID:
12478347
20.

Megalin and cubilin--the story of two multipurpose receptors unfolds.

Verroust PJ, Christensen EI.

Nephrol Dial Transplant. 2002 Nov;17(11):1867-71. Review. No abstract available.

PMID:
12401836
21.

Pathophysiology of cubilin: of rats, dogs and men.

Verroust PJ.

Nephrol Dial Transplant. 2002;17 Suppl 9:55-6. Review.

PMID:
12386289
22.

The tandem endocytic receptors megalin and cubilin are important proteins in renal pathology.

Verroust PJ, Birn H, Nielsen R, Kozyraki R, Christensen EI.

Kidney Int. 2002 Sep;62(3):745-56. Review.

23.

Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin.

Gburek J, Verroust PJ, Willnow TE, Fyfe JC, Nowacki W, Jacobsen C, Moestrup SK, Christensen EI.

J Am Soc Nephrol. 2002 Feb;13(2):423-30.

24.

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

Nykjaer A, Fyfe JC, Kozyraki R, Leheste JR, Jacobsen C, Nielsen MS, Verroust PJ, Aminoff M, de la Chapelle A, Moestrup SK, Ray R, Gliemann J, Willnow TE, Christensen EI.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13895-900.

25.

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.

Kozyraki R, Fyfe J, Verroust PJ, Jacobsen C, Dautry-Varsat A, Gburek J, Willnow TE, Christensen EI, Moestrup SK.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12491-6. Epub 2001 Oct 16.

26.

Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells.

Lebeau C, Arlt VM, Schmeiser HH, Boom A, Verroust PJ, Devuyst O, Beauwens R.

Kidney Int. 2001 Oct;60(4):1332-42.

27.
28.
29.

Physiopathologic role of cubilin and megalin.

Verroust PJ, Kozyraki R, Hammond TG, Moestrup SK, Christensen EI.

Adv Nephrol Necker Hosp. 2000;30:127-45. Review. No abstract available.

PMID:
11068639
30.

Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.

Zhai XY, Nielsen R, Birn H, Drumm K, Mildenberger S, Freudinger R, Moestrup SK, Verroust PJ, Christensen EI, Gekle M.

Kidney Int. 2000 Oct;58(4):1523-33.

31.

Evidence for the role of megalin in renal uptake of transthyretin.

Sousa MM, Norden AG, Jacobsen C, Willnow TE, Christensen EI, Thakker RV, Verroust PJ, Moestrup SK, Saraiva MJ.

J Biol Chem. 2000 Dec 8;275(49):38176-81.

32.

Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin.

Kristiansen M, Aminoff M, Jacobsen C, de La Chapelle A, Krahe R, Verroust PJ, Moestrup SK.

Blood. 2000 Jul 15;96(2):405-9.

33.

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.

Birn H, Fyfe JC, Jacobsen C, Mounier F, Verroust PJ, Orskov H, Willnow TE, Moestrup SK, Christensen EI.

J Clin Invest. 2000 May;105(10):1353-61.

34.

Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules.

Birn H, Vorum H, Verroust PJ, Moestrup SK, Christensen EI.

J Am Soc Nephrol. 2000 Feb;11(2):191-202.

35.

Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding.

Kristiansen M, Kozyraki R, Jacobsen C, Nexø E, Verroust PJ, Moestrup SK.

J Biol Chem. 1999 Jul 16;274(29):20540-4.

36.

The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

Kozyraki R, Fyfe J, Kristiansen M, Gerdes C, Jacobsen C, Cui S, Christensen EI, Aminoff M, de la Chapelle A, Krahe R, Verroust PJ, Moestrup SK.

Nat Med. 1999 Jun;5(6):656-61.

PMID:
10371504
37.

Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1.

Aminoff M, Carter JE, Chadwick RB, Johnson C, Gräsbeck R, Abdelaal MA, Broch H, Jenner LB, Verroust PJ, Moestrup SK, de la Chapelle A, Krahe R.

Nat Genet. 1999 Mar;21(3):309-13.

PMID:
10080186
38.

Myeloma light chains are ligands for cubilin (gp280).

Batuman V, Verroust PJ, Navar GL, Kaysen JH, Goda FO, Campbell WC, Simon E, Pontillon F, Lyles M, Bruno J, Hammond TG.

Am J Physiol. 1998 Aug;275(2):F246-54. doi: 10.1152/ajprenal.1998.275.2.F246.

PMID:
9691015
39.

The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region.

Kozyraki R, Kristiansen M, Silahtaroglu A, Hansen C, Jacobsen C, Tommerup N, Verroust PJ, Moestrup SK.

Blood. 1998 May 15;91(10):3593-600. Erratum in: Blood 1998 Oct 1;92(7):2608.

40.

Membrane potential mediates H(+)-ATPase dependence of "degradative pathway" endosomal fusion.

Hammond TG, Goda FO, Navar GL, Campbell WC, Majewski RR, Galvan DL, Pontillon F, Kaysen JH, Goodwin TJ, Paddock SW, Verroust PJ.

J Membr Biol. 1998 Mar 15;162(2):157-67.

PMID:
9538509
41.

The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins.

Moestrup SK, Kozyraki R, Kristiansen M, Kaysen JH, Rasmussen HH, Brault D, Pontillon F, Goda FO, Christensen EI, Hammond TG, Verroust PJ.

J Biol Chem. 1998 Feb 27;273(9):5235-42.

42.

Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein.

Birn H, Verroust PJ, Nexo E, Hager H, Jacobsen C, Christensen EI, Moestrup SK.

J Biol Chem. 1997 Oct 17;272(42):26497-504.

43.

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor.

Seetharam B, Christensen EI, Moestrup SK, Hammond TG, Verroust PJ.

J Clin Invest. 1997 May 15;99(10):2317-22.

44.

Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin.

Hammond TG, Majewski RR, Kaysen JH, Goda FO, Navar GL, Pontillon F, Verroust PJ.

Am J Physiol. 1997 Jan;272(1 Pt 2):F117-23.

PMID:
9039057
45.

Megalin/gp330 mediates uptake of albumin in renal proximal tubule.

Cui S, Verroust PJ, Moestrup SK, Christensen EI.

Am J Physiol. 1996 Oct;271(4 Pt 2):F900-7.

PMID:
8898021
46.

Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.

Moestrup SK, Birn H, Fischer PB, Petersen CM, Verroust PJ, Sim RB, Christensen EI, Nexø E.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8612-7.

47.

[Vesicular flow in epithelial cells: physiopathologic importance of two multiligand receptors].

Verroust PJ, Christensen EI, Hammond TG.

Bull Acad Natl Med. 1996 Jun-Jul;180(6):1187-97; discussion 1197-8. French.

PMID:
8991602
48.

[Endocytosis and receptors: molecular and physiological aspects].

Verroust PJ, Christensen EI, Hammond TG.

Nephrologie. 1996;17(7):359-64. Review. French.

PMID:
9019662
49.

Unusual processing of GP280, a protein associated with the intermicrovillar areas of yolk sac epithelial cells: plasma membrane delivery of immature protein.

Baricault L, Galceran M, Ronco PM, Trugnan G, Verroust PJ.

Biochem Biophys Res Commun. 1995 Jul 17;212(2):353-9.

PMID:
7626048
50.

Supplemental Content

Loading ...
Support Center