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Items: 44


TCR Sequencing Reveals the Distinct Development of Fetal and Adult Human Vγ9Vδ2 T Cells.

Papadopoulou M, Tieppo P, McGovern N, Gosselin F, Chan JKY, Goetgeluk G, Dauby N, Cogan A, Donner C, Ginhoux F, Vandekerckhove B, Vermijlen D.

J Immunol. 2019 Aug 14. pii: ji1900592. doi: 10.4049/jimmunol.1900592. [Epub ahead of print]


Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells.

Di Lorenzo B, Simões AE, Caiado F, Tieppo P, Correia DV, Carvalho T, da Silva MG, Déchanet-Merville J, Schumacher TN, Prinz I, Norell H, Ravens S, Vermijlen D, Silva-Santos B.

Cancer Immunol Res. 2019 Apr;7(4):552-558. doi: 10.1158/2326-6066.CIR-18-0647. Epub 2019 Mar 20.


Accumulation of IL-17+ Vγ6+ γδ T cells in pregnant mice is not associated with spontaneous abortion.

Polese B, Gridelet V, Perrier d'Hauterive S, Renard C, Munaut C, Martens H, Vermijlen D, King IL, Jacobs N, Geenen V.

Clin Transl Immunology. 2018 Jan 29;7(1):e1008. doi: 10.1002/cti2.1008. eCollection 2018.


γδ T cell responses: How many ligands will it take till we know?

Vermijlen D, Gatti D, Kouzeli A, Rus T, Eberl M.

Semin Cell Dev Biol. 2018 Dec;84:75-86. doi: 10.1016/j.semcdb.2017.10.009. Epub 2018 Feb 5. Review.


Human papillomavirus oncoproteins induce a reorganization of epithelial-associated γδ T cells promoting tumor formation.

Van Hede D, Polese B, Humblet C, Wilharm A, Renoux V, Dortu E, de Leval L, Delvenne P, Desmet CJ, Bureau F, Vermijlen D, Jacobs N.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9056-E9065. doi: 10.1073/pnas.1712883114. Epub 2017 Oct 10.


The checkpoint for agonist selection precedes conventional selection in human thymus.

Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, Van Caeneghem Y, De Munter S, Weening K, Bonte S, Leclercq G, Taghon T, Kerre T, Saeys Y, Van Dorpe J, Cheroutre H, Vandekerckhove B.

Sci Immunol. 2017 Feb 24;2(8). pii: eaah4232. doi: 10.1126/sciimmunol.aah4232.


Assessment of tumor-infiltrating TCRVγ9Vδ2 γδ lymphocyte abundance by deconvolution of human cancers microarrays.

Tosolini M, Pont F, Poupot M, Vergez F, Nicolau-Travers ML, Vermijlen D, Sarry JE, Dieli F, Fournié JJ.

Oncoimmunology. 2017 Feb 6;6(3):e1284723. doi: 10.1080/2162402X.2017.1284723. eCollection 2017.


Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.

Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B.

Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017.


Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early Life.

Roger T, Schlapbach LJ, Schneider A, Weier M, Wellmann S, Marquis P, Vermijlen D, Sweep FC, Leng L, Bucala R, Calandra T, Giannoni E.

Front Immunol. 2017 Jan 25;8:26. doi: 10.3389/fimmu.2017.00026. eCollection 2017.


Corrigendum: Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes Are More Innate Than Others.

Vermijlen D, Prinz I.

Front Immunol. 2015 Dec 14;6:624. doi: 10.3389/fimmu.2015.00624. eCollection 2015.


γδ T cells confer protection against murine cytomegalovirus (MCMV).

Khairallah C, Netzer S, Villacreces A, Juzan M, Rousseau B, Dulanto S, Giese A, Costet P, Praloran V, Moreau JF, Dubus P, Vermijlen D, Déchanet-Merville J, Capone M.

PLoS Pathog. 2015 Mar 6;11(3):e1004702. doi: 10.1371/journal.ppat.1004702. eCollection 2015 Mar.


Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire.

Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, Marchant A, Vermijlen D.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):E556-65. doi: 10.1073/pnas.1412058112. Epub 2015 Jan 23.


Immunity to cytomegalovirus in early life.

Huygens A, Dauby N, Vermijlen D, Marchant A.

Front Immunol. 2014 Oct 30;5:552. doi: 10.3389/fimmu.2014.00552. eCollection 2014. Review.


Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others.

Vermijlen D, Prinz I.

Front Immunol. 2014 Oct 10;5:486. doi: 10.3389/fimmu.2014.00486. eCollection 2014. Review. Erratum in: Front Immunol. 2015;6:624.


Do PI3-kinase mutations drive T cells insane?

Vermijlen D, Braun MY, Marchant A.

Cell Mol Immunol. 2014 Jul;11(4):320-2. doi: 10.1038/cmi.2014.11. Epub 2014 Mar 3. No abstract available.


γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia.

Scheper W, van Dorp S, Kersting S, Pietersma F, Lindemans C, Hol S, Heijhuurs S, Sebestyen Z, Gründer C, Marcu-Malina V, Marchant A, Donner C, Plachter B, Vermijlen D, van Baarle D, Kuball J.

Leukemia. 2013 Jun;27(6):1328-38. doi: 10.1038/leu.2012.374. Epub 2013 Jan 1.


IL-23R and TCR signaling drives the generation of neonatal Vgamma9Vdelta2 T cells expressing high levels of cytotoxic mediators and producing IFN-gamma and IL-17.

Moens E, Brouwer M, Dimova T, Goldman M, Willems F, Vermijlen D.

J Leukoc Biol. 2011 May;89(5):743-52. doi: 10.1189/jlb.0910501. Epub 2011 Feb 17.


In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients.

Meraviglia S, Eberl M, Vermijlen D, Todaro M, Buccheri S, Cicero G, La Mendola C, Guggino G, D'Asaro M, Orlando V, Scarpa F, Roberts A, Caccamo N, Stassi G, Dieli F, Hayday AC.

Clin Exp Immunol. 2010 Aug;161(2):290-7. doi: 10.1111/j.1365-2249.2010.04167.x. Epub 2010 May 10.


Human cytomegalovirus elicits fetal gammadelta T cell responses in utero.

Vermijlen D, Brouwer M, Donner C, Liesnard C, Tackoen M, Van Rysselberge M, Twité N, Goldman M, Marchant A, Willems F.

J Exp Med. 2010 Apr 12;207(4):807-21. doi: 10.1084/jem.20090348. Epub 2010 Apr 5.


Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells.

Van Coppernolle S, Verstichel G, Timmermans F, Velghe I, Vermijlen D, De Smedt M, Leclercq G, Plum J, Taghon T, Vandekerckhove B, Kerre T.

J Immunol. 2009 Oct 15;183(8):4859-70. doi: 10.4049/jimmunol.0900714.


Targeting human {gamma}delta} T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer.

Dieli F, Vermijlen D, Fulfaro F, Caccamo N, Meraviglia S, Cicero G, Roberts A, Buccheri S, D'Asaro M, Gebbia N, Salerno A, Eberl M, Hayday AC.

Cancer Res. 2007 Aug 1;67(15):7450-7.


Distinct cytokine-driven responses of activated blood gammadelta T cells: insights into unconventional T cell pleiotropy.

Vermijlen D, Ellis P, Langford C, Klein A, Engel R, Willimann K, Jomaa H, Hayday AC, Eberl M.

J Immunol. 2007 Apr 1;178(7):4304-14.


The integration of conventional and unconventional T cells that characterizes cell-mediated responses.

Pennington DJ, Vermijlen D, Wise EL, Clarke SL, Tigelaar RE, Hayday AC.

Adv Immunol. 2005;87:27-59. Review.


Interactions between rat colon carcinoma cells and Kupffer cells during the onset of hepatic metastasis.

Timmers M, Vekemans K, Vermijlen D, Asosingh K, Kuppen P, Bouwens L, Wisse E, Braet F.

Int J Cancer. 2004 Dec 10;112(5):793-802.


High-density oligonucleotide array analysis reveals extensive differences between freshly isolated blood and hepatic natural killer cells.

Vermijlen D, Seynaeve C, Luo D, Kruhøffer M, Eizirik DL, Ørntoft TF, Wisse E.

Eur J Immunol. 2004 Sep;34(9):2529-40.


Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway.

Vermijlen D, Luo D, Froelich CJ, Medema JP, Kummer JA, Willems E, Braet F, Wisse E.

Comp Hepatol. 2004 Jan 14;3 Suppl 1:S58. No abstract available.


Confocal laser scanning microscopic study of the killing of metastatic colon carcinoma cells by Kupffer cells in the early onset of hepatic metastasis.

Timmers M, Vekemans K, Vermijlen D, Zanger RD, Wisse E, Braet F.

Comp Hepatol. 2004 Jan 14;3 Suppl 1:S50. No abstract available.


Cytotoxic reactions of CC531s towards liver sinusoidal endothelial cells: a microscopical study.

Vekemans K, Timmers M, Vermijlen D, Zanger RD, Wisse E, Braet F.

Comp Hepatol. 2004 Jan 14;3 Suppl 1:S49. No abstract available.


CC531s colon carcinoma cells induce apoptosis in rat hepatic endothelial cells by the Fas/FasL-mediated pathway.

Vekemans K, Timmers M, Vermijlen D, De Zanger R, Wisse E, Braet F.

Liver Int. 2003 Aug;23(4):283-93.


Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway.

Vermijlen D, Luo D, Froelich CJ, Medema JP, Kummer JA, Willems E, Braet F, Wisse E.

J Leukoc Biol. 2002 Oct;72(4):668-76.


Tracing DiO-labelled tumour cells in liver sections by confocal laser scanning microscopy.

Timmers M, Vermijlen D, Vekemans K, De Zanger R, Wisse E, Braet F.

J Microsc. 2002 Oct;208(Pt 1):65-74.


Organization of telomeres during the cell and life cycles of Trypanosoma brucei.

Pérez-Morga D, Amiguet-Vercher A, Vermijlen D, Pays E.

J Eukaryot Microbiol. 2001 Mar-Apr;48(2):221-6.


Is the presence of interleukin-2 receptor alpha in the serum of colorectal liver metastases patients derived from hepatic natural killer cells?

Vermijlen D, Luo D, Kruhøffer M, ØRntoft TF, Kuppen PJ, Wisse E.

Cancer Immunol Immunother. 2002 Jul;51(5):291-2. Epub 2002 May 1. No abstract available.


Participation of CD45, NKR-P1A and ANK61 antigen in rat hepatic NK cell (pit cell)mediated target cell cytotoxicity.

Luo DZ, Vermijlen D, Ahishali B, Triantis V, Vanderkerken K, Kuppen PJ, Wisse E.

World J Gastroenterol. 2000 Aug;6(4):546-552.


On the cell biology of pit cells, the liver-specific NK cells.

Luo DZ, Vermijlen D, Ahishali B, Triantis V, Plakoutsi G, Braet F, Vanderkerken K, Wisse E.

World J Gastroenterol. 2000 Feb;6(1):1-11. No abstract available.


Early detection of cytotoxic events between hepatic natural killer cells and colon carcinoma cells as probed with the atomic force microscope.

Braet F, Vermijlen D, Bossuyt V, De Zanger R, Wisse E.

Ultramicroscopy. 2001 Nov;89(4):265-73.


Rat hepatic natural killer cells (pit cells) express mRNA and protein similar to in vitro interleukin-2 activated spleen natural killer cells.

Luo D, Vanderkerken K, Chen MC, Vermijlen D, Asosingh K, Willems E, Triantis V, Eizirik DL, Kuppen PJ, Wisse E.

Cell Immunol. 2001 May 25;210(1):41-8.


Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.

Vermijlen D, Froelich CJ, Luo D, Suarez-Huerta N, Robaye B, Wisse E.

Cancer Immunol Immunother. 2001 Jun;50(4):212-7.


Involvement of LFA-1 in hepatic NK cell (pit cell)-mediated cytolysis and apoptosis of colon carcinoma cells.

Luo D, Vermijlen D, Vanderkerken K, Kuppen PJ, Seynaeve C, Eddouks M, Baekeland M, Wisse E.

J Hepatol. 1999 Jul;31(1):110-6.


Pit cells (Hepatic natural killer cells) of the rat induce apoptosis in colon carcinoma cells by the perforin/granzyme pathway.

Vermijlen D, Luo D, Robaye B, Seynaeve C, Baekeland M, Wisse E.

Hepatology. 1999 Jan;29(1):51-6.


On the function of pit cells, the liver-specific natural killer cells.

Wisse E, Luo D, Vermijlen D, Kanellopoulou C, De Zanger R, Braet F.

Semin Liver Dis. 1997;17(4):265-86. Review.


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